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个人简介

EDUCATION 1996 PhD, Institute of Elemento-organic Chemistry, Nankai University 1990 BS, Nankai University ACADEMIC CAREER 2004-Date Professor, Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University 2001-2004 Postdoctoral, University of Kentucky, USA 1999-2001 Postdoctoral, Nagoya University, Japan

研究领域

Polycyclic skeletons construction-oriented synthetic methodology, Natural products synthesis, Leads discovery

近期论文

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Chi Zhang, Jun Tian, Jun Ren, Zhongwen Wang* “Intramolecular Parallel [4 + 3] Cycloadditions of Cyclopropane 1,1-Diesters with [3]Dendralenes: Efficient Construction of [5.3.0]decane and Corresponding Polycyclic Skeletons” Chem. Eur. J. 2016, Published as “Frontispiece” (DOI: 10.1002/chem.201605190). Zhenjun Wang, Shuai Chen, Jun Ren, Zhongwen Wang* “Cooperative Photo-/Lewis Acid Catalyzed Tandem Intramolecular [3+2] Cross-Cycloadditions of Cyclopropane 1,1-Diesters with α , β -Unsaturated Carbonyls for Medium-Sized Carbocycles” Org. Lett. 2015, 17, 4184-4187. Weiwei Ma, Jie Fang, Jun Ren, Zhongwen Wang* “Lewis Acid Catalyzed Formal Intramolecular [3+3] Cross-Cycloaddition of Cyclopropane 1,1-Diesters for Construction of Benzobicyclo[2.2.2]octane Skeletons” Org. Lett. 2015, 17, 4180-4183. Lewis acid catalyzed intramolecular [3+2] cross cycloadditions of cobalt-alkynylcyclopropane 1,1-diesters with carbonyl for construction of medium-sized and polycyclic skeletons,J. Zhang, S. Xing, J. Ren, S. Jiang, Z.Wang, Org. Lett. 2015,17, 218-221. Lewis acid catalyzed intramolecular [3+2] cross cycloadditions of cobalt-alkynylcyclopropane 1,1-diesters with carbonyl for construction of medium-sized and polycyclic skeletons, Junhui Zhang, Siyang Xing, Jun Ren, Shende Jiang*, Zhongwen Wang* Org. Lett. 2015, 17, 218-221. Bo Cui, Jun Ren, Zhongwen Wang* “TfOH-catalyzed Formal [3+2] Cycloaddition of Cyclopropane 1,1- Diesters with Nitriles” J. Org. Chem. 2014, 79, 790-796. Wenju Zhu, Jie Fang, Yong Liu, Jun Ren, Zhongwen Wang* “Lewis Acid Catalyzed Formal Intramolecular [3+2] Cross-Cycloaddition of Cyclopropane 1,1-Diesters with Alkenes: General and Efficient Strategy for Construction of Bridged [n.2.1] Carbocyclic Skeletons” Angew. Chem. Int. Ed. 2013, 52, 2032-2037. Zhenjun Wang, Jun Ren, Zhongwen Wang* “Lewis Acids Promoted Formal Intramolecular [3+2] Parallel and Cross-Cycloadditions of Cyclopropane 1,1-Diesters with Allenes” Org. Lett. 2013, 15, 5682-5685. Yu Bai, Weijie Tao, Jun Ren, Zhongwen Wang* “Lewis Acid Catalyzed Intramolecular [4+2] and [3+2] Cross-Cycloaddition of Alkynylcyclopropane Ketones with Carbonyl Compounds and Imines” Angew. Chem. Int. Ed. 2012, 51, 4112-4116. Zhongwen Wang* “Polar Intramolecular Cross-Cycloadditions of Cyclopropanes toward Natural Product Synthesis” Synlett 2012, 23, 2311-2327 (Account). Siyang Xing, Yan Li, Zhen Li, Chang Liu, Jun Ren, Zhongwen Wang* “Lewis Acid-Catalyzed Intramolecular Cross [3+2] Cycloaddition of Donor-Acceptor Cyclopropanes with Carbonyls: A General Strategy for Construction of Bridge-Acetal[n.2.1] Skeletons” Angew. Chem. Int. Ed. 2011, 50, 12605-12609. Linxia Li, Ding Du, Jun Ren, Zhongwen Wang* “N-Heterocyclic Carbene Catalyzed Domino Reactions of Formylcyclopropane 1,1-Diesters: Construction of a 6-5-5 Tricyclic Pyrrolo[1,2-a]indole” Eur. J. Org.Chem.2011, 614-618. Siyang Xing, Wenyan Pan, Chang Liu, Jun Ren, Zhongwen Wang* “Efficient Construction of Oxa- and Aza-[n.2.1] Skeletons: Lewis Acid-Catalyzed Intramolecular [3+2] Cycloaddition of Cyclopropane 1,1- Diesters with Carbonyls and Imines” Angew. Chem. Int. Ed. 2010, 49, 3215-3218 Bao Hu, Siyang Xing, Jun Ren, Zhongwen Wang* “Total Synthesis of (±)-Bruguierol A via an Intramolecular [3+2] Cycloaddition of Cyclopropane 1,1-Diester” Tetrahedron, 2010, 66, 5671-5674. Bai Yu, Jie Fang, Jun Ren, Zhongwen Wang* “Highly Diastereoselective Gold- or Copper-Catalyzed Formal [4+3] Cycloaddition of 1-(1-Alkynyl) Cyclopropyl Ketones and Nitrones” Chem. Eur. J. 2009, 15, 8975-8978. Ding Du, Linxia Li, Zhongwen Wang* “N-Heterocyclic Carbene-Catalyzed Domino Ring-Opening/Redox Amidation/Cyclization Reactions of Formylcyclopropane 1,1-Diesters: Direct Construction of a 6-5-6 Tricyclic Hydropyrido[1,2-a]indole Skeleton” J. Org. Chem. 2009, 74, 4379-4382. Bao Hu, Jianlin Zhu, Siyang Xing, Jie Fang, Ding Du, Zhongwen Wang* “A Highly Site-, Regio-, and Stereoselective Lewis Acid-Catalyzed Formal [3+3] Cycloaddition of Methylenecyclopropane-1,1-Diesters with C,N-Diarylnitrones” Chem. Eur. J. 2009, 15, 324-327. Yuexia Bai, Jilai Bao, Jun Ren, Zhongwen Wang* “A modified total synthesis of cystothiazole A” Sci. China Ser. B-Chem 2009, 52, 1345-1352. Bao Hu, Siyang Xing, Zhongwen Wang* “Lewis Acid Catalyzed Ring-Opening Intramolecular Friedel-Crafts Alkylation of Methylenecyclopropane 1,1-Diesters” Org. Lett. 2008, 10, 5481-5484. Jie Fang, Jun Ren, Zhongwen Wang* “Sc(OTf)3-catalyzed smooth tandem [3+2] cycloaddition/ring opening of donor–acceptor cyclopropane 1,1-diesters with enol silyl ethers” Tetrahedron Lett. 2008, 49, 6659-6662. Ding Du, Zhongwen Wang* “N-Heterocyclic Carbene-Catalyzed Domino Reactions of Formylcyclopropane 1,1-Diesters: A New Synthesis of Coumarins” Eur. J. Org. Chem. 2008, 4949-4954.

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