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研究领域

主要从事心脑血管疾病发病机制的药理学研究、天然药物活性成分分离提取及药效学评价。

近期论文

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1. Geng B, Cai Y, Gao S, Lu J, Zhang L, Zou J, Liu M, Yu S, Ye J*, Liu P*. PARP-2 knockdown protects cardiomyocytes from hypertrophy via activation of SIRT1. Biochem Biophys Res Commun. 2013 Jan 18;430(3):944-50. 2. Cai Y, Yu SS, Chen TT, Gao S, Geng B, Yu Y, Ye JT*, Liu PQ*. EGCG inhibits CTGF expression via blocking NF-κB activation in cardiac fibroblast. Phytomedicine. 2013 Jan 15;20(2):106-13. 3. Yu SS, Cai Y, Ye JT, Pi RB, Chen SR, Liu PQ, Shen XY, Ji Y. Sirtuin 6 protects cardiomyocytes from hypertrophy in vitro via inhibition of NF-κB-dependent transcriptional activity. British Journal of Pharmacology. 2013 Jan;168(1):117-28. 4. Cai Y, Yu SS, Chen SR, Pi RB, Gao S, Li H, Ye JT*, Liu PQ*. Nmnat2 protects cardiomyocytes from hypertrophy via activation of SIRT6. FEBS Letters. 2012 Mar 23;586(6):866-74. . 5. Mao X, Ye J, Zhou S, Pi R, Dou J, Zang L, Chen X, Chao X, Li W, Liu M, Liu P. The effects of chronic copper exposure on the amyloid protein metabolisim associated genes' expression in chronic cerebral hypoperfused rats. Neuroscience Letters. 2012 Jun 14;518(1):14-8. 6. Zhou WM, He RR, Ye JT, Zhang N, Liu DY. Synthesis and biological evaluation of new 5-fluorouracil-substituted ampelopsin derivatives. Molecules. 2010 Mar 24;15(4):2114-23. 7. Chen XH, Lin ZZ, Liu AM, Ye JT, Luo Y, Luo YY, Mao XX, Liu PQ, Pi RB. The orally combined neuroprotective effects of sodium ferulate and borneol against transient global ischaemia in C57 BL/6J mice. Journal of Pharmacy and Pharmacology. 2010 Jul;62(7):915-23. 8. Ye JT, Pi RB, Mao XX, Chen XH, Qin J, Xu SW, Liu PQ. Alterations in mRNA expression of BACE1, cathepsin B, and glutaminyl cyclase in mice ischemic brain. Neuroreport. 2009 Oct 28;20(16):1456-60. 9. Ye J, Guan Y, Zeng S, Liu D. Ampelopsin prevents apoptosis induced by H2O2 in MT-4 lymphocytes. Planta Medica. 2008 Feb;74(3):252-7. 10. 叶建涛, 周伟明, 何蓉蓉, 刘德育. 蛇葡萄素与5-氟尿嘧啶拼合物的合成及其抗肿瘤活性. 时珍国医国药. 2012年5月. 23(5): 1143-5. 11. 叶建涛, 郑义磊, 刘德育. 蛇葡萄素对K562/ADR细胞耐药性的逆转作用及机制研究. 中国中药杂志. 2009年3月. 34(6):761-5. 12. 罗德凤, 叶建涛, 张毅珊, 刘德育. 人参皂苷Rd固体脂质纳米粒的体外释放和大鼠的在体吸收. 中国药理学通报. 2009年7月. 25(7):923-6 .

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