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The impact of soybean meal and field peas inclusion on growth performance, carcass traits and nutrient digestibilities in broiler chickens offered wheat-based diets Anim. Nutr. (IF 6.1) Pub Date : 2025-05-31 Milan Kandel, Mehdi Toghyani, Shemil P. Macelline, Peter H. Selle, Ruth N. Zadoks, Sonia Yun Liu
Replacing soybean meal (SBM) in broiler diets with only other plant-based protein-rich ingredients or only non-bound amino acids (NBAA) may compromise growth performance in broiler chickens. However, combining both to replace SBM may be feasible while maintaining broiler performance. A 3 × 2 full factorial designed experiment was conducted to include three levels of SBM inclusions (conventional, medium
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Effects of red clover isoflavone on lactation performance, milk quality and nitrogen metabolism in dairy cows Anim. Nutr. (IF 6.1) Pub Date : 2025-05-31 Zhanbo Xiong, Xiaoyin Zhang, Shiqi Zhang, Kexin Li, Yuan Gao, Ying Bu, Nan Zheng, Shengguo Zhao, Jiaqi Wang
Reducing nitrogen loss and improving nitrogen utilization efficiency in dairy cows can reduce economic costs and mitigate the environmental impact of nitrogen emissions. Red clover isoflavone, a natural compound derived from plant extract, has the advantage of biological safety. This study aimed to investigate the effects of red clover isoflavone on lactation performance and nitrogen metabolism in
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Optimizing dietary crude protein, branched-chain amino acids, and energy levels for broiler performance using a Box-Behnken design Anim. Nutr. (IF 6.1) Pub Date : 2025-04-25 Sosthene Musigwa, Pierre Cozannet, Mingan Choct, Shu-Biao Wu
This study aimed to investigate the limitations and interactive effects of dietary crude protein (CP; 15%, 17% and 19%), excess branched-chain amino acid (BCAA) inclusions (0%, 20% and 40%), and net energy (NE; 9.0, 9.7 and 10.4 MJ/kg) on performance and nutrient utilization for Cobb 500 mix-sex broilers, using a Box-Behnken design. The study consisted of 2 experiments: Exp. 1 involved 1092 chickens
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The 14th China national symposium on animal nutrition: Embracing precision, efficiency, and innovation towards a greener future Anim. Nutr. (IF 6.1) Pub Date : 2025-04-11 Chenbin Cui, Jing Wu, Min Tian, Xuefen Yang, Zongyong Jiang
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Supplementation of the probiotic Lactobacillus rhamnosus GG to pre-weaning calves decreases diarrhea incidence by modulating gut bacteria and associated metabolites Anim. Nutr. (IF 6.1) Pub Date : 2025-04-11 Haoqi Han, Kaizhen Liu, Yao Wang, Mingming Song, Hongxia Lian, Tengyun Gao, Liyang Zhang, Tong Fu
The aim of the present study was to investigate whether Lactobacillus rhamnosus GG (LGG) could be utilized as an effective strategy to promote growth performance of calves and to further study its impact on decreasing diarrhea. A total of 18 healthy Holstein calves (age 8 ± 3 days, weight 42.48 ± 1.04 kg) were raised in a centralized manner to minimize differences and then divided into two groups:
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Dietary arachidonic acid improves the growth performance, anti-oxidant capacity and ovary development of female rice field eel broodstocks (Monopterus albus) Anim. Nutr. (IF 6.1) Pub Date : 2025-04-08 Huamei Yue, Peng Fu, Haichao Deng, Rui Ruan, Huan Ye, Chuang Zhang, Chuangju Li
Arachidonic acid (ARA) is crucial for the growth, antioxidant capacity, and reproductive performance of fish. This study was conducted to assess the impact of dietary ARA on female rice field eel (Monopterus albus) broodstocks. A total of 600 eels, averaging 117.96 ± 3.65 g, were randomly distributed into 12 tanks, with each tank containing 50 fish. Four isonitrogenous and isolipidic diets comprising
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Impacts of dietary arginine supplementation on performance, nutrient digestion and expression of proteins related to milk fatty acid and casein synthesis in early lactating dairy cows Anim. Nutr. (IF 6.1) Pub Date : 2025-04-07 Jing Zhang, Jiaojiao Lang, Lijun Bu, Yapeng Liu, Wenjie Huo, Caixia Pei, Qiang Liu
Arginine (Arg) can potentially increase milk yields in early lactating dairy cows by stimulating the development of mammary gland and the biosynthesis of milk proteins and fatty acids (FA); however, the underlying mechanism is still unclear. The hypothesis that rumen-protected Arg addition would increase milk, milk fat, and milk protein yields was tested, aiming to dlucidate the possible mechanism
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Arecoline regulates glycolipid and endoplasmic reticulum metabolisms in adult grass carp (Ctenopharyngodon idella) Anim. Nutr. (IF 6.1) Pub Date : 2025-04-05 Liangqin Wu, Na Yao, Weidan Jiang, Pei Wu, Yang Liu, Yaobin Ma, Hongmei Ren, Xiaowan Jin, Hequn Shi, Xiaoqiu Zhou, Lin Feng
Arecoline is an alkaloid extracted from the plant betel nut with important pharmacological effects and is an agonist at muscarinic receptors (M receptors). In this study, we investigated the effects of dietary arecoline supplementation on hepatopancreatic and muscle glycolipid metabolism in adult grass carp (Ctenopharyngodon idellus). A total of 450 healthy adult grass carp with an initial body weight
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Impacts of feeding different lipid sources on serum biochemical indices, dietary fatty acid metabolism, raw foie gras quality characteristics and gene expression related to fat deposition in the Landes goose Anim. Nutr. (IF 6.1) Pub Date : 2025-04-05 Ran An, Yaxin Wang, Qingchang Ren
This study investigated the impacts of feeding different lipid sources on raw goose foie gras quality characteristics. A total of 1080 Landes geese at 60 d old with body weight 3.87 ± 0.13 kg (mean ± SEM) were randomly assigned to three treatments: a corn meal-based diet with 25 g/kg soybean oil, with 25 g/kg goose fat, or with 15 g/kg goose fat plus 10 g/kg soybean oil (MIX). Each treatment was split
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Multiple ways to promote adult grass carp (Ctenopharyngodon idella) muscle hypertrophy: Application of dietary myo-inositol Anim. Nutr. (IF 6.1) Pub Date : 2025-04-05 Meiqi Wang, Lin Feng, Pei Wu, Yang Liu, Hongmei Ren, Xiaowan Jin, Xiaoqiu Zhou, Weidan Jiang
Skeletal muscle constitutes the largest tissue in fish and represents the primary edible portion. Given the substantial differences in muscle growth dynamics between fish and mammals, fish serve as a crucial and distinctive model organism for investigating the fundamental mechanisms of growth regulation in vertebrates. Myo-inositol (MI), originally discovered in muscle, plays significant biological
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Transcriptomic analysis of muscle and adipose tissues identifies myokines and adipokines contributing to lipid deposition in Taoyuan Black pigs Anim. Nutr. (IF 6.1) Pub Date : 2025-04-05 Liu Guo, Junfei Xu, Wenyue Zhou, Sisi Chen, Hanjing Shi, Mengmeng Han, Weijun Pang, Yulong Yin, Fengna Li
Meat quality and lean meat percentage are important to pig industry. Muscle and adipose tissues are regarded as secretory organs that release myokines and adipokines to mediate muscle-adipose tissue crosstalk, which regulates lipid deposition and skeletal muscle development. The Taoyuan Black (TB) pig, a Chinese indigenous breed, exhibits abundant lipid deposition and is known for excellent meat quality
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Dietary energy and protein gradients drive metabolic adaptation in growing-finishing yaks on the Qinghai-Tibet plateau Anim. Nutr. (IF 6.1) Pub Date : 2025-04-05 Shoupei Zhao, Jia Zhou, Shengtao Guan, Xiaolin Wang, Xiao Wen, Kaiqiang Zhao, Huaming Yang, Lianghao Lu, Bao Zhang, Yuanyuan Chen, Quanhui Peng, Lizhi Wang, Zhisheng Wang, Bai Xue
The study investigated the metabolic responses of yaks to dietary net energy for gain (NEg) and metabolizable protein (MP), and explored potential biomarkers for average daily gain (ADG) in serum metabolites. A total of 40 three-year-old yaks (initial body weight = 255 ± 8.04 kg) were assigned to a 2 × 2 factorial treatment arrangement based on dietary NEg (4.18 vs 4.81 MJ/kg DM; low NEg [LE] vs high
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Increasing concentrate feeding level in early lactation dairy cows fed cut herbage linearly decreased methane yield and intensity Anim. Nutr. (IF 6.1) Pub Date : 2025-04-05 Maria M. Della Rosa, Troy J. Bosher, M. Ajmal Khan, Edgar Sandoval, German Molano, Brenna Dobson-Hill, Federico N. Duranovich, Arjan Jonker
The use of supplementary feeds, including concentrates, on New Zealand dairy farms has increased in recent decades and this could have mitigated methane (CH4) emissions by decreasing the forage-to-concentrate ratio. The forage-to-concentrate ratio in the diet can be easily managed in cows that receive a total mixed ration, but under grazing conditions, the cows select their own diets by increasing
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The role of glycosylated mucins in maintaining intestinal homeostasis and gut health Anim. Nutr. (IF 6.1) Pub Date : 2025-04-04 Hao Cheng, Hao Li, Zhong Li, Yun Wang, Liangguo Liu, Jing Wang, Xiaokang Ma, Bie Tan
The intestinal mucus barrier is a crucial component of the host's innate defense system, playing a vital role in regulating intestinal microecology and maintaining intestinal homeostasis. Glycosylated mucins, the core components of this barrier, are essential for preserving its integrity by preventing bacterial degradation. Additionally, mucins significantly contribute to establishing a balanced symbiotic
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Weaning performance prediction in lactating sows using machine learning, for precision nutrition and intelligent feeding Anim. Nutr. (IF 6.1) Pub Date : 2025-04-01 Jiayi Su, Xiangfeng Kong, Wenliang Wang, Qian Xie, Chengming Wang, Bie Tan, Jing Wang
Traditional feeding strategy during lactation can result in nutrient deficiencies and negatively impact long-term productivity, compromising both the sustainability and profitability of the swine industry. Precision feeding, supported by decision-making systems built on advanced predictive models, offers a promising solution to address these challenges. This study aimed to develop prediction models
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Integrative analysis of metabolomics and transcriptomics reveals alterations in egg quality and hepatic lipid metabolism in hens supplemented with curcumin Anim. Nutr. (IF 6.1) Pub Date : 2025-03-28 Cunzhi Zou, Haiyu Jiang, Xuanfu Wu, Jiang Gao, Wenqiang Ma
Curcumin has been shown to affect lipid metabolism in various ways, but its molecular mechanisms in hens remain poorly understood. In this study, 378 Hy-Line Brown hens, aged 58 weeks, were randomly assigned into three groups, each consisting of 6 replicates with 21 hens per replicate. The control group was fed a basal diet, while the experimental groups received diets supplemented with either 50 or
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Digestion kinetics of protein feed ingredients and their impact on nitrogen utilization in growing pigs Anim. Nutr. (IF 6.1) Pub Date : 2025-03-28 Jia Li, Yu Cao, Xiaoyi Yu, Jingyi Huang, Rouke Jiang, Mingyi Huang, Jinbiao Zhao, Dandan Han, Junjun Wang
The velocity of nitrogen release impacts nitrogen utilization efficiency and animal growth. Yet the crucial junctures linking nitrogen release and utilization from diverse feed ingredients to digestion kinetic parameters remain obscure. This study aimed to evaluate and subdivide in vitro protein digestion characteristics (such as release rate of free amino acids [FAA]) of three commonly used protein
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Determination of optimal dietary calcium levels under different zinc sources in Jing Tint 6 layer chicks from hatch to day 14 Anim. Nutr. (IF 6.1) Pub Date : 2025-03-28 Chengyan Gong, Hongpeng Shi, Shuan Liu, Xinyi Gao, Shoujun Zhang, Hao Liu, Dan Wan, Yulong Yin
An experiment was conducted to investigate the optimal dietary calcium (Ca) levels in Jing Tint 6 layer chicks fed different sources of zinc (Zn). A total of 1440 day-old birds with similar body weight (38 ± 0.5 g) were selected and divided into 10 groups with 6 replicates per group, each containing 24 chicks. The experimental period lasted from hatch to d 14. Diets were formulated to contain 2 sources
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A perception that the feed grain basis of reduced-crude protein diets modifies the anabolic impact of insulin on the growth performance of broiler chickens Anim. Nutr. (IF 6.1) Pub Date : 2025-03-27 Peter H. Selle, Shemil P. Macelline, Mengzhu Z. Wang, Sonia Yun Liu
This inherently speculative review provides a perception that the feed grain basis of a reduced-crude protein (CP) diets modifies the anabolic impact of insulin in broiler chickens for the first 21 to 28 days post-hatch. Insulin is a powerful anabolic hormone in non-ruminant, mammalian species; however, the importance of insulin in avian species is usually dismissed because broiler chickens are held
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Effects of dietary cinnamaldehyde supplementation in the perinatal period on reproductive performance, milk composition, redox status and gut microbiota of sows Anim. Nutr. (IF 6.1) Pub Date : 2025-03-26 Junqi Jin, Shiya Liu, Xie Peng, Changqin Wang, Qiang Zhou, Zhengfeng Fang, Yan Lin, Shengyu Xu, Bin Feng, Yong Zhuo, Hua Zhao, De Wu, Lianqiang Che
Improving sow health during the perinatal period is crucial for reproductive performance. Cinnamaldehyde (CA), a naturally occurring compound, is known for its anti-inflammatory, antioxidant, and gut microbiota-modulating properties. This study evaluated the effects of dietary CA supplementation during the perinatal period on reproductive performance, milk composition, redox status, and gut microbiota
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Rumen microbiota associated with feed efficiency in beef cattle are highly influenced by diet composition Anim. Nutr. (IF 6.1) Pub Date : 2025-03-15 Abimael Ortiz-Chura, Karla Fabiola Corral-Jara, Jeremy Tournayre, Gonzalo Cantalapiedra-Hijar, Milka Popova, Diego P. Morgavi
Given the role of the rumen microbiome in providing nutrients to the host ruminant, it is expected that rumen microbes contribute to inter-animal variations in feed efficiency. However, the link between microbial structure and an “efficient” host phenotype is unclear. We hypothesized that extreme residual feed intake (RFI) phenotypes would display distinctive microbiome features regardless of the diet
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Fibroblast growth factor 21/extracellular signal-regulated kinase 1/2 pathway as a key link mediates the effects of low-protein diet on skeletal muscle fiber type transformation in pigs Anim. Nutr. (IF 6.1) Pub Date : 2025-03-08 Shuo Li, Pengbo Liang, Bo Wang, Jun Chen, Jinming You, Tiande Zou
Low-protein (LP) diets play a pivotal role in inducing skeletal muscle remodeling toward an oxidative phenotype in pigs, the underlying targets and mechanisms remain uncertain. This study aimed to investigate whether fibroblast growth factor 21 (FGF21), an endocrine signal associated with low protein intake, mediates the effect of LP diets on myofiber type transition in pigs. Twenty-four healthy castrated
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Nettle supplementation improves antioxidant status and modulates inflammatory response by altering lysophosphatidylcholines and enterolactone metabolism in dairy cows Anim. Nutr. (IF 6.1) Pub Date : 2025-03-06 Qian Zhang, Na Ta, Jize Zhang, Xiaozhen Liu, He Ding, Xiaoqing Zhang
Nettle is not only a nutrient-rich forage but also possesses the potential to act as a nutritional and physiological regulator. This study investigated the effects of supplementing nettle hay into the total mixed rations (TMR) on milk yield, milk composition, antioxidant capacity, immune function, and plasma metabolome in dairy cows. Twenty multiparous Holstein cows with similar days in milk (102 ±
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Effects of ambient temperature, energy density, and energy source on energy partition and plasma metabolomics profile of finishing pigs Anim. Nutr. (IF 6.1) Pub Date : 2025-03-06 Dan Jiang, Kai Zhou, Dongsheng Che, Hailong Jiang, Rui Han, Guixin Qin
Ambient temperature is an important factor affecting metabolic processes in animals, and its effect on energy metabolism is becoming more evident. Yet, integrative analysis of energy metabolism in finishing pigs at different combinations of ambient temperature, energy density and energy sources, still remain underexplored. In order to determine the special characteristics of energy metabolism of finishing
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Oyster mushroom fermented Vachellia erioloba pods as replacement for wheat bran in broiler diets: Physiology and meat physicochemical and nutritional quality Anim. Nutr. (IF 6.1) Pub Date : 2025-03-05 Phethile E. Mabuza, Makiwa S. Mthana, Doctor M.N. Mthiyane
High feed costs and compromised meat quality are among the major issues perturbing the global broiler industry. This study therefore investigated Vachellia erioloba pods-derived oyster mushroom spent substrate (OMSS) as a potential nutraceutical feed ingredient to replace wheat bran for enhancing meat quality in broilers. Four hundred male Ross 308 chicks at 14 d of age were randomly allocated to 40
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Effects of increasing levels of dietary cation–anion difference on growth performance, nutrient digestibility, rumen fermentation, and rumen microbiota in fattening Hu sheep Anim. Nutr. (IF 6.1) Pub Date : 2025-03-03 Yu Wang, Wenjin Zheng, Hongwei Duan, Jiazhi Luo, Yuyang Yin, Junshi Shen, Shengyong Mao, Weiyun Zhu, Zhongtang Yu
The dietary cation–anion difference (DCAD) has the potential to influence the physiological functions of animals. Nonetheless, there is a notable scarcity of research in the field of ruminant science regarding its effects on fattening sheep, particularly with respect to the rumen microbiota. Therefore, this study evaluated the effects of varied DCAD levels on growth performance, rumen fermentation
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Myotonic dystrophy-related CDC42-binding kinase alpha (MRCKα) mediates methionine- and leucine-stimulated β-casein synthesis in bovine mammary epithelial cells via targeting mTOR Anim. Nutr. (IF 6.1) Pub Date : 2025-02-15 Fang Wang, Jürgen van Baal, Lu Ma, Xuejun Gao, Jan Dijkstra, Dengpan Bu
Amino acids (AA), including methionine (Met) and leucine (Leu), stimulate milk synthesis in bovine mammary epithelial cells (BMEC) via activation of protein kinase mechanistic target of rapamycin (mTOR). In this study, we further explored the potential role of myotonic dystrophy-related CDC42-binding kinase alpha (MRCKα), previously identified as a critical mediator of prolactin-stimulated milk synthesis
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Prebiotics in animal nutrition: Harnessing agro-industrial waste for improved gut health and performance Anim. Nutr. (IF 6.1) Pub Date : 2025-02-14 M. Cristina Ravanal, Carolina A. Contador, Wing-Tak Wong, Qile Zhang, Analese Roman-Benn, Kong Shun Ah-Hen, Pilar E. Ulloa, Hon-Ming Lam
This review provides an overview of the current research on prebiotics and their applications in animal nutrition and health. Various types of prebiotics are introduced and classified, with an analysis of agro-industrial residues as sources. The potential of prebiotics as substrates for the growth and/or activity of probiotic microorganisms, as well as their applications in animal feeds, were examined
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Transcriptome analysis reveals the mechanism by which fermented Broussonetia papyrifera influences meat quality of Taihe black-bone silky fowl Anim. Nutr. (IF 6.1) Pub Date : 2025-02-13 Wei Wei, Yang Fu, Weifa Su, Wentao Li, Lixia Kai, Jingzhan Liang, Fengqin Wang, Changyou Shi, Yizhen Wang, Zeqing Lu
This study was designed to investigate the effects of Fermented Broussonetia papyrifera (FBP) on growth performance, meat quality, and the expression of meat quality-related genes in Taihe black-bone silky fowl (TBsf). In the present study, 360 ninety-day-old TBsfs (body weight = 781 ± 0.85 g) were divided into 4 groups with 5 replicates (18 hens per replicate), of which the control group was fed the
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Impact of krill (Euphausia superba) meal on growth performance of aquatic animals: A meta-analysis and prospective directions Anim. Nutr. (IF 6.1) Pub Date : 2025-02-12 Hung Quang Tran, Tram Thi Nguyen, Markéta Dvořáková Prokešová, Margareth Øverland, Laura Gasco, Vikas Kumar, Hien Van Doan, Vlastimil Stejskal
Antarctic krill meal (KM) (Euphausia superba) as a substitute for fishmeal in aquatic animal diets is gaining popularity worldwide. A quantitative approach investigating the efficacy of using this protein on the production performance of aquatic animals remains widely limited. Here, we employed a meta-analysis to quantify the overall effects (Hedges’g [g] value effect size) of KM on the specific growth
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Supplementation of lentinan improves lactation performance by altering ruminal microorganisms and metabolites in dairy cows Anim. Nutr. (IF 6.1) Pub Date : 2025-02-08 Lun Tan, Xiao Li, Caiyun Fan, Dian Wang, Shuaihong Li, Yuhang Ding, Zixi Yang, Zhao Zhuo, Jianbo Cheng
Lentinan (LNT) is a bioactive polysaccharide that has been proven to improve the production performance of animals. The objective of this study was to investigate the effects of LNT on lactation performance and rumen fermentation in dairy cows. Through random block design, 80 Holstein cows were randomly assigned to four treatments (CON, control group, fed a basal diet; and 5LNT, 10LNT, 15LNT groups
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Mitigating enteric methane emissions: An overview of methanogenesis, inhibitors and future prospects Anim. Nutr. (IF 6.1) Pub Date : 2025-02-08 Xin Xie, Yurong Cao, Qiushuang Li, Qi Li, Xingze Yang, Rong Wang, Xiumin Zhang, Zhiliang Tan, Bo Lin, Min Wang
Enteric methane emissions account for approximately 17% of global anthropogenic greenhouse gas emissions and represent 2% to 12% of energy losses from energy intake in ruminants. To reduce these emissions and accelerate the achievement of carbon neutrality, it is critical to understand the factors driving methanogenesis in the rumen and develop effective methane mitigation strategies. Methanogenesis
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Black soldier fly larvae oil can partially replace fish oil in the diet of the juvenile mud crab (Scylla paramamosain) Anim. Nutr. (IF 6.1) Pub Date : 2025-02-08 Yuhang Yang, Tingting Zhu, Min Jin, Xiangkai Li, Shichao Xie, Yuhui Cui, Qicun Zhou
An 8-week feeding trial was conducted to investigate the effects of replacing dietary fish oil (FO) with black soldier fly larval oil (BSFO) on growth performance, antioxidant and immune response, lipid metabolism and mitochondrial function of the juvenile mud crab. A total of 160 mud crabs (18.58 ± 0.02 g) were randomly distributed into five treatments spread across 160 aquaria. There were 4 replicates
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Yellow mealworm (Tenebrio molitor) meal in diets of grass carp (Ctenopharyngodon idellus): Effects on growth performance, antioxidant capacity, immunity, intestinal morphology, and intestinal microbiota Anim. Nutr. (IF 6.1) Pub Date : 2025-01-29 Linlin Yang, Minglang Cai, Lei Zhong, Yulong Yin, Yonghong Xie, Shouqi Xie, Yi Hu, Junzhi Zhang
The impacts of substituting dietary soybean meal (SBM) with yellow mealworm meal (YMM) were investigated during a 56-day feeding trial on growth, antioxidant capacity, immunity, intestinal morphology, and intestinal microbiota of grass carp. A total of 750 grass carp were divided into 5 groups (3 replications per group and 50 fish per replication) with different levels of YMM: SBM (control group),
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Multi-omics interpretation of how lysophospholipids regulate hepatic lipid metabolism and immunity in hybrid grouper (♀Epinephelus fuscoguttatus × ♂Epinephelus Lanceolatu) fed high-lipid diets Anim. Nutr. (IF 6.1) Pub Date : 2025-01-27 Hongjin Deng, Jiacheng Zhang, Weixing Liang, Beiping Tan, Shuyan Chi
This experiment explored the effects of lysophospholipids on hybrid grouper (initial average weight: 22.65 ± 0.03 g) hepatic lipid metabolism and immunity at the transcriptome and metabolome levels. A total of 375 hybrid groupers were divided into 5 groups of 3 replicates of 25 fish each. Five isoproteic and isolipidic diets were formed by adding 0 (L0, control group), 0.05% (L0.05), 0.1% (L0.1), 0
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Mechanism of fumonisin B1 on growth performance and intestinal structural integrity of juvenile grass carp (Ctenopharyngodon idella) Anim. Nutr. (IF 6.1) Pub Date : 2025-01-25 Daiyu Chen, Weidan Jiang, Pei Wu, Yang Liu, Hongmei Ren, Xiaowan Jin, Xiaoqiu Zhou, Lin Feng
Fumonisin B1 (FB1) is a prevalent mycotoxin found in plant-based feed ingredients, and it negatively impacts the performance of aquatic animals. However, the mechanism of this toxicity remains unclear. This study aims to investigate the effect and underlying mechanism of dietary FB1 on the growth performance of juvenile grass carp (Ctenopharyngodon idella). A total of 720 juvenile grass carp (10.92
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Multi-omics analysis provides new insights into the molecular mechanisms underlying colostral immunoglobulin G absorption in the gut of neonatal goat kids Anim. Nutr. (IF 6.1) Pub Date : 2025-01-25 Chao Yang, Yan Cheng, Tianxi Zhang, Kefyalew Gebeyew, Amanda Fischer-Tlustos, Leluo Guan, Michael Steele, Zhiliang Tan, Zhixiong He
Early colostrum feeding facilitates the passive transfer of immunoglobulin G (IgG), which contributes to the defensive establishment of neonates; however, the molecular mechanisms of IgG absorption in the small intestine of neonatal mammals remain largely unknown. In this study, a total of 16 neonatal goat kids with similar body weight (2.05 ± 0.31 kg) were selected and randomly assigned to 1 of 2
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Effect of three polychaetes on growth and reproductive performance, biochemical indices and histology of different tissues in the female Pacific white shrimp, Litopenaeus vannamei broodstock Anim. Nutr. (IF 6.1) Pub Date : 2025-01-20 Shuaipeng Li, Hao Liu, Weibin Huang, Shipei Yang, Mingsheng Xie, Menglong Zhou, Baiquan Lu, Biao Li, Beiping Tan, Yuanzhi Yang, Xiaohui Dong
A 30-day feeding trial was conducted to assess the effect of three fresh-live polychaetes as diets on growth and reproductive performance, biochemical indices and histology of different tissues in female Pacific white shrimp (Litopenaeus vannamei) broodstock. Two novel polychaete species, Marphysa maxidenticulata (MM group) and Perinereis nuntia (PN group), and a traditional species, Perinereis aibuhitensis
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Dietary supplementation of Scutellariae radix flavonoid extract improves lactation performance in dairy cows by regulating gastrointestinal microbes, antioxidant capacity and immune function Anim. Nutr. (IF 6.1) Pub Date : 2025-01-18 Dongwen Dai, Chunxiao Dong, Fanlin Kong, Shuo Wang, Shuxiang Wang, Wei Wang, Shengli Li
Scutellariae radix flavonoid extract (SFE) has been acknowledged for its antioxidant, anti-inflammatory and antimicrobial properties in enhancing gastrointestinal microbial communities and improving the host’s immunity. Nevertheless, the impacts of dietary supplementation with SFE on the gastrointestinal microbes and host metabolism in dairy cows remain uncertain. Therefore, the aim of this study was
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Astaxanthin supplementation mitigated intestinal damage and immunity in overfed Pekin ducks by regulating gut morphology, intestinal inflammation, and antioxidant balance Anim. Nutr. (IF 6.1) Pub Date : 2025-01-16 Xueze Lv, Uchechukwu Edna Obianwuna, Weifang Yang, Ziyue Zhang, Keying An, Bozhi Shi, Yingchao Dong, Shugeng Wu, Zhaofei Xia
This study explored the impact of astaxanthin (AST) supplementation on growth performance, serum lipid profile, gut morphology, and antioxidant and immune function in the intestinal mucosa of Pekin ducks subjected to overfeeding. A total of 150 male Pekin ducks at one day of age were randomly allotted into five treatment groups with five replicates of six ducks each. The control group and ad libitum
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Revealing the physical restrictions of caecal influx in broilers through the use of solid and soluble markers Anim. Nutr. (IF 6.1) Pub Date : 2025-01-16 Paulien Vanderghinste, An Bautil, Michael R. Bedford, Gemma González-Ortiz, Chris Lamberigts, Imran Aslam, Maarten Roeffaers, Christophe M. Courtin
A promising strategy to support broiler health and performance in a sustainable way is the enhancement of microbial fibre fermentation in broilers. This fermentation mainly occurs in the caeca, but the actual particle size range that allows caecal influx has not yet been described. This study aimed to understand the physical limitations of caecal influx as a function of broiler age by using both solid
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Different types of bile acids exhibit opposite regulatory effects on lipid metabolism in finishing pigs through bile acid receptors Anim. Nutr. (IF 6.1) Pub Date : 2024-12-31 Yaolian Hu, Ni Sang, Aimin Wu, Junning Pu, Hui Yan, Junqiu Luo, Ping Zheng, Yuheng Luo, Jie Yu, Jun He, Bing Yu, Daiwen Chen
The purpose of this research was to investigate how different bile acids impact lipid metabolism and carcass characteristics in finishing pigs, along with the potential mechanisms involved. Twenty-one finishing pigs (Duroc×Landrace×Yorkshire [DLY]; average BW = 144.38 ± 8.92 kg) were assigned to three dietary treatments, with each treatment containing seven replicates, each consisting of one pig. The
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Maternal consumption of glycerol monolaurate optimizes milk fatty acid profile and enhances piglet gut health in association with G protein-coupled receptor 84 (GPR84) activation Anim. Nutr. (IF 6.1) Pub Date : 2024-12-31 Liang Xiong, Zhijin Zhang, Shiqi Dong, Tongbin Lin, Xianhuai Yue, Fang Chen, Wutai Guan, Shihai Zhang
This study evaluated the effect of maternal glycerol monolaurate (GML) supplementation during late gestation and lactation on sow reproductive performance, transfer of immunity and redox status, milk fat and fatty acid profile, and fecal microbiota. Eighty multiparous sows (Landrace × Large white) were randomly allocated to two treatment groups (with or without 1000 mg/kg GML) with 40 replicates per
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Bacillus pumilus 315 improves intestinal microbiota and barrier function to alleviate diarrhea of neonatal goats Anim. Nutr. (IF 6.1) Pub Date : 2024-12-30 Dingkun Fan, Shuai Jiao, Yuze Fu, Jixian Zhang, Yimin Zhuang, Juan Huang, Yanliang Bi, Jianxin Zhang, Naifeng Zhang
Diarrhea is the leading cause of mortality in postnatal goat kids, seriously impacting breeding efficiency. This study aimed to explore the effects of Bacillus pumilus 315 (B. pumilus) on goat kids’ diarrhea and its regulatory mechanism. Thirty-six 1-day-old goat kids were assigned into four treatments, the control (CON) group and low-, medium- and high-dose groups supplemented with B. pumilus at 1 × 108
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Maternal dietary inulin intake during late gestation and lactation ameliorates intestinal oxidative stress in piglets with the involvements of gut microbiota and bile acids metabolism Anim. Nutr. (IF 6.1) Pub Date : 2024-12-28 Dongdong Lu, Cuiping Feng, Yu Pi, Hao Ye, Yujun Wu, Bingxu Huang, Jinbiao Zhao, Dandan Han, Nicoline Soede, Junjun Wang
Maternal inulin intake has been shown to alleviate oxidative stress in piglets, but the role of bile acids (BAs) in this process remains unknown. This study aimed to investigate the roles of gut microbiota and BAs metabolism in the amelioration of intestinal oxidative stress in piglets through a maternal inulin diet. A total of 40 sows were allocated into two dietary treatments from day 85 of gestation
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Impact of dietary forage proportion and crossbreeding on feed efficiency and methane emissions in lactating dairy cows Anim. Nutr. (IF 6.1) Pub Date : 2024-12-28 Sabrina Ormston, Tianhai Yan, Xianjiang Chen, Alan W. Gordon, Katerina Theodoridou, Sharon Huws, Sokratis Stergiadis
Increasing forage proportion (FP) in the diets of dairy cows would reduce competition for human edible foods and reduce feed costs, particularly in low-input systems. However, increasing FP reduces productivity and may increases methane (CH4) emission parameters. This work aimed to investigate the impact of FP and breed on feed efficiency and CH4 emission parameters. Data from 32 individual experiments
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Effects of peroxidized lipids on intestinal morphology, antioxidant capacity and gut microbiome in piglets Anim. Nutr. (IF 6.1) Pub Date : 2024-12-27 Mengxuan Tang, Yuliang Wu, Chen Guang Olnood, Yundi Gao, Fei Wang, Zicheng Zhang, Can Peng, Xihong Zhou, Chunxia Huang, Xia Xiong, Yulong Yin
This study investigated the effect of peroxidized lipids on piglets’ growth performance, intestinal morphology, inflammatory reactions, oxidative stress in the liver, duodenum, jejunum, ileum, and colon, and ileal microbiota. Twenty piglets (Duroc × [Landrace × Yorkshire]; age = 21 d old, BW = 6.5 ± 1 kg) were randomly assigned to two groups with 10 replicates per group and one piglet per replicate
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Evaluation of ginger straw as a forage source for goats: Effects on performance, ruminal fermentation, meat quality and immunity Anim. Nutr. (IF 6.1) Pub Date : 2024-12-22 Xiaokang Lv, Min Zhang, Ke Ji, Chuanshe Zhou, Jinling Hua
This study aimed to investigate the effects of ginger straw as a replacement of peanut straw on the growth, meat quality, rumen fermentation, and immunity of goats. In this study, 40 Huanghuai male goats, weighing 30 ± 0.5 kg at six months of age, were selected and randomly divided into four treatments: ginger straw 0% (G0), 5% (G5), 10% (G10) and 20% (G20) replacing peanut straw, with 10 goats in
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Dietary supplementation with isochlorogenic acid improves growth performance and intestinal health of broilers Anim. Nutr. (IF 6.1) Pub Date : 2024-12-17 Siyuan Zhou, Haotian Jiang, Yujia Wang, An Yan, Guohua Liu, Shudong Liu, Baojiang Chen
This study evaluated the effects of dietary supplementation with isochlorogenic acid (ICA) on growth performance and intestinal health of broilers. A total of 400 Cobb broilers (44.20 ± 0.16 g, one day old) were randomly assigned to 5 treatments (ICA supplementation at 0, 500, 1000, 2000, and 3000 mg/kg diet) with 8 replicates of 10 birds each. The experimental trial lasted for 42 d. The feed-to-gain
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Folic acid alleviates the negative effects of dexamethasone induced stress on production performance in Hyline Brown laying hens Anim. Nutr. (IF 6.1) Pub Date : 2024-12-14 Xi Sun, Chaohui Wang, Sijing Li, Xiaoying Liu, Yun Li, Yumeng Wang, Yuxin Niu, Zhouzheng Ren, Xin Yang, Xiaojun Yang, Yanli Liu
Multiple stressors are believed to deteriorate production performance and cause substantial economic losses in commercial poultry farming. Folic acid (FA) is an antioxidant compound that can improve oocyte function and regulate gut microbiota composition. The current study was conducted to investigate the role of FA in alleviating stress and improving production performance. Sixty Hyline Brown laying
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Replacing rice straw with peanut vine and Broussonetia papyrifera silage in beef cattle feed reduced the use of soybean meal Anim. Nutr. (IF 6.1) Pub Date : 2024-12-13 Xin Yi, Yueming Li, Yue Liu, Minzhe Zhang, Zhenming Zhou, Qingxiang Meng, Hao Wu
The present study investigated whether replacing dietary rice straw with peanut vine (PEV) and Broussonetia papyrifera silage (BPS) reduces the use of soybean meal and explored its effects on the growth performance, blood biochemical indicators, serum metabolomics, and meat quality of fattening bulls. Forty-five Simmental crossbred bulls (initial body weight = 484.29 ± 8.49 kg) were randomly allotted
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Transcriptome analysis reveals modulations in glycosylation profiles of the mucosal barrier and their potential interaction with gut microbiota in weaned piglets Anim. Nutr. (IF 6.1) Pub Date : 2024-12-10 Hao Cheng, Hao Li, Yujie Zhao, Kai Yang, Jing Wang, Bie Tan, Xiaokang Ma
The current study aims to investigate the potential interaction between glycosylation profiles of the Ningxiang breed (NX) and Western Duroc × Landrace × Yorkshire breed (DLY) weaned piglets, and their characteristic microbes, employing integrated analyses of transcriptomics and metagenomics. Twenty-four (12 NX and 12 DLY) at 28 days of age were transported into an experimental house and fed the same
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Dietary geniposide supplementation could enhance hepatic lipid metabolism, immunity, antioxidant capacity, and ammonia stress resistance in turbot (Scophthalmus maximus) Anim. Nutr. (IF 6.1) Pub Date : 2024-12-06 Haoran Sun, Tongtong Yue, Yuqing Hou, Tao Li, Zhi Li, Haiyan Liu, Peiyu Zhang
This study aimed to evaluate the effects of dietary geniposide supplementation on growth performance, lipid metabolism, health status, and ammonia stress resistance in turbot (Scophthalmus maximus). Four hundred fifty fish were randomly allocated into 5 treatments with triplicate tanks (30 fish per tank). They were hand-fed to apparent satiety for 56 d with a basal diet (GP0) or diets containing 100
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Comparison of the effects of taurine and methionine supplementation on the nitrogen metabolism of beef steers elucidated through plasma metabolome profiling Anim. Nutr. (IF 6.1) Pub Date : 2024-12-03 Yufeng Liu, Cheng Liu, Shuo Zhang, Jinming Hu, Meng M. Li, Guangyong Zhao
The objectives of the experiment were to compare the effects of rumen-protected taurine (RPT) and rumen-protected methionine (RPM) on the nitrogen (N) metabolism, plasma biochemical parameters, and metabolomics in beef steers and to clarify whether taurine plays similar roles as methionine (Met) in the regulation of N metabolism in beef steers. Six Simmental steers aged 12 months (liveweight 325 ± 7 kg)
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The impact of combined thymol and rosmarinic acid on the intestinal microbiota and barrier function of the piglets challenged by Escherichia coli K88 Anim. Nutr. (IF 6.1) Pub Date : 2024-12-03 Runlin Li, Xuedong Ding, Mingkang Lei, Panpan Li, Ilias Giannenas, Jing Wang, Weiyun Zhu
It has been found that thymol (Thy) and rosmarinic acid (Ros-A) improve the growth performance of piglets and relieve intestinal inflammation in animals. The effects of Thy and Ros-A separately or in combination (Thy × Ros-A) on the intestinal function and health of piglets challenged with Escherichia coli K88 (E. coli K88) were investigated. A total of 30 piglets aged 21 d were assigned to 5 groups
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Wheat straw and alfalfa hay alone or combined in a high-concentrate diet alters microbial-host interaction in the rumen of lambs Anim. Nutr. (IF 6.1) Pub Date : 2024-11-30 Kefyalew Gebeyew, Hui Mi, Ruiping Du, Min Gao, Diriba Diba, Shaoxun Tang, Zhixiong He, Zhiliang Tan
The inclusion of various forages in a normal forage-to-concentrate ratio has widely been reported to reveal the changes that occur in the foregut tissues. However, the mechanism by which the wheat straw, alfalfa hay, or both alter the orchestrated crosstalk of microbiome and host-transcriptome in the rumen of lambs fed a high-concentrate diet is elusive. Sixty-three Hulunbuir lambs were randomly allotted
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Interaction of dietary replacements of fishmeal by protein blend and feeding frequency on growth performance and protein utilization of gibel carp (Carassius gibelio var. CAS V) Anim. Nutr. (IF 6.1) Pub Date : 2024-11-30 Yongning Yu, Yu Wang, Junyan Jin, Dong Han, Xiaoming Zhu, Haokun Liu, Zhimin Zhang, Yunxia Yang, Shouqi Xie
Feeding frequency represents a potential strategy to improve the utilization of protein sources by fish. This study investigated its impact on the utilization of protein blend in gibel carp. The dietary fishmeal was totally substituted with three protein blends consisting of Tenebrio molitor meal, Chlorella meal, Clostridium autoethanogenum protein, cottonseed protein concentrate, at ratios of 1:1:8:2
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Increased proline intake during gestation alleviates obesity-related impaired fetal development and placental function in gilts Anim. Nutr. (IF 6.1) Pub Date : 2024-11-30 Shuangbo Huang, Jinfeng Li, Hongxuan Ye, Zihao Huang, Junyi Wu, Liudan Liu, Shuo Ma, Hefeng Luo, Tanghong Wei, Kai Liu, Jinping Deng, Dingfa Liu, Chengquan Tan
Maternal proline (Pro) supplementation enhances fetal survival and placental development in mice. However, the effect of Pro on fetal and placental development in gilts remains to be investigated, particularly in the context of obesity-induced impaired pregnancy. Here, we investigated the effect of dietary Pro on fetal and placental development in obese gilts. Exp.1: On day 60 of gestation, 48 gilts
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Enhancing nutrient efficiency through optimizing protein levels in lambs: Involvement of gastrointestinal microbiota Anim. Nutr. (IF 6.1) Pub Date : 2024-11-29 Zhibin Luo, Huimin Ou, Christopher S. McSweeney, Zhiliang Tan, Jinzhen Jiao
Improving the nutrient utilization efficiency of ruminants is of utmost significance for both economic and environmental benefits. Optimizing dietary protein levels represents a key nutritional strategy to enhance ruminant growth performance and reduce nitrogen emissions. In a 63-day experiment, 24 healthy Hulunbuir lambs (initial weight 17.1 ± 2.0 kg, 2.5 months old) were subjected to three treatments:
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Long-term leucine supplementation increases body weight in goats by controlling appetite and muscle protein synthesis under protein-restricted conditions Anim. Nutr. (IF 6.1) Pub Date : 2024-11-29 Xiaokang Lv, Aoyu Jiang, Jinling Hua, Zixin Liu, Qiongxian Yan, Shaoxun Tang, Jinhe Kang, Zhiliang Tan, Jian Wu, Chuanshe Zhou
An inadequate amino acid (AA) supply in animals under protein-restricted conditions can slow skeletal muscle growth. Protein translation can be activated by short-term leucine (Leu) stimulation; however, whether muscle mass increases under long-term Leu supplementation and how the gut and muscle respond to Leu supplementation are largely unknown. In this study, we investigated if muscle mass increases