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“We are a target”: scientific society under pressure after Trump DEI crackdown Nature (IF 50.5) Pub Date : 2025-02-07
The American Society for Microbiology deleted terms such as equity from its website, sparking protests from members.
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Have Trump’s anti-DEI orders hit private funders? HHMI halts inclusive science programme Nature (IF 50.5) Pub Date : 2025-02-07
The Howard Hughes Medical Institute, a huge funder of biomedical research, has cut a $60-million initiative to boost diversity in science education.
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DeepMind AI crushes tough maths problems on par with top human solvers Nature (IF 50.5) Pub Date : 2025-02-07
The company’s AlphaGeometry2 reaches the level of gold-medal students in the International Mathematical Olympiad.
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Poetry on Mars and robots on Earth: Books in brief Nature (IF 50.5) Pub Date : 2025-02-07
Andrew Robinson reviews five of the best science picks.
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Bonobos know when you’re in the know ― and when you’re not Nature (IF 50.5) Pub Date : 2025-02-07
The apes can tailor their communications to account for a human partner’s level of knowledge.
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From viral variants to devastating storms, how names shape the public's reaction to science Nature (IF 50.5) Pub Date : 2025-02-07
In episode 2 of 'What's in a name' we look at the how names can help scientists communicate with the public.
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Scientists globally are racing to save vital health databases taken down amid Trump chaos Nature (IF 50.5) Pub Date : 2025-02-07
The mass-archiving effort is in response to the US Centers for Disease Control and Prevention removing some of its web pages.
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How my research focus exposed me to threats and harassment Nature (IF 50.5) Pub Date : 2025-02-07
Researchers who investigate highly-politicized topics can face harassment, others for their race, gender identity or disability. Two scientists share their stories.
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Granzyme K activates the entire complement cascade Nature (IF 50.5) Pub Date : 2025-02-06 Carlos A. Donado, Erin Theisen, Fan Zhang, Aparna Nathan, Madison L. Fairfield, Karishma Vijay Rupani, Dominique Jones, Kellsey P. Johannes, Soumya Raychaudhuri, Daniel F. Dwyer, A. Helena Jonsson, Michael B. Brenner
Granzymes are a family of serine proteases mainly expressed by CD8+ T cells, natural killer cells, and innate-like lymphocytes1. Although their primary function is thought to be the induction of cell death in virally infected and tumor cells, accumulating evidence indicates certain granzymes can elicit inflammation by acting on extracellular substrates1. Recently, we found that the majority of tissue
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Mantis shrimp have the world’s fastest punch — here’s how their limbs survive Nature (IF 50.5) Pub Date : 2025-02-06
Insights from probing the shock-absorbing layer within the crustacean’s club-like claw could inspire the design of tough new materials.
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Record-setting trove of buried beads speaks to power of ancient women Nature (IF 50.5) Pub Date : 2025-02-06
A Copper Age burial in Spain holds the largest collection of beads ever found ― enough to require a tonne of shellfish as raw material.
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How to make the perfect egg: give it lukewarm baths Nature (IF 50.5) Pub Date : 2025-02-06
Process turns out eggs with delectable texture and high nutritional value.
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Daily briefing: Genetically modified pig-organ transplant trial gets green light Nature (IF 50.5) Pub Date : 2025-02-06
The first pig-organ transplant trial in humans has been approved. Plus, the internet doesn't affect our memories, but AI might.
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How the brain suppresses fear: mouse study offers path to anxiety treatments Nature (IF 50.5) Pub Date : 2025-02-06
Two brain regions work together when mice learn to override the instinct to run and hide from a potential threat.
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OpenAI’s ‘deep research’ tool: is it useful for scientists? Nature (IF 50.5) Pub Date : 2025-02-06
The model produces cited, pages-long reports that might be helpful for generating literature reviews.
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Engineered nose bacteria sneak drugs into the brain Nature (IF 50.5) Pub Date : 2025-02-06
Microbes that reside peaceably in the nasal passageways and on the skin can be harnessed for taking drugs to target cells.
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‘It is chaos’: US funding freezes are endangering global health Nature (IF 50.5) Pub Date : 2025-02-06
Abrupt changes to programmes including USAID inhibit global efforts to stop disease such as HIV, malaria and more, say researchers.
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The weight-loss drugs being tested in 2025: will they beat Ozempic? Nature (IF 50.5) Pub Date : 2025-02-06
Drug companies are trialling a host of medications that they hope will offer benefits beyond weight loss.
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AI Agents Under Threat: A Survey of Key Security Challenges and Future Pathways ACM Comput. Surv. (IF 23.8) Pub Date : 2025-02-07 Zehang Deng, Yongjian Guo, Changzhou Han, Wanlun Ma, Junwu Xiong, Sheng Wen, Yang Xiang
An Artificial Intelligence (AI) agent is a software entity that autonomously performs tasks or makes decisions based on pre-defined objectives and data inputs. AI agents, capable of perceiving user inputs, reasoning and planning tasks, and executing actions, have seen remarkable advancements in algorithm development and task performance. However, the security challenges they pose remain under-explored
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Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants. Science (IF 44.7) Pub Date : 2025-02-07 Hongbo Liu,Amin Abedini,Eunji Ha,Ziyuan Ma,Xin Sheng,Bernhard Dumoulin,Chengxiang Qiu,Tamas Aranyi,Shen Li,Nicole Dittrich,Hua-Chang Chen,Ran Tao,Der-Cherng Tarng,Feng-Jen Hsieh,Shih-Ann Chen,Shun-Fa Yang,Mei-Yueh Lee,Pui-Yan Kwok,Jer-Yuarn Wu,Chien-Hsiun Chen,Atlas Khan,Nita A Limdi,Wei-Qi Wei,Theresa L Walunas,Elizabeth W Karlson,Eimear E Kenny,Yuan Luo,Leah Kottyan,John J Connolly,Gail P Jarvik
Kidney dysfunction is a major cause of mortality, but its genetic architecture remains elusive. In this study, we conducted a multiancestry genome-wide association study in 2.2 million individuals and identified 1026 (97 previously unknown) independent loci. Ancestry-specific analysis indicated an attenuation of newly identified signals on common variants in European ancestry populations and the power
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MS-NeRF: Multi-Space Neural Radiance Fields IEEE Trans. Pattern Anal. Mach. Intell. (IF 20.8) Pub Date : 2025-02-07 Ze-Xin Yin, Peng-Yi Jiao, Jiaxiong Qiu, Ming-Ming Cheng, Bo Ren
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Digging Deeper in Gradient for Unrolling-based Accelerated MRI Reconstruction IEEE Trans. Pattern Anal. Mach. Intell. (IF 20.8) Pub Date : 2025-02-07 Faming Fang, Tingting Wang, Guixu Zhang, Fang Li
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C2P-Net: Comprehensive Depth Map to Planar Depth Conversion for Room Layout Estimation IEEE Trans. Pattern Anal. Mach. Intell. (IF 20.8) Pub Date : 2025-02-07 Weidong Zhang, Mengjie Zhou, Jiyu Cheng, Ying Liu, Wei Zhang
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Instruct-ReID++: Towards Universal Purpose Instruction-Guided Person Re-identification IEEE Trans. Pattern Anal. Mach. Intell. (IF 20.8) Pub Date : 2025-02-07 Weizhen He, Yiheng Deng, Yunfeng Yan, Feng Zhu, Yizhou Wang, Lei Bai, Qingsong Xie, Rui Zhao, Donglian Qi, Wanli Ouyang, Shixiang Tang
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The promise of generative AI for suicide prevention in India Nat. Mach. Intell. (IF 18.8) Pub Date : 2025-02-06 Tanmoy Chakraborty, Koushik Sinha Deb, Himanshu Kulkarni, Sarah Masud, Suresh Bada Math, Gayatri Oke, Rajesh Sagar, Mona Sharma
The World Health Organization (WHO) estimates a global suicide rate of 9 per 100,000 people, amounting to 720,000 preventable deaths each year. Despite concerted multisectoral efforts, suicide prevention remains a complex public health challenge, shaped by the interplay of socioeconomic, cultural and stress-related factors. In India, the decriminalization of suicide via the 2017 Mental Healthcare Act1
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Discovering fully semantic representations via centroid- and orientation-aware feature learning Nat. Mach. Intell. (IF 18.8) Pub Date : 2025-02-06 Jaehoon Cha, Jinhae Park, Samuel Pinilla, Kyle L. Morris, Christopher S. Allen, Mark I. Wilkinson, Jeyan Thiyagalingam
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The science behind the first pig-organ transplant trial in humans Nature (IF 50.5) Pub Date : 2025-02-04
The small trial will help to establish whether kidneys from genetically modified pigs can be transplanted into people safely and effectively.
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Fish gills and human ears share the same genetic blueprint Nature (IF 50.5) Pub Date : 2025-02-04 Ruiqi Liu, Maksim V. Plikus
Evolutionarily conserved molecular program used to form gills and ears.
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Drill, baby, drill? Trump policies will hurt climate ― but US green transition is under way Nature (IF 50.5) Pub Date : 2025-02-04
Market forces could undercut the administration’s plans to increase the use of fossil fuels such as oil and petrol.
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Daily briefing: A ‘data apocalypse’ at US public-health agencies Nature (IF 50.5) Pub Date : 2025-02-03
The month’s most stunning science images. Plus, a ‘data apocalypse’ as US public-health agencies move to comply with wide-ranging executive orders.
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How to sell your science without selling out Nature (IF 50.5) Pub Date : 2025-02-06
A five-step guide to communicating your science ethically and accurately.
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These Gaza scientists are keeping research alive amid war, destruction and uncertainty Nature (IF 50.5) Pub Date : 2025-02-06
Researchers in Gaza tell Nature of ‘unwavering commitment to education and knowledge’ as most universities lie damaged or destroyed.
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Crowd crush: Could fluid dynamics save lives? Nature (IF 50.5) Pub Date : 2025-02-05
Scientists studying the controversial 'running of the bulls' discover unique crowd movements they hope could prevent overcrowding deaths
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Crowds suck people into a vortex — surprising physicists Nature (IF 50.5) Pub Date : 2025-02-05
Studying crowd dynamics could inform strategies that help to prevent dense gatherings from becoming dangerous.
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Superfluid stiffness of twisted trilayer graphene superconductors Nature (IF 50.5) Pub Date : 2025-02-05 Abhishek Banerjee, Zeyu Hao, Mary Kreidel, Patrick Ledwith, Isabelle Phinney, Jeong Min Park, Andrew Zimmerman, Marie E. Wesson, Kenji Watanabe, Takashi Taniguchi, Robert M. Westervelt, Amir Yacoby, Pablo Jarillo-Herrero, Pavel A. Volkov, Ashvin Vishwanath, Kin Chung Fong, Philip Kim
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The genetic origin of the Indo-Europeans Nature (IF 50.5) Pub Date : 2025-02-05 Iosif Lazaridis, Nick Patterson, David Anthony, Leonid Vyazov, Romain Fournier, Harald Ringbauer, Iñigo Olalde, Alexander A. Khokhlov, Egor P. Kitov, Natalia I. Shishlina, Sorin C. Ailincăi, Danila S. Agapov, Sergey A. Agapov, Elena Batieva, Baitanayev Bauyrzhan, Zsolt Bereczki, Alexandra Buzhilova, Piya Changmai, Andrey A. Chizhevsky, Ion Ciobanu, Mihai Constantinescu, Marietta Csányi, János Dani
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Directly imaging the cooling flow in the Phoenix cluster Nature (IF 50.5) Pub Date : 2025-02-05 Michael Reefe, Michael McDonald, Marios Chatzikos, Jerome Seebeck, Richard Mushotzky, Sylvain Veilleux, Steven W. Allen, Matthew Bayliss, Michael Calzadilla, Rebecca Canning, Benjamin Floyd, Massimo Gaspari, Julie Hlavacek-Larrondo, Brian McNamara, Helen Russell, Keren Sharon, Taweewat Somboonpanyakul
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Distributed quantum computing across an optical network link Nature (IF 50.5) Pub Date : 2025-02-05 D. Main, P. Drmota, D. P. Nadlinger, E. M. Ainley, A. Agrawal, B. C. Nichol, R. Srinivas, G. Araneda, D. M. Lucas
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Cretaceous Antarctic bird skull elucidates early avian ecological diversity Nature (IF 50.5) Pub Date : 2025-02-05 Christopher R. Torres, Julia A. Clarke, Joseph R. Groenke, Matthew C. Lamanna, Ross D. E. MacPhee, Grace M. Musser, Eric M. Roberts, Patrick M. O’Connor
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Metal-halide porous framework superlattices Nature (IF 50.5) Pub Date : 2025-02-05 Wenqiang Zhang, Hong Jiang, Yikuan Liu, Yue Hu, Athulya Surendran Palakkal, Yujie Zhou, Meng Sun, Enping Du, Wei Gong, Qun Zhang, Jianwen Jiang, Jinqiao Dong, Yan Liu, Dehui Li, Yihan Zhu, Yong Cui, Xiangfeng Duan
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IL-27 elicits a cytotoxic CD8+ T cell program to enforce tumour control Nature (IF 50.5) Pub Date : 2025-02-05 Béatrice Bréart, Katherine Williams, Stellanie Krimm, Tiffany Wong, Brandon D. Kayser, Lifen Wang, Eric Cheng, Mayra Cruz Tleugabulova, Romain Bouziat, Tianshi Lu, Kobe Yuen, Natalie S. Firmino, Daniel D. Bravo, Juliette Roels, Atish Bhakta, Jack Bevers, Isabelle Lehoux, Alan Gutierrez, Yajun Chestnut, Joanna E. Klementowicz, Teresita L. Arenzana, Ilseyar Akhmetzyanova, Elizabeth Dixon, Min Chen, Kazi
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Superfluid stiffness of magic-angle twisted bilayer graphene Nature (IF 50.5) Pub Date : 2025-02-05 Miuko Tanaka, Joel Î-j. Wang, Thao H. Dinh, Daniel Rodan-Legrain, Sameia Zaman, Max Hays, Aziza Almanakly, Bharath Kannan, David K. Kim, Bethany M. Niedzielski, Kyle Serniak, Mollie E. Schwartz, Kenji Watanabe, Takashi Taniguchi, Terry P. Orlando, Simon Gustavsson, Jeffrey A. Grover, Pablo Jarillo-Herrero, William D. Oliver
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Fungal impacts on Earth’s ecosystems Nature (IF 50.5) Pub Date : 2025-02-05 Nicola T. Case, Sarah J. Gurr, Matthew C. Fisher, David S. Blehert, Charles Boone, Arturo Casadevall, Anuradha Chowdhary, Christina A. Cuomo, Cameron R. Currie, David W. Denning, Iuliana V. Ene, Lillian K. Fritz-Laylin, Aleeza C. Gerstein, Neil A. R. Gow, Asiya Gusa, Iliyan D. Iliev, Timothy Y. James, Hailing Jin, Regine Kahmann, Bruce S. Klein, James W. Kronstad, Kyla S. Ost, Kabir G. Peay, Rebecca
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Engineering a genomically recoded organism with one stop codon Nature (IF 50.5) Pub Date : 2025-02-05 Michael W. Grome, Michael T. A. Nguyen, Daniel W. Moonan, Kyle Mohler, Kebron Gurara, Shenqi Wang, Colin Hemez, Benjamin J. Stenton, Yunteng Cao, Felix Radford, Maya Kornaj, Jaymin Patel, Maisha Prome, Svetlana Rogulina, David Sozanski, Jesse Tordoff, Jesse Rinehart, Farren J. Isaacs
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Limited impact of Salmonella stress and persisters on antibiotic clearance Nature (IF 50.5) Pub Date : 2025-02-05 Joseph Fanous, Beatrice Claudi, Vishwachi Tripathi, Jiagui Li, Frédéric Goormaghtigh, Dirk Bumann
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Synthetic lethality of mRNA quality control complexes in cancer Nature (IF 50.5) Pub Date : 2025-02-05 Vivian Prindle, Adam E. Richardson, Kimberly R. Sher, Sarah Kongpachith, Kaitlin Kentala, Sakina Petiwala, Dong Cheng, Deborah Widomski, Phuong Le, Maricel Torrent, Anlu Chen, Stephen Walker, Marianne B. Palczewski, Diya Mitra, Vlasios Manaves, Xu Shi, Charles Lu, Stephanie Sandoval, Zoltan Dezso, F. Gregory Buchanan, Daniel Verduzco, Brian Bierie, Jonathan A. Meulbroek, William N. Pappano, Joshua
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Quantum coarsening and collective dynamics on a programmable simulator Nature (IF 50.5) Pub Date : 2025-02-05 Tom Manovitz, Sophie H. Li, Sepehr Ebadi, Rhine Samajdar, Alexandra A. Geim, Simon J. Evered, Dolev Bluvstein, Hengyun Zhou, Nazli Ugur Koyluoglu, Johannes Feldmeier, Pavel E. Dolgirev, Nishad Maskara, Marcin Kalinowski, Subir Sachdev, David A. Huse, Markus Greiner, Vladan Vuletić, Mikhail D. Lukin
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A genomic history of the North Pontic Region from the Neolithic to the Bronze Age Nature (IF 50.5) Pub Date : 2025-02-05 Alexey G. Nikitin, Iosif Lazaridis, Nick Patterson, Svitlana Ivanova, Mykhailo Videiko, Valentin Dergachev, Nadiia Kotova, Malcolm Lillie, Inna Potekhina, Marta Krenz-Niedbała, Sylwia Łukasik, Serhij Makhortykh, Virginie Renson, Henry Shephard, Gennadie Sirbu, Sofiia Svyryd, Taras Tkachuk, Piotr Włodarczak, Kim Callan, Elizabeth Curtis, Eadaoin Harney, Lora Iliev, Aisling Kearns, Ann Marie Lawson,
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SKI complex loss renders 9p21.3-deleted or MSI-H cancers dependent on PELO Nature (IF 50.5) Pub Date : 2025-02-05 Patricia C. Borck, Isabella Boyle, Kristina Jankovic, Nolan Bick, Kyla Foster, Anthony C. Lau, Lucy I. Parker-Burns, Daniel A. Lubicki, Tianxia Li, Ashir A. Borah, Nicholas J. Lofaso, Sohani Das Sharma, Tessla Chan, Riya V. Kishen, Anisah Adeagbo, Srivatsan Raghavan, Elisa Aquilanti, John R. Prensner, J. Michael Krill-Burger, Todd R. Golub, Catarina D. Campbell, Joshua M. Dempster, Edmond M. Chan,
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Transforming US agriculture for carbon removal with enhanced weathering Nature (IF 50.5) Pub Date : 2025-02-05 David J. Beerling, Euripides P. Kantzas, Mark R. Lomas, Lyla L. Taylor, Shuang Zhang, Yoshiki Kanzaki, Rafael M. Eufrasio, Phil Renforth, Jean-Francois Mecure, Hector Pollitt, Philip B. Holden, Neil R. Edwards, Lenny Koh, Dimitar Z. Epihov, Adam Wolf, James E. Hansen, Steven A. Banwart, Nick F. Pidgeon, Christopher T. Reinhard, Noah J. Planavsky, Maria Val Martin
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Topological water-wave structures manipulating particles Nature (IF 50.5) Pub Date : 2025-02-05 Bo Wang, Zhiyuan Che, Cheng Cheng, Caili Tong, Lei Shi, Yijie Shen, Konstantin Y. Bliokh, Jian Zi
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A comprehensive spatio-cellular map of the human hypothalamus Nature (IF 50.5) Pub Date : 2025-02-05 John A. Tadross, Lukas Steuernagel, Georgina K. C. Dowsett, Katherine A. Kentistou, Sofia Lundh, Marta Porniece, Paul Klemm, Kara Rainbow, Henning Hvid, Katarzyna Kania, Joseph Polex-Wolf, Lotte Bjerre Knudsen, Charles Pyke, John R. B. Perry, Brian Y. H. Lam, Jens C. Brüning, Giles S. H. Yeo
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RUNX2 promotes fibrosis via an alveolar-to-pathological fibroblast transition Nature (IF 50.5) Pub Date : 2025-02-05 Yinshan Fang, Sanny S. W. Chung, Le Xu, Chenyi Xue, Xue Liu, Dianhua Jiang, Rongbo Li, Yohei Korogi, Ke Yuan, Anjali Saqi, Hanina Hibshoosh, Yuefeng Huang, Chyuan-Sheng Lin, Tatsuya Tsukui, Dean Sheppard, Xin Sun, Jianwen Que
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Differential protection against SARS-CoV-2 reinfection pre- and post-Omicron Nature (IF 50.5) Pub Date : 2025-02-05 Hiam Chemaitelly, Houssein H. Ayoub, Peter Coyle, Patrick Tang, Mohammad R. Hasan, Hadi M. Yassine, Asmaa A. Al Thani, Zaina Al-Kanaani, Einas Al-Kuwari, Andrew Jeremijenko, Anvar Hassan Kaleeckal, Ali Nizar Latif, Riyazuddin Mohammad Shaik, Hanan F. Abdul-Rahim, Gheyath K. Nasrallah, Mohamed Ghaith Al-Kuwari, Adeel A. Butt, Hamad Eid Al-Romaihi, Mohamed H. Al-Thani, Abdullatif Al-Khal, Roberto Bertollini
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Multi-interface licensing of protein import into a phage nucleus Nature (IF 50.5) Pub Date : 2025-02-05 Claire Kokontis, Timothy A. Klein, Sukrit Silas, Joseph Bondy-Denomy
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Children’s arithmetic skills do not transfer between applied and academic mathematics Nature (IF 50.5) Pub Date : 2025-02-05 Abhijit V. Banerjee, Swati Bhattacharjee, Raghabendra Chattopadhyay, Esther Duflo, Alejandro J. Ganimian, Kailash Rajah, Elizabeth S. Spelke
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A neoantigen vaccine generates antitumour immunity in renal cell carcinoma Nature (IF 50.5) Pub Date : 2025-02-05 David A. Braun, Giorgia Moranzoni, Vipheaviny Chea, Bradley A. McGregor, Eryn Blass, Chloe R. Tu, Allison P. Vanasse, Cleo Forman, Juliet Forman, Alexander B. Afeyan, Nicholas R. Schindler, Yiwen Liu, Shuqiang Li, Jackson Southard, Steven L. Chang, Michelle S. Hirsch, Nicole R. LeBoeuf, Oriol Olive, Ambica Mehndiratta, Haley Greenslade, Keerthi Shetty, Susan Klaeger, Siranush Sarkizova, Christina B
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H-bonded organic frameworks as ultrasound-programmable delivery platform Nature (IF 50.5) Pub Date : 2025-02-05 Wenliang Wang, Yanshu Shi, Wenrui Chai, Kai Wing Kevin Tang, Ilya Pyatnitskiy, Yi Xie, Xiangping Liu, Weilong He, Jinmo Jeong, Ju-Chun Hsieh, Anakaren Romero Lozano, Brinkley Artman, Xi Shi, Nicole Hoefer, Binita Shrestha, Noah B. Stern, Wei Zhou, David W. McComb, Tyrone Porter, Graeme Henkelman, Banglin Chen, Huiliang Wang
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Emergence of collective oscillations in massive human crowds Nature (IF 50.5) Pub Date : 2025-02-05 François Gu, Benjamin Guiselin, Nicolas Bain, Iker Zuriguel, Denis Bartolo
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Two-dimensional polyaniline crystal with metallic out-of-plane conductivity Nature (IF 50.5) Pub Date : 2025-02-05 Tao Zhang, Shu Chen, Petko St. Petkov, Peng Zhang, Haoyuan Qi, Nguyen Ngan Nguyen, Wenjie Zhang, Jiho Yoon, Peining Li, Thomas Brumme, Alexey Alfonsov, Zhongquan Liao, Mike Hambsch, Shunqi Xu, Lars Mester, Vladislav Kataev, Bernd Büchner, Stefan C. B. Mannsfeld, Ehrenfried Zschech, Stuart S. P. Parkin, Ute Kaiser, Thomas Heine, Renhao Dong, Rainer Hillenbrand, Xinliang Feng