董晓燕 - 天津大学

个人简介

Education： B.Sc. –1982, Department of Biochemistry, Qinghai Institute of Veterinary Medicine, Xining, China M.Sc. – 1990, Graduate School of Agriculture, Shinshu University, Nagano, Japan Dr. Eng. – 2005, Department of Biochem. Eng., Tianjin University, Tianjin, China Professional Activities： 1982 – 1986 Research Associate, Qinghai Academy of Veterinary Medicine 1986 – 1987 Research Fellow, Tokyo Institute of Agriculture and Technology 1990 – 1991 Research Fellow, High Separation Center, Soken Chem Eng Co, Tokyo 1991 – 1996 Lecturer, Department of Biochemical Engineering, TJU 1995 – 1996 Visiting Scientist, Faculty of Agriculture, Kyushu University, Japan 1996 – 2002 Associate Professor, Department of Biochemical Engineering, TJU 2002 – present Professor, Department of Biochemical Engineering, TJU 学术成就: 1，2002年中国高校自然科学奖二等奖（排名第2） 2，2004年天津市自然科学一等奖（排名第2） 3，2012年教育部自然科学二等奖（排名第3） 4，2011年教育部普通高等教育精品教材（《生物化学》董晓燕主编）

研究领域

1，生物大分子的结构与功能、蛋白质折叠 2，生物大分子的分离纯化 3，基因工程

近期论文

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J Gao#, J-F Wang#, R-R Guo#, Y Hu, X-Y Dong, Q-H Shi, Y Sun*: Efficient cascade conversion of starch to gluconic acid by a chemoenzymatic system with co-immobilized Au nanoparticles and enzymes. Catalysis Science and Technology, 2023, 13: 991-999. Z-F Wang#, J Gao#, Q-H Shi#, X-Y Dong*, Y Sun: Facile purification and immobilization of organophosphorus hydrolase on protein-inorganic hybrid phosphate nanosheets. Chinese Journal of Chemical Engineering, 2023, 56： 119-125. X-Q Chen, W-Q Gao, Y Sun, X-Y Dong*: Multiple effects of polydopamine nanoparticles on Cu2+-mediated Alzheimer's β-amyloid aggregation. Chinese Journal of Chemical Engineering, 2023, 54： 144-152. X-D Lin, W Liu, X-Y Dong, Y Sun*: Epigallocatechin gallate-derived carbonized polymer dots: A multifunctional scavenger targeting Alzheimer's β-amyloid plaques. Acta Biomaterialia, 2023, 157： 524-537. M-M Liu, W-J Wang, X-P Hao, X-Y Dong*: Seeding and Cross-seeding Aggregations of Aβ40 and hIAPP in Solution and on Surface. Acta Physico-Chimica Sinica, 2022, 38 (3): 2002024. W Liu#, X-T Sun#, X-Y Dong, Y Sun*: Chiral LVFFARK enantioselectively inhibits amyloid-β protein fibrillogenesis. Chinese Journal of Chemical Engineering, 2022, 48: 227-235. W-J Wang, X-Y Dong, Y Sun*: A multi-target theranostic nano-composite against Alzheimer's disease fabricated by conjugating carbon dots and triple-functionalized human serum albumin. Acta Biomaterialia, 2022, 148: 298-309. S Liu, Z-F Wang, K Chen, Q-H Shi, X-Y Dong, Y Sun*: Cascade chiral amine synthesis catalyzed by site-specifically co-immobilized alcohol and amine dehydrogenases. Catalysis Science and Technology, 2022, 12： 4486-4497. K Chen, X-Y Dong, Y Sun*: Sequentially co-immobilized PET and MHET hydrolases via Spy chemistry in calcium phosphate nanocrystals present high-performance PET degradation. Journal of Hazardous Materials, 2022, 438, 129517. C-Y Zhang, Y Sun, X-Y Dong*: Conjugation of a zwitterionic polymer with dimethyl chains to lipase significantly increases the enzyme activity and stability. Chinese Journal of Chemical Engineering, 2022, 47, 48−53. X-Q Wang#, Z-F Wang#, L-L Yu, Q-H Shi, X-Y Dong, Y Sun*: Zwitterionic polymer-mediated immobilization of organophosphorus hydrolase enhances hydrolysis of methyl parathion by substrate enrichment. Biochemical Engineering Journal, 2022, 184: 108491. Y Liang#, W-J Wang#, Y Sun, X-Y Dong*: Insights into the cross-amyloid aggregation of Aβ40 and its N-terminal truncated peptide Aβ11-40 affected by epigallocatechin gallate. Chinese Journal of Chemical Engineering, 2022, 45: 284-293. W Liu#, H Zhang#, X-Y Dong, Y Sun*: Composite of gold nanoclusters and basified human serum albumin significantly boosts the inhibition of Alzheimer's β-amyloid by photo-oxygenation. Acta Biomaterialia, 2022, 144: 157-167. X-S Chu, X-H Yang, Q-H Shi*, X-Y Dong, Y Sun: Kinetic and molecular insight into immunoglobulin G binding to immobilized recombinant protein A of different orientations. Journal of Chromatography A, 2022, 1671: 463040. S-Y Xu, Y Sun, X-Y Dong*: Design of gallic acid-glutamine conjugate and chemical implications for its potency against Alzheimer's amyloid-β fibrillogenesis. Bioconjugate Chemistry, 2022, 33, 677−690.

学术兼职

美国化学工程师协会（AIChE）高级会员；美国化学学会（ACS）会员