Dynamic boroxine linkers were incorporated into the mesoporous metal–organic framework (MOF) PCN-333, which creates defects and expands pore sizes, enabling the encapsulation of enzymes larger than the intrinsic MOF pores. As reported by Xing Zhang, Shuai Yuan et al in their Research Article (e202409951), this strategy facilitates the immobilization of glycoenzymes for synthesizing complex oligosaccharides and polysaccharides, demonstrating both high activity and enhanced enzyme stability. [Angew. Chem. Int. Ed. 2024, 63, e202409951] [Download Cover]

We report a dynamic bond-directed strategy to synthesize single crystals of stable mesoporous MOFs under room temperature without using acid modulators. The mild synthesis allows the in situ encapsulation of labile guests. [J. Am. Chem. Soc. 2023, 145, 10227-10235] [Download Cover]

The electronic structure and oxygen reduction activity of Fe sites in heterogenous Fe-phthalocyanine-based catalysts have been tuned by the terminal ligands with electron-withdrawing and donating functional groups. [ACS Catal. 2022, 12, 7278-7287] [Download Cover]

The formation of Zr-MOFs was regulated by thermodynamics using auxiliary linkers. This method not only affords pure phase under a wide range of synthetic conditions, but also offers an additional opportunity to functionalize Zr-MOFs by modification of the auxiliary linkers. A cooperative catalytic system was assembled in a Zr-MOF platform. [ACS Appl. Mater. Interfaces 2019, 11, 22390–22397] [Download Cover]

We report a stable and highly accessible 2D-metal–organic framework (MOF) catalyst for artemisinin production. By introducing porphyrin-based carboxylate ligands on the coordinatively unsaturated Zr sites in the MOF, the functionalized MOF nanosheet allows for enhanced accessibility of the catalytic sites, fast catalytic reaction kinetics and enhanced recyclability. [Adv. Sci. 2019, 6, 1802059] [Download Cover]

With the ever-expanding application scope of metal–organic frameworks (MOFs), the framework stability has become a major concern. In this article, Hong-Cai Zhou and co-workers focus on recent advances in the field of stable MOFs, covering the fundamental mechanisms, the design and synthesis of stable MOFs, and their latest applications. [Adv. Mater. 2018, 30, 1704303] [Download Cover]

Switchable catalysts in flexible MOFs are possible through the inherent cavities and dynamic behaviors of flexible metal–organic frameworks (MOFs), namely the PCN-700 series, properties that bear a close resemblance to those of regulatory enzymes. In their Communication on page 10776 ff., W. Lu, M. B. Hall, H.-C. Zhou, and co-workers show that manual control of the catalytic properties of these MOFs is possible through reversible pore opening and closing. [Angew. Chem. Int. Ed. 2016, 55, 10776-10780] [Download Cover]

Spontaneous chiral resolution of a 3D (3,12)-connected MOF with unprecedented ttt topology consisting of cubic [Cd4(µ-OH)4] cluster and propellerlike ligand. [CrystEngComm 2014, 16, 3829-3833] [Download Cover]