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Stability of psilocybin and its four analogs in the biomass of the psychotropic mushroom Psilocybe cubensis
Drug Testing and Analysis ( IF 2.9 ) Pub Date : 2020-10-29 , DOI: 10.1002/dta.2950
Klára Gotvaldová 1 , Kateřina Hájková 1, 2 , Jan Borovička 3, 4 , Radek Jurok 1, 2, 5 , Petra Cihlářová 1, 2 , Martin Kuchař 1, 6
Affiliation  

Psilocybin, psilocin, baeocystin, norbaeocystin, and aeruginascin are tryptamines structurally similar to the neurotransmitter serotonin. Psilocybin and its pharmacologically active metabolite psilocin in particular are known for their psychoactive effects. These substances typically occur in most species of the genus Psilocybe (Fungi, Strophariaceae). Even the sclerotia of some of these fungi known as “magic truffles” are of growing interest in microdosing due to them improving cognitive function studies. In addition to microdosing studies, psilocybin has also been applied in clinical studies, but only its pure form has been administrated so far. Moreover, the determination of tryptamine alkaloids is used in forensic analysis.

中文翻译:

psilocybin 及其四种类似物在精神蘑菇 Psilocybe cubensis 生物量中的稳定性

裸盖菇素、裸盖菇素、赤霉毒素、去甲藻毒素和绿脓杆菌素是结构上与神经递质血清素相似的色胺。裸盖菇素及其药理活性代谢物裸盖菇素以其精神活性作用而闻名。这些物质通常存在于大多数Psilocybe属(真菌、球果科)中。甚至一些被称为“神奇松露”的真菌的菌核也对微剂量给药越来越感兴趣,因为它们可以改善认知功能研究。除了微剂量研究外,裸盖菇素也已应用于临床研究,但迄今为止仅以纯形式给药。此外,色胺生物碱的测定用于法医分析。
更新日期:2020-10-29
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