The rapid growth of research in the areas of chemical and biochemical sensors, lab-on-a-chip, mobile technology, and wearable electronics offers an unprecedented opportunity in the development of mobile and wearable point-of-care testing (POCT) systems for self-testing. Successful implementation of such POCT technologies leads to minimal user intervention during operation to reduce user errors; user-friendly, easy-to-use and simple detection platforms; high diagnostic sensitivity and specificity; immediate clinical assessment; and low manufacturing and consumables costs. In this review, we discuss recent developments in the field of highly integrated mobile and wearable POCT systems. In particular, aspects of sample handling platforms, recognition elements and sensing methods, and new materials for signal transducers and powering devices for integration into mobile or wearable POCT systems will be highlighted. We also summarize current challenges and future prospects for providing personal healthcare with sample-in result-out mobile and wearable POCT.

中文翻译：

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完全集成的移动和可穿戴式即时检验系统自测试的最新进展，挑战和前景。

在化学和生化传感器，芯片实验室，移动技术和可穿戴电子产品领域的研究的快速增长为开发用于移动和可穿戴医疗点测试（POCT）系统的空前机遇提供了机会自检。此类POCT技术的成功实施可在操作过程中将用户干预降至最低，从而减少用户错误。用户友好，易于使用和简单的检测平台；高诊断灵敏度和特异性；立即临床评估；以及较低的制造和耗材成本。在这篇评论中，我们讨论了高度集成的移动和可穿戴POCT系统领域的最新发展。特别是样本处理平台，识别元素和感应方法的各个方面，并将重点介绍用于集成到移动或可穿戴式POCT系统中的信号传感器和供电设备的新材料。我们还总结了为个人医疗保健提供样品输入输出的移动和可穿戴式POCT的当前挑战和未来前景。