Teng Y, Huang G*, Yang H*. Unveiling the multifaceted roles of extracellular vesicles in cancer: insights from molecular imaging and engineering strategies. Acta Biochim Biophys Sin (Shanghai). 2025 Aug 8. Epub ahead of print.
Zhang W, Yang Z, Li X, Li D, Liu J, Liu W, Xie W, Liu J, Cheng Y*, Yang H*, Lu X*. Discovery of N-methylguanidine derivatives as a new type of potent pyruvate kinase M2 inhibitor. Bioorg Med Chem Lett. 2025:130264.
Wang J, Liu L, Gao X, Liu X, Dai Y, Mao Z, Huang S, Li J, Wang D, Qi Y, Han Y, Xu Y, Chua CYX, Grattoni A, Xie W*, Yang H*, Huang G*. A novel pathway for stemness propagation and chemoresistance in non-small cell lung cancer via phosphorylated PKM2-loaded small extracellular vesicles. Theranostics 2025; 15(8):3439-3461. [封面论文]
高心雨,毛子俊,黄圣喆,黄钢,杨浩*. 肿瘤干细胞源性的外泌体促进结直肠癌细胞的化疗耐药和侵袭. 中国生物化学与分子生物学报.2024, 40 (8) : 1119-1131. [封面论文].
Li H#, Yang H#, Liu J, Yang H, Gao X, Yang X, Liu Z, Qian Q. Adipose stem cells-derived small extracellular vesicles transport Thrombospondin 1 cargo to promote insulin resistance in gestational diabetes mellitus. Diabetol Metab Syndr. 2024;16(1):105.
Hu J-L, Guo Z-J, Wang C, Yan J, Yang H*. Ovarian serous carcinoma with stomach metastasis: a rare case report and literature review. Journal of International Medical Research. 2024;52(4): 3000605241245000.
Yang H, Zhao X, Liu J, Jin M, Liu X, Yan J, Yao X, Mao X, Li N, Liang B, Xie W, Zhang K, Zhao J*, Liu L*, Huang G*. TNFα-induced IDH1 hyperacetylation reprograms redox homeostasis and promotes the chemotherapeutic sensitivity. Oncogene. 2023, 42(1):35-48.
Chang Y, Gao X, Jiang Y, Wang J, Liu L, Yan J, Huang G*, Yang H*. Alpha-hederin reprograms multi-miRNAs activity and overcome small extracellular vesicles-mediated paclitaxel resistance in NSCLC. Front Pharmacol. 2024; 15:1257941.
Yang H*, Wang J, Huang G*. Small extracellular vesicles in metabolic remodeling of tumor cells: Cargos and translational application. Front Pharmacol. 2022, 13:1009952.
Dai Y, Liu Y, Li J, Jin M, Yang H*, Huang G*. Shikonin inhibited glycolysis and sensitized cisplatin treatment in non-small cell lung cancer cells via the exosomal pyruvate kinase M2 pathway. Bioengineered. 2022, 13(5):13906-13918.
Wang D, Zhao C, Xu F, Zhang A, Jin M, Zhang K, Liu L, Hua Q, Zhao J, Liu J, Yang H*, Huang G*. Cisplatin-resistant NSCLC cells induced by hypoxia transmit resistance to sensitive cells through exosomal PKM2. Theranostics. 2021, 11(6):2860-2875.
Yang H, Zheng H, Pan Y, Zhang W, Yang M, Du H, Yu A, Li P, Chen X, Xie W, Ren K, Zhao Y, Wang T, He X*, Zhou Z*. Quantitative proteomic analysis of the effects of dietary deprivation of methionine and cystine on A549 xenograft and A549 xenograft-bearing mouse. Proteomics. 2021, 21(20):e2100007.
Xu F, Hua Q, Zhang A, Zhang D, Wang Y, Zhao L, Yang H*, Liu J*, Huang G*. LncRNA AC020978 facilitates non-small cell lung cancer progression by interacting with MDH2 and activating AKT pathway. Cancer Sci. 2021, 112(11): 4501-4514.
Yang H*, Xie S, Liang B, Tang Q, Liu H, Wang D, Huang G*. Exosomal IDH1 increases the resistance of colorectal cancer cells to 5-Fluorouracil. J Cancer. 2021, 12(16):4862-4872.
Yang H, Chen Y, Jiang Y, Wang D, Yan J*, Zhou Z*. TP53 mutation influences the efficacy of treatment of colorectal cancer cell lines with a combination of sirtuin inhibitors and chemotherapeutic agents. Exp Ther Med. 2020, 20(2): 1415-1422.
Yang H, Zhu R, Zhao X, Liu L, Zhou Z, Zhao L, Liang B, Ma W, Zhao J, Liu J*, Huang G*. Sirtuin-mediated deacetylation of hnRNP A1 suppresses glycolysis and growth in hepatocellular carcinoma. Oncogene. 2019, 38(25):4915-4931.
常毓真, 杨浩*, 黄钢*. α-常春藤皂苷调控SREBP1/FASN通路抑制非小细胞肺癌的恶性表型. 肿瘤防治研究, 2023, 50(08): 745-752.
杨浩, 解伟, 张坤驰, 陆秀宏. 《生物化学》课程在医学生课程思政教育中的实践和思考 ——以上海健康医学院《生物化学》课程为例. 教育现代化. 2021, 8(26):146-148.
王栋梁,杨浩,宋少莉,刘建军,黄钢.代谢重编程在化疗耐药乳腺癌中的作用机制[J].肿瘤学杂志,2021,27(03):196-201.
主持项目：
国家自然科学基金项目面上项目，PKM2苏木化修饰调节非小细胞肺癌起始细胞介导的耐药生态位的机制研究，2024年1月-2027年12月
上海市自然科学基金面上项目，小细胞外囊泡传递磷酸化IGFBP3调控结直肠癌代谢稳态及化疗敏感性的基础研究，2023年4月-2026年3月
国家自然科学基金项目青年科学基金项目，SIRT1去乙酰化IDH1调节结直肠癌糖代谢重编程及耐药性的机制研究，2020/1-2022/12
上海市教委上海高校青年教师培养资助计划，课程思政改革要求下医学生物化学课程的课堂教学设计，2019/7-2020/12
上海健康医学院种子基金项目（自然科学类），乙酰化的hnRNP A1通过PKM2调节肝癌细胞糖代谢的机制研究，2018/01-2019/12
上海健康医学院师资人才百人库项目，异柠檬酸脱氢酶1在KRAS突变结直肠癌化疗耐药中的功能研究，2019/01-2019/12
上海市A类“晨光计划”项目，IDH1及其去乙酰化在KRAS突变结直肠癌化疗耐药中的作用研究，2020/01-2022/12
上海健康医学院科研骨干校外导师制（Academic Mentorship for Scientific Research Cadre Project），去乙酰化酶在5-氟尿嘧啶耐药的结直肠癌中的功能与机制研究，2021/01-2023/12
上海市教委“教师专业发展工程”的产学研践习计划，基于肿瘤外泌体中代谢成分进行肿瘤微环境监测的的分子影像技术开发，2021年3月-2022年2月