30. Catalytic Oxidation of Carbon–Halogen Bonds by Water with H2 Liberation. J. Am. Chem. Soc. 2025, 147, 30490-30498. https://pubs.acs.org/doi/10.1021/jacs.5c11295
Cai You, Lijun Lu, David Milstein*
29. Long–Short-Arm Acridine Ru-Pincer Catalysts for Reversible Hydrogen Storage Based on Ethylene Glycol. J. Am. Chem. Soc. 2025, 147, 30060-30071. https://pubs.acs.org/doi/10.1021/jacs.5c07428
Cai You, Lijun Lu, Jie Luo, Yael Diskin-Posner, and David Milstein*
28. Catalytic Intramolecular Reductive Amination Using Secondary Amines: Expanding Access to Chiral Tertiary Amine Heterocycles. Org. Lett. 2025, 27, 6726-6731. https://pubs.acs.org/doi/full/10.1021/acs.orglett.5c01836
Longxue Xiang, Cai You*, Xiuxiu Li* and Xumu Zhang*
27. Asymmetric Hydrogenation of β‑Azaaryl α,β-Unsaturated Nitriles: An Access to Ruxolitinib. Org. Lett. 2025, 27, 5260-5263. https://pubs.acs.org/doi/full/10.1021/acs.orglett.5c01468
Ruiyu Hu, Fan Pan, Cai You, Xiaobing Ding,* Xiuxiu Li,* and Xumu Zhang*
26. Catalytic Regio- and Enantioselective Hydroformylation of Trisubstituted Alkenes to Construct α-Quaternary Lactams. J. Am. Chem. Soc. 2025, 147, 7886-7896. https://pubs.acs.org/doi/full/10.1021/jacs.4c18341
Dequan Zhang, Jianqiang Zheng, Cai You, Liuting Li, Lung Wa Chung, Qifan zhou, Shuailong Li, Tianxiang Ren, Yuhong Yang,* Xumu Zhang* and Xiuxiu Li*
Prior to GBU
25. Aqueous Dehydrogenation of Methyl Formate Catalyzed by a Recyclable Polymer-Grafted Manganese(I) Pincer Complex. Angew. Chem. Int. Ed. 2025, 64, e202423074. https://onlinelibrary.wiley.com/doi/10.1002/anie.202423074
Lijun Lu, Cai You, Michael Montag, Ayan Maity, Michal Leskes and David Milstein*
24. A hydrogenative oxidation strategy for the single-step synthesis of lactams from N-heteroarenes using water. Nat. Catal. 2025, 8, 98-106. https://www.nature.com/articles/s41929-024-01286-2
Yaoyu Liang, Jie Luo, Cai You, Yael Diskin-Posner and David Milstein*
23. Regio- and Stereoselective 1,2-Carboboration of Ynamides with Aryldichloroboranes. Angew. Chem. Int. Ed. 2021, 60, 21697-21701. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202107647
Cai You, Mika Sakai, Constantin G. Daniliuc, Klaus Bergander, Shigehiro Yamaguchi* and Armido Studer*
22. Three-component 1,2-carboamination of vinyl boronic esters via amidyl radical induced 1,2-migration. Chem. Sci. 2021, 12, 15765-15769. https://pubs.rsc.org/en/content/articlelanding/2021/sc/d1sc05811h
Cai You and Armido Studer*
21. Nickel-Catalyzed Asymmetric Hydrogenation of Cyclic Alkenyl Sulfones, Benzo[b]thiophene 1,1-Dioxides, with Mechanistic Studies. Org. Lett. 2021, 23, 668-675. https://pubs.acs.org/doi/full/10.1021/acs.orglett.0c03723
Gongyi Liu, Kui Tian, Chenzong Li, Cai You, Xuefeng Tan, Heng Zhang*, Xumu Zhang* and Xiu-Qin Dong*
20. Synthesis of 1,3-Bis-(boryl)alkanes through Boronic Ester Induced Consecutive Double 1,2-Migration. Angew. Chem. Int. Ed. 2020, 59, 17245-17249. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.202007541
Cai You and Armido Studer*
19. Asymmetric Linear-Selective Hydroformylation of 1,1-Dialkyl Olefins Assisted by a Steric-Auxiliary Strategy. Org. Lett. 2020, 22, 4523-4526. https://pubs.acs.org/doi/full/10.1021/acs.orglett.0c01550
Dequan Zhang, Cai You, Xiuxiu Li, Jialin Wen* and Xumu Zhang*
18. Rhodium-Catalyzed Enantioselective Anti-Markovnikov Hydroformylation of α-Substituted Acryl Acid Derivatives. Org. Lett. 2020, 22, 1108-1112. https://pubs.acs.org/doi/full/10.1021/acs.orglett.9b04624
Shuailong Li, Zhuangxing Li, Cai You, Xiuxiu Li, Jiaxin Yang, Hui Lv* and Xumu Zhang*
17. Rhodium-catalyzed asymmetric hydrogenation of exocyclic α,β-unsaturated carbonyl compounds. Org. Biomol. Chem. 2020, 18, 856-859. https://pubs.rsc.org/en/content/articlelanding/2020/ob/c9ob02536g
Jiaxin Yang, Xiuxiu Li, Cai You, Shuailong Li, Yu-Qing Guan, Hui Lv* and Xumu Zhang
16. Nickel-Catalyzed Desymmetric Hydrogenation of Cyclohexadienones: An Efficient Approach to All-Carbon Quaternary Stereocenters. J. Am. Chem. Soc. 2019, 141, 14560-14564. https://pubs.acs.org/doi/10.1021/jacs.9b07957
Cai You,+ Xiuxiu Li,+ Quan Gong, Jialin Wen* and Xumu Zhang* (+Co-first author)
15. Asymmetric Hydrocyanation of Alkenes without HCN. Angew. Chem. Int. Ed. 2019, 58, 10928-10931. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201906111
Xiuxiu Li,+ Cai You,+ Jiaxin Yang, Shuailong Li, Dequan Zhang, Hui Lv* and Xumu Zhang* (+Co-first author)
14. Enantioselective Rh-Catalyzed Anti-Markovnikov Hydroformylation of 1,1-Disubstituted Allylic Alcohols and Amines: An Efficient Route to Chiral Lactones and Lactams. ACS Catal. 2019, 9, 8529-8533. https://pubs.acs.org/doi/full/10.1021/acscatal.9b02667
Cai You,+ Shuailong Li,+ Xiuxiu Li, Hui Lv*, Xumu Zhang* (+Co-first author)
13. Recent Advances in Asymmetric Hydroformylation. Chin. J. Org. Chem. 2019, 39, 1568-1582. https://sioc-journal.cn/Jwk_yjhx/EN/10.6023/cjoc201903044
Shuailong Li, Zhuangxing Li, Cai You, Hui Lv* and Xumu Zhang
12. A cheap metal for a challenging task: nickel-catalyzed highly diastereo- and enantioselective hydrogenation of tetrasubstituted fluorinated enamides. Chem. Sci. 2019, 10, 252-256. https://pubs.rsc.org/en/content/articlelanding/2019/sc/c8sc04002h
Yu-Qing Guan, Zhengyu Han, Xiuxiu Li, Cai You, Xuefeng Tan, Hui Lv* and Xumu Zhang
11. Design and Application of Hybrid Phosphorus Ligands for Enantioselective Rh-Catalyzed Anti-Markovnikov Hydro-formylation of Unfunctionalized 1,1-Disubstituted Alkenes. J. Am. Chem. Soc. 2018, 140, 4977-4981. https://pubs.acs.org/doi/10.1021/jacs.8b00275
Cai You, Shuailong Li, Xiuxiu Li, Jialing Lan, Yuhong Yang, Lung Wa Chung, Hui Lv*, Xumu Zhang*
10. Silicon-oriented regio- and enantioselective rhodium-catalyzed hydroformylation. Nat. Commun. 2018, 9, 2045. https://www.nature.com/articles/s41467-018-04277-7
Cai You,+ Xiuxiu Li,+ Yuhong, Yang, Yusheng Yang, Xuefeng Tan, Shuailong Li, Biao Wei, Lung Wa Chung,* Hui Lv*, Xumu Zhang* (+Co-first author)
9. Rhodium-catalyzed asymmetric hydrogenation of β-cyanocinnamic esters with the assistance of a single hydrogen bond in a precise position. Chem. Sci. 2018, 9, 1919-1924. https://pubs.rsc.org/en/content/articlelanding/2018/sc/c7sc04639a
Xiuxiu Li,+ Cai You,+ Yusheng Yang, Yuhong Yang, Pan Li, Guoxian Gu, Lung-Wa Chung, Hui Lv*, Xumu Zhang* (+Co-first author)
8. Iridium-Catalyzed Asymmetric Hydrogenation of Halogenated Ketones for the Efficient Construction of Chiral Halohydrins. Adv. Synth. Catal. 2018, 360, 2119-2124.https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/adsc.201800267
Congcong Yin, Weilong Wu, Yang Hu, Xuefeng Tan, Cai You, Yuanhua Liu, Ziyi Chen, Xiu-Qin Dong* and Xumu Zhang*
7. Nickel-Catalyzed Enantioselective Hydrogenation of β-(Acylamino)acrylates: Synthesis of Chiral β-Amino Acid Derivatives. Org. Lett. 2017, 19, 5130-5133. https://pubs.acs.org/doi/abs/10.1021/acs.orglett.7b02417
Xiuxiu Li, Cai You, Shuailong Li, Hui Lv* and Xumu Zhang*
6. Enantioselective and Diastereoselective Construction of Chiral Amino Alcohols by Iridium–f-Amphox-Catalyzed Asymmetric Hydrogenation via Dynamic Kinetic Resolution. Org. Lett. 2017, 19, 2548-2551. https://pubs.acs.org/doi/full/10.1021/acs.orglett.7b00844
Weilong Wu, Cai You, Congcong Yin, Yuanhua Liu, Xiu-Qin Dong* and Xumu Zhang*
5. Efficient synthesis of (S,R)-Bn-Yanphos and Rh/(S,R)-Bn-Yanphos catalyzed asymmetric hydroformylation of vinyl heteroarenes. Org. Chem. Front. 2017, 4, 288-291. https://pubs.rsc.org/en/content/articlelanding/2017/qo/c6qo00641h
Biao Wei, Caiyou Chen, Cai You, Hui Lv* and Xumu Zhang*
4. Rhodium-catalyzed enantioselective hydrogenation of α-amino acrylonitriles: an efficient approach to synthesizing chiral α-amino nitriles. Chem. Commun. 2017, 53, 1313-1316. https://pubs.rsc.org/en/content/articlelanding/2017/cc/c6cc09662j
Xiuxiu Li,+ Cai You,+ Yusheng Yang, Fangyuan Wang, Shuailong Li, Hui Lv* and Xumu Zhang* (+Co-first author)
3. Rhodium-Catalyzed Asymmetric Hydrogenation of Tetrasubstituted Cyclic Enamides: Efficient Access to Chiral Cycloalkylamine Derivatives. Adv. Synth. Catal. 2017, 359, 597-602. https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/adsc.201601135
Xiuxiu Li,+ Cai You,+ Hailong Yang, Jinteng Che, Pengyu Chen, Yusheng Yang, Hui Lv* and Xumu Zhang* (+Co-first author)
2. Rhodium‐Catalyzed Desymmetrization by Hydroformylation of Cyclopentenes: Synthesis of Chiral Carbocyclic Nucleosides. Angew. Chem. Int. Ed. 2016, 55, 6511-6514. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201601478
Cai You,+ Biao Wei,+ Xiuxiu Li, Yusheng Yang, Yue Liu, Hui Lv*, Xumu Zhang* (+Co-first author)
1. C-X (X=Br, I) Bond-Tolerant Aerobic Oxidative Cross-Coupling: A Strategy to Selectively Construct β-Aryl Ketones and Aldehydes. Adv. Synth. Catal. 2012, 354, 341-346. https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/adsc.201100782
Mao Chen, Jie Wang, Ziyi Chai, Cai You, Aiwen Lei*
