DNA storage offers substantial information density1-7 and exceptional half-life3. We devised a 'DNA-of-things' (DoT) storage architecture to produce materials with immutable memory. In a DoT framework, DNA molecules record the data, and these molecules are then encapsulated in nanometer silica beads8, which are fused into various materials that are used to print or cast objects in any shape. First, we applied DoT to three-dimensionally print a Stanford Bunny9 that contained a 45 kB digital DNA blueprint for its synthesis. We synthesized five generations of the bunny, each from the memory of the previous generation without additional DNA synthesis or degradation of information. To test the scalability of DoT, we stored a 1.4 MB video in DNA in plexiglass spectacle lenses and retrieved it by excising a tiny piece of the plexiglass and sequencing the embedded DNA. DoT could be applied to store electronic health records in medical implants, to hide data in everyday objects (steganography) and to manufacture objects containing their own blueprint. It may also facilitate the development of self-replicating machines.

中文翻译：

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一种 DNA-of-thing 存储架构，用于创建具有嵌入式内存的材料。

DNA 存储提供了大量的信息密度 1-7 和特殊的半衰期 3。我们设计了一种“DNA-of-things”（DoT）存储架构来生产具有不可变记忆的材料。在 DoT 框架中，DNA 分子记录数据，然后这些分子被封装在纳米二氧化硅珠中 8，然后融合成各种材料，用于打印或铸造任何形状的物体。首先，我们应用 DoT 来 3D 打印斯坦福 Bunny9，其中包含用于合成的 45 kB 数字 DNA 蓝图。我们合成了五代兔子，每一代都来自上一代的记忆，没有额外的 DNA 合成或信息降解。为了测试 DoT 的可扩展性，我们存储了一个 1。4 MB 的有机玻璃眼镜片 DNA 视频，并通过切下一小块有机玻璃并对嵌入的 DNA 进行测序来检索它。DoT 可用于在医疗植入物中存储电子健康记录，在日常物品中隐藏数据（隐写术）以及制造包含自己蓝图的物品。它还可以促进自我复制机器的发展。