Ritter, Tobias - Harvard University - Department of Chemistry and Chemical Biology

个人简介

Tobias Ritter was appointed as Assistant Professor in the Department of Chemistry and Chemical Biology at Harvard in 2006 and promoted to Associate Professor in 2010. His research program is based on synthetic organic and organometallic chemistry with a focus on catalysis. The Ritter lab currently engages in the development of fluorination chemistry for late-stage functionalization of complex natural and unnatural products. Ritter studied in Braunschweig, Germany, Lausanne, Switzerland, Bordeaux, France, and Stanford, US. He performed undergraduate research with Prof. Barry M. Trost at Stanford, obtained his PhD working with Prof. Erick M. Carreira at ETH Zurich in 2004, and was a postdoc with Prof. Robert H. Grubbs at Caltech.

研究领域

Catalysis Inorganic Organic Organometallics

近期论文

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H. Shi, D. Babinski, T. Ritter "Modular C–H Functionalization Cascade of Aryl Iodides" J. Am. Chem. Soc. 2015, ASAP. C. Neumann, T. Ritter. "Late-Stage Fluorination: Fancy Novelty or Useful Tool?" Angew. Chem. Int. Ed. 2015, 54, 3216. F. Sladojevich, E. McNeill, J. Boergel, S.-L. Zheng, T. Ritter. "Condensed-Phase, Halogen-Bonded CF3I and C2F5I Adducts for Perfluoroalkylation Reactions" Angew. Chem. Int. Ed. 2015 ASAP. T. Fujimoto, T. Ritter. "PhenoFluorMix: Practical Chemoselective Deoxyfluorination of Phenols" Org.Lett. 2015, 17, 544. M. Campbell, T. Ritter. "Modern Carbon-Fluorine Bond Forming Reactions for Aryl-Fluoride Synthesis" Chem. Rev. 2015, 115, 612. T. Fujimoto, F. Becker, T. Ritter. "PhenoFluor: Practical Synthesis, New Formulation, and Deoxyfluorination of Heteroaromatics" Org. Proc. Res. Develop. 2014, 18, 1041. H. Ren, H.-Y. Wey, M. Strebl, R. Neelamegam, T. Ritter, J. Hooker. "Synthesis and Imaging Validation of [18F]MDL100907 Enabled by Ni-Mediated Fluorination " ACS Chem. Neurosci. 2014, 5, 611. S. Parker, J. Boergel, T. Ritter. "1,2-Selective Hydrosilylation of Conjugated Dienes" J. Am. Chem. Soc. 2014, 136, 4857. M. Campbell, T. Ritter. "Late-Stage Fluorination: From Fundamentals to Application" Org. Proc. Res. Develop. 2014, 18, 474. E. Regalado, M. Kozlowski,J. Curto, T. Ritter, M. Campbell, A. Mazzotti, B. Hamper, C. Spilling, M. Mannino, L. Wan, J.-Q. Yu, J. Liu, C. Welch. "Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry" Org. Biomol. Chem. 2014, 12, 2161. D.C. Powers, T. Ritter. "Oxidation of Carbon-Metal Bonds" Comprehensive Organic Synthesis II 2014, chapter 7.27. T. Liang, T. Ritter. "Synthesis of Fluorides" Comprehensive Organic Synthesis II 2014, chapter 6.07. K. P. Kornecki, J.F. Berry, D.C. Powers, T. Ritter. "Metal-metal bond-containing complexes as catalysts for C-H functionalization" Prog. Inorg. Chem. 2014, 58, 223-300. J. R. Brandt, E. Lee, G. Boursalian, T. Ritter. "Mechanism of Electrophilic Fluorination with Pd(IV): Fluoride Capture and Subsequent Oxidative Fluoride Transfer" Chem. Sci 2014, 5, 169-179. A. Mazzotti, M. Campbell, P. Tang, J. Murphy, T. Ritter. "Palladium(III)-catalyzed Fluorination of Arylboronic Acid Derivatives" J. Am. Chem. Soc. 2013, 135, 14012-14015. M. Campbell, S.-L. Zheng, T. Ritter. "One-Dimensional Palladium Wires: Influence of Molecular Changes on Supramolecular Structure" Inorg. Chem. 2013, 52, 13295–13297. G. Boursalian, M. Ngai, K. Hojczyk, T. Ritter. "Pd-Catalyzed Aryl C-H Imidation with Arene as the Limiting Reagent" J. Am. Chem. Soc. 2013, 135, 13278-13281. T. Liang, C. Neumann, T. Ritter. "Introduction of Fluorine and Fluorine-Containing Functional Groups" Angew. Chem. Int. Ed. 2013, 52, 8214-8264. D. Powers, T. Ritter. "A Transition State Analogue for the Oxidation of Binuclear Palladium(II) to Binuclear Palladium(III) Complexes" Organometallics 2013, 32, 2042-2045. A. Kamlet, C. Neumann, E. Lee, S. Carlin, C. Moseley, N. Stephenson, J. Hooker, T. Ritter. "Application of Palladium-Mediated 18F-Fluorination to PET Radiotracer Development: Overcoming Hurdles to Translation" PLOS one 2013, 8, e59187. F. Sladojevich, S. Arlow, P. Tang, T. Ritter. "Late-Stage Deoxyfluorination of Alcohols with Phenofluor" J. Am. Chem. Soc. 2013, 135, 2470–2473.