发表论文:
1. Singhal A, Styers HC, Rub J, Li Z, Torborg SR, Kim JY, Grbovic-Huezo O, Feng H, Tarcan ZC, Sahin Ozkan H, Hallin J, Basturk O, Yaeger R, Christensen JG, Betel D, Yan Y, Chio IIC, de Stanchina E, Tammela T. A classical epithelial state drives acute resistance to KRAS inhibition in pancreas cancer. Cancer Discovery. (2024) July 08.
2. Li Z, Zhuang X, Pan CH, Yan Y, Thummalapalli R, Hallin J, Torborg S, Singhal A, Chang JC, Manchado E, Dow LE, Yaeger R, Christensen JG, Lowe SW, Rudin CM, Joost S, Tammela T. Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma. Cancer Discovery. (2024) 14 (2): 308–325.
3. Gao Y *, Päivinen P *, Tripathi S *, Domènech-Moreno E, Wong IP, Vaahtomeri K, Nagaraj AS, Talwelkar SS, Foretz M, Verschuren EW, Viollet B, Yan Y #, Mäkelä TP. Inactivation of AMPK leads to attenuation of antigen presentation and immune evasion in lung adenocarcinoma. Clinical Cancer Research. (2022) 28 (1): 227–237. （# 唯一通讯作者)
4. Yan Y * and Tammela T #. A MASCOT for mosaic analysis. Proc Natl Acad Sci U S A. (2020) Nov 16; doi.org/10.1073/pnas.2021382117（*第一作者）
5. Gao Y*, Yan Y * #, Tripathi S, Pentinmikko N, Amaral A, Pävinen P, Domènech-Moreno E, Andersson S, Wong IP, Clevers H, Katajisto P, Mäkelä TP #. LKB1 represses ATOH1 via PDK4 and energy metabolism and regulates intestinal stem cell fate. Gastroenterology. (2020) Apr;158(5):1389-1401.e10. doi: 10.1053/j.gastro.（*共同第一作者；#共同通讯作者)
6. Yan Y *, Ollila S, Wong IP, Vallenius T, Palvimo JJ, Vaahtomeri K, Mäkelä TP #. SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signaling. Nature Communications. (2015) Nov 30;6:8979. doi: 10.1038（*第一作者）
7. Marjanovic ND, Hofree M, Chan JE, Canner D, Wu K, Trakala M, Hartmann G, Smith O, Kim J, Evans KV, Hudson A, Ashenberg O, Porter C, Subramanian A, Pitter K, Yan Y, Delroy T, Philips DR, Tsankov A, Shah N, Chaudhary O, Hollmann T, Rekhtman N, Massion PP, Poirier JT, Mazutis L, Lee JH, Amon A, Rudin CM, Jacks T#, Regev A#, Tammela T#. Emergence of a high-plasticity cell state during lung cancer evolution. Cancer Cell. (2020) Aug 10;38(2):229-246.e13. doi: 10.1016/j.ccell.2020.06.012.
8. Ollila S *, Domènech-Moreno E, Laajanen K, Wong IP, Tripathi S, Pentinmikko N, Gao Y, Yan Y, Niemelä EH, Wang TC, Viollet B, Leone G, Katajisto P, Vaahtomeri K, Mäkelä TP #. Stromal loss of Lkb1 drives gastrointestinal tumorigenesis involving the IL-11-Jak/Stat3 pathway. Journal of Clinical Investigation. (2018) Jan 2;128(1): 402-414.doi: 10.1172/JCI93597.
9. Georgiadou M *, Lilja J *, Jacquemet G, Guzman C, Rafaeva M, Alibert C, Yan Y, Sahgal P, Lerche M, Manneville JB, Mäkelä TP, Ivaska J #. AMPK negatively regulates tensin-dependent integrin activity. Journal of Cell Biology. (2017) Apr 3;216(4):1107-1121. doi: 10.1083/jcb.201609066.
10. Nieminen AI, Eskelinen VM, Haikala HM, Tervonen TA, Yan Y, Partanen JI, Klefström J #. Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis. Proc Natl Acad Sci U S A. (2013) May 14;110(20): E1839-48.doi:10.1073/pnas.1208530110.
11. Peng G, Yan Y, Zhu C, Wang S, Yan X, Lu L, Li W, Hu J, Wei W, Mu Y, Chen Y, Feng Y, Gong R, Wu K, Zhang F, Zhang X, Zhu Y, Wu J #. Borna disease virus P protein affects neural transmission through interactions with gamma-aminobutyric acid receptor-associated protein. Journal of Virology. (2008) Dec;82(24):12487-97. doi: 10.1128/JVI.00877-08.
