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成果及论文
    2025
  1. Haifen Luo Jingqi Lv, Peiye Wen, Shan Zhang, Wen Ma*, Zhen Yang*, Supramolecular polyrotaxane-based nano-theranostics enable cancer-cell stiffening for enhanced T-cell-mediated anticancer immunotherapy,  Nature Communications, 2025, 16, 2331. 
  2. Xiaolin Ma, Ke Han, Hong-Xing Li, Lulu Song, Yuan Lin, Liangxu Lin, Yang Liu, Yi Zhao*, Zhen Yang*, Wei Huang*. Stepwise MXene and MOF Conversion Assisted Ultrathin Dual-Carbon Protected V2O3 Nanosheets for Ultrafast and Durable Zn-Ion Storage. Energy & Environmental Science, 2025,18, 897-909.
  3. Xiaoming Hu#, Cheng Zhang#, Jingqi Lv, Rongtian Li, Achen Qin, Caijun Zhu, Fengwei Sun, Zejing Chen, Shenghan Teng, Hongxin Lin*, Zhen Yang*, Wei Huang*, Constructing Intramolecular Electric Fields in NIR-II-Emissive Photosensitizers to Regulate the Local Electron Density for Boosting Hypoxia-Tolerant Cancer Phototheranostics, CCS Chemistry, 2025, 7, 2643.  
  4. Ming Chen#, Yi Wang#, Yanting Gao#, Xinghuai Sun, Lingting Huang,* Yuan Lei,* Zhen Yang*, Electrostatically Engineered Polyoxometalate Contact Lenses for Integrated Shielding of UV Radiation and Ozone-induced Ocular Stress, Advanced Functional Materials, 2025, e15910.
  5. Fuhong Yang#, Jingqi Lv#, Xiaorong Gao#, Kangxin Zhang, Yang Wang, Lingting Huang,* Zhen Yang,* Wei Huang*, Hydrogel-powered Adversity Transformation: On-demand Ultrasonic Switching Strategy for Accelerating Diabetic Wound Healing,  ACS Nano, 2025, 19, 36813.
  6. Wen Ma#, Peiye Wen#, Zikang Chen,* M. Mustafa Cetin,* Zhuting Fang,* Zhen Yang*, Advances in Nanotechnology-Driven Enhancement of Type I Photosensitizers for Tumor Photo-Immunotherapy, Small, 2025, 21, e10047.
  7. Xiaoming Hu*#, Jinshuo Mi# , Achen Qin, Caijun Zhu , Zejing Chen*, Zhen Yang*, Wei Huang*, Retrofitting NIR-II absorbing organic semiconducting fluorophores for reinvigorating deep-tissue fluorescence bioimaging, Coordination Chemistry Reviews, 2025, 545, 216992.
  8. Wei Wang‡, Fengwei Sun‡, Fuhong Yang‡, Chen Cui, Bo Wang, Yanli Huang*, Xianzeng Zhang*, Zhen Yang*, Synergistic Supramolecular Conductive Dressing Integrating Electrical Stimulation and Polyoxometalate Antioxidants for Enhanced Chronic Wound Healing, Acta Biomaterialia, 2025, 204, 340.
  9. Jinfeng Lin#, Jianlin Peng#, Xiangyu Huang, Qifa Lin, Peng Li*, Xiao Wu, Zhen Yang*, Tailoring the microstructure of lead-free KNN piezoelectric ceramics for force-sensitive smart windows, Microstructures, 2025, 5, 2025058.
  10. Jie Zhang#, Haifen Luo#, Wen Ma, Jingqi Lv, Bo Wang, Fengwei Sun, Weijie Chi,* Zhuting Fang,* Zhen Yang*, Semiconducting Open-shell Radicals for Precise Tumor Activatable Phototheranostics,  Advanced Science, 2025, 12, 2500293.
  11. Kangxin Zhang#, Bo Wang#, Fengwei Sun and Zhen Yang*, Semiconducting Perylene Diimide J-aggregates Cross-linked Hydrogel Enables High-efficiency Photothermal Controlled Release of Nitric oxide for Antibiofilm Therapy, Advanced Healthcare Materials, 2025, e2404754.
  12. Zikang Chen, Yongjie Zhou, Li Li, Wen Ma,* Yuzhen Li,* Zhen Yang*, Activatable Molecular Probes with Clinical Promise for NIR-II Fluorescent Imaging, Small, 2025, 21, 2411787.
  13. Yanling Yang, Xiaoming Hu*, Zhen Yang*, Wei Huang*, Insights into Molecular Lanthanide Complexes: Construction, Properties and Bioimaging and Biosensing Applications, Advanced Functional Materials, 2025, 2412970. 
  14. Lingting Huang, Yuyang Zhou, Xiaoming Hu,* Zhen Yang*, Emerging Combination of Hydrogel and Electrochemical Biosensors, Small, 2025, 2409711.
  15. Fuhong Yang#, Jingqi Lv#, Yanli Huang, Wen Ma*, Zhen Yang,* A supramolecular assembly strategy for the treatment of rheumatoid arthritis with ultrasound-augmented inflammatory microenvironment reprograming, Biomaterials, 2025, 123006.
    16. 2011-2024 
  16. Ling Li#, Jue Yin#, Wen Ma#, Longguang Tang#, Jianhua Zou, Linzi Yang, Ting Du, Yi Zhao, Lianhui Wang, Zhen Yang*, Chunhai Fan, Jie Chao*, Xiaoyuan Chen*, A DNA Origami Device Spatially Controls CD95 Signalling to Induce Immune Tolerance in Rheumatoid Arthritis, Nature Materials, 2024, 23, 993–1001
  17. Ling Li; Jianhua Zou; Yunlu Dai; Wenpei Fan*; Gang Niu; Zhen Yang*; Xiaoyuan Chen*; Burst Release of Encapsulated Annexin A5 in Tumours Boosts Cytotoxic T-cell Responses by Blocking the Phagocytosis of Apoptotic Cells, Nature Biomedical Engineering, 2020, 4, 1102-1116.
  18. Xiaoming Hu#, Zhuting Fang#, Fengwei Sun, Caijun Zhu, Mingxuan Jia, Xiaofei Miao, Lingting Huang, Wenbo Hu,* Quli Fan,*  Zhen Yang,* Wei Huang,* Deciphering Oxygen-Independent Augmented Photodynamic Oncotherapy by Facilitating the Separation of Electron-Hole Pairs, Angewandte Chemie International Edition, 2024, 63, e202401036
  19. Xiaoming Hu, Caijun Zhu, Fengwei Sun, Zejing Chen, Jianhua Zou*, Xiaoyuan Chen*, Zhen Yang*. J-Aggregation Strategy Toward Potentiated NIR-II Fluorescence Bioimaging of Molecular Fluorophores, Advanced Materials, 2024, 2304848.
  20. Wen Ma#, Haifen Luo#, Jingqi Lv, Peiye Wen, Gang Liu, Zhiqiang Yu*, Zhen Yang*, Wei Huang*, Immunoregulatory Engineering of Semiconducting Charge-reversal Nanoantioxidant for Ameliorating Cancer Radioimmunotheranostics, Advanced Materials, 2024, 2402929. 
  21. Zhixiong Wang#, Wen Ma#, Zhen Yang*, Dale O. Kiesewetter, Yicong Wu, Lixin Lang, Guofeng Zhang, Sofia Nakuchima, Jiji Chen, Yijun Su, Sue Han, Ling-gang Wu, Albert J. Jin,* Wei Huang,* A Type I Photosensitizer-Polymersome Boosts Reactive Oxygen Species Generation by Forcing H-Aggregation for Amplifying STING Immunotherapy, Journal of the American Chemical Society, 2024, 146, 42, 28973–28984.
  22. Wei Tang; Zhen Yang*; Liangcan He; Liming Deng; Parinaz Fathi; Shoujun Zhu; Ling Li; Bo Shen; Zhantong Wang; Orit Jacobson; Jibin Song; Jianhua Zou; Ping Hu; Min Wang; Jing Mu; Yaya Cheng; Yuanyuan Ma; Longguang Tang; Wenpei Fan*; Xiaoyuan Chen*; A Hybrid Semiconducting Organosilica-based O2 Nanoeconomizer for On-demand Synergistic Photothermally Boosted Radiotherapy, Nature Communications, 2021, 12, 523.
  23. Jianhua Zou; Ling Li; Jianwei Zhu;* Xiangchun Li; Zhen Yang*; Wei Huang; Xiaoyuan Chen*; Singlet oxygen “afterglow” therapy with a single NIR-II fluorescent molecule, Advanced Materials, 2021, 33, 2103627.
  24. Jianhua Zou; Jianwei Zhu; Zhen Yang*; Ling Li; Wenpei Fan; Liangcan He; Wei Tang; Liming Deng; Jing Mu; Yuanyuan Ma; Yaya Cheng; Wei Huang; Xiaochen Dong*; Xiaoyuan Chen*; A Phototheranostic Strategy to Continuously Deliver Singlet Oxygen in the Dark and Hypoxic Tumor Microenvironment, Angewandte Chemie International Edition, 2020, 132, 8918-8923.
  25. Zhen Yang; Xiaoyuan Chen*; Semiconducting Perylene Diimide Nanostructure: Multifunctional Phototheranostic Nanoplatform, Accounts of Chemical Research, 2019, 52, 1245-1254.
  26. Zhen Yang#; Wenpei Fan#; Jianhua Zou; Wei Tang; Ling Li; Liangcan He; Zheyu Shen; Zhantong Wang; Orit Jacobson; Maria A Aronova; Pengfei Rong*; Jibin Song; Wei Wang*; Xiaoyuan Chen*; Precision Cancer Theranostic Platform by In Situ Polymerization in Perylene Diimide-Hybridized Hollow Mesoporous Organosilica Nanoparticles, Journal of the American Chemical Society, 2019, 141, 14687-14698.
  27. Zhen Yang#; Yunlu Dai#; Chao Yin; Quli Fan*; Wansu Zhang; Justin Song; Guocan Yu; Wei Tang; Wenpei Fan; Bryant C Yung; Jie Li; Xiang Li; Xiangchun Li; Yufu Tang; Wei Huang; Jibin Song*; Xiaoyuan Chen*; Activatable Semiconducting Theranostics: Simultaneous Generation and Ratiometric Photoacoustic Imaging of Reactive Oxygen Species In Vivo, Advanced Materials, 2018, 30, 1707509.
  28. Ling Li#; Zhen Yang#; Shoujun Zhu; Liangcan He; Wenpei Fan; Wei Tang; Jianhua Zou; Zheyu Shen; Mingru Zhang; Longguang Tang; Yunlu Dai; Gang Niu; Shuo Hu*; Xiaoyuan Chen*; A Rationally Designed Semiconducting Polymer Brush for NIR-II Imaging-Guided Light-Triggered Remote Control of CRISPR/Cas9 Genome Editing, Advanced Materials, 2019, 31, 1901187.
  29. Zhen Yang#; Wenpei Fan#; Wei Tang#; Zheyu Shen; Yunlu Dai; Jibin Song; Zhantong Wang; Yuan Liu; Lisen Lin; Lingling Shan; Yijing Liu; Orit Jacobson; Pengfei Rong; Wei Wang*; Xiaoyuan Chen*; Near-Infrared Semiconducting Polymer Brush and pH/GSH-Responsive Polyoxometalate Cluster Hybrid Platform for Enhanced Tumor-Specific Phototheranostics, Angewandte Chemie International Edition, 2018, 57, 14101-14105.
  30. Guocan Yu#; Zhen Yang#; Xiao Fu#; Bryant C. Yung; Jie Yang; Zhengwei Mao*; Li Shao; Bin Hua; Yijing Liu; Fuwu Zhang; Quli Fan*; Sheng Wang; Orit Jacobson; Albert Jin; Changyou Gao; Xiaoying Tang; Feihe Huang*; Xiaoyuan Chen*; Polyrotaxane-based Supramolecular Theranostics, Nature Communications, 2018, 9, 760-766.
  31. Yunlu Dai#; Zhen Yang#; Siyuan Cheng; Zhongliang Wang; Ruili Zhang; Guizhi Zhu; Zhantong Wang*; Bryant C Yung; Rui Tian; Orit Jacobson; Can Xu; Qianqian Ni; Jibin Song; Xiaolian Sun; Gang Niu; Xiaoyuan Chen*; Toxic Reactive Oxygen Species Enhanced Synergistic Combination Therapy by SelfAssembled Metal-Phenolic Network Nanoparticles, Advanced Materials, 2018, 30, 1704877.
  32. Wei Wang#, Hongxin Lin#, Yanli Huang*, Xianzeng Zhang*, Zhen Yang*, Wei Huang*, Intelligent conductive gels for advanced flexible electronics, Chemical Engineering Journal, 2024, 156871. 
  33. Xiaoming Hu, Caijun Zhu, Achen Qin, Zejing Chen, Zhen Yang,* and Wei Huang*, Unravelling the Labyrinth of Organic SemiconductingChromophores for Fluorescence Bioimaging beyond 1500 nm, Chemistry of Materials,  2024, 36, 20, 10088–10103.
  34. Lingting Huang, Zhengjie Chen, Zhen Yang*, and Wei Huang*, Advancing Healthcare Accessibility: Fusing Artificial Intelligence with Flexible Sensing to Forge Digital Health Innovations, BME frontiers, 2024, 5, 0062.
  35. Fuhong Yang, Jingqi Lv, Wen Ma, Yanling Yang,* Xiaoming Hu,* and Zhen Yang*, Engineering Sonosensitizer-Derived Nanotheranostics forAugmented Sonodynamic Therapy, Small, 2024, 2402669.
  36. Yanling Yang, Fengyue Wang, Shan Zhang, Hongxin Zhang, Zhen Yang*, NIR-IIb-Emitted Er-Coordination Polymer for Logic Gates and Optical Anti-counterfeiting, Nano Biomedicine and Engineering, 2024, 9290107.
  37. Lingting Huang, Dianping Tang,* Zhen Yang,* Flexible Electronic Materials and Devices toward Portable immunoassays, FlexMat, 2024, 1, 59-78.
  38. Zhen Yang, Wei Huang,* Engineered pyroelectric and photodynamic nanocomposites for NIR photo-induced tumor cell apoptosis, SCIENTIA SINICA Chimica, 2024, 0233.
  39. Caijun Zhu, Mingdian Yu, Jingqi Lv, Fengwei Sun, Achen Qin, Zejing Chen, Xiaoming Hu,* Zhen Yang,* Zhuting Fang,* De novo strategy of organic semiconducting polymer brushes for NIR-II light-triggered carbon monoxide release to boost deep-tissue cancer phototheranostics, Journal of Nanobiotechnology, 2024, 22, 708. 
  40. Xiaoming Hu, Zhuting Fang, Caijun Zhu, Yanling Yang*, Zhen Yang*, Wei Huang*, Crucial Breakthrough of BODIPY-Based NIR-II Fluorescent Emitters for Advanced Biomedical Theranostics, Advanced Functional Materials, 2024, 2401325. 
  41. Gang Gei#, Yizhou Zhangi#, Xiao Xiao, Yanting Gong, Chang Liu, Chenyi Lyu, Wei Li Ong, Ghim Wei Ho,* Zhen Yang,* Wei Huang*, Rapidly Gelling, Highly Adhesive, and Mechanically Robust Ionogels for Stretchable and Wireless Electronics, Advanced Functional Materials, 2024, 17906423.
  42. Jie Zhang#, Wen Ma#, Haifen Luo#, Kangxin Zhang, Jingqi Lv, Lizhi Jiang*, Yanli Huang, Jibing Song*, Zhen Yang*, Wei Huang*. Toward Type I / II ROS Generation Photoimmunotherapy by Molecular Engineering of Semiconducting Perylene Diimide, Advanced Healthcare Materials, 2024, 2303175.  
  43. Haifen Luo#, Wen Ma#, Qi Chen*, Zhen Yang*, Yunlu Dai*, Radiotherapy-activated tumor immune microenvironment: Realizing radiotherapy-immunity combination therapy strategies, Nano Today, 2023, 53, 102042. 
  44. Huang, Lingting, Yuqing Ren, Zhen Yang*, Ruijin Zeng*, and Dianping Tang*. Ultrasensitive electrochemical detection of uric acid based on cobalt-embedded nitrogen-doped carbon. New Journal of Chemistry, 2023, doi.org/10.1039/D3NJ02805D
  45. Zhixiong Wang, Albert Jin*, Zhen Yang*, Wei Huang*; Advanced Nitric Oxide Generating Nanomedicine for Therapeutic Applications, ACS Nano, 2023, 17, 8935-8965.
  46. Cheng Zhang#, Xiaoming Hu#, Long Jin, Lisheng Lin, Hongxin Lin*, Zhen Yang*, Wei Huang*; Strategic Design of Conquering Hypoxia in Tumor for Advanced Photodynamic Therapy, Advanced Healthcare Materials, 2023, 2300530.
  47.  Xiaoming Hu; Fengwei Sun; Caijun Zhu; Zhen Yang*; Wei Huang*; Repurposing organic semiconducting nanomaterials to accelerate clinical translation of NIR-II fluorescence imaging, Nano Research, 2023, 4, 5140-5154.
  48. Cuibing Bai#; Jie Zhang#; Wen Ma; Junxiong Yao; Qian Meng; Zhenni Xia; Dashuo Chen; Shuping He; Lin Zhang; Changqing Qu; Rui Qiao*; Zhen Yang*; Wei Huang*; A new intramolecular proton transfer (ESIPT)‐based fluorescent probe for selective visualization of cyanide ion, VIEW, 2023. 20220068
  49. B Wang; X Hu*; F Sun; Z Yang*; W Huang*; Advanced strategic constructions of diketopyrrolopyrrole derivatives-based organic semiconducting phototheranostics, Interdisciplinary Medicine, 2023, e20220010.
  50. Cao Cui; Chenlu Wang; Qinrui Fu; Jibin Song; Jianhua Zou; Ling Li; Jianwei Zhu;* Wei Huang; Lin Li;* Zhen Yang;* and Xiaoyuan Chen*; A Generic Self-Assembly Approach Towards Phototheranostics for NIR-II Fluorescence Imaging and Phototherapy, Acta Biomaterialia, 2022, 140, 1, 601-609.
  51. X Hu#; C Zhu#; F Sun; J Yang; Z Chen; H Ao; C Cui; Z Yang*; W Huang*; Insights into the organic semiconducting   photosensitizers for hypoxia-tolerant type I photodynamic therapy, Nano TransMed, 2022, 9130010.
  52. Xiaoming Hu; Caijun Zhu; Fengwei Sun; Jin Yang; Zejing Chen; Haiyong Ao; Cao Cui; Zhen Yang*; Wei Huang* “Rational Molecular Engineering of Organic Semiconducting Nanoplatforms for Advancing NIR-II Fluorescence Theranostics”; Advanced Optical Materials, 2022, 10, 2201067.
  53. Jianhua Zou; Ling Li; Zhen Yang*; Xiaoyuan Chen*; Phototherapy meets immunotherapy: a win–win strategy to fight against cancer, Nanophotonics, 2021, 10, 3229.
  54. Wenpei Fan; Maomao Song; Liping Li; Liangliang Niu; Yue Chen; Binze Han; Xinghuai Sun*; Zhen Yang*; Yuan Lei*; Xiaoyuan Chen*; Endogenous dual stimuli-activated NO generation in the conventional outflow pathway for precision glaucomatherapy, Biomaterials, 2021, 277, 121074.
  55. Xiaoming Hu#; Zejing Chen#; Albert J. Jin; Zhen Yang*; Deqiang Gan; Aifang Wu; Haiyong Ao; Wei Huang; Quli Fan*; Rational Design of All‐Organic Nanoplatform for Highly Efficient MR/NIR‐II Imaging‐Guided Cancer Phototheranostics, Small, 2021, 17, 2007566.
  56. Zhen Yang#; Rui Tian#; Jinjun Wu; Quli Fan*; Bryant C Yung; Gang Niu*; Orit Jacobson; Zhantong Wang; Gang Liu; Guocan Yu; Wei Huang; Jibin Song*; Xiaoyuan Chen*; Impact of Semiconducting Perylene Diimide Nanoparticle Size on Lymph Node Mapping and Cancer Imaging, ACS Nano, 2017, 11, 4247-4255.
  57. Zhen Yang; Ling Li*; Albert J. Jin*; Wei Huang; Xiaoyuan Chen*; Ration al Design of Semiconducting Polymer Brushes as Cancer Theranostics, Materials Horizons, 2020, 7, 1474-1494.
  58. Ling Li#; Zhen Yang#; Wenpei Fan; Liangcan He; Cao Cui; Jianhua Zou; Wei Tang; Orit Jacobson; Zhantong Wang; Gang Niu; Shuo Hu*; Xiaoyuan Chen*; In Situ Polymerized Hollow Mesoporous Organosilica Biocatalysis Nanoreactor for Enhancing ROS-Mediated Anticancer Therapy, Advanced Functional Materials, 2020, 30, 1907716.
  59. Zhen Yang#; Jibin Song#; Wei Tang#; Wenpei Fan; Yunlu Dai; Zheyu Shen; Lisen Lin; Siyuan Cheng; Yijing Liu; Gang Niu; Pengfei Rong; Wei Wang*; Xiaoyuan Chen*; Stimuli-Responsive Nanotheranostics for Real-Time Monitoring Drug Release by Photoacoustic Imaging, Theranostics, 2019, 9, 526-536.
  60. Zhen Yang; Yunlu Dai*; Lingling Shan; Zheyu Shen; Zhantong Wang; Bryant C. Yung; Orit Jacobson; Yijing Liu; Wei Tang; Sheng Wang; Lisen Lin; Gang Niu; Pintong Huang*; Xiaoyuan Chen*; Tumour Microenvironment-responsive Semiconducting Polymer-based Self-assembling Nanotheranostics, Nanoscale Horizons, 2019, 4, 426-433.
  61. Wei Tang; Zhen Yang*; Sheng Wang; Zhantong Wang; Jibin Song; Guocan Yu; Wenpei Fan; Yunlu Dai; Jingjing Wang; Lingling Shan; Gang Niu; Quli Fan*; Xiaoyuan Chen*; Organic Semiconducting Photoacoustic Nanodroplets for LaserActivatable Ultrasound Imaging and Combinational Cancer Therapy, ACS Nano, 2018, 12, 2610-2622.
  62. Cao Cui#; Zhen Yang#; Xiang Hu; Jinjun Wu; Kangquan Shou; Hengheng Ma; Chao Jian; Yong Zhao; Baiwen Qi; Xiaoming Hu; Aixi Yu*; Quli Fan*; Organic Semiconducting Nanoparticles as Efficient Photoacoustic Agents for Lightening Early Thrombus and Monitoring Thrombolysis in Living Mice, ACS Nano, 2017, 11, 3298-3310.
  63. Zhen Yang; Jibin Song*; Yunlu Dai; Jingyi Chen; Feng Wang; Lisen Lin; Yijing Liu; Fuwu Zhang; Guocan Yu; Zijian Zhou; Wenpei Fan; Wei Huang; Quli Fan*; Xiaoyuan Chen*; Self-Assembly of Semiconducting-Plasmonic Gold Nanoparticles with Enhanced Optical Property for Photoacoustic Imaging and Photothermal Therapy, Theranostics, 2017, 7, 2177-2185.
  64. Zhen Yang; Yan Yuan; Rongcui Jiang; Nina Fu; Xiaomei Lu; Congcong Tian; Wenbo Hu; Quli Fan*; Wei Huang*; Homogeneous Near-infrared Emissive Polymeric Nanoparticles Based on Amphiphilic Diblock Copolymers with Perylene Diimide and PEG Pendants: Self-assembly Behavior and Cellular Imaging Application, Polymer Chemistry, 2014, 5, 1372-1380.
  65. Zhen Yang; Haijian Yang*; Jia Tian; Cunyue Guo*; Hakwon Kim; High Solubility and Partial Molar Volume of 2,2 '-Oxybis(N,N-bis(2-methoxyethyl) acetamide) in Supercritical Carbon Dioxide, Journal of Chemical and Engineering Data, 2011, 56, 1191-1196.