Purpose: The implantation of a gastric balloon (also known as intragastric balloon) is an established and reversible endoscopic procedure for adiposity therapy. Structural changes of the stomach wall are expected to occur with gastric balloon implantation; however, until now these changes have rarely been investigated. Methods: We compared the histological structure of the stomach wall after gastric-sleeve resection in a group of patients following gastric balloon implantation and a group without previous gastric balloon implantation. Results: Following gastric balloon implantation, the tunica muscularis was found to be significantly thicker than without gastric balloon implantation. The enlarging of the tunica muscularis is not caused by hyperplasia of the leiomyocytes, but by hypertrophy of the leiomyocytes and an increase in collagen fibers (fibrosis). Conclusion: A longer-lasting hypertrophy of the tunica muscularis, particularly in the corpus, should be taken into account when surgical treatment follows gastric balloon implantation. The staple suture height should be adjusted to the altered tissue composition since reduced tissue elasticity must be expected due to fibrosis.
Visc Med

中文翻译：

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胃球囊植入作为病态肥胖治疗的一部分改变了胃壁的结构

目的：胃球囊（也称为胃内球囊）的植入是一种成熟且可逆的内窥镜治疗肥胖症的方法。胃壁的结构变化预计会随着胃球囊植入而发生；然而，到目前为止，这些变化很少被研究。方法：我们比较了一组胃球囊植入术后患者和一组既往未植入胃球囊患者的胃袖状切除术后胃壁的组织学结构。结果：胃球囊植入后，发现肌层比没有胃球囊植入时明显更厚。肌层的扩大不是由平滑肌细胞增生引起的，而是由平滑肌细胞肥大和胶原纤维增加（纤维化）引起的。结论：当胃球囊植入后进行手术治疗时，应考虑肌层持续肥大，特别是在体中。由于纤维化导致组织弹性降低，因此应根据改变的组织成分调整缝合线高度。
粘性医学