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成果及论文

近期研究进展

Niu Niu, Huipeng Zhou,  Na Yang, Dong Wang * and Cong Yu *. Benzoperylene-grafted and Cu2+ chelated polymeric nanoparticles for GSH depletion and chemodynamic therapy. Mater. Chem. Front., 2021, 5, 2442.


Ning Liu, Ming Zhu, Niu Niu, Jia Ren, Na Yang*, Cong Yu *. Aza-BODIPY Probe-Decorated Mesoporous Black TiO2 Nanoplatform for the Highly Efficient Synergistic Phototherapy. ACS Appl. Mater. Interfaces, 2020, 12, 41071−41078.

Na Yang, Ming Zhu, Guochao Xu, Ning Liu *, Cong Yu *. A near-infrared light-responsive multifunctional nanocomposite hydrogel for efficient and synergistic antibacterial wound therapy and healing promotion. J. Mater. Chem. B., 2020, 8, 3908.

Niu Niu, Huipeng Zhou, Ning Liu, Hong Jiang, Zhenzhen Hu, Cong Yu *. A perylene-based membrane intercalating conjugated oligoelectrolyte with efficient photodynamic antimicrobial activity. Chem. Commun., 2019, 55, 4395-4398.

Niu Niu, Huipeng Zhou, Ning Liu, Hong Jiang, Ejaz Hussian, Zhenzhen Hu, Cong Yu *. A smart perylene derived photosensitizer for lysosome-targeted and self-assessed photodynamic therapy. Chem. Commun., 2019, 55, 1036-1039.

Xinan Huang, Huipeng Zhou,Yumeng Huang, Hong Jiang, Na Yang, Sohail Anjum Shahzad, Lianjie Meng, Cong Yu*. Silver nanoparticles decorated and tetraphenylethene probe doped silica nanoparticles: A colorimetric and fluorometric sensor for sensitive and selective detection and intracellular imaging of hydrogen peroxide. Biosensors and Bioelectronics, 2018, 121, 236–242.


Yunyi Zhang, Yongxin Li, Na Yang, Xue Yu, Chunhua He, Niu Niu, Cuiyun Zhang, Huipeng Zhou∗, Cong Yu∗, Shichun Jiang∗. Histone controlled aggregation of tetraphenylethene probe: A new method for the detection of protease activity. SENSOR ACTUAT B-CHEM., 257 (2018) 1143–1149.

Jian Chen, Hong Jiang,Huipeng Zhou, Zhenzhen Hu, Niu Niu, Sohail Anjum Shahzad, Cong Yu*. Specific detection of cancer cells through aggregation-induced emission of a light-up bioprobe. Chem.Commun., 2017, 53, 2398-2401.


部分课题组工作

1. Yang, N.;  Song, S.;  Ren, J.;  Liu, C.;  Li, Z.;  Qi, H.; Yu, C., Controlled Aggregation of a Perylene-Derived Probe for Near-Infrared Fluorescence Imaging and Phototherapy. ACS Applied Bio Materials 2021, 4 (6), 5008-5015.

2. Zhang, L.;  Hou, J. Z.;  Zhou, H. P.;  Nawaz, M. A. H.;  Li, Y. X.;  Huang, H.; Yu, C., Identification of milk adulteration by a sensor array based on cationic polymer induced aggregation of a perylene probe. Food Chemistry 2021, 343.

3. Li, Y. X.;  Hou, J. Z.;  Zhou, H. P.;  Jia, M. Q.;  Chen, S. S.;  Huang, H.;  Zhang, L.; Yu, C., A fluorescence sensor array based on perylene probe monomer-excimer emission transition for the highly efficient differential sensing of metal ions and drinking waters. Sens. Actuator B-Chem. 2020, 319.

4. Niu, N.;  Zhou, H. P.;  Liu, N.;  Ren, J.;  Li, W. Q.; Yu, C., A benzoperylene self-assembly complex with turn-on excimer emission for wash-free cell membrane fluorescence imaging. Chemical Communications 2019, 55 (96), 14446-14449.

5. Hussain, E.;  Cheng, C.;  Li, Y. X.;  Niu, N.;  Zhou, H. P.;  Jin, X.;  Kong, J. F.; Yu, C., Benzo ghi perylene & coronene as ratiometric reversible optical oxygen nano-sensors. Sens. Actuator B-Chem. 2019, 287, 27-34.

6. Zhang, C. Y.;  Fan, Y.;  Zhang, Y. Y.;  Yu, C.;  Li, H.;  Chen, Y.;  Hamley, I. W.; Jiang, S. C., Self-Assembly Kinetics of Amphiphilic Dendritic Copolymers. Macromolecules 2017, 50 (4), 1657-1665.

7.Zhang, Y. Y.;  Zhang, C. Y.;  Chen, J.;  Li, Y. X.;  Yang, M. D.;  Zhou, H. P.;  Shahzad, S. A.;  Qi, H.;  Yu, C.; Jiang, S. C., A real-time fluorescence turn-on assay for acetylcholinesterase activity based on the controlled release of a perylene probe from MnO2 nanosheets. Journal of Materials Chemistry C 2017, 5 (19), 4691-4694.

8. Huang, X. N.;  Jiang, H.;  Li, Y. X.;  Sang, L. J.;  Zhou, H. P.;  Shahzad, S. A.;  Ibupoto, Z. H.; Yu, C., Synthesis of silica nanoparticles doped with Ru(bpy)(3) (2+) and decorated with silver nanoclusters for the ratiometric photoluminescent determination and intracellular imaging of Cu(II) ions. Microchim. Acta 2017, 184 (7), 2325-2331.

9. Yang, M. D.;  Zhou, H. P.;  Li, Y. X.;  Zhang, Q. F.;  Li, J. M.;  Zhang, C. Y.;  Zhou, C. B.; Yu, C., Peroxidase activity of the coronene bisimide supramolecular architecture and its applications in colorimetric sensing of H2O2 and glucose. J. Mat. Chem. B 2017, 5 (32), 6572-6578.

10. Li, Y. X.;  Zhou, H. P.;  Yin, S. H.;  Jiang, H.;  Niu, N.;  Huang, H.;  Shahzad, S. A.; Yu, C., A BOPHY probe for the fluorescence turn-on detection of Cu2+. Sens. Actuator B-Chem. 2016, 235, 33-38.

11. Zhang, C. Y.;  Yu, C.;  Lu, Y. Y.;  Li, H. F.;  Chen, Y.;  Huo, H.;  Hamley, I. W.; Jiang, S. C., Hydrodynamic behaviors of amphiphilic dendritic polymers with different degrees of amidation. Polymer Chemistry 2016, 7 (18), 3126-3133.

12. Li, Y. X.;  Zhou, H. P.;  Chen, J.;  Shahzad, S. A.; Yu, C., Controlled self-assembly of small molecule probes and the related applications in bioanalysis. Biosens. Bioelectron. 2016, 76, 38-53.

13. Yang, M. D.;  Chen, J.;  Zhou, H. P.;  Li, W. Y.;  Wang, Y.;  Li, J. M.;  Zhang, C. Y.;  Zhou, C. B.; Yu, C., Polycation-induced benzoperylene probe excimer formation and the ratiometric detection of heparin and heparinase. Biosens. Bioelectron. 2016, 75, 404-410.

14. Li, W. Y.;  Zhang, Q. F.;  Zhou, H. P.;  Chen, J.;  Li, Y. X.;  Zhang, C. Y.; Yu, C., Chemiluminescence Detection of a Protein through the Aptamer-Controlled Catalysis of a Porphyrin Probe. Anal. Chem. 2015, 87 (16), 8336-8341.

15. Li, J. M.;  Li, Y. X.;  Shahzad, S. A.;  Chen, J.;  Chen, Y.;  Wang, Y.;  Yang, M. D.; Yu, C., Fluorescence turn-on detection of glucose via the Ag nanoparticle mediated release of a perylene probe. Chemical Communications 2015, 51 (29), 6354-6356.

16. Li, Y. X.;  Li, W. Y.;  Zhou, H. P.;  Wang, F. Y.;  Chen, Y.;  Wang, Y.; Yu, C., A facile method for the sensing of antioxidants based on the redox transformation of polyaniline. Sens. Actuator B-Chem. 2015, 208, 30-35.

17. Li, W. Y.;  Yang, Y.;  Chen, J.;  Zhang, Q. F.;  Wang, Y.;  Wang, F. Y.; Yu, C., Detection of lead(II) ions with a DNAzyme and isothermal strand displacement signal amplification. Biosens. Bioelectron. 2014, 53, 245-249.

18. Wang, Y.;  Chen, J.;  Chen, Y.;  Li, W. Y.; Yu, C., Polymer-Induced Perylene Probe Excimer Formation and Selective Sensing of DNA Methyltransferase Activity through the Monomer-Excimer Transition. Anal. Chem. 2014, 86 (9), 4371-4378.

19. Chen, J.;  Wang, Y.;  Li, W. Y.;  Zhou, H. P.;  Li, Y. X.; Yu, C., Nucleic Acid-Induced Tetraphenylethene Probe Noncovalent Self-Assembly and the Superquenching of Aggregation-Induced Emission. Anal. Chem. 2014, 86 (19), 9866-9872.

20. Chen, Y.;  Li, W. Y.;  Wang, Y.;  Yang, X. D.;  Chen, J.;  Jiang, Y. N.;  Yu, C.; Lin, Q., Cysteine-directed fluorescent gold nanoclusters for the sensing of pyrophosphate and alkaline phosphatase. Journal of Materials Chemistry C 2014, 2 (20), 4080-4085.

21. Chen, Y.;  Zhou, H. P.;  Wang, Y.;  Li, W. Y.;  Chen, J.;  Lin, Q.; Yu, C., Substrate hydrolysis triggered formation of fluorescent gold nanoclusters - a new platform for the sensing of enzyme activity. Chemical Communications 2013, 49 (84), 9821-9823.

22. Liao, D. L.;  Chen, J.;  Li, W. Y.;  Zhang, Q. F.;  Wang, F. Y.;  Li, Y. X.; Yu, C., Fluorescence turn-on detection of a protein using cytochrome c as a quencher. Chemical Communications 2013, 49 (82), 9458-9460.

23.  Li, W. Y.;  Chen, J.;  Jiao, H. P.;  Zhang, Q. F.;  Zhou, H. P.; Yu, C., A label-free real time fluorometric assay for protease and inhibitor screening with a released heme. Chemical Communications 2012, 48 (81), 10123-10125.

24. Chen, J.;  Liao, D. L.;  Wang, Y.;  Zhou, H. P.;  Li, W. Y.; Yu, C., Real-Time Fluorometric Assay for Acetylcholinesterase Activity and Inhibitor Screening through the Pyrene Probe Monomer-Excimer Transition. Organic Letters 2013, 15 (9), 2132-2135.

25. Tang, D.;  Liao, D. L.;  Zhu, Q. K.;  Wang, F. Y.;  Jiao, H. P.;  Zhang, Y. J.; Yu, C., Fluorescence turn-on detection of a protein through the displaced single-stranded DNA binding protein binding to a molecular beacon. Chemical Communications 2011, 47 (19), 5485-5487.

26. Wang, B.;  Jiao, H. P.;  Li, W. Y.;  Liao, D. L.;  Wang, F. Y.; Yu, C., Superquencher formation via nucleic acid induced noncovalent perylene probe self-assembly. Chemical Communications 2011, 47 (37), 10269-10271.

27. Wang, B.;  Zhu, Q. K.;  Liao, D. L.; Yu, C., Perylene probe induced gold nanoparticle aggregation. Journal of Materials Chemistry 2011, 21 (13), 4821-4826.

28. Wang, B.; Yu, C., Fluorescence Turn-On Detection of a Protein through the Reduced Aggregation of a Perylene Probe. Angewandte Chemie-International Edition 2010, 49 (8), 1485-1488.

29. Zhang, R. X.;  Tang, D.;  Lu, P.;  Yang, X. Y.;  Liao, D. L.;  Zhang, Y. J.;  Zhang, M. J.;  Yu, C.; Yam, V. W. W., Nucleic Acid-Induced Aggregation and Pyrene Excimer Formation. Organic Letters 2009, 11 (19), 4302-4305.