Wound healing is a highly regulated process composed of four overlapping phases: (1) coagulation/haemostasis, (2) inflammation, (3) proliferation and (4) remodelling. Comorbidities such as advanced age, diabetes and obesity can impair natural tissue repair, rendering the wound in a pathological state of inflammation. This results in significant discomfort for patients and considerable financial costs for healthcare systems. Due to the complex nature of wound healing, current treatments are ineffective at dealing with delayed healing. With flexible properties that can be tailored, nanomaterials have emerged as alternative therapeutics for many biomedical applications. A nanofibrous network can be made via electrospinning polymers using a high electric field to create a responsive meshwork that can be used as a medical dressing. A nanofibrous device has properties that can overcome the limitations of traditional dressings, such as: (1) adaptability to wound contour; (2) controlled drug delivery of therapeutics; (3) gaseous exchange; (4) exudate absorption and (5) surface functionalisation to further enhance the biological activity of the dressing. This review details emerging trends in nanotechnology to specifically target wound healing applications. Particular focus is given to the most common natural polymers that could address many unmet healthcare needs.

伤口愈合是一个高度受控的过程，包括四个重叠阶段：（1）凝固/止血，（2）炎症，（3）增殖和（4）重塑。高龄，糖尿病和肥胖症等合并症会损害自然组织的修复，使伤口处于炎症的病理状态。这给患者带来极大的不适感，并给医疗保健系统带来可观的财务成本。由于伤口愈合的复杂性质，当前的治疗方法在延迟愈合方面无效。纳米材料具有可定制的灵活特性，已成为许多生物医学应用的替代疗法。可以通过使用高电场对聚合物进行静电纺丝来制造纳米纤维网络，以形成可以用作医疗敷料的响应性网状结构。纳米纤维装置的特性可以克服传统敷料的局限性，例如：（1）对伤口轮廓的适应性；（2）控制药物的药物输送；（三）气体交换；（4）渗出液的吸收和（5）表面功能化，以进一步增强敷料的生物活性。这篇综述详细介绍了纳米技术针对伤口愈合应用的新兴趋势。特别关注可以解决许多未满足的医疗保健需求的最常见的天然聚合物。这篇综述详细介绍了纳米技术针对伤口愈合应用的新兴趋势。特别关注可以解决许多未满足的医疗保健需求的最常见的天然聚合物。这篇综述详细介绍了纳米技术针对伤口愈合应用的新兴趋势。特别关注可以解决许多未满足的医疗保健需求的最常见的天然聚合物。