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Plant-based vaccines for Alzheimer's disease.
Proceedings of the Japan Academy, Series B ( IF 3.1 ) Pub Date : 2019-01-01 , DOI: 10.2183/pjab.95.020
Shoichi Ishiura 1 , Taiji Yoshida 2
Affiliation  

Alzheimer's disease (AD) is one of the major causes of chronic and progressive cognitive decline, with the pathological hallmarks of senile plaques and neurofibrillary tangles. Amyloid β peptide (Aβ) is the main component of senile plaques, and the pathological load of Aβ in the brain has been shown to be a marker of the severity of AD. To prevent the accumulation of plaques, novel and safer plant-based vaccine strategies have been suggested. In this review, we summarize the results of plant vaccines against Aβ.

中文翻译:

用于阿尔茨海默病的植物疫苗。

阿尔茨海默病(AD)是慢性进行性认知能力下降的主要原因之一,其病理特征是老年斑和神经原纤维缠结。β淀粉样肽(Aβ)是老年斑的主要成分,脑内Aβ的病理负荷已被证明是AD严重程度的标志。为了防止斑块积聚,人们提出了新颖且更安全的植物疫苗策略。在这篇综述中,我们总结了 Aβ 植物疫苗的结果。
更新日期:2019-11-01
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