样式: 排序: IF: - GO 导出 标记为已读
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TRIM47-CDO1 axis dictates hepatocellular carcinoma progression by modulating ferroptotic cell death through the ubiquitin‒proteasome system Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-16 Jie Zhang, Malire Yimamu, Ziqi Cheng, Jie Ji, Liwei Wu, Jiao Feng, Xuanfu Xu, Jianye Wu, Chuanyong Guo
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TXNIP knockdown protects rats against bupivacaine-induced spinal neurotoxicity via the inhibition of oxidative stress and apoptosis Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-14 Yang Zhao, Yuanyuan Chen, Ziru Liu, Lei Zhou, Jiao Huang, Xi Luo, Yunpeng Luo, Jia Li, Yunan Lin, Jian Lai, Jingchen Liu
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SP2509 functions as a novel ferroptosis inhibitor by reducing intracellular iron level in vascular smooth muscle cells Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-10 Yi He, Xingbo Wang, Siqi Chen, Hanshen Luo, Bo Huo, Xian Guo, Rui Li, Yue Chen, Xin Yi, Xiang Wei, Ding-Sheng Jiang
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Itaconate as a key player in cardiovascular immunometabolism Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-10 Wenju Shan, Jun Cui, Yujie Song, Dongxu Yan, Linqi Feng, Yuhong Jian, Wei Yi, Yang Sun
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Effect of a personalized intensive dietary intervention on base excision repair (BER) in colorectal cancer patients: Results from a randomized controlled trial Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-06 Anne Lene Nordengen, Congying Zheng, Annika Krutto, Ane S. Kværner, Dena T. Alavi, Hege B. Henriksen, Christine Henriksen, Sigbjørn Smeland, Siv K. Bøhn, Ingvild Paur, Sergey Shaposhnikov, Andrew R. Collins, Rune Blomhoff
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Activation of lipophagy is required for RAB7 to regulate ferroptosis in sepsis-induced acute kidney injury Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-05 Yuanting Yang, Qisheng Lin, Xuying Zhu, Xinghua Shao, Shu Li, Jialin Li, Jingkui Wu, Haijiao Jin, Chaojun Qi, Na Jiang, Kaiqi Zhang, Qin Wang, Leyi Gu, Zhaohui Ni
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Doxorubicin induces phosphorylation of lamin A/C and loss of nuclear membrane integrity: A novel mechanism of cardiotoxicity Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-05 Vikas Tiwari, Paras Gupta, Navya Malladi, Sanjay Salgar, Sanjay K. Banerjee
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Mitochondrial quality control in non-exudative age-related macular degeneration: From molecular mechanisms to structural and functional recovery Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-04 Hernán H. Dieguez, Horacio E. Romeo, Agustina Alaimo, Nathaly A. Bernal Aguirre, Juan S. Calanni, Juan S. Adán Aréan, Silvia Alvarez, Roberta Sciurano, Ruth E. Rosenstein, Damián Dorfman
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Corrigendum to “AMPK/PGC1α activation by melatonin attenuates acute doxorubicin cardiotoxicity via alleviating mitochondrial oxidative damage and apoptosis” [Free Radic. Biol. Med. 129 (2018) 59–72] Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-04 Dong Liu, Zhiqiang Ma, Shouyin Di, Yang Yang, Jingang Yang, Liqun Xu, Russel J. Reiter, Shubin Qiao, Jiansong Yuan
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TET3 boosts hepatocyte autophagy and impairs non-alcoholic fatty liver disease by increasing ENPP1 promoter hypomethylation Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-04 Feng Sun, Yang Yang, Lin Jia, Qi-Qi Dong, Wei Hu, Hui Tao, Chao Lu, Jing-Jing Yang
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Peroxiredoxin 6 suppresses ferroptosis in lung endothelial cells Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-03 Julia María Torres-Velarde, Kaitlin N. Allen, Andrea Salvador-Pascual, Roberto G. Leija, Diamond Luong, Diana Daniela Moreno-Santillán, David C. Ensminger, José Pablo Vázquez-Medina
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Feasibility study of multimodal imaging for redox status and glucose metabolism in tumor Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-03 Kazuhiro Kato, Hironobu Yasui, Hideo Sato-Akaba, Miho C. Emoto, Hirotada G. Fujii, Maciej M. Kmiec, Periannan Kuppusamy, Yuki Mizuno, Yuji Kuge, Masaki Nagane, Tadashi Yamashita, Osamu Inanami
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Mitochondrial remodeling underlying age-induced skeletal muscle wasting: let’s talk about sex Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-02 Alexandra Moreira-Pais, Rui Vitorino, Cláudia Sousa-Mendes, Maria João Neuparth, Alessandro Nuccio, Claudio Luparello, Alessandro Attanzio, Petr Novák, Dmitry Loginov, Rita Nogueira-Ferreira, Adelino Leite-Moreira, Paula A. Oliveira, Rita Ferreira, José A. Duarte
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Quantifying redox transcription factor dynamics as a tool to investigate redox signalling Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-02 Diane J. Lind, Kelisa C. Naidoo, Lewis E. Tomalin, Johann M. Rohwer, Elizabeth A. Veal, Ché S. Pillay
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Downregulated GPX4 in salivary gland epithelial cells contributes to salivary secretion dysfunction in Sjogren's syndrome via lipid ROS/pSTAT4/AQP5 axis Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-02 Jiannan Zhou, Janak L. Pathak, Lihong Wu, Bo Chen, Tingting Cao, Wei Wei, Xiaodan Wu, Guiping Chen, Nobumoto Watanabe, Xiaomeng Li, Jiang Li
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Unlocking the anticancer activity of gambogic acid: a shift towards ferroptosis via a GSH/Trx dual antioxidant system Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-02 Jinshuai Lan, Li Liu, Wenjun Zhao, Zhe Li, Ruifeng Zeng, Shiyuan Fang, Lixia Chen, Yi Shen, Hai Wei, Tong Zhang, Yue Ding
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Mapping the interplay of immunoproteasome and autophagy in different heart failure phenotypes Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-04-01 Christiane Ott
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From powerhouse to regulator: The role of mitoepigenetics in mitochondrion-related cellular functions and human diseases Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-31 Luigi Donato, Domenico Mordà, Concetta Scimone, Simona Alibrandi, Rosalia D'Angelo, Antonina Sidoti
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FRBM Mini REVIEW: Chemogenetic approaches to probe redox dysregulation in heart failure Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-31 Ruby Guo, Fotios Spyropoulos, Thomas Michel
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Knockdown of RGMA improves ischemic stroke via Reprogramming of Neuronal Metabolism Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-30 Zijie Wang, Shaoru Zhang, Ruiqi Cheng, Anan Jiang, Xinyue Qin
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Hydrogen alleviates impaired lung epithelial barrier in acute respiratory distress syndrome via inhibiting Drp1-mediated mitochondrial fission through the Trx1 pathway Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-28 Yun Long, Yang Ang, Wei Chen, Yujie Wang, Min Shi, Fan Hu, Qingqing Zhou, Yadan Shi, Baokui Ge, Yigen Peng, Wanyou Yu, Hongguang Bao, Qian Li, Manlin Duan, Ju Gao
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Intermittent fasting improves the oocyte quality of obese mice through the regulation of maternal mRNA storage and translation by LSM14B Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-27 Chan Li, Hui Zhang, Hao Wu, Jingmei Li, Qingyang Liu, Yanxue Li, Menghao Pan, Xiaoe Zhao, Qiang Wei, Sha Peng, Baohua Ma
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Mitochondria-tau association promotes cognitive decline and hippocampal bioenergetic deficits during the aging Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-27 Margrethe A. Olesen, Eugenia Pradenas, Francisca Villavicencio-Tejo, George A. Porter, Gail V.W. Johnson, Rodrigo A. Quintanilla
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Edaravone dexborneol protects against cerebral ischemia/reperfusion-induced blood-brain barrier damage by inhibiting ferroptosis via activation of nrf-2/HO-1/GPX4 signaling Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-26 Peng Xiao, Haiyan Huang, Hanshu Zhao, Ruijia Liu, Zhiyu Sun, Yushuang Liu, Nan Chen, Zhongling Zhang
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Edaravone counteracts redox and metabolic disruptions in an emerging zebrafish model of sporadic ALS Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-24 Nuno A.S. Oliveira, Brígida R. Pinho, Joana Pinto, Paula Guedes de Pinho, Jorge M.A. Oliveira
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Derlin-1 promotes diet-induced non-alcoholic fatty liver disease via increasing RIPK3-mediated necroptosis Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-24 Ting Wang, Dehua Wang, Ge Kuang, Xia Gong, Li Zhang, Jingyuan Wan, Ke Li
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MLL1 histone methyltransferase and UTX histone demethylase functionally cooperate to regulate the expression of NRF2 in response to ROS-induced oxidative stress Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-23 Janghyun Choi, Hansol Lee
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Cryptochrome 1 regulates ovarian granulosa cell senescence through NCOA4-mediated ferritinophagy Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-22 Jing Ma, Sixing Chen, Jing Liu, Yixin Liao, Lina Li, Chi Chiu Wang, Sishi Song, Rixuan Feng, Haoyue Hu, Song Quan
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Activation of mitoKATP channels induces penile vasodilation and inhibits mitochondrial respiration and ROS production: Role of NO Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-22 Alfonso Gómez del Val, Cristina Contreras, Mercedes Muñoz, Javier Sáenz-Medina, Mariam Mohamed, Luis Rivera, Ana Sánchez, Dolores Prieto
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Modern optical approaches in redox biology: Genetically encoded sensors and Raman spectroscopy Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-18 Alexander I. Kostyuk, Diana D. Rapota, Kseniia I. Morozova, Anna A. Fedotova, David Jappy, Alexey V. Semyanov, Vsevolod V. Belousov, Nadezda A. Brazhe, Dmitry S. Bilan
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Corrigendum to “Activation of TGR5 with INT-777 attenuates oxidative stress and neuronal apoptosis via cAMP/PKCε/ALDH2 pathway after subarachnoid hemorrhage in rats” [Free Radic. Biol. Med. (2019 Nov 1) 143 441–453] Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-18 Gang Zuo, Tongyu Zhang, Lei Huang, Camila Araujo, Jun Peng, Zachary Travis, Takeshi Okadab, Umut Ocak, Guangyu Zhang, Jiping Tang, Xiaojun Lu, John H. Zhang
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mtDNA regulates cGAS-STING signaling pathway in adenomyosis Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-15 Kun Wang, Yi Wen, Xianyun Fu, Shaobin Wei, Shidan Liu, Minmin Chen
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TIGAR reduces neuronal ferroptosis by inhibiting succinate dehydrogenase activity in cerebral ischemia Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-15 Xinxin Wang, Mei Li, Fan Wang, Guanghui Mao, Junchao Wu, Rong Han, Rui Sheng, Zhenghong Qin, Hong Ni
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Are age-related neurodegenerative diseases caused by a lack of the diet-derived compound ergothioneine? Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-14 Barry Halliwell, Irwin Cheah
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Redox organization of living systems Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-14 Dean P. Jones
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Corrigendum to “Effects of dietary inorganic nitrate on blood pressure during and post-exercise recovery: A systematic review and meta-analysis of randomized placebo-controlled trials” [Free Radic. Biol. Med. (2024) 215 25–36] Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-13 Cicero Jonas R. Benjamim, Leonardo S. Lopes da Silva, Vitor E. Valenti, Leonardo S. Gonçalves, Andrey A. Porto, Márcio Fernando Tasinafo Júnior, Jean-Philippe Walhin, David M. Garner, Bruno Gualano, Carlos R. Bueno Júnior
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Neuroprotective effects of cordycepin on MPTP-induced Parkinson's disease mice via suppressing PI3K/AKT/mTOR and MAPK-mediated neuroinflammation Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-12 Linhai Wang, Shu Tian, Sisi Ruan, Jingjing Wei, Sijia Wei, Weiwei Chen, Hangcui Hu, Weiwei Qin, Yan Li, Hang Yuan, Jian Mao, Yan Xu, Jianping Xie
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Hydrogen sulfide improves endothelial barrier function by modulating the ubiquitination degradation of KLF4 through TRAF7 S-sulfhydration in diabetic aorta Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-12 Qianzhu Li, Jiaxin Kang, Ning Liu, Jiayi Huang, Xueya Zhang, Kemiao Pang, Shiwu Zhang, Mengyi Wang, Yajun Zhao, Shiyun Dong, Hongxia Li, Dechao Zhao, Fanghao Lu, Weihua Zhang
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Changed regulation of granulocyte NADPH oxidase activity in the mouse model of obesity-induced type 2 diabetes mellitus Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-11 Irina V. Tikhonova, Alsu R. Dyukina, Andrei A. Grinevich, Elvira R. Shaykhutdinova, Valentina G. Safronova
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Reactive oxygen species augment contractile responses of saphenous artery in 10-15-day-old but not adult rats: Substantial role of NADPH oxidases Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-08 Anastasia A. Shvetsova, Margarita A. Khlystova, Yulia A. Makukha, Valentina S. Shateeva, Anna A. Borzykh, Dina K. Gaynullina, Olga S. Tarasova
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The long coiled-coil protein NECC2 regulates oxLDL-induced endothelial oxidative damage and exacerbates atherosclerosis development in apolipoprotein E −/− mice Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-08 Xin Mu, Shu-Jun Liu, Lei-Yin Zheng, Chenxi Ouyang, Ahmed M.E. Abdalla, Xin-Xin Wang, Kai Chen, Fei-Fei Yang, Ning Meng
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Unveiling the antioxidant superiority of α-tocopherol: Implications for vitamin E nomenclature and classification Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-07 Hao Tian, Yi-Fang Li, Gen-Long Jiao, Wan-Yang Sun, Rong-Rong He
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Glsirt1-mediated deacetylation of GlCAT regulates intracellular ROS levels, affecting ganoderic acid biosynthesis in Ganoderma lucidum Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-07 Jing Han, Lingshuai Wang, Xin Tang, Rui Liu, Liang Shi, Jing Zhu, Mingwen Zhao
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Chronic exposure to PM10 induces anxiety-like behavior via exacerbating hippocampal oxidative stress Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-06 Jie Cheng, Jian Sun, Rui Niu, Xiaoqing Wang, Guilin Hu, Fan Li, Kunrong Gu, Hao Wu, Yuanchun Pu, Fanqi Shen, Hao Hu, Zhenxing Shen
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Hydrogen exerts neuroprotective effects after subarachnoid hemorrhage by attenuating neuronal ferroptosis and inhibiting neuroinflammation Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-04 Zheng Peng, Xiao-Jian Li, Yan Zhou, Jia-Tong Zhang, Qi Zhu, Jia-Qing Sun, Chun-Hua Hang, Wei Li, Qing-Rong Zhang, Zong Zhuang
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Cardiac Resolvin D2 ameliorates sepsis-induced cardiomyopathy via inhibiting Caspase-11/GSDMD dependent pyroptosis Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-02 Wen-wu Zhang, Shun-shun Wang, Yang-dong Ding, Xin-yi Wu, Ting Chen, Ye Gao, Sheng-wei Jin, Pu-hong Zhang
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Revising the nomenclature for vitamin E requires agreement on its vitamin function Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-01 Alexander Montoya-Arroyo, Jan Frank
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Overexpression of cat2 restores antioxidant properties and production traits in degenerated strains of Volvariella volvacea Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-03-01 Jianing Zhu, Wenpei Wang, Wanhe Sun, Yuanxi Lei, Qiangfei Tan, Gahong Zhao, Jianmin Yun, Fengyun Zhao
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Redox-associated changes in healthy individuals at risk of Alzheimer's disease. A ten-year follow-up study Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-02-27 Mariana Nepomuceno, Paloma Monllor, Maria Jose Cardells, Artemis Ftara, Maria Magallon, Francisco Dasí, Mari Carmen Badia, Jose Viña, Ana Lloret
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Corrigendum to “Clozapine-N-oxide protects dopaminergic neurons against rotenone-induced neurotoxicity by preventing ferritinophagy-mediated ferroptosis” [Free Radic. Biol. Med. 212 (2024) 384–402] Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-02-25 Qingquan Sun, Yan Wang, Liyan Hou, Sheng Li, Jau-Shyong Hong, Qingshan Wang, Jie Zhao
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Allogeneic platelet-rich plasma inhibits ferroptosis in promoting wound repair of type 2 diabetic ulcers Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-02-24 Danlian Zhou, Qiu Liang, Xiuyu Ge, Jing Xu
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Vitamin E: Not only a single stereoisomer Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-02-23 M. Eggersdorfer, K. Schmidt, S. Péter, J. Richards, B. Winklhofer-Roob, A. Hahn, U. Obermüller-Jevic
The recent publication by Azzi and colleagues puts forth the argument that only -α-tocopherol should be considered as vitamin E from a physiological point of view. They base their argument primarily on the assertion that only this form has been used to treat stark vitamin E deficiency in humans (known as AVED, or Ataxia with Vitamin E Deficiency). Azzi et al. also argue that other chemically similar
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Effects of dietary inorganic nitrate on blood pressure during and post-exercise recovery: A systematic review and meta-analysis of randomized placebo-controlled trials Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-02-23 Cicero Jonas R. Benjamim, Leonardo S. Lopes da Silva, Vitor E. Valenti, Leonardo S. Gonçalves, Andrey A. Porto, Márcio Fernando Tasinafo Júnior, Jean-Philippe Walhin, David M. Garner, Bruno Gualano, Carlos R. Bueno Júnior
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Systemic oxidative stress may be associated with reduced IgG antibody titers against SARS-CoV-2 in vaccinated kidney transplant recipients: A post-hoc analysis of the RECOVAC-IR observational study Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-02-22 Larissa E. van Eijk, Arno R. Bourgonje, A. Lianne Messchendorp, Marian L.C. Bulthuis, Marjan Reinders-Luinge, Berber Doornbos-van der Meer, Johanna Westra, Wilfred F.A. den Dunnen, Jan-Luuk Hillebrands, Jan-Stephan F. Sanders, Harry van Goor, RECOVAC Collaborators
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Therapeutic effect of mitochondrial transplantation on burn injury Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-02-22 Zhen Li, Xinhui Cao, Zuohao Liu, Fen Wu, Changjun Lin, Chun-Ming Wang
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Aging hallmarks, biomarkers, and clocks for personalized medicine: (re)positioning the limelight Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-02-21 M. Cristina Polidori
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Roles of ferroptosis in type 1 diabetes induced spermatogenic dysfunction Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-02-17 Yalei Cao, Zirun Jin, Yu Xi, Jianxing Cheng, Zishui Fang, Qiancheng Zhao, Jiaming Weng, Jun Zhu, Yanlin Tang, Zhe Zhang, Hui Jiang
Diabetes mellitus (DM) is a widespread metabolic disease presenting with various complications, including spermatogenic dysfunction. However, the underlying mechanisms are still unclear. Ferroptosis, a novel type of programmed cell death, is associated with much metabolic diseases. Here, we investigated the role of ferroptosis in spermatogenic dysfunction of streptozotocin (STZ)-induced type 1 diabetic
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Corrigendum to “Drug screening identifies aldose reductase as a novel target for treating cisplatin-induced hearing loss” [Free Radic. Biol. Med. 210 (2024) 430–447] Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-02-17 Yaqi Liao, Huanyu Mao, Xian Gao, Hailiang Lin, Wenyan Li, Yan Chen, Huawei Li
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Single exposure to anesthesia/surgery in neonatal mice induces cognitive impairment in young adult mice Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-02-16 Songhua Zhou, Xiaoyu Cui, Jie Chen, Manli Luo, Wen Ouyang, Jianbin Tong, Zhongcong Xie, Yuan Le
The effects of a solitary neonatal exposure to anesthesia plus surgery (anesthesia/surgery) on cognitive function and the underlying mechanism in developing brains remains largely undetermined. We, therefore, set out to investigate the impact of single exposure to anesthesia/surgery in neonatal mice. Six-day-old male and female mice received abdominal surgery under 3% sevoflurane plus 50% oxygen for
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Benzoylaconitine: A promising ACE2-targeted agonist for enhancing cardiac function in heart failure Free Radical Bio. Med. (IF 7.4) Pub Date : 2024-02-16 Qi-qiang Zhang, Qing-shan Chen, Fei Feng, Xiang Cao, Xiao-fei Chen, Hai Zhang
Benzoylaconitine is a natural product in the treatment of cardiovascular disease. However, its pharmacological effect, direct target protein, and molecular mechanisms for the treatment of heart failure are unclear. In this study, benzoylaconitine inhibited Ang II-induced cell hypertrophy and fibrosis in rat primary cardiomyocytes and rat fibroblasts, while attenuating cardiac function and cardiac remodeling