Published articles and reviews

2025

69.Nickel-catalyzed amination of aryl halides: An exogenous ligand-free approach to primary arylamines using TMSN₃

Jiawei Huang , Xiaoman Li , Zhigang Lei *, Liang Xu *, Shuai Liu*

Journal of Catalysis, 2025: 116284.

68.Electrochemical Strategy for the Radical Fluoroacetylation of Sulfoximines from Fluorinated Alkyl Carboxylic Acids

XiaomanLi, JiaweiHuang, HuanhuanSong, LiangXu, JichangLiu*, MingyouHu*, YuWei*

Org. Lett. 2025, 27, 16, 4164–4169

67.Photo-induced energy transfer mediated O₂-initiated deboronative generation of alkyl radicals from alkyl boronic acids and its application in radical Smiles rearrangement

Jinpeng Wu, Yongsheng Tian, Xue Zhao, Shuai Liu*, Liang Xu*, Huanhuan Song*

Org. Chem. Front., 2025

66.Electrochemically enabled Nickel-catalyzed controllable synthesis of monoaryl 

or diaryl amines from aryl halides and trimethylsilyl azides

Jiawei Huang, Xiaoman Lia, Xue Zhao, Yu Wei*, Liang Xu*

Green Chem., 2025

65.Electrochemical C(sp3)–S bond cleavage of thioethers: an approach for simultaneous utilization of carbon- and sulfur-fragments

Jiawei Huang, Xiaoman Li, Liang Xu*, andYuWei *

Org. Chem. Front., 2025

64.Electrochemical strategies for N-alkylation and N-acylation of NH-sulfoximines via the decarboxylation and deoxygenation of carboxylic acids

Xiaoman Li, Jiawei Huang, Ji-Xing Zhao, Liang Xu, Ping Liu*, Jichang Liu*, Yu Wei*

Org. Chem. Front., 2025

63.Electrochemical alkylation of C(sp2)–H bonds via halogen-atom transfer (XAT) from alkyl iodides

Changqiong Ke, Qing Tian, Qianqian Zhai, Qirui Dai, Liang Xu, Yu Wei*, Shuai Liu*

Org. Biomol. Chem., 2025, 23, 3336-3341

62.Engineering Air-Stable Triarylmethyl Radicals with One Pyrrole Ring

Pengfei Dong, Zenghui Li, Kaixing Gu, Liang Xu*, Yu Wei*, Jing Wang, Ling Yue, and Bin Rao*

• • Org. Lett. 2025, 27, 2, 686–691
  • • 
      

2024

61.Diverse Synthesis of Arene-Fused [n.1.1]-Bridged Molecules via Catalytic Cycloaddition and Rearrangement Reactions

Tao Yu, Xue Zhao, Zaicheng Nie, Lulu Qin, Zhengwei Ding, Liang Xu, Pengfei Li*

Angew. Chem. Int. Ed. 2025, e202420831

60.Diastereoselective Homocoupling of Benzylic C(sp3)–H Bonds Enabled by Halogen Transfer

Xirong Liu, Xin An, Xue Zhao, Shuda Luo, Liang Xu*, and Miao Zhan*

Org. Lett. 2024, 26, 43, 9257–9262

59.Regio- and Diastereoselective Synthesis of Polysubstituted Piperidines Enabled by Boronyl Radical-Catalyzed (4+2) Cycloaddition

Zhengwei Ding, Zhijun Wang, Yingying Wang, Xicheng Wang, Yuanji Xue, Ming Xu, Hailong Zhang*, Liang Xu*, and Pengfei Li*

Angew. Chem. Int. Ed. 2024, 63, e202406612

58.C–Cbondcleavage arylation and alkenylation of cyclobutanone oxime ethers via photoredox/ nickel catalysis

Chenglin Peng, Yingru Tang, Shili Sun, Yu Wei, Weiji Zhou, Li-Na Guo*, Liang Xu*, Shuai Liu*

Org. Chem. Front., 2024

57.Vinylcyclopropane-Cyclopentene (VCP-CP) Rearrangement Enabled by Pyridine-Assisted Boronyl Radical Catalysis

Ting Li, Lanfeng Wei, Zhijun Wang, Xinyu Zhang, Jinbo Yang, Yu Wei*, Pengfei Li*, Liang Xu*

Org. Lett. 2024

56.Ligand-Enabled ortho-Selective C−H Olefination of Tertiary Aniline Derivatives

Chunchen Yuan*, Changbo Jia, Xinyu Zhang, Wenlong Zhang, Yang’en You, Xiaolong Xu, Lei Zhu, Yiliang Chen, Yongping Dong*, Liang Xu*

Org. Lett. 2024, 26, 4877−4881

55.A pyridine-boryl radical mediated cascade reaction towards the synthesis of indolizines: a computational mechanistic analysis

Xinyu Zhang, Xiangxue Cao, Lanfeng Wei, Zhijun Wang, Yu Wei*, Liang Xu*, Genping Huang*

Org. Chem. Front., 2024

54.Benzoselenadiazole-Functionalized H-Bonded Arylamide Foldamers:Solvent-Responsive Properties and Helix Self-Assembly Directed by Chalcogen Bonding in Solid State

Chuan-Zhi Liu*, Chi Zhang, Chang-Gen Li, Hui-Bin Chen, Wen Yang, Zhong-Yi Li, Zhi-Yuan Hu, Liang Xu*, Bin Zhai*, Zhan-Ting Li

Chemistry–A European Journal (2024): e202401150.

53.Iridium-catalyzed doubly stereoconvergent allylic alkylation of racemic a-boryl organozinc reagents

Jinhui Han, Xirong Liu, Hao Jin, Panchi Guo, Liang Xu, Pengfei Li*, Miao Zhan*

Chem Catalysis, 2024

52.可见光诱导二氢喹唑啉酮碳碳键断裂与三氟甲基取代烯烃的脱氟烷基化反应研究

曹香雪, 贾雅会,  殷世纪, 徐亮, 韦玉*, 宋欢欢*

有机化学 2024

51.Avisible-light-induced bromine radical initiates direct C–H alkylation of heteroaromatics

Xiangxue Cao, Lanfeng Wei*, Jinbo Yang, Huanhuan Song*, Yu Wei*.

Org. Biomol. Chem., 2024, 22, 1157-1161

50.四丁基三溴化铵促进的有机硼酸在无过渡金属条件下的脱硼硒化、溴化和羟基化反应

田永盛, 魏斓枫, 黄嘉为, 韦玉, 徐亮*, 刘帅*

有机化学 2024

49.Catalytic Aerobic Photooxidation of Phosphines using Four-coor dinated Organoboron Compounds as Photocatalysts

Synlett, 2024.

2023

48.Electrochemical Oxidative Dehydrogenative Coupling of Sulfoximines to Construct N-sulfenyl and N-phosphinyl Sulfoximines

Xiaoman Li, Jiawei Huang, Liang Xu*, Jichang Liu*, Yu Wei*.

Advanced Synthesis & Catalysis, 2023.

47.Organoboron/iodide-catalyzed photoredox N-functionalization of NH-sulfoximines/sulfonimidamides

Jiawei Huang, Xiaoman Li, Yu Wei, Zhigang Lei*, and Liang Xu*. 

Chem. Commun., 2023, 59, 13643-13646

46.Visible light-induced metal-free chemoselective oxidative cleavage of benzyl C–heteroatom (N, S, Se) bonds utilizing organoboron photocatalysts

Lanfeng Wei, Wenbo Bai, Zhiyan Hu, Zhiyong Yang*, and  Liang Xu*. 

Chem. Commun. 2023, 59, 13344-13347

45.Fe-Catalyzed Alkylazidation of α-Trifluoromethylalkenes: An Access to Quaternary Stereocenters Containing CF3 and N3 Groups

Shuai Liu, Lu Zhang, Liang Xu, Pin Gao, Xin-Hua Duan, and Li−Na Guo*

Organic Letters 2023 25 (8), 1336-1341

44.Visible Light-Mediated Organoboron-Catalyzed Metal-Free Synthesis of Silanols from Silanes. (Invited contribution)

Yang, Jinbo, Xiangxue Cao, Lanfeng Wei, Jianshu Zhang, Jinli Zhang, Ping Liu, Liang Xu*, and Pengfei Li*.

Molecules 2023, 28, 4082.

43. Chromium-Catalyzed Diastereoselective Synthesis of Conformationally Constrained Spirotetrahydroquinolines

Changpeng Chen, Zhijun Wang, Sha Wang, Liang Xu*, and Xiaoming Zeng*

Organic Letters 2023 25 (23), 4241-4246

42. Nickel-Catalyzed Negishi Cross-Coupling of Alkyl Halides, Including Unactivated Tertiary Halides, with a Boron-Stabilized Organozinc Reagent

Panchi Guo, Hao Jin, Jinhui Han, Liang Xu, Pengfei Li*, and Miao Zhan*

Organic Letters 2023 25 (8), 1268-1273

41. Selective [2σ + 2σ] Cycloaddition Enabled by Boronyl Radical Catalysis: Synthesis of Highly Substituted Bicyclo[3.1.1]heptanes

Tao Yu, Jinbo Yang, Zhijun Wang, Zhengwei Ding, Ming Xu, Jingru Wen, Liang Xu, and Pengfei Li*

Journal of the American Chemical Society 2023 145 (7), 4304-4310

40. Additive-Free Transfer Hydrogenative Direct Asymmetric Reductive Amination Using a Chiral Pyridine-Derived Half-Sandwich Catalyst

Yuan Gao, Zhijun Wang, Xinyu Zhang, Min Zhao, Shuai Zhang, Chao Wang, Liang Xu*, Pengfei Li *

Angew. Chem. Int. Ed. 2023, e202303709.

39. 异喹啉-3-羧酸根螯合的B,B-二芳基四配位硼络合物的合成 (Invited contribution)

田维娜, 徐亮, 韦玉*, 李鹏飞*

有机化学 2023, 43(5): 1792-1798.

38. α-酮酸与硫酚的电化学脱羧偶联: 一种合成硫代酸酯的新方法. 

黄嘉为, 李潇漫, 徐亮, 韦玉*

有机化学 2023, 43(2): 756-762.

37. Photoinduced oxidation of benzylic boronic esters to ketones/aldehydes via α-borylalkyl radicals. 

Wang, Z.; Wei, L.; Liu, J.*; Wei, Y.*; Xu, L.*

Org. Chem. Front. 2023, 10, 104-108

 

36. Three-Component Oxychalcogenation of Alkenes under Metal-Free Conditions: A Tetrabutylammonium Tribromide-Catalyzed System. 

Huang, J.; Li, X.; Xu, L.; Wei, Y.*

J. Org. Chem. 2023, 88, 3054-3067

 

2022

35. Diboron(4)-Catalyzed Remote [3+2] Cycloaddition of Cyclopropanes via Dearomative/Rearomative Radical Transmission through Pyridine

Ming Xu,  Zhijun Wang,  Zhaohui Sun,  Yizhao Ouyang,  Zhengwei Ding,  Tao Yu,  Liang Xu,  Pengfei Li*

Angew. Chem. Int. Ed. 2022, 61, e202214507; Angew. Chem. 2022, 134, e202214507.

34. Catalysis with Diboron(4)/Pyridine: Application to the Broad-Scope [3 + 2] Cycloaddition of Cyclopropanes and Alkenes.

Ding, Z.; Liu, Z.; Wang, Z.; Yu, T.; Xu, M.; Wen, J.; Yang, K.; Zhang, H.; Xu, L.*; Li, P.*, 

Journal of the American Chemical Society 2022, 144, 8870-8882

33.  Synthesis of acridines via copper-catalyzed amination/annulation cascades between arylboronic acids and anthranils.  (Invited contribution)

Li, Y.; Xu, L.*; Wei, Y.*

Org. Biomol. Chem. 2022, 20, 9742-9745

 

32.  Copper-Catalyzed Reactions of Alkenyl Boronic Esters via Chan–Evans–Lam Coupling/Annulation Cascades: Substrate Selective Synthesis of Dihydroquinazolin-4-ones and Polysubstituted Quinolines. 

Li, Y.; Cao, Z.; Wang, Z.; Xu, L.; Wei, Y.*

Organic Letters 2022, 24, 6554-6559

31.  Synthesis of β-Arylseleno Sulfoximines: A Metal-Free Three-Component Reaction Mediated by Tetrabutylammonium Tribromide.

Li, X.; Huang, J.; Xu, L.; Liu, P.; Wei, Y. *

J. Org. Chem. 2022, 87, 10684-10697

 

30.  A nickel/organoboron catalyzed metallaphotoredox platform for C(sp2)–P and C(sp2)–S bond construction. 

Zhu, Y.; Zu, W.; Tian, Q.; Cao, Z.; Wei, Y.; Xu, L.*

Org. Chem. Front. 2022, 9, 1070-1076

 

29.  The Synthesis of α-Keto Acetals from Terminal Alkynes and Alcohols via Synergistic Interaction of Organoselenium Catalysis and Electrochemical Oxidation. 

Ding, D.; Xu, L.; Wei, Y.*

J. Org. Chem. 2022, 87 , 4912-4917

  

28.  Design and Synthesis of Tunable Chiral 2,2′-Bipyridine Ligands: Application to the Enantioselective      Nickel-Catalyzed Reductive Arylation of Aldehydes. 

Zhang, S.; Perveen, S.; Ouyang, Y.; Xu, L.; Yu, T.; Zhao, M.; Wang, L.; Song, P.; Li, P.*

Angewandte Chemie International Edition. 2022, 61 (20), e202117843

27.  Electrochemical utilization of methanol and methanol-d4 as a C1 source to access (deuterated) 2,3-dihydroquinazolin-4(1H)-one. 

Liu, M.; Xu, L.*; Wei, Y.*

Chinese Chemical Letters 2022, 33 (3), 1559-1562.

2021

26.  Radical-mediated vicinal addition of alkoxysulfonyl/fluorosulfonyl and trifluoromethyl groups to aryl alkyl alkynes. 

Dong, X.; Jiang, W.; Hua, D.; Wang, X.; Xu, L.*; Wu, X.*

Chem. Sci. 2021, 12, 11762-11768.

 

25.  可见光诱导下四丁基三溴化铵催化的苄位碳氢键氧化反应 . 

代鹏程，徐亮 * 

有机化学 , 2021, 41(12): 4690-4695.

24.  Synthesis of quinazolin-4(3H)-ones via electrochemical decarboxylative cyclization of α‑keto acids with 2-aminobenzamides. 

Tian,Q.; Zhang, J.*; Xu, L.*; Wei, Y.*

Molecular Catalysis 2021,  500, 111345.

23.  Visible-light-mediated organoboron-catalysed metal-free dehydrogenation of N-heterocycles using molecular oxygen. 

Wei, L.; Wei, Y.; Zhang, J.*; Xu, L.*

Green Chemistry 2021, 23 (12), 4446-4450.

22.  Development of a Tunable Chiral Pyridine Ligand Unit for Enantioselective Iridium-Catalyzed C–H Borylation. 

Song, P.; Hu, L.; Yu, T.; Jiao, J.; He, Y.; Xu, L.*; Li, P.*, 

ACS Catalysis 2021, 11 (12), 7339-7349.

2020

21.  Visible-Light-Mediated Aminoquinolate Diarylboron-Catalyzed Metal-Free Hydroxylation of Organoboronic Acids under Air and Room Temperature. 

Wei, L.; Zhang, J.*; Xu, L.*, 

ACS Sustain. Chem. Eng. 2020, 8 , 13894-13899.

20.  Dual aminoquinolate diarylboron and nickel catalysed metallaphotoredox platform for carbon–oxygen bond construction

 Weisai Zu, Craig Day, Lanfeng Wei, Xin Jia* and Liang Xu *

Chem.Commun. 2020, 56 (59), 8273-8276.

19.  tert-Butyl Bromide-Promoted Intramolecular Cyclization of 2-Arylamino Phenyl Ketones and Its Combination with Cu-Catalyzed C–N Coupling: Synthesis of Acridines at Room Temperature

Zifeng Cao, Yuan Zhu, Xiaoman Li, Yang He, Jinli Zhang*, Liang Xu, and Yu Wei*

J. Org. Chem. 2020, 85 (15), 10167-10174.    

 

18.  Dual Catalytic Platform for Enabling sp3 a C–H Arylation & Alkylation of  Benzamides

Alexander W. Rand, Hongfei Yin, Liang Xu, Jessica Giacoboni, Raul Martin-Montero, Ciro Romano, John Montgomery*, and Ruben Martin*

ACS Catalysis, 2020, 10, 4671.

17.  Total Synthesis of Prostratin, a Bioactive Tigliane Diterpenoid: Access to Multi-Stereocenter Cyclohexanes from a Phenol

 Guanghu Tong, Zhengwei Ding, Zhi Liu, You-Song Ding, Liang Xu*, Hailong Zhang, and Pengfei Li*

Journal of Organic Chemistry, 2020, 85, 4813.

 16. 二苯甲酮腙与芳基氯化物及芳基硼酸的碳氮键偶联反应

姚丹丹，张金利*，徐亮*

有机化学，2020, 40, 1673. 

15.  Electrochemical synthesis of sulfinic esters from alcohols and thiophenols

Yang He, Jinli Zhang*, Liang Xu*, Yu Wei*, 

Tetrahedron Lett. 2020, 61 (12), 151631. 

14.  Copper‐catalyzed synthesis of N‐aryl acridones from 2‐amino benzophenones and aryl boronic acids via sequential double oxidative C–N coupling

Yang He, Liang Xu, Jinli Zhang*, Yu Wei*

Applied Organometallic Chemistry, 2020, 34, e5316.

2019

13.  Hydrochlorination of Acetylene Over the Activated‐Carbon‐Supported Au Catalysts Modified by N − P − O‐Containing Ligand

Chuanming Zhang, Haiyang Zhang*, Yanqin Li, Liang Xu*,  Jian Li,  Linfeng Li,  Ming Cai, Jinli Zhang*

ChemCatChem 2019, 11, 3441.

12.  Unsymmetrical Diboron Reagents: Application in Borylation Reactions of Unsaturated Bonds

Siyi Ding, Liang Xu, Zongcheng Miao*

Molecules 2019, 24, 1325. 

11.  Chemoselective N-arylation of aminobenzene sulfonamides via copper catalysed Chan–Evans–Lam reactions

Zu Weisai, Liu Shuai, Jia Xin*, Xu Liang*

Org. Chem. Front., 2019,6, 1356-1360

10.  One-Pot, Multistep Reactions for the Modular Synthesis of N, N'-Diarylindazol-3-ones

Liu Shuai, Xu Liang, Wei Yu*

J. Org. Chem. 2019, 84, 3, 1596–1604

9.  One-pot propagation of  (Hetero)Arylamines: Modular synthesis of diverse Amino-di(hetero)arylamines

Liang Xueting, Xu Liang, Li Cuihua*, Jia Xin, Wei Yu*

Tetrahedron 2019 , 75, 721-731. 

2018

  8.  Highly Selective β-Hydride Elimination in the Pd-Catalyzed Cross-Coupling of N-Tosylhydrazones with Benzyl Bromides 

Sun Zhenze, Du Chaoqun, Liu Ping*, Wei Yu*, Xu Liang, Dai Bin

ChemistrySelect 2018, 3, 900-903; 

7.  Decarboxylative Borylation: New Avenues for the Preparation of Organoboron Compounds

Xu Liang*

European Journal of Organic Chemistry 2018, 2018, 3884-3890. 

6.  Copper-Catalyzed N-Arylation with Boronic Acid Pinacol Esters

Liu Shuai, Xu Liang*

Asian Journal of Organic Chemistry 2018, 7, 1856-1863.

2017

5.  Recent advances in catalytic C − H borylation reactions

Xu Liang, Wang Guanghui, Zhang Shuai, Wang Hong, Wang Linghua, Liu Li, Jiao Jiao, Li Pengfei*

Tetrahedron 2017, 73, 7123-7157. 

4.  Mechanistic Insights on a Metal-Free Borylative Cyclization of Alkynes Using BCl3: A Theoretical Investigation 

Wei Yu, Liu Dongwei, Qing Xinlin, Xu Liang*

Asian Journal of Organic Chemistry 2017 , 6, 1575-1578. 

3. Copper-Catalyzed C–N Bond Exchange of N-Heterocyclic Substituents around Pyridine and Pyrimidine Cores

Tao Sheng, Ji Enhui, Shi Lei, Liu Ning*, Xu Liang*, Dai Bin*

Synthesis 2017, 49, 5120-5130. 

2. Pd(0)-Catalyzed Tandem One-Pot Reaction of Biphenyl Ketones/Aldehydes to the Corresponding Di-substituted Aryl Olefins

Liu Yang, Liu Ping, Liu Yan*, Wei, Yu*

Chinese Journal of Chemistry 2017 , 35, 1141-1148. 

    

1. Chemoselective N-arylation of aminobenzamides via copper catalysed Chan–Evans–Lam reactions

Liu Shuai, Zu Weisai, Zhang Jinli*, Xu Liang*

Organic & Biomolecular Chemistry 2017 , 15, 9288-9292. 

Book chapter
[1]      Xu, L.; Zhang, S.; Li, P.*, Di- and Polyboron Compounds: Preparation and Chemoselective Transformations. In Boron Reagents in Synthesis, American Chemical Society: 2016; Vol. 1236, pp 415-444.
[2]      Xu, L., Decarbonylative/Decarboxylative Borylation, In Science of Synthesis: Advances in Organoboron Chemistry towards Organic Synthesis, 2019, 271. @Georg Thieme Verlag KG, Stuttgart, Germany.

Patents
[1]      芳胺基苯甲酰胺类化合物及 N- 芳基 - 芳胺基苯甲酰胺类化合物的制备方法： ZL 2017 1 0686306.0