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个人简介

杨运煌男,博士,研究员,2005年于中国科学院武汉物理与数学研究所获博士学位。2005年4月至2009年2月在美国SchoolofMedicine,WayneStateUniversity从事博士后工作。2009年3月至2014年12月在MiamiUniversity,NortheastStructuralGenomics(NESG)consortium从事高级研究学者工作。2014年12月任中科院武汉物理与数学研究所研究员。长期从事基于基因组学的生物大分子溶液结构,动力学和功能研究,发表论文30余篇,其中第一作者论文11篇。

研究领域

(1)应用磁共振波谱(NMR)和其它生物物理技术,发展生物大分子复合物(RNA/DNA/protein-proteincomplex)的结构和动力学研究的新方法 (2)基于基因组学的生物大分子结构和功能研究 (3)与癌症相关(HumanCancerPathwayProteinInteractionNetwork,HCPIN)的蛋白质结构和功能研究

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

YunhuangYang,TheresaA.Ramelot,Hsiau-WeiLee,RongXiao,JohnK.Everett,GaetanoT.Montelione,JamesH.Prestegard,andMichaelA.Kennedy.SolutionstructureofaC-terminalfragment(175-257)ofCV_0373proteinfromChromobacteriumviolaceumadoptsawingedhelix-turn-helix(wHTH)fold.JournalofBiomolecularNMR,60:197-202,2014. YunhuangYang,TheresaA.Ramelot,Hsiau-WeiLee,RongXiao,JohnK.Everett,GaetanoT.Montelione,JamesH.Prestegard,andMichaelA.Kennedy.SolutionstructureofthefreeZadomainofhumanDLM-1(ZBP1/DAI),aZ-DNAbindingdomain.JournalofBiomolecularNMR,60:189-195,2014. YunhuangYang,TheresaA.Ramelot,ShuisongNi,RobertM.McCarrick,andMichaelA.Kennedy.ApplicationsofNMR-basedPREandEPR-basedDEERspectroscopytohomodimerchainexchangecharacterizationandstructuredetermination.MethodsinMolecularBiology,215-227,2014. YunhuangYang,TheresaA.Ramelot,ShuisongNi,RobertM.McCarrick,andMichaelA.Kennedy.Measurementofrateconstantsforhomodimersubunitexchangeusingdoubleelectron-electronresonanceandparamagneticrelaxationenhancements.JournalofBiomolecularNMR,55,47-58,2013. YunhuangYang,TheresaA.Ramelot,JohnR.Cort,MaiteGarcia,AdelindaYee,CherylH.Arrowsmith,andMichaelA.Kennedy.SolutionNMRstructureofhypotheticalproteinCV_2116encodedbyaviralprophageelementinChromobacteriumviolaceum.InternationalJournalofMolecularSciences,13,7354-7364,2012. YunhuangYang,TheresaA.Ramelot,JohnR.Cort,HuangWang,ColleenCiccosanti,MeiJiang,HaleemaJanjua,ThomasB.Acton,RongXiao,JohnK.Everett,GaetanoT.Montelione,andMichaelA.Kennedy.SolutionNMRstructureofDsy0195homodimerfromDesulfitobacteriumhafniense:firststructurerepresentativeoftheYabPdomainfamilyofproteinsinvolvedinsporecoatassembly.JournalofStructuralandFunctionalGenomics;12,175-179,2011. YunhuangYang,TheresaA.Ramelot,JohnR.Cort,DongyanWang,ColleenCiccosanti,KeithHamilton,RajeshNair,BurkhardRost,ThomasB.Acton,RongXiao,JohnK.Everett,GaetanoT.Montelione,andMichaelA.Kennedy.SolutionNMRstructureofphotosystemIIreactioncenterproteinPsb28fromSynechocystissp.strainPCC6803.Proteins:Structure,Function,andBioinformatics,79,340-344,2011. YunhuangYang,TheresaA.Ramelot,RobertM.McCarrick,ShuisongNi,ErikA.Feldmann,JohnR.Cort,HuangWang,ColleenCiccosanti,MeiJiang,HaleemaJanjua,ThomasB.Acton,RongXiao,JohnK.Everett,GaetanoT.Montelione,andMichaelA.Kennedy.CombiningNMRandEPRmethodsforhomodimerproteinstructuredetermination.JournalofAmericanChemicalSociety,132,11910-11913,2010. YunhuangYang,DavidHoyt,andJianjunWang.AcompleteNMRspectralassignmentofthelipid-freemouseapolipoproteinA-I(apoAI)C-terminaltruncationmutant,apoAI(1-216).BiomolecularNMRAssignments,1,109-111,2007. YunhuangYang,GuoyunBai,XuZhang,ChaohuiYe,andMailiLiu.1HNMRspectroscopicevidenceofinteractionbetweenibuprofenandlipoproteinsinhumanbloodplasm.AnalyticalBiochemistry,324,292-297,2004.

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