Purpose

Evaluation of the impact of catheter ablation for ventricular extrasystoles (VES) in structurally normal hearts on quality of life (QOL) and symptomatology.

Methods

Symptom analysis assessed with a disease-specific questionnaire, EHRA score for AF, and QOL analysis at baseline and 1 year after ablation.

Results

The study enrolled 39 patients between April 2016 and November 2019. Two patients were excluded from further analysis. At baseline, palpitations were reported in 31/37 (84%); syncope in 12/37 (32%); other cardiac symptoms in 33/37 (89%) of patients. The EHRA score was 3 or 4 in 13 patients (35%). With the modified arrhythmia-specific questionnaire (MASQ) psychological and physical scores were 46 and 39%. The overall perception of health in the SF-36 was 56 ± 16%. Ablation was performed in 35/37 (95%). At regular follow-up, symptoms were reported in 14/37 (38%) patients. ECG suggested a good procedural outcome in 65% with VES burden on Holter < 1% in 68%. At follow-up, palpitations were reported in 61% (P < 0.07); syncope in only 1 patient (P < 0.05). The EHRA score was 3 or 4 in only one patient (P < 0.05). MASQ scores improved to 62 and 60% (both p < 0.001). The overall perception of health in the SF-36 became 64 ± 17% (P < 0.02).

Conclusions

Patients with VES suffer from a wide variety of symptoms and have a low quality of life, as demonstrated by the EHRA score and conventional questionnaires. After catheter ablation, palpitations are still reported, but become less frequently present. Syncope becomes rare. Quality of life improves significantly from all perspectives.

中文翻译：

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选择接受室性期前收缩消融的患者的生活质量和症状：一项前瞻性研究

目的

评估导管消融治疗结构正常心脏的室性期外收缩 (VES) 对生活质量 (QOL) 和症状的影响。

方法

症状分析通过疾病特异性问卷、AF 的 EHRA 评分以及基线和消融后 1 年的 QOL 分析进行评估。

结果

该研究在 2016 年 4 月至 2019 年 11 月期间招募了 39 名患者。 两名患者被排除在进一步分析之外。在基线时，心悸报告率为 31/37 (84%)；晕厥 12/37 (32%); 33/37 (89%) 的患者出现其他心脏症状。13 名患者 (35%) 的 EHRA 评分为 3 或 4。使用改良的心律失常特定问卷 (MASQ) 的心理和身体评分分别为 46% 和 39%。SF-36 的整体健康感为 56 ± 16%。35/37 (95%) 进行消融。在定期随访中，14/37 (38%) 的患者报告了症状。心电图显示 65% 的手术结果良好，68% 的 Holter 上 VES 负担 < 1%。随访时，有 61% 报告出现心悸（P  < 0.07）；仅 1 例患者出现晕厥（P < 0.05)。仅一名患者的 EHRA 评分为 3 或 4（P  < 0.05）。MASQ 分数提高到 62% 和 60%（均p  < 0.001）。SF-36 对健康的总体看法变为 64 ± 17% ( P  < 0.02)。

结论

正如 EHRA 评分和常规问卷所证明的那样，VES 患者患有多种症状并且生活质量低下。导管消融后，仍有心悸的报道，但出现频率降低。晕厥变得罕见。从各个角度来看，生活质量都显着提高。