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Synthetic Access to Cannabidiol and Analogs as Active Pharmaceutical Ingredients.
Journal of Medicinal Chemistry ( IF 7.3 ) Pub Date : 2020-06-12 , DOI: 10.1021/acs.jmedchem.0c00095
Michael C Pirrung 1, 2
Affiliation  

Cannabinoids have surely been one of the most widely self-administered drugs other than caffeine. The U.S. FDA recently approved one cannabinoid-based drug whose active pharmaceutical ingredient (API) is cannabidiol (CBD). The long history of individual use of cannabis for a wide range of conditions has sparked great interest in other uses of CBD, in ethical drugs and botanical supplements as well as in foods and nonprescription wellness products. CBD may be sourced from cannabis plants but can also be prepared synthetically, the topic of this review.

中文翻译:

合成获取卡纳比多二醇和类似物作为活性药物成分。

大麻素肯定是除咖啡因以外最广泛的自我管理药物之一。美国FDA最近批准了一种基于大麻素的药物,其活性药物成分(API)为大麻二酚(CBD)。个人在各种情况下广泛使用大麻的悠久历史引起了人们对CBD的其他用途,伦理药物和植物补品以及食品和非处方保健产品的极大兴趣。CBD可能来自大麻植物,但也可以合成制备,这是本综述的主题。
更新日期:2020-06-12
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