The organic electronic ion pump (OEIP) is an emerging bioelectronic technology for on-demand and local delivery of pharmacologically active species, especially targeting alkali ions, and neurotransmitters. While electrical control is advantageous for providing precise spatial, temporal, and quantitative delivery, traditionally, it necessitates wiring. This complicates implantation. Herein, we demonstrate integration of an OEIP with a photovoltaic driver on a flexible carrier, which can be addressed by red light within the tissue transparency window. Organic thin-film bilayer photovoltaic pixels are arranged in series and/or vertical tandem to provide the 2.5–4.5 V necessary for operating the high-resistance electrophoretic ion pumps. We demonstrate light-stimulated transport of cations, ranging in size from protons to acetylcholine. The device, laminated on top of the skin, can easily be driven with a red LED emitting through a 1.5-cm-thick finger. The end result of our work is a thin and flexible integrated wireless device platform.

有机电子离子泵（OEIP）是一种新兴的生物电子技术，用于按需和局部递送药理活性物质，尤其是针对碱金属离子和神经递质的物质。尽管电气控制有利于提供精确的空间，时间和定量传递，但传统上它需要接线。这使植入变得复杂。在本文中，我们演示了OEIP与光伏驱动器在柔性载体上的集成，可以通过组织透明窗口内的红光解决该问题。有机薄膜双层光伏像素串联和/或垂直串联排列，以提供操作高电阻电泳离子泵所需的2.5-4.5V。我们展示了光刺激的阳离子运输，大小从质子到乙酰胆碱不等。装置，层压在皮肤顶部的红色LED可以很容易地通过1.5厘米厚的手指发出的光来驱动。我们工作的最终结果是一个薄而灵活的集成无线设备平台。