Ball, Zachary T. - Rice University - Department of Chemistry

个人简介

A.B. Chemistry (1999) Harvard University Ph.D. Chemistry (2004) Stanford University

研究领域

Our research focuses on the design of transition-metal complexes with unique structure and function, including transition-metal complexes with applications in chemical biology and medicinal chemistry. Current projects center around catalysis, de novo design of metalloenzyme-like function, and organometallic tools for chemical biology.

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

A Naturally Encoded Dipeptide Handle for Bioorthogonal Chan-Lam Coupling Ohata, J., Zeng, Y., Segatori, L., Ball, Z.T. Angew. Chem. Int. Ed., 2018, ASAP A three-component organometallic tyrosine bioconjugation Ohata, J., Miller, M.K., Mountain, C., Ball, Z.T. Angew. Chem. Int. Ed., 2018, ASAP A hexa-rhodium metallopeptide catalyst for site-specific functionalization of rhodium antibodies Ohata, J., Ball, Z.T. J. Am. Chem. Soc., 2017, 139, (36), 12617–12622. Programming Post-TranslationalControl over the Metabolic Labeling of Cellular Proteins with a Noncanonical Amino Acid Thomas, E.; Pandey, N.; Knudsen, S.; Ball, Z.T.; Silberg, J. ACS Synth. Biol. , 2017, 6, (8), 1572–1583 Ascorbate as a pro-oxidant: mild N-terminal modification with vinylboronic acid Ohata, J., Ball, Z.T. Chem. Commun., 2016, 53, 1622–1625. Designing selectivity in dirhodium metallopeptide catalysts for protein modification Martin, S.C.; Vohidov, F.; Wang, H.; Knudsen, S.; Marzec, A.A.; Ball, Z.T. Bioconj. Chem., 2016, 28, 659–665. Chemical Posttranslational Modification with Designed Rhodium(II) Catalysts. Martin, S.C., Minus, M.B.; Ball, Z.T. In Methods in Enzymology, Vol. 580. Pecoraro, V., Ed.; Academic Press: 2016; 1-19. z Assessing the intracellular fate of rhodium(II) complexes. Minus, M.B., Kang, M.K., Knudsen, S.E.; Liu, W., Krueger, M.J.; Redell, M.S.; Ball, Z.T. Chem. Commun., 2016, 52, 11685–11688. Histidine-directed arylation/alkenylation of backbone N-H bonds mediated by copper(II). Ohata, J.; Minus, M.B.; Abernathy, M.E.; Ball, Z.T. J. Am. Chem. Soc., 2016, 138, 7472-7475. Rhodium(II) proximity-labeling identifies a novel target site on STAT3 for inhibitors with potent anti-leukemia activity. Minus, M.B.; Liu, W.; Vohidov, F.; Kasembeli, M.M.; Long, X.; Krueger, M.; Stevens, A.; Kolosov, M.I.; Tweardy, D.J.; Redell, M.S.; Ball, Z.T. Angew. Chem. Int. Ed., 2015, 54, 13085-13089. Designing enzyme-like catalysts: A rhodium(II) metallopeptide case study. Vohidov, F.; Popp, B.V.; Ball, Z.T. In Proceedings of the 24th American Peptide Symposium. Orlando, June 20-25, 2015; Srivastava, V., Yudin, A., Lebl, M., Eds.; American Peptide Society: 2015; 24-26. Convenient analysis of protein modification by chemical blotting with fluorogenic "click" reagents. Ohata, J.; Vohidov, F.; Ball, Z.T. Mol. Biosyst., 2015, 11, 2846-2849. Luminogenic iridium azide complexes. Ohata, J.; Vohidov, F.; Aliyan, A.; Huang, K.; Marti, A.A.; Ball, Z.T. Chem. Commun., 2015, 51, 15192-15195. Potent and selective inhibition of SH3 domains with dirhodium metalloinhibitors. Vohidov, F.; Knudsen, S.E.; Leonard, P.G.; Ohata, J.; Wheadon, M.J.; Popp, B.V.; Ladbury, J.E.; Ball, Z.T. Chem. Sci., 2015, 6, 4778-4783. Molecular recognition in protein modification with rhodium metallopeptides. Ball, Z.T. Curr. Opin. Chem. Biol., 2015, 25, 98-102. Metallopeptide catalyst design enables fine control in selective functionalization of natural SH3 domains. Vohidov, F.; Coughlin, J. M.; Ball, Z.T. Angew. Chem. Intl. Ed., 2015, 54, 4587-4591. Inhibiting prolyl isomerase activity by hybrid organic-inorganic molecules containing rhodium(II) fragments. Coughlin, J. M.; Kundu, R.; Cooper J.C.; Ball, Z.T. Bioorg. Med. Chem. Lett., 2014, 24, 5203-5206. Stabilization and functionalization of single-walled carbon nanotubes with polyvinylpyrrolidone copolymers for applications in aqueous media. Popp, B. V.; Miles, D. H.; Smith, J. A.; Fong, I. M.; Pasquali, M.; Ball, Z. T. J. Polym. Sci. Part A Polym. Chem., 2014, 53, 337-343. Mixed Bioengineering-Chemical Synthesis Approach for the Efficient Preparation of Δ7-Dafachronic Acid. Kinzurik, M.I.; Hristov, L.V.; Matsuda, S.P.T.; Ball, Z.T. Org. Lett., 2014, 16, 2188-2191. A tripodal peptide ligand for asymmetric Rh(II) catalysis highlights unique features of on-bead catalyst development. Sambasivan, R.; Zheng, W.; Burya, S.J.; Popp, B.V.; Turro, C.; Clementi, C.; Ball, Z.T. Chem. Sci., 2014, 5, 1401-1407.