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杨占会 教授    

杨占会


男,博士,教授,博士生导师


电话:010-64435565;


电子邮箱:zhyang@mail.buct.edu.cn;

 

导师寄语


   “人生的道路虽然漫长,但紧要处常常只有几步,特别是年轻的时候。”


教育经历:


   2010-2015年:北京化工大学有机化学系,获博士学位;


   2006-2010年:北京化工大学应用化学系,获学士学位。



工作经历


2024.01 - 至今   北京化工大学,化学学院,教授,博士生导师 


2018.01-2023.12  北京化工大学,理学院,副教授;


2017.11-2018.01   北京化工大学,理学院,讲师;


2016.08-2017.08   美国威斯康辛大学麦迪逊分校,药学院,访问学者


2015.07-2017.10:北京化工大学,化学工程与技术,博士后。




主要研究领域


(1)过渡金属催化:金属卡宾参与的环加成反应、金属氢化物参与的转移氢化反应;


(2)绿色化学:以水作为溶剂的新反应开发;


(3)有机合成方法学:简单、高效、实用的新方法开发。


主持或参与课题及项目研究情况


(1)    主持:2024-2027 国家自然科学基金面上项目:基于生成α-硫羰基卡宾的新途径构筑手性硫杂环;


(2)    主持:2025-2027北京市自然科学基金面上项目:基于新型手性Mn(I)催化剂不对称催化合成氧杂环丁烷;


(3)    参与:2022-2025 国家重点研发计划课题:高纯手性稀土有机配合物试剂合成技术开发及应用;


(4)    主持:2020-2022北京市自然科学基金面上项目:基于新型铱催化剂的水相不对称转移氢化;


(5)    主持:2017-2019国家自然科学青年基金:基于硫羰基卡宾的五元和七元硫杂环合成;


(6)    主持:2015-2016中国博士后科学基金项目:硫代-Staudinger环加成的关环机理研究;


(7)    主持多项企业技术开发、技术服务项目。




发表论文情况


累计发表学术论文70余篇(第一作者、通讯作者),其中SCI收录论文70余篇。代表性论文如下


[26] Yujie Zhang, Kangjia Zhang, Jiaxi Xu, Zhanhui Yang*. Iridium-catalyzed N-methylation of drug molecules. Green Chem. 2025, 27, 5136-5148.


[25] Cunzhi Chen, Xinru Zhang, Hongguang Du, Jiaxi Xu, and Zhanhui Yang*.  Enantioselective Skeletal Transformation of 1,2,3-Thiadiazoles to Dihydrothiophenes. J. Org. Chem. ASAP. DOI:  https://doi.org/10.1021/acs.joc.5c02611


[24] Cunzhi Chen, Hongguang Du*Jiaxi Xuand Zhanhui Yang*Origins of Regio-and Enantiocontrol in Rhodium-Catalyzed Synthesis of Alkylidene Dihydrothiophenes from 1, 2, 3-Thiadiazoles and Allenes. J. Org. Chem. 2025, 9011124–11131.


[23] Cunzhi Chen, Youwei Chen, Hongguang Du, Jiaxi Xu, Zhanhui Yang*Enantioselective and Regiodivergent Skeletal Transformations of 1,2,3-Thiadiazoles to Alkylidene DihydrothiophenesOrg. Lett. 2025, 27, 16, 4337–4342.


[22] Liu Li, Hao Wei, Zhanhui Yang, Jiaxi Xu*. Ce(OTf)3-Catalyzed Asymmetric 6π Cyclization of Triaryldivinyl Ketones. Org. Lett2025. ASAP.  https://doi.org/10.1021/acs.orglett.5c01081


[21] Cunzhi Chen, Kang Lv, Youwei Chen, Hongguang Du, Jiaxi Xu, Tao Liu*, and Zhanhui Yang*Catalytic Enantioselective (3+2) Annulations of Nucleophilic Thioacyl Rh(I)-Carbenes with Achmatowicz Rearrangement Products. ACS Catal. 2024, 14, 11, 8949-8957.


[20] Yujie Zhang, Shukui Shi, and Zhanhui Yang*Thiourea-Mediated Stereospecific Deoxygenation of Cyanoepoxides to Access Highly Diastereopure Alkenyl Nitriles. J. Org. Chem2024, 89, 4, 2748-2758.


[19] Tingting Wang, Rui Miao, Renshi Luo, Jiaxi Xu, Zhanhui Yang*. Furan-2-yl Anions as γ-Oxo/Hydroxyl Acyl Anion Equivalents Enabled by Iridium-Catalyzed Chemoselective Reduction. Org. Lett. 2023, 25, 4705-4710.


[18] Jing Wang, Tingting Wang, Hongguang Du, Ning Chen*, Jiaxi Xu, Zhanhui Yang*. Accessing para-Alkylphenols via Iridium-Catalyzed Site-Specific Deoxygenation of Alcohols. J. Org. Chem. 2023, 88, 12572-12584. 

 


[17] Cunzhi Chen, Shuyan Fang, Ziyang Dong, Jiaxi Xu, Zhanhui Yang* Catalytic Diastereospecific and Enantioselective (3+2) Transannulations of 1,2,3-Thiadiazoles with Strained Norbornene Derivatives. Org. Lett. 2022, 24, 2110–2114.


[16] Ziyang Dong, Meng-Yao Ma, Jiaxi Xu, Zhanhui Yang*. Catalytic (3 + 2) umpolung annulations of α-thioacyl carbenes with aryl isothiocyanates. Chem. Commun. 2022, 58, 7980-7983.


[15] Yang Chen, Tingting Wang, Hongguang Du*, Jiaxi Xu, Zhanhui Yang*. Proton-Mediated Practical Synthesis of McGeachin-Type Bisaminals. Synthesis. 2021, 53, 2828-2840.

Graphical Abstract


[14] Dong Xu, Yang Chen, Changmeng Liu, Jiaxi Xu, Zhanhui Yang*. Iridium-catalyzed highly chemoselective and efficient reduction of nitroalkenes to nitroalkanes in water. Green Chem. 2021, 23, 6050-6058.


[13] Shiyi Yang, Weiping Tang, Zhanhui Yang*, Jiaxi Xu*. Iridium-catalyzed highly efficient and site-selective deoxygenation of alcohols in water. ACS Catal. 2018, 8, 9320–9326.


[12] Zhicheng Fu, Wenhao Yuan, Ning Chen, Zhanhui Yang*, Jiaxi Xu*. Na2S2O8-mediated efficient synthesis of isothiocyanates from primary amines in water. Green Chem. 2018, 20, 4484–4491.


[11] Zhanhui Yang, Jiaxi Xu*. Insights on β-Sultam Ring Formation in the Sulfa-Staudinger Cycloadditions. J. Org. Chem. 2014, 79, 10703–10708.

[10] Zhanhui Yang, Jiaxi Xu*. Synthesis of Benzo-γ-sultams via the Rh-catalyzed Aromatic C–H Functionalization of Diazosulfonamides. Chem. Commun., 2014, 50, 3616–3618.

[9] Zhanhui Yang, Ning Chen, Jiaxi Xu*. Substituent-Controlled Annuloselectivity and Stereoselectivity in the Sulfa-Staudinger Cycloadditions. J. Org. Chem., 2015, 80, 3611–3620.

[8] Zhanhui Yang, Wei Xu, Qiuyue Wu, and Jiaxi Xu*. Aminoxidation of Arenethiols to N-Chloro-N-sulfonyl Sulfinamides. J. Org. Chem., 2016, 81, 3051–3057.

[7] Zhanhui Yang, Wei He, Baoxiang Cheng, Jiaxi Xu*. Stereochemistry and mechanistic insight in the [2k + 2i + 2i] annulations of ketenes and imines. J. Org. Chem. 2016, 81, 4506-4515.

[6] Zhanhui Yang, Zhongpeng Zhu, Renshi Luo, Xiang Qiu, Ji-tian Liu, Jing-Kui Yang and Weiping Tang*. Iridium-catalyzed Highly Efficient Chemoselective Reduction of Aldehydes in Water using Formic Acid as the Hydrogen Source. Green Chem. 2017, 19, 3296-3301 (Z.Y. and Z.Z. contributed equally).

[5] Zhanhui Yang, Renshi Luo, Zhongpeng Zhu, Xuerong Yang and Weiping Tang*. Harnessing the Reactivity of Iridium Hydrides by Air: Iridium-Catalyzed Oxidation of Aldehydes to Acids in Water.Organometallics, 2017, 36, 4095–4098.

[4] Ji-tian Liu, Shiyi Yang, Weiping Tang, Zhanhui Yang* and Jiaxi Xu*. Iridium-catalyzed efficient reduction of ketones in water with formic acid as a hydride donor at low catalyst loading. Green Chem., 2018, 20, 2118-2124.

[3] Zhicheng Fu, Wenhao Yuan, Ning Chen, Zhanhui Yang* and Jiaxi Xu*. Na2S2O8-mediated efficient synthesis of isothiocyanates from primary amines in water. Green Chem., 2018, 20, 4484–4491.

[2] Shiyi Yang, Weiping Tang, Zhanhui Yang* and Jiaxi Xu*. Iridium-catalyzed highly efficient and site-selective deoxygenation of alcohols in water. ACS Catal., 2018, 8, 9320–9326.

[1] Ziyang Dong, Yang Chen, Zhiheng Yang, Zhanhui Yang* and Jiaxi Xu*. A Tandem Sulfonylation and Knoevenagel Condensation for the Preparation of Sulfocoumarin-3- carboxylates. Synthesis, 2019, DOI: 10.1055/s-0037-1611703. (Z.D. and Y.C. contributed equally)


招生专业

有机化学相关专业。需具有扎实的化学理论基础,具有较强的中英文写作能力。


招生要求

(1)态度端正,作风正派;

(2)踏实能干,吃苦耐劳;

(3)尊师重道,青出于蓝。