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成果及论文

Publication List 2021

62. Design, Synthesis and Biological Evaluation of N-anthraniloyl Tryptamine Derivatives as Pleiotropic Molecules for the Therapy of Malignant Glioma

European Journal of Medicinal Chemistry 2021, [DOI:10.1016/j.ejmech.2021.113564]


61. Discovery of a novel inhibitor of nitric oxide production with potential therapeutic effect on acute inflammation

Bioorganic & Medicinal Chemistry Letters 2021, [DOI:10.1016/j.bmcl.2021.128106]


60. Swainsonine producing performance of Alternaria oxytropis was improved by Heavy-ion mutagenesis technology.

FEMS Microbiology Letters. 2021, [DOI:10.1093/femsle/fnab047]



59. Synthesis of an isomer of lycoplanine A via cascade cyclization to construct the spiro-N,O-acetal moiety.

Org. Biomol. Chem. 2021, [DOI:10.1039/d0ob02399j]


58. Design, synthesis and antitumor activity evaluation of Chrysamide B derivatives.

Bioorganic Chemistry. 2021, [DOI:10.1016/j.bioorg.2021.104828]

57. Novel oxovanadium complex VO(hntdtsc)(NPIP): anticancer activity and mechanism of action on HeLa cells.

Front. Pharmacol. 2021, [DOI:10.3389/fphar.2020.608218]

56. Copper-promoted cyanation of aryl iodides with N,N-dimethyl aminomalononitrile.

Tetrahedron Letters. 2021, [DOI:10.1016/j.tetlet.2020.152749]

55. Recent Advances in Copper Promoted Inert C(sp3)–H Functionalization.

ACS Catal. 2021, 11, 967–984. [DOI:10.1021/acscatal.0c04618]

54. Pd(II)-Catalyzed Annulation Reactions of Epoxides with Benzamides to Synthesize Isoquinolones.

Org. Lett. 2021, [DOI:10.1021/acs.orglett.0c04097]

53. A gas chromatography flame ionization detector method for rapid simultaneous separation and determination of six active ingredients of anticold drug.

Current Pharmaceutical Analysis. 2021, [DOI:10.2174/1573412917666210106115211]

52. Application of palladium-catalyzed aryl C–H alkylation in total synthesis of (−)-berkelic acid.

Org. Chem. Front. 2021, 8, 82. [DOI:10.1039/D0QO01003K]

Publication List 2020

51. Frontispiece: Recent Advances in Iodine‐Promoted C−S/N−S Bonds Formation.

Chemistry – A European Journal. 2020, 26, 17289. [DOI:10.1002/chem.202087261]

50. Novel Carborane Compounds Based on Cyclooxygenase‐2 Inhibitors for Effective Boron Neutron Capture Therapy of Tongue Squamous Cell Carcinoma.

ChemistrySelect. 2020, 5, 14652. [DOI:10.1002/slct.202004077]

49. Thiopyranones and Thiopyranthiones.

Science of Synthesis. 2020/3. [DOI:10.1055/sos-SD-114-00270]

48. Melatonin Derivatives Combat with Inflammation-related Cancer by Targeting the Main Culprit STAT3.

European Journal of Medicinal Chemistry. 2020, 113027. [DOI:10.1016/j.ejmech.2020.113027]

47. Application of palladium-catalyzed aryl C–H alkylation in total synthesis of (−)-berkelic acid.

Org. Chem. Front. 2020,  [DOI:10.1039/d0qo01003k]

46. Novel pleuromutilin derivatives with substituted 6-methylpyrimidine: Design, synthesis and antibacterial evaluation.

European Journal of Medicinal Chemistry2020, 112735. [DOI:10.1016/j.ejmech.2020.112735]

45. Hydrogen sulfide donors: Therapeutic potential in anti-atherosclerosis.

European Journal of Medicinal Chemistry,  2020, 112665. [DOI:10.1016/j.ejmech.2020.112665]

        

44. C-N and C-O Bonds Formation in Copper-Catalyzed/Mediated sp3 C-H Activation: Mechanistic Studies from Experimental and Computational Aspects.

The Journal of Organic Chemistry,  2020, 85, 9713. [DOI:10.1021/acs.joc.0c01038]

43. The Regulator PltZ Regulates a Putative ABC Transporter System PltIJKNOP of Pseudomonas aeruginosa ATCC 27853 in Response to the Antimicrobial 2,4-Diacetylphloroglucinol.

Frontiers in Microbiology, 2020,  [DOI:10.1093/jaoacint/qsaa006]

    

42. A Green HPLC Method for Determination of Nine Sulfonamides in Milk and Beef, and Its Greenness Assessment with Analytical Eco-Scale and Greenness Profile.

Journal of AOAC INTERNATIONAL, 2020,  [DOI:10.1093/jaoacint/qsaa006]

41. Recent Advances in Iodine‐promoted C‐S/N‐S Bonds Formation.

Chemistry – A European Journal, 2020, 26, 17289. [DOI:10.1002/chem.202001414]

40. Design and synthesis of 1,3-benzothiazinone derivatives as potential anti-inflammatory agents.

Bioorganic & Medicinal Chemistry. 2020, 28, 115526. [DOI:10.1016/j.bmc.2020.115526]

39. Design, synthesis and bioactivity study of N-salicyloyl tryptamine derivatives as multifunctional agents for the treatment of neuroinflammation.

European Journal of Medicinal Chemistry. 2020, 193, 11217. [DOI:10.1016/j.ejmech.2020.112217]

38. Dechalcogenization of Aryl Dichalcogenides to Synthesize Aryl Chalcogenides via Copper Catalysis.

ACS Catalysis. 2020, 10, 2707-2712. [DOI:10.1021/acscatal.9b04931]

37. Synthesis and anti-hepaticfibrosis of glycyrrhetinic acid derivatives with inhibiting COX-2.

Bioorganic Chemistry. 2020, 99, 103804. [DOI:10.1016/j.bioorg.2020.103804]

Publication List 2019 (15)

36. Phthalimide-Carried Disulfur Transfer To Synthesize Unsymmetrical Disulfanes via Copper Catalysis.

ACS Catalysis. 2019, 9, 11426-11430. [DOI:10.1021/acscatal.9b04326]

35. Establishment and Development of a CZE-UV Method for Rapid Measurement of Aprotinin Potency.

ELECTROPHORESIS. 2019, 41168-174. [DOI:10.1002/elps.201900387]

34. Selection and breeding of a new variety of artemisia annua l.

中国中药杂志. 2019, 445363-5367.  [DOI:10.19540/j.cnki.cjcmm.20191009.107]

33. Synthesis, toxicity and antitumor activity of cobalt carbonyl complexes targeting hepatocellular carcinoma.

Bioorganic & Medicinal Chemistry. 2019, 27, 115071. [DOI:10.1016/j.bmc.2019.115071]

32. Asialoglycoprotein receptor targeted micelles containing carborane clusters for effective boron neutron capture therapy of hepatocellular carcinoma.

Colloids and Surfaces B: Biointerfaces. 2019, 182, 110397. [DOI: 10.1016/j.colsurfb.2019.110397]

31. Brønsted Base-Switched Selective Mono- and Di-thiolation of Benzamides via Copper Catalysis.

The Journal of Organic Chemistry. 2019, 84, 10490-10500. [DOI: 10.1021/acs.joc.9b01237]

30. Anti-atherosclerosis effect of H2S donors based on nicotinic acid and chlorfibrate structures.

Bioorganic & Medicinal Chemistry. 2019, 27, 3307–3318. [DOI: 10.1016/j.bmc.2019.06.012]

29. A Facile Approach to α-Keto Esters via Oxidative Esterification of α-Amino Carbonyl Compounds. 

Asian J. Org. Chem. 2019, 8, 1354–1357. [DOI: 10.1002/ajoc.201900320]

28. Toxicity, bioactivity, release of H2S in vivo and pharmaco-kinetics of H2S-donors with thiophosphamide structure.

European Journal of Medicinal Chemistry. 2019, 10, 742. [DOI: 10.1039/C8MD00611C]

27. Unexpected Stability of CO-Coordinated Palladacycle in Bidentate Auxiliary Directed C(sp3)-H Bond Activation: A Combined Experimental and Computational Study.

Organometallics. 2019, 38, 2022. [DOI: 10.1021/acs.organomet.9b00087]

26. Asymmetric Total Syntheses and Biological Studies of Tuberostemoamide and Sessilifoliamide A.

Org. Lett. 2019, 21, 2952. [DOI: 10.1021/acs.orglett.9b01042]

25. TBHP Promoted Demethylation of α-Amino Carbonyl Compounds: a Concise Approach to Substituted γ-Lactams.

Org. Chem. Front. 20196, 1837-1841. [DOI: 10.1039/C9QO00103D]

24. Toxicities and beneficial protection of H2S donors based on nonsteroidal anti-inflammatory drugs.

Med. Chem. Commum. 2019, 10, 742. [DOI: 10.1039/C8MD00611C]

23. Synthesis of α-arylthioacetones using TEMPO as the C3 synthon via a reaction cascade of sequential oxidation, skeletal rearrangement and C–S bond formation.

Org. Biomol. Chem. 2019, 17, 2341. [DOI: 10.1039/C9OB00018F]

22. A concise synthesis and biological study of evodiamine and its analogues.

Chem. Commun. 2019, 55, 3085. [DOI: 10.1039/C9CC00434C]

Publication List 2018 (9)

21. Total synthesis and structure revision of chrysamide B. 

Organic Chemistry Frontiers. 2018, 5, 3402. [DOI: 10.1039/C8QO00949J]

20. Syntheses and anti-cancer activity of CO-releasing molecules with targeting galactose receptors.

Org. Biomol. Chem. 201816, 8115. [DOI: 10.1039/C8OB01921E]

19. Synthesis, toxicities and bio-activities of manganese complexes with CO and H2S dual donors.

European Journal of Medicinal Chemistry. 2018, 159, 339. [DOI: org/10.1016/j.ejmech.2018.10.004]

18. Synthesis and biological activities of carbonyl cobalt CORMs with selectively inhibiting cyclooxygenase-2.

Journal of Organometallic Chemistry. 2018, 8, 13. [DOI: 10.1016/j.jorganchem.2018.08.013]

17. One pot preparation of alpha-dithioacetal/alpha-diselenoacetal amides via a dual-C-S/C-Se bond formation and C-C bond cleavage cascade of 3-oxo-butanamides.

Organic Chemistry Frontiers. 2018, 5, 2317. [DOI: 10.1039/C8QO00435H]

16. NaI-Mediated Divergent Synthesis of Isatins and Isoindigoes: A New Protocol Enabled by Oxidation Relay Strategy.

Chem. Commun. 2018, 54, 8265. [DOI: 10.1039/c8cc04471f]

15. KI-catalyzed C–S bond formation via an oxidation relay strategy: efficient access to various α-thio-β-dicarbonyl compounds.

Org. Biomol. Chem. 2018, 16, 1641. [DOI: 10.1039/c8ob00080h]

14. Direct access to a-sulfenylated amides/esters via sequential oxidative sulfenylation and C–C bond cleavage of 3-oxobutyric amides/esters.

Chem. Commun. 2018, 54, 802. [DOI: 10.1039/c7cc09026a]

13. Synthesis, Crystal Structure, Antitumor Activities and Docking Study of 1-(2-(1H-Indol-3-yl)ethyl)-3-(2-methoxyphenyl)urea.

Chinese Journal of Structural Chemistry, 2018[DOI: DOI: 10.14102/J.CNKI.0254-5861.2011-1832]

Publication List 2017 (5)

12. Sodium Iodide (NaI)-Catalyzed Cross-Coupling for C-S Bond Formation via Oxidative Dehydrogenation: Cheap, Direct Access to Unsymmetrical Aryl Sulfides. 

Chem. Asian J. 2017, 12, 1–6. [DOI: 10.1002/asia.201701163]

11. Double 1,4-addition of (thio)salicylamides/ thiosalicylic acids with propiolate derivatives: a direct, general synthesis of diverse heterocyclic scaffolds.

Org. Biomol. Chem. 2017, 15, 8013-8017. [DOI: 10.1039/C7OB02101A]

10. Syntheses, toxicities and anti-inflammation of H2S-donors based on non-steroidal anti-inflammatory drugs.

European Journal of Medicinal Chemistry. 2017, 138, 51. [DOI: 10.1016/j.ejmech.2017.06.012]

9. Total Synthesis of (+)–Mintlactone and (-)–Isomintlactone via SmI2-Induced Radical Cyclization.

Synlett. 2017, 28, A-C. [DOI: 10.1055/s-0036-1588418]

8. Potassium Bromide Catalyzed N-S Bond Formation via Oxidative Dehydrogenation.

Tetrahedron Lett. 2017, 58, 2084. [DOI:10.1016/j.tetlet.2017.03.065]

Publication List 2016 or before (7)

7. Palladium-Catalyzed Oxirane-Opening Reaction with Arenes via C–H Bond Activation.

Wang, Z.; Kuninobu, Y.; Kanai, M. J. Am. Chem. Soc. 2015, 137, 6140. [DOI: 10.1021/ja302765m]

6. Copper-Mediated Direct C(sp3)–H and C(sp2)–H Acetoxylation.

Wang, Z.; Kuninobu, Y.; Kanai, M. Org. Lett. 2014, 16, 4790. [DOI: 10.1021/ol5022542]

5. Copper-Catalyzed Intramolecular C(sp3)-H and C(sp2)-H Amidation by Oxidative Cyclization.

Wang, Z.; Ni, J.; Kuninobu, Y.; Kanai, M. Angew. Chem. Int. Ed. 2014, 53, 3496. [DOI: 10.1002/anie.201311105]

4. Molybdenum-Mediated Desulfurization of Thiols and Disulfides.

Wang, Z.; Ni, J.; Kuninobu, Y.; Kanai, M. Synlett. 2014, 25, 1869. [DOI: 10.1055/s-0034-1378315]

3. Copper-Catalyzed Intramolecular N–S Bond Formation by Oxidative Dehydrogenative Cyclization.

Wang, Z.; Kuninobu, Y.; Kanai, M. J. Org. Chem. 2013, 78, 7337. [DOI: 10.1021/jo401056g]

2. Pd-catalyzed oxidative cross-coupling between two electron rich heteroarenes.

He, C. Y.; Wang, Z.; Wu, C. Z.; Qing, F. L.; Zhang, X. Chem. Sci. 2013, 4, 3508. [DOI: 10.1039/C3SC51278A]

1. Total Syntheses of Anominine and Tubingensin A. 

Bian, M.; Wang, Z.; Xiong, X.; Sun, Y.; Matera, C.; Nicolaou, K. C.; Li, A. [M.B. and Z.W. contributed equally] J. Am. Chem. Soc. 2012, 134, 8078. [DOI: 10.1021/ja302765m]