Catalytic reductive coupling of enone, acrylate, or vinyl heteroaromatic pronucleophiles with carbonyl or imine partners offers an alternative to base-mediated enolization in aldol- and Mannich-type reactions. In this review, direct catalytic reductive aldol and Mannich reactions are exhaustively catalogued on the basis of metal or organocatalyst. Stepwise processes involving enone conjugate reduction to form discrete enol or (metallo)enolate derivatives followed by introduction of carbonyl or imine electrophiles and aldol reactions initiated via enone conjugate addition are not covered.

中文翻译：

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烯酮，丙烯酸酯和乙烯基杂芳族原核亲核试剂的催化还原性羟醛和曼尼希反应。

烯酮，丙烯酸酯或乙烯基杂芳族亲核试剂与羰基或亚胺配偶体的催化还原偶联为醛醇和曼尼希型反应中碱介导的烯醇化提供了一种替代方法。在这篇综述中，直接催化还原性羟醛和曼尼希反应是根据金属或有机催化剂详尽地分类的。涉及烯键共轭物还原以形成不连续的烯醇或（金属）烯酸酯衍生物，随后引入羰基或亚胺亲电试剂以及通过烯键共轭物加成引发的醛醇缩合反应的分步方法未涵盖。