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个人简介

教育经历 1987/9-1991/6 北京农业大学生物学院 学士 1991/9-1996/6 中国农业大学生物学院微生物系 理学博士 工作经历 1996-1998 中国农业大学农业生物技术国家重点实验室 讲师 1998-1999 法国巴斯德研究所 博士后 1999-2002 中国农业大学生物学院微生物系 副教授 2000-2004 美国康涅狄克大学(University of Connecticut)医学院,访问学者,进行细胞分裂机制的研究 2005-2008 美国北卡罗来纳州WAKE FOREST大学进行铜绿假单胞菌生物膜的研究 2008-2010 任职于俄亥俄州立大学(the Ohio State University),继续进行生物膜的研究 2010年5月至今 中科院微生物研究所,研究员、博士研究生导师

研究领域

细菌生物被膜的研究

近期论文

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1. Xu, A.#, Wang, D. #, Ding, Y., Zheng, Y., Wang, B., Wei, Q., Wang, S., Yang, L. and Ma, L.Z.* (2020) Integrated comparative genomic analysis and phenotypic profiling of Pseudomonas aeruginosa isolates from crude oil. Frontiers in Microbiology. 11:519. 2. Xu, A., Zhang, M., Du, W., Wang, D. * and Ma, L.Z.* (2020) A molecular mechanism for how sigma factor AlgT and transcriptional regulator AmrZ inhibit twitching motility in Pseudomonas aeruginosa. Environmental Microbiology. doi:10.1111/1462-2920.14985 3. Wei, Q., Bhasme, P., Wang, Z., Wang, L., Wang, S., Zeng, Y., Wang, Y., Ma, L.Z. *and Li, Y* (2020) Chinese medicinal herb extract inhibits PQS-mediated quorum sensing system in Pseudomonas aeruginosa. Journal of Ethnopharmacology, 248, 112272. 4. Bhasme, P., Wei, Q., Xu, A., Naqvi, S.T.A., Wang, D. and Ma, L.Z. * (2020) Evaluation and characterization of the predicted diguanylate cyclase-encoding genes in Pseudomonas aeruginosa. MicrobiologyOpen, 9(3): e975. 5. Zhao, T., Zhang, J., Tang, M., Ma, L.Z. * and Lei, X. * (2019) Development of an effective fluorescence probe for discovery of aminopeptidase inhibitors to suppress biofilm formation. The Journal of Antibiotics, 72, 461-468. 6. Wu, H., Wang, D., Tang, M. and Ma, L.Z. * (2019) The advance of assembly of exopolysaccharide Psl biosynthesis machinery in Pseudomonas aeruginosa. MicrobiologyOpen, 8(10): e857. 7. Wu, H., Qiao, S., Li, D., Guo, L., Zhu, M. and Ma, L.Z. * (2019) Crystal structure of the glycoside hydrolase PssZ from Listeria monocytogenes. Acta crystallographica. Section F, Structural Biology Communications, 75, 501-506. 8. Wei, Q., Leclercq, S., Bhasme, P., Xu, A., Zhu, B., Zhang, Y., Zhang, M., Wang, S. and Ma, L.Z. * (2019) Diguanylate Cyclases and Phosphodiesterases Required for Basal-Level c-di-GMP in Pseudomonas aeruginosa as Revealed by Systematic Phylogenetic and Transcriptomic Analyses. Applied and Environmental Microbiology, 16;85(21). pii: e01194-19 9. Liu, X., Wang, S., Xu, A., Zhang, L., Liu, H. and Ma, L.Z. * (2019) Biological synthesis of high-conductive pili in aerobic bacterium Pseudomonas aeruginosa. Applied Microbiology and Biotechnology, 103, 1535-1544. 10. Huang, Z., Wang, Y.H., Zhu, H.Z., Andrianova, E.P., Jiang, C.Y., Li, D., Ma, L., Feng, J., Liu, Z.P., Xiang, H*. et al. (2019) Cross Talk between Chemosensory Pathways That Modulate Chemotaxis and Biofilm Formation. mBio, 10(1). pii: e02876-18. 11. Zhao, T., Zhang, Y., Wu, H., Wang, D., Chen, Y., Zhu, M.J. and Ma, L.Z. * (2018) Extracellular aminopeptidase modulates biofilm development of Pseudomonas aeruginosa by affecting matrix exopolysaccharide and bacterial cell death. Environmental Microbiology Reports, 10, 583-593. 12. Zhang, J., He, J., Zhai, C., Ma, L.Z., Gu, L. and Zhao, K. * (2018) Effects of PslG on the Surface Movement of Pseudomonas aeruginosa. Applied and Environmental Microbiology, 84. 13. Zhai, C., Zhang, W., Zhang, J., Ma, L.Z. and Zhao, K. * (2018) Overshadow Effect of Psl on Bacterial Response to Physiochemically Distinct Surfaces Through Motility-Based Characterization. Frontiers in Cellular and Infection Microbiology, 8, 383. 14. Jin, Z., Nie, M., Hu, R., Zhao, T., Xu, J., Chen, D., Yun, J., Ma, L.Z. and Du, W. * (2018) Dynamic Sessile-Droplet Habitats for Controllable Cultivation of Bacterial Biofilm. Small (Weinheim an der Bergstrasse, Germany), 14, e1800658. 15. Yu, S., Zhang, M. and Ma, L. * (2017) [Anti-biofilm effects of Zn lactate.3H(2)O and SnF(2) on Pseudomonas aeruginosa, Acinetobacter baumannii and Streptococcus mutans]. Sheng wu gong cheng xue bao = Chinese Journal of Biotechnology, 33, 1478-1488. 16. Yu, S. and Ma, L. * (2017) [Iron uptake and biofilm formation in Pseudomonas aeruginosa]. Sheng wu gong cheng xue bao = Chinese Journal of Biotechnology, 33, 1489-1512. 17. Wang, D., Xu, A., Elmerich, C. and Ma, L.Z. * (2017) Biofilm formation enables free-living nitrogen-fixing rhizobacteria to fix nitrogen under aerobic conditions. The ISME Journal, 11, 1602-1613. 18. Qian, W. , Ma, L., Gu, L. and Zhang, L. (2017) [Preface for special issue on biofilm and c-di-GMP--Microbial society, c-di-GMP regulation, and new research techniques]. Sheng wu gong cheng xue bao = Chinese Journal of Biotechnology, 33, 1351-1356. 19. Zhu, B., Liu, C., Liu, S., Cong, H., Chen, Y., Gu, L. and Ma, L.Z. * (2016) Membrane association of SadC enhances its diguanylate cyclase activity to control exopolysaccharides synthesis and biofilm formation in Pseudomonas aeruginosa. Environmental Microbiology, 18, 3440-3452. 20. Yu, S., Wei, Q., Zhao, T., Guo, Y. and Ma, L.Z. * (2016) A Survival Strategy for Pseudomonas aeruginosa That Uses Exopolysaccharides To Sequester and Store Iron To Stimulate Psl-Dependent Biofilm Formation. Applied and Environmental Microbiology, 82, 6403-6413."

学术兼职

中国农业生物技术学会微生物生物技术分会理事 《FrontiersinMicrobialPhysiologyandMetabolism》编委

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