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个人简介

1988–1992年 山东建筑材料工业学院, 高分子材料, 学士 1994–1997年 日本国立鸟取大学, 分子工学, 硕士 1997–2000年 日本国立鸟取大学, 分子工学, 博士 2000–2001年 日本农林水产省农业生物资源研究所, 博士后 2001–2006年 日本北海道大学, 博士后 2007年–至今 中国科学院微生物研究所,中国科学院病原微生物与免疫学重点实验室,研究员,博士生导师,研究组长

研究领域

寡糖合成新方法研究 病原微生物抑制剂研究 微生物快速检测方法研究

近期论文

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Chen Wang, Shuihong Cheng, Yuanyuan Zhang, Yibo Ding, Huihui Chong, Hui Xing, Shibo Jiang, Xuebing Li,* Liying Ma.* Long-acting HIV-1 fusion inhibitory peptides and their mechanisms of action. Viruses 2019, 11(9), 811. Shuihong Cheng, Paeton L. Wantuch, Megan E. Kizer, Dustin R. Middleton, Ruitong Wang, Mikaela DiBello, Mingli Li, Xing Wang, Xuebing Li, Vasanthi Ramachandiran, Fikri Y. Avci, Fuming Zhang, Xing Zhang,* Robert J. Linhardt.* Glycoconjugate synthesis using 3.chemoselective ligation. Organic & Biomolecular Chemistry 2019, 17, 2646–2650. Zhenxing Zhang, Xiaoxiao Qi, Jinfeng Chai, Peixing Wu, Xun Lv*, Shuihong Cheng*, Xuebing Li*. Detection of glycan-binding proteins using glycan-functionalized quantum dots and gold nanoparticles. Journal of Carbohydrate Chemistry 2018, 1-11. Xun Lv, Hongzhi Cao, Baixue Lin,* Wei Wang, Wande Zhang, Qian Duan, Yong Tao, Xue-Wei Liu, Xuebing Li*. Synthesis of sialic acids, their derivatives and analogues using a whole-cell catalyst. Chemistry-A European Journal 2017, 23, 15143-15149. Longtang Zheng#, Jinhua Wei#, Xun Lv#, Yuhai Bi#, Peixing Wu, Zhenxing Zhang, Pengfei Wang, Ruichen Liu, Jingwen Jiang, Haolong Cong, Jingnan Liang, Wenwen Chen, Hongzhi Cao, Wenjun Liu, George F Gao, Yuguan Du g, Xingyu Jiang, and Xuebing Li*. Detection and differentiation of influenza viruses with glycan-functionalized gold nanoparticles. Biosensors and Bioelectronics 2017, 91, 46-52. Lifeng Fu, Yuhai Bi, Yan Wu, Shanshan Zhang, Jianxun Qi, Yan Li, Xuancheng Lu, Zhenning Zhang, Xun Lv, Jinghua Yan, George F. Gao, and Xuebing Li*. Structure-based tetravalent zanamivir with potent inhibitory activity against drug-resistant influenza viruses. Journal of Medicinal Chemistry 2016, 59(13), 6303-6312. Shuihong Cheng, Yan Wang, Zhenxing Zhang, Xun Lv, George F Gao, Yiming Shao, Liying Ma, and Xuebing Li *. Enfuvirtide-PEG conjugate: A potent HIV fusion inhibitor with improved pharmacokinetic properties, European Journal of Medicinal Chemistry 2016, 121, 232-237. Shuihong Cheng,Xuesong Chang,Yan Wang,George F Gao,Yiming Shao,Liying Ma,Xuebing Li*. Glycosylated enfuvirtide: a long-lasting glycopeptide with potent anti-HIV activity. Journal of Medicinal Chemistry 2015, 58(3), 1372-1379. Jinhua Wei#, Longtang Zheng#, Xun Lv#, Yuhai Bi, Wenwen Chen, Wei Zhang, Yi Shi, Lei Zhao, Xiaoman Sun, Fei Wang, Shuihong Cheng, Jinghua Yan, Wenjun Liu, Xingyu Jiang, George F Gao, Xuebing Li*. Analysis of Influenza Virus Receptor Specificity Using Glycan-Functionalized Gold Nanoparticles. ACS nano 2014, 8(5), 4600–4607. Shuihong Cheng, Huiqin Zhao, Yaozu Xu, Yawei Yang, Xun Lv, Peixing Wu, Xuebing Li*. Inhibition of influenza virus infection with chitosan–sialyloligosaccharides ionic complex. Carbohydrate Polymers 2014, 107, 132-137. Jinhua Wei, Xun Lv, Yang Lü, Gangzhu Yang, Lifeng Fu, Liu Yang, Jianjun Wang, Jianhui Gao, Shuihong Cheng, Qian Duan, Cheng Jin, Xuebing Li*. Glycosynthase with Broad Substrate Specificity an Efficient Biocatalyst for the Construction of Oligosaccharide Library. European Journal of Organic Chemistry 2013, 12, 2414-2419. Changgeng Li, Zhenxing Zhang, Qian Duan, and Xuebing Li*. Glycopeptide Synthesis on an Ionic Liquid Support. Organic Letters 2014, 16(11), 3008-3011. Xuebing Li*, Peixing Wu, Shuihong Cheng, and Xun Lv. Synthesis and assessment of globotriose-chitosan conjugate – a novel inhibitor of Shiga toxins produced by Escherichia coli. Journal of Medicinal Chemistry 2012, 55, 2702?2710. Yongmeng Li, Yan Zhou, Yufang Ma, Xuebing Li*. Design and synthesis of novel cell wall inhibitors of Mycobacterium tuberculosis GlmM and GlmU. Carbohydrate Research 2011, 346, 1714–1720. Xuebing Li*, Peixing Wu, George F. Gao, and Shuihong Cheng. Carbohydrate- functionalized chitosan fiber for influenza virus capture. Biomacromolecules 2011, 12, 3962–3969. Jing Han and Xuebing Li*. Chemoenzymatic syntheses of sialyl Lewis X-chitosan conjugate as potential anti-inflammatory agent. Carbohydrate Polymers 2011, 83, 137–143. Yaozu Xu, Hongjie Fan, Chengping Lu, George F. Gao, and Xuebing Li*. Synthesis of galabiose-chitosan conjugate as potent inhibitor of Streptococcus suis adhesion. Biomacromolecules 2010, 11, 1701–1704. Xuebing Li, Masato. Ogawa Toshiki Monden, Takahiro Maeda, Eri Yamashita, Mariko Naka, Masao Matsuda, Hiroshi Hinou, Shin-Ichiro Nishimura*. Glycosidation promoted by a reusable solid superacid in supercritical carbon dioxide, Angewandte Chemie International Edition 2006, 45, 5652-5655.

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