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TYGS and LPSN: a database tandem for fast and reliable genome-based classification and nomenclature of prokaryotes
Nucleic Acids Research ( IF 16.6 ) Pub Date : 2021-09-22 , DOI: 10.1093/nar/gkab902
Jan P Meier-Kolthoff 1 , Joaquim Sardà Carbasse 1 , Rosa L Peinado-Olarte 1 , Markus Göker 1
Affiliation  

Microbial systematics is heavily influenced by genome-based methods and challenged by an ever increasing number of taxon names and associated sequences in public data repositories. This poses a challenge for database systems, particularly since it is obviously advantageous if such data are based on a globally recognized approach to manage names, such as the International Code of Nomenclature of Prokaryotes. The amount of data can only be handled if accurate and reliable high-throughput platforms are available that are able to both comply with this demand and to keep track of all changes in an efficient and flexible way. The List of Prokaryotic names with Standing in Nomenclature (LPSN) is an expert-curated authoritative resource for prokaryotic nomenclature and is available at https://lpsn.dsmz.de. The Type (Strain) Genome Server (TYGS) is a high-throughput platform for accurate genome-based taxonomy and is available at https://tygs.dsmz.de. We here present important updates of these two previously introduced, heavily interconnected platforms for taxonomic nomenclature and classification, including new high-level facilities providing access to bioinformatic algorithms, a considerable expansion of the database content, and new ways to easily access the data.

中文翻译:

TYGS 和 LPSN:用于快速可靠的基于基因组的原核生物分类和命名的数据库串联

微生物系统学深受基于基因组的方法的影响,并受到公共数据库中越来越多的分类单元名称和相关序列的挑战。这对数据库系统提出了挑战,特别是因为如果此类数据基于全球公认的名称管理方法,例如国际原核生物命名法,显然是有利的。只有在能够满足这一需求并以高效灵活的方式跟踪所有变化的准确可靠的高吞吐量平台可用时,才能处理大量数据。原核生物命名列表 (LPSN) 是专家策划的原核生物命名权威资源,可在 https://lpsn.dsmz.de 获取。Type (Strain) Genome Server (TYGS) 是一个高通量平台,可用于准确的基于基因组的分类,可在 https://tygs.dsmz.de 获得。我们在这里介绍了这两个先前引入的、高度互联的分类命名和分类平台的重要更新,包括提供对生物信息学算法的访问的新的高级设施、数据库内容的显着扩展以及轻松访问数据的新方法。
更新日期:2021-09-22
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