Fukuyama, Tohru - Rice University - Department of Chemistry

研究领域

At the University of Tokyo our major research efforts are directed toward total synthesis of complex natural products with interesting biological activities.

近期论文

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"Total Synthesis of Lyconadins A-C" Takuya Nishimura, Aditya K. Unni, Satoshi Yokoshima, Tohru Fukuyama J. Am. Chem. Soc., ASAP, (doi: 10.1021/ja312065m) "2-Pyridone Synthesis Using 2-(Phenylsulfinyl)acetamide" Masaya Fujii, Takuya Nishimura, Takahiro Koshiba, Satoshi Yokoshima, Tohru Fukuyama Org. Lett., 15, 232 (2013) (doi: 10.1021/ol303320c) "Modified McFadyen-Stevens Reaction for a Versatile Synthesis of Aliphatic/Aromatic Aldehydes: Design, Optimization, and Mechanistic Investigations" Yuri Iwai, Takashi Ozaki, Ryo Takita, Masanobu Uchiyama, Jun Shimokawa, Tohru Fukuyama Chem. Sci., ASAP (doi: 10.1039/C2SC22045H) "Activity-Dependent Proteolytic Cleavage of Neuroligin-1" Kunimichi Suzuki, Yukari Hayashi, Soichiro Nakahara, Hiroshi Kumazaki, Johannes Prox Keisuke Horiuchi, Mingshuo Zeng, Shun Tanimura, Yoshitake Nishiyama, Satoko Osawa Atsuko Sehara-Fujisawa, Paul Saftig, Satoshi Yokoshima, Tohru Fukuyama, Norio Matsuki Ryuta Koyama, Taisuke Tomita, Takeshi Iwatsubo Neuron, 76, 410 (2012) (doi: 10.1016/j.neuron.2012.10.003) "Total Synthesis of (–)-Lycoposerramine-S" Naoaki Shimada, Yuzo Abe, Satoshi Yokoshima, Tohru Fukuyama Angew. Chem. Int. Ed., 2012 (doi: 10.1002/anie.201206863) "Synthetic Studies on Chartelline C: Stereoselective Construction of the Core Skeleton" Kotaro Iwasaki, Rentaro Kanno, Toshiharu Morimoto, Tohru Yamashita Satoshi Yokoshima, Tohru Fukuyama Angew. Chem. Int. Ed., 51, 9160 (2012) (doi: 10.1002/anie.201204726) "Total Synthesis of (–)-Lemonomycin" Atsushi Yoshida, Michinori Akaiwa, Tomohiro Asakawa, Yoshitaka Hamashima Satoshi Yokoshima, Tohru Fukuyama, Toshiyuki Kan Chem. Eur. J., 18, 11192 (2012) (doi: 10.1002/chem.201202073q) "Total Synthesis of (–)-Isoschizogamine" Yusuke Miura, Noriyuki Hayashi, Satoshi Yokoshima, Tohru Fukuyama J. Am. Chem. Soc., 134, 11995 (2012) (doi: 10.1021/ja305856q) "Synthetic Studies toward Ecteinascidin 743 (Trabectedin)" Takahiro Imai, Hiyoku Nakata, Satoshi Yokoshima, Tohru Fukuyama Synthesis, 44, 2743 (2012) (doi: 10.1055/s-0032-1316579) "Convenient Synthesis of α-Diazoacetates from α-Bromoacetates and N,N'-Ditosylhydrazine: Preparation of Benzyl Diazoacetate" Eiji Ideue, Tatsuya Toma, Jun Shimokawa, Tohru Fukuyama Org. Synth., 89, 501 (2012) "Efficient Synthesis of Oxime Using O-TBS-N-Tosylhydroxylamine: Preparation of (2Z)-4-(Benzyloxy)but-2-enal Oxime" Katsushi Kitahara, Tatsuya Toma, Jun Shimokawa, Tohru Fukuyama Org. Synth., 89, 480 (2012) "Total Synthesis of Gelsemoxonine" Jun Shimokawa, Takaaki Harada, Satoshi Yokoshima and Tohru Fukuyama Pure Appl. Chem., 84, 1643 (2012) (doi: 10.1351/PAC-CON-11-10-25) "A Practical Preparation of Highly Versatile N-Acylpyrroles from 2,4,4-Trimethoxybutan-1-amine" Tomoaki Maehara, Rentaro Kanno, Satoshi Yokoshima, and Tohru Fukuyama Org. Lett., 14, 1946 (2012) (doi: 10.1021/ol3005613) "Total Synthesis of (–)-Anisatin" Akihiro Ogura, Kohei Yamada, Satoshi Yokoshima, and Tohru Fukuyama Org. Lett., 14, 1632 (2012) (doi: 10.1021/ol300390k) "Total Syntheses of All the Amathaspiramides" Koji Chiyoda, Jun Shimokawa, Tohru Fukuyama Angew. Chem. Int. Ed., 51, 2505 (2012) (doi: 10.1002/anie.201109221) "A Practical Synthesis of (–)-Kainic Acid" Satoshi Takita, Satoshi Yokoshima, Tohru Fukuyama Synthesis, 3848 (2011) (doi: 10.1055/s-0031-1289570) "Total Synthesis of Gelsemoxonine," Jun Shimokawa, Takaaki Harada, Satoshi Yokoshima, and Tohru Fukuyama J. Am. Chem. Soc., 133, 17634-17637 (2011) (doi: 10.1021/ja109516f) "Phenylpiperidine-type γ-secretase modulators target the transmembrane domain 1 of presenilin 1" Yu Ohki, Takuya Higo, Kengo Uemura, Naoaki Shimada, Satoko Osawa, Oksana Berezovska, Satoshi Yokoshima, Tohru Fukuyama, Taisuke Tomita and Takeshi Iwatsubo EMBO Journal, 30, 4815 (2011) (doi: 10.1038/emboj.2011.372) "Total Synthesis of (–)-Histrionicotoxin" Yohei Adachi, Noriyuki Kamei, Satoshi Yokoshima, and Tohru Fukuyama Org. Lett., 13, 4446-4449 (2011) (doi: 10.1021/ol2018032) "Copper-Mediated Aryl Amination: In Situ Generation of an Active Copper(I) Species" Takashi Komori, Nobuhiro Satoh, Satoshi Yokoshima, Tohru Fukuyama Synlett, 1859-1862 (2011) (doi: 10.1055/s-0030-1260954) "Total Synthesis of Tryprostatins A and B," Takayuki Yamakawa, Eiji Ideue, Yuzo Iwaki, Ayumu Sato, Hidetoshi Tokuyama, Jun Shimokawa, and Tohru Fukuyama Tetrahedron, 67, 6547-6560 (2011) (doi: 10.1016/j.tet.2011.05.112)