Biocompatible magnetic nanoparticle-mediated magnetic hyperthermia is an innovative, efficient, and safer thermo-therapeutic approach for cancer treatment. Structural and magnetic properties of magnetic nanoparticles as well as external magnetic field parameters are responsible for a controlled heating performance imperative for clinical success. This review covers topics from the nanophysics of magnetic nanoparticles through the basic concepts of magnetism to the different magnetic nanoparticles used for magnetic hyperthermia. Relevant properties beneficial for magnetic hyperthermia including size (nanosize regime of 10–100 nm), shape (anisotropic and isotropic), viscosity of the dispersive medium, and applied magnetic field parameters to optimize the heat dissipation via various mechanisms are also addressed. Primary aim of the present review is to provide an interdisciplinary knowledge platform for the basic understanding of nanomagnetism in order to advance further in the field of nanomedicine. This review pinpoints recent advancements in nanoparticle-tumor tissue interactions and their translation to clinical applications. The present review differs from other contemporary reviews by reporting the up-to-date developments in the nanotechnology aspects of magnetic hyperthermia and addressing the future perspectives.

生物相容性磁性纳米粒子介导的磁热疗是一种创新，有效且安全的热疗法，可用于癌症治疗。磁性纳米颗粒的结构和磁性以及外部磁场参数是控制加热性能的关键，这对于临床成功至关重要。这篇综述涵盖了从磁性纳米粒子的纳米物理学到磁性的基本概念，再到用于磁性热疗的不同磁性纳米粒子的主题。还讨论了有益于磁热疗的相关属性，包括尺寸（10-100 nm的纳米尺寸范围），形状（各向异性和各向同性），分散介质的粘度以及通过各种机制优化散热的外加磁场参数。本综述的主要目的是为纳米磁性的基本理解提供一个跨学科的知识平台，以便在纳米医学领域进一步发展。这篇综述指出了纳米粒子与肿瘤组织相互作用的最新进展及其在临床上的应用。本综述与其他当代综述不同，它报告了磁热疗纳米技术方面的最新发展并探讨了未来的前景。