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Characterization of nsp1 Binding to the Viral RNA Leader Sequence of Severe Acute Respiratory Syndrome Coronavirus Biochemistry (IF 2.9) Pub Date : 2024-05-08 Jonathan L. Cromer, Laurie F. Melton, Kaitlin M. Caughman, Anita Nag
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Identification and Characterization of a Bacterial Periplasmic Solute Binding Protein That Binds l-Amino Acid Amides Biochemistry (IF 2.9) Pub Date : 2024-05-02 Oliver B. Smith, Rebecca L. Frkic, Marina G. Rahman, Colin J. Jackson, Joe A. Kaczmarski
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Elucidation of the Catalytic Sequence of Dihydroorotate Dehydrogenase B from Lactoccocus lactis: Evidence for Accumulation of a Flavin Bisemiquinone State in Catalysis Biochemistry (IF 2.9) Pub Date : 2024-05-01 Corine O. Smith, Graham R. Moran
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Development of Inhibitory Compounds for Metallo-beta-lactamase through Computational Design and Crystallographic Analysis Biochemistry (IF 2.9) Pub Date : 2024-05-01 Taichi Kamo, Keiichi Kuroda, Saki Nimura, Yan Guo, Shota Kondo, Michiyoshi Nukaga, Tyuji Hoshino
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Impact of N-Glycosylation on Protein Structure and Dynamics Linked to Enzymatic C–H Activation in the M. oryzae Lipoxygenase Biochemistry (IF 2.9) Pub Date : 2024-05-01 Chris Whittington, Ajay Sharma, S. Gage Hill, Anthony T. Iavarone, Brian M. Hoffman, Adam R. Offenbacher
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Synthesis of the Carba-Analogs of the α-Pyranose and β-Pyranose Forms of Sedoheptulose 7-Phosphate and Probing the Stereospecificity of Sedoheptulose 7-Phosphate Cyclases Biochemistry (IF 2.9) Pub Date : 2024-04-30 Arash Samadi, Samuel Tanoeyadi, Takeshi Tsunoda, Philip J. Proteau, Taifo Mahmud
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Intermolecular Interactions between Cysteine and Aromatic Amino Acids with a Phenyl Moiety in the DNA-Binding Domain of Heat Shock Factor 1 Regulate Thermal Stress-Induced Trimerization Biochemistry (IF 2.9) Pub Date : 2024-04-30 Chang-Ju Lee, Bo-Hee Choi, So-Sun Kim, David Nahm-Joon Kim, Tae-Hwan Kim, Jeong-Mo Choi, Youngshang Pak, Jang-Su Park
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Insights into Molecular Interactions between a GAPDH-Related Fish Antimicrobial Peptide, Analogs Thereof, and Bacterial Membranes Biochemistry (IF 2.9) Pub Date : 2024-04-29 Samuel Cashman-Kadri, Patrick Lagüe, Muriel Subirade, Ismail Fliss, Lucie Beaulieu
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Photoreversible Aggregation of the Biliprotein Containing the First and Second GAF Domains of a Cyanobacteriochrome All2699 in Nostoc sp. PCC7120 Biochemistry (IF 2.9) Pub Date : 2024-04-29 Min-Li Zhan, Xi Zhao, Xiao-Dan Li, Zi-Zhu Tan, Qian-Zhao Xu, Ming Zhou, Kai-Hong Zhao
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EPR Spin-Trapping for Monitoring Temporal Dynamics of Singlet Oxygen during Photoprotection in Photosynthesis Biochemistry (IF 2.9) Pub Date : 2024-04-28 Collin J. Steen, Jens Niklas, Oleg G. Poluektov, Richard D. Schaller, Graham R. Fleming, Lisa M. Utschig
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NMR Structure of Retinal Guanylate Cyclase Activating Protein 5 (GCAP5) with R22A Mutation That Abolishes Dimerization and Enhances Cyclase Activation Biochemistry (IF 2.9) Pub Date : 2024-04-25 Diana L. Cudia, Effibe O. Ahoulou, Aritra Bej, Annika N. Janssen, Alexander Scholten, Karl-W. Koch, James B. Ames
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Monomeric Esterase: Insights into Cooperative Behavior, Hysteresis/Allokairy Biochemistry (IF 2.9) Pub Date : 2024-04-26 Tania Churasacari Vinces, Anacleto Silva de Souza, Cecília F. Carvalho, Aline Biazola Visnardi, Raphael D. Teixeira, Edgar E. Llontop, Beatriz Aparecida Passos Bismara, Elisabete J. Vicente, José O. Pereira, Robson Francisco de Souza, Mauricio Yonamine, Sandro Roberto Marana, Chuck Shaker Farah, Cristiane R. Guzzo
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Melanoma-Derived DNA Polymerase Theta Variants Exhibit Altered DNA Polymerase Activity Biochemistry (IF 2.9) Pub Date : 2024-04-26 Corey Thomas, Lisbeth Avalos-Irving, Jorge Victorino, Sydney Green, Morgan Andrews, Naisha Rodrigues, Sarah Ebirim, Ayden Mudd, Jamie B. Towle-Weicksel
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Alpha-Synuclein Aggregation Mechanism in the Presence of Nanomaterials Biochemistry (IF 2.9) Pub Date : 2024-04-26 Shahid A. Malik, Somnath Mondal, Hanudatta S. Atreya
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Inositol Hexaphosphate as an Inhibitor and Potential Regulator of p47phox Membrane Anchoring Biochemistry (IF 2.9) Pub Date : 2024-04-26 Angela M. Develin, Brian Fuglestad
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The Chaperone-Active State of HdeB at pH 4 Arises from Its Conformational Rearrangement and Enhanced Stability Instead of Surface Hydrophobicity Biochemistry (IF 2.9) Pub Date : 2024-04-19 Charu Thapliyal, Rajesh Mishra
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Acyl Capping Group Identity Effects on α-Helicity: On the Importance of Amide·Water Hydrogen Bonds to α-Helix Stability Biochemistry (IF 2.9) Pub Date : 2024-04-16 Megh R. Bhatt, Himal K. Ganguly, Neal J. Zondlo
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Stereospecific NANOG PEST Stabilization by Pin1 Biochemistry (IF 2.9) Pub Date : 2024-04-15 Josephine C. Ferreon, Hai Minh Ta, Hyosuk Yun, Kyoung-Jae Choi, My Diem Quan, Phoebe S. Tsoi, Choel Kim, Chul Won Lee, Allan Chris M. Ferreon
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Polyethylene Glycol Impacts Conformation and Dynamics of Escherichia coli Prolyl-tRNA Synthetase Via Crowding and Confinement Effects Biochemistry (IF 2.9) Pub Date : 2024-04-12 Jessica Liebau, Bethany F. Laatsch, Joshua Rusnak, Keegan Gunderson, Brianna Finke, Kassandra Bargender, Alex Narkiewicz-Jodko, Katelyn Weeks, Murphi T. Williams, Irina Shulgina, Karin Musier-Forsyth, Sudeep Bhattacharyya, Sanchita Hati
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Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein Biochemistry (IF 2.9) Pub Date : 2024-04-11 Jianjun Cao, Matthew J. Belousoff, Radostin Danev, Arthur Christopoulos, Denise Wootten, Patrick M. Sexton
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Contribution of a C-Terminal Extension to the Substrate Affinity and Oligomeric Stability of Aldehyde Dehydrogenase from Thermus thermophilus HB27 Biochemistry (IF 2.9) Pub Date : 2024-04-11 Wiktoria Brytan, Kim Shortall, Francisco Duarte, Tewfik Soulimane, Luis Padrela
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Cyanovirin-N Binding to N-Acetyl-d-glucosamine Requires Carbohydrate-Binding Sites on Two Different Protomers Biochemistry (IF 2.9) Pub Date : 2024-04-09 Irene Maier, Georg Kontaxis, Christian Zimmermann, Christoph Steininger
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Substrate Specificities of Variants of Barley (1,3)- and (1,3;1,4)-β-d-Glucanases Resulting from Mutagenesis and Segment Hybridization Biochemistry (IF 2.9) Pub Date : 2024-04-10 Mu-Rong Kao, Jake Parker, Daniel Oehme, Shu-Chieh Chang, Lin-Chen Cheng, Damao Wang, Vaibhav Srivastava, John M. Wagner, Philip J. Harris, Yves S. Y. Hsieh
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4,4-Difluoroproline as a Unique 19F NMR Probe of Proline Conformation Biochemistry (IF 2.9) Pub Date : 2024-04-10 Himal K. Ganguly, Brice A. Ludwig, Caitlin M. Tressler, Megh R. Bhatt, Anil K. Pandey, Caitlin M. Quinn, Shi Bai, Glenn P. A. Yap, Neal J. Zondlo
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Correction to “Structural Elucidation of the Cell-Penetrating Penetratin Peptide in Model Membranes at the Atomic Level: Probing Hydrophobic Interactions in the Blood–Brain Barrier” Biochemistry (IF 2.9) Pub Date : 2024-04-10 Swapna Bera, Rajiv K. Kar, Susanta Mondal, Kalipada Pahan, Anirban Bhunia
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Modulation of Electron Transfer Branches by Atrazine and Triazine Herbicides in Photosynthetic Reaction Centers Biochemistry (IF 2.9) Pub Date : 2024-04-08 Gai Nishikawa, Keisuke Saito, Hiroshi Ishikita
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Initial Steps in Methanobactin Biosynthesis: Substrate Binding by the Mixed-Valent Diiron Enzyme MbnBC Biochemistry (IF 2.9) Pub Date : 2024-04-08 Richard J. Jodts, Madeline B. Ho, Reyvin M. Reyes, Yun Ji Park, Peter E. Doan, Amy C. Rosenzweig, Brian M. Hoffman
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Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme Biochemistry (IF 2.9) Pub Date : 2024-04-05 Shramana Chatterjee, Matthias Fellner, JoelA. Rankin, Midhun G. Thomas, Simahudeen Bathir J S Rifayee, Christo Z. Christov, Jian Hu, Robert P. Hausinger
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Differential Interactions of the Proteasome Inhibitor PI31 with Constitutive and Immuno-20S Proteasomes Biochemistry (IF 2.9) Pub Date : 2024-04-05 Jason Wang, Abbey Kjellgren, George N. DeMartino
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Strong Protection by 4-Hydroxyestrone against Erastin-Induced Ferroptotic Cell Death in Estrogen Receptor-Negative Human Breast Cancer Cells: Evidence for Protein Disulfide Isomerase as a Mechanistic Target for Protection Biochemistry (IF 2.9) Pub Date : 2024-04-03 Hongge Wang, Ming-Jie Hou, Lixi Liao, Peng Li, Tongxiang Chen, Pan Wang, Bao Ting Zhu
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Kinetics of Intermediate Release Enhances P450 11B2-Catalyzed Aldosterone Synthesis Biochemistry (IF 2.9) Pub Date : 2024-04-02 Juan Valentín-Goyco, Sang-Choul Im, Richard J. Auchus
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Glycerol 3-Phosphate Dehydrogenase: Role of the Protein Conformational Change in Activation of a Readily Reversible Enzyme-Catalyzed Hydride Transfer Reaction Biochemistry (IF 2.9) Pub Date : 2024-03-28 Judith R. Cristobal, Rania Hegazy, John P. Richard
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Drug Design: Do Not Forget the Supramolecular Factor Biochemistry (IF 2.9) Pub Date : 2024-03-28 Steven L. Regen
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Poacic Acid, a Plant-Derived Stilbenoid, Augments Cell Wall Chitin Production, but Its Antifungal Activity Is Hindered by This Polysaccharide and by Fungal Essential Metals Biochemistry (IF 2.9) Pub Date : 2024-03-27 Adi Yona, Micha Fridman
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Replication of [AT/TA]25 Microsatellite Sequences by Human DNA Polymerase δ Holoenzymes Is Dependent on dNTP and RPA Levels Biochemistry (IF 2.9) Pub Date : 2024-03-26 Kara G. Pytko, Rachel L. Dannenberg, Kristin A. Eckert, Mark Hedglin
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In Vitro and In Silico Explorations of the Protein Conformational Changes of Corynebacterium glutamicum MshA, a Model Retaining GT-B Glycosyltransferase Biochemistry (IF 2.9) Pub Date : 2024-03-20 Bakar A. Hassan, Jozafina Milicaj, Meka Tyson, Ramesh Karki, Yuk Y. Sham, Patrick A. Frantom, Erika A. Taylor
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Cryo-EM of the Nucleosome Core Particle Bound to Ran-RCC1 Reveals a Dynamic Complex Biochemistry (IF 2.9) Pub Date : 2024-03-19 Shuya Kate Huang, John L. Rubinstein, Lewis E. Kay
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Tryptophan-Centric Bioinformatics Identifies New Lasso Peptide Modifications Biochemistry (IF 2.9) Pub Date : 2024-03-18 Lonnie A. Harris, Hamada Saad, Kyle E. Shelton, Lingyang Zhu, Xiaorui Guo, Douglas A. Mitchell
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AQP4-DARPin1: A Chimeric Antigen Based on Scaffold Protein DARPin for Efficient Detection of AQP4-IgG in NMOSD Biochemistry (IF 2.9) Pub Date : 2024-03-18 Xiaofei Wang, Shubei Ma, Ying Bai, Xinyang Wu, Fangling Ji, Lingyun Jia
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Defining Requirements for Heme Binding in PGRMC1 and Identifying Key Elements that Influence Protein Dimerization Biochemistry (IF 2.9) Pub Date : 2024-03-15 Prajakta Badve, Katlyn K. Meier
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Structural Motifs at the Telomeres and Their Role in Regulatory Pathways Biochemistry (IF 2.9) Pub Date : 2024-03-14 Abeer F R Alanazi, Gary N Parkinson, Shozeb Haider
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Characterization of a Structurally Distinct ATP-Dependent Reactivating Factor of Adenosylcobalamin-Dependent Lysine 5,6-Aminomutase Biochemistry (IF 2.9) Pub Date : 2024-03-12 Amanda L. Darbyshire, Kirsten R. Wolthers
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Correction to “Non-Steady State Analysis of Enzyme Kinetics in Real Time Elucidates Substrate Association and Dissociation Rates: Demonstration with Analysis of Firefly Luciferase Mutants” Biochemistry (IF 2.9) Pub Date : 2024-03-12 Renee Dale, Yuki Ohmuro-Matsuyama, Hiroshi Ueda, Naohiro Kato
Some of the numerical values presented in Supplemental File S2 were wrong. The corrected Supporting Information is with this Correction. The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.biochem.3c00657. Corrected Supplemental File S2 (PDF) Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may
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Structure–Function Analysis of the A1 Subunit of Shiga Toxin 2 with Peptides That Target the P-Stalk Binding Site and Inhibit Activity Biochemistry (IF 2.9) Pub Date : 2024-03-11 Xiao-Ping Li, Michael J. Rudolph, Yang Chen, Nilgun E. Tumer
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RaptGen-Assisted Generation of an RNA/DNA Hybrid Aptamer against SARS-CoV-2 Spike Protein Biochemistry (IF 2.9) Pub Date : 2024-03-08 Tatsuo Adachi, Shigetaka Nakamura, Akiya Michishita, Daiki Kawahara, Mizuki Yamamoto, Michiaki Hamada, Yoshikazu Nakamura
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Glu1022.53-Mediated Early Conformational Changes in the Process of Light-Induced Green Cone Pigment Activation Biochemistry (IF 2.9) Pub Date : 2024-03-08 Takuma Sasaki, Kota Katayama, Hiroo Imai, Hideki Kandori
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Binding and Activation of LRP1-Dependent Cell Signaling in Schwann Cells Using a Peptide Derived from the Hemopexin Domain of MMP-9 Biochemistry (IF 2.9) Pub Date : 2024-03-07 John H. Kim, Aashish Shivkumar, Masaki Norimoto, Sascha Castro Lingl, Christian Seitz, Rommie E. Amaro, Steve L. Gonias, Jerry Yang, Wendy M. Campana
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Assessing Interferon Regulatory Factor 4 Complex Formation: Differential Behavior of Homocomplexes Versus Heterocomplexes Induced by Mutations Biochemistry (IF 2.9) Pub Date : 2024-03-05 Yupeng Li, Setoka Hirano, Katsuya Sato, Masatake Osawa, Hitoshi Nagaoka
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Lipid-Binding Regions within PKC-Related Serine/Threonine Protein Kinase N1 (PKN1) Required for Its Regulation Biochemistry (IF 2.9) Pub Date : 2024-03-05 Jason L. J. Lin, Hanna S. Yuan
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Zα Domain of ADAR1 Binds to an A-Form-like Nucleic Acid Duplex with Low Micromolar Affinity Biochemistry (IF 2.9) Pub Date : 2024-03-04 Parker J. Nichols, Robb Welty, Jeffrey B. Krall, Morkos A. Henen, Quentin Vicens, Beat Vögeli
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Discovery of Red-Shifting Mutations in Firefly Luciferase Using High-Throughput Biochemistry Biochemistry (IF 2.9) Pub Date : 2024-03-04 Clair M. Colee, Nicole M. Oberlag, Marcell Simon, Owen S. Chapman, Lyndsey C. Flanagan, Edison S. Reid-McLaughlin, Jordan A. Gewing-Mullins, Synaida Maiche, Devi F. Patel, Andre R. O. Cavalcanti, Aaron M. Leconte
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A Novel Dual-Fc Bispecific Antibody with Enhanced Fc Effector Function Biochemistry (IF 2.9) Pub Date : 2024-03-01 Fulai Zhou, Yinyin Ben, Hao Jiang, Siwen Tan, Guangmao Mu, Zhengxia Zha, Shuting Dong, Sheng Huang, Yijun Zhou, Ying Jin, Mark L. Chiu
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QM/MM Study of the Catalytic Mechanism and Substrate Specificity of the Aromatic Substrate C-Methyltransferase Fur6 Biochemistry (IF 2.9) Pub Date : 2024-02-29 Fan Zhao, Yoshitaka Moriwaki, Tomohiro Noguchi, Kentaro Shimizu, Tomohisa Kuzuyama, Tohru Terada
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Structure-Based Engineering of a Sesquiterpene Cyclase to Generate an Alcohol Product: Conversion of epi-Isozizaene Synthase into α-Bisabolol Synthase Biochemistry (IF 2.9) Pub Date : 2024-02-29 Samuel A. Eaton, David W. Christianson
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Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase Biochemistry (IF 2.9) Pub Date : 2024-02-28 Huiying Li, Christine D. Hardy, Cory T. Reidl, Qing Jing, Fengtian Xue, Maris Cinelli, Richard B. Silverman, Thomas L. Poulos
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Replication Bypass of the N-(2-Deoxy-d-erythro-pentofuranosyl)-urea DNA Lesion by Human DNA Polymerase η Biochemistry (IF 2.9) Pub Date : 2024-02-27 Rachana Tomar, Songlin Li, Martin Egli, Michael P. Stone
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Disruption of an Active Site Network Leads to Activation of C2α-Lactylthiamin Diphosphate on the Antibacterial Target 1-Deoxy-d-xylulose-5-phosphate Synthase Biochemistry (IF 2.9) Pub Date : 2024-02-23 Eucolona M. Toci, Steven L. Austin, Ananya Majumdar, H. Lee Woodcock, Caren L. Freel Meyers
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Pronucleotide Probes Reveal a Diverging Specificity for AMPylation vs UMPylation of Human and Bacterial Nucleotide Transferases Biochemistry (IF 2.9) Pub Date : 2024-02-22 Dietrich Mostert, Wilhelm Andrei Bubeneck, Theresa Rauh, Pavel Kielkowski, Aymelt Itzen, Kirsten Jung, Stephan A. Sieber
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Characterization of the Zinc Uptake Repressor (Zur) from Acinetobacter baumannii Biochemistry (IF 2.9) Pub Date : 2024-02-22 Minyong Kim, My Tra Le, Lixin Fan, Courtney Campbell, Sambuddha Sen, Daiana A. Capdevila, Timothy L. Stemmler, David P. Giedroc
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Biosynthesis of Cytidine Diphosphate-6-d-Glucitol for the Capsular Polysaccharides of Campylobacter jejuni Biochemistry (IF 2.9) Pub Date : 2024-02-22 Manas K. Ghosh, Tamari Narindoshvili, James B. Thoden, Mitchell E. Schumann, Hazel M. Holden, Frank M. Raushel