ABSTRACT

There has not been a significant improvement in the rate of clinical trial accrual in more than 20 years. Worse, the challenge of inadequate representation among racial and ethnic minorities also persists, deepening disparities in health. Community-Based Participatory Research (CBPR) is a participatory communication method that centers on effective dialogue between researchers and community stakeholders with the goal of creating an equitable partnership for health and social change. The objective of the current study was to provide an update since a systematic review in 2012, on the current status of the empirical research, with a particular focus on the elements of CBPR methods used to improve the rate of accrual of members of racial and ethnic minority communities for clinical trials. Our systematic review found a large increase in the number of CBPR related studies and studies related to racial and ethnic representation in research. More than 85% of studies employing CBPR methods saw statistically positive outcomes. Specifically, the elements of CBPR that are associated with these positive outcomes include community partner participation in (1) a study advisory committee, (2) data collection, (3) the development of interventions, and (4) participant recruitment. However, the results of our study indicate that researchers need to be more transparent about the extent of community participation as well as more thoroughly and accurately describe the nature of the partnership with members of minority communities in order to build upon the scientific literature on community-engaged methods.

摘要

20多年来，临床试验的应计率没有显着提高。更糟糕的是，少数族裔和少数族裔代表不足的挑战也依然存在，加剧了健康差距。基于社区的参与式研究 (CBPR) 是一种参与式交流方法，以研究人员和社区利益相关者之间的有效对话为中心，旨在为健康和社会变革建立公平的伙伴关系。本研究的目的是提供自 2012 年系统评价以来实证研究现状的更新，特别关注用于提高种族和民族成员应计率的 CBPR 方法的要素少数民族社区进行临床试验。我们的系统回顾发现 CBPR 相关研究和研究中与种族和民族代表性相关的研究数量大幅增加。超过 85% 的采用 CBPR 方法的研究在统计学上看到了积极的结果。具体而言，与这些积极成果相关的 CBPR 要素包括社区合作伙伴参与 (1) 研究咨询委员会，(2) 数据收集，(3) 干预措施的制定，以及 (4) 参与者招募。然而，我们的研究结果表明，研究人员需要更加透明地了解社区参与的程度，并更彻底、更准确地描述与少数族裔社区成员合作的性质，以便在关于社区的科学文献的基础上再接再厉——参与的方法。