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2025

     22.  Miao, H.; Sun, Q.; Zheng, W.; Ye, S.; Tang, L.; Cheng, T.; Tang, X.-J.; Li, X. Y.*; Zhang, D. S.*; Zhang, Z. K.* Green Synth. Catal. 2025, DOI: 10.1016/j.gresc.2025.11.001.

     21.  Li, C.†; Li, X. Y.†; Li, J.†; Wang, Z.; Ouyang, D.; Jiao, N.*; Song, S.* Direct regioselective C-3 halogenation of pyridines. Nat. Synth. 2025, https://doi.org/10.1038/s44160-025-00915-3.(†These authors contributed equally.)

     20.   Xu, B.; Gao, Z.; Liu, C.; Zhang, J.; Li, J.*; Li, X. Y.*;  Hu, T. J.*Asymmetric Access to Phosphinates via Nickel-Catalyzed Hydrophosphorylation of Alkynes. ACS Catal. 2025, 15, 18623−18630.

     19.   Du, T.; Xie, Y. Z.*; Qin, Q.; Yin, K.; Li, J.*; Li, X. Y.*; Zhou, Z. J.* Visible-Light-Excited Lewis Acid Catalyzed Intermolecular [2σ + 3π] Photocycloadditions. Org. Lett. 2025, 27, 11384−11390.

     18.   Li, T.-Z.; Tian, C.-C.; Chen, W.; Zou, Z.-Y.; Yang, J.-L.; Liu, F.-X.; Li, X. Y.*; Zhang, H.-H.*; Shi, F. * Photoredox/Nickel-Cocatalyzed Asymmetric C–O and C–S Couplings for Atroposelective Synthesis of N-Heterobiaryls. Angew. Chem. Int. Ed. 2025, e202516584.  

     17.   Du, T.; Qin, Q.; Li, J.; Shen, Y.; Wang, Z.; Yin, K.*; Li, X. Y.*; Li, J.*; Zhou, Z. J.* Rhodium-catalyzed cycloaddition of bicyclo[1.1.0] butanes with N,N’-cyclic azomethine imines: en route to fused diaza-3D scaffolds. Org. Chem. Front. 2025, 12, 6834–6840.    

     16.    Yang, H.; Li, X. Y.* Decarboxylative Alkylation of Difluoroenoxysilanes via Visible Light-Excited EDA Complex. Eur. J. Org. Chem. 2025, 28, e202500540.

     15.    Hai, J.; Li, H.; Li, Y.; Li, X. Y.* Green-Light Photocatalytic Synthesis of Non-Proteinogenic Isothiocyanate-Decorated Amino Acids from Lysine Residues and Carbon Disulfide. Adv. Synth. Catal. 2025, 367, e70002.

     14.    Wu, F.; Huang, K.; Cen, Z.; Yan, C.; Kan, Y.*; Li, X. Y.*; Wu, X.Y.* Diastereo- and Enantioselective Allylation of α‑Hydroxy Ketones Enabled by Palladium/Borinic Acid Dual Catalysis. ACS Catal. 2025, 15, 8586−8598.

     13.    Wan, Z.; Gu, J.;Lu,  Y.; Tian, X.; Zeng, Z.; Yan, Y.; Li, X. Y.*; Zhuang, D.*; Li, Z. Y.* Selective Benzylic Cross-Dehydrogenative Arylation and α,β Dehydrogenation Under Mild Conditions. Org. Chem. Front. 2025, 12, 3594–3605.

     12.    Cheng, Z.; Huang, K.; Wang, C.; Chen, L.; Li, X. Y.; Hu, Z.; Shan, X.; Cao, P.-F.; Sun, Ha.; Chen, W.; Li, C.; Zhang, Z.; Tan, H.; Jiang, X.; Zhang, G.; Zhang, Z.; Lin, M.; Wang, L.; Zheng, A.; Xia, C.*; Wang, T.; Song, S.; Shu, X.; Jiao, N.* Catalytic remodeling of complex alkenes to oxonitriles through C=C double bond deconstruction. Science 2025, 387, 1083–1090.

     11.    Qiu, S.; Yu, X.; Guo, H.; Li, J.*; Li, X. Y.*; Xu, P.* Photocatalytic Radical Bis(trifluoromethyl)carbinolation of Alkenes and Heteroarenes. Angew. Chem. Int. Ed. 2025, e202424757.

     10.    Ling, S.; Hai, J.; Li, X. Y.* Visible-light-mediated C–S bond activation in cysteine derivatives with quinoxalinones for the synthesis of heteroaryl amino acids. Org. Chem. Front. 2025, 12, 2018–2024.

     9.      Fei, Y.; Zhou, Z.; Ni, Z.; Peng, X.; Cui, L.*; Zhou, Z.; Li, X. Y.*; Li, C.; Jia, X.; Li, J.* Chemoselective Construction of Polycyclic Heterocycles Containing a [6-6-5] or [7-6-5] Tricyclic Core Skeleton from a 2-Isocyanophenyl Propargylic Ester. Angew. Chem. Int. Ed. 2025, 64, e202414726.

2024

8.       Lu, D.; Lu, S.; Ding C.-H.; Li, X. Y.*; Xu, B.* Synthesis of β‑Carbonyl α‑Iminoamides by Double Insertion of Isocyanides into Aldehydes. Org. Lett. 2024, 26, 6335−6340.

7.       Zhuang, D.; Cheng, L.; Yan, Y.; Tang, Y.; Wang, Z.; Gu, J.; Lu, Y.; Li, X. Y.*; Li, Z. Y.* Three-component formal metathesis via remote activating strategy enabled (RASE) domino activation of two C(sp3)–O bonds in alkyl ethers. Org. Chem. Front. 2024, 11, 4138–4148.

6.       Wu, L.;Huang, Z. Y.*; Miao, J.; Wang, S.; Li, X. Y.*; Li, N.; Cao, X.; Yang, C. L.* Orienting Group Directed Cascade Borylation for Efficient One-Shot Synthesis of 1,4-BN-Doped Polycyclic Aromatic Hydrocarbons as Narrowband Organic Emitters.Angew. Chem. Int. Ed. 2024, 63, e202402020.

5.       Li, Y.; Li, X. Y.* Theoretical insights into the enantiodivergence induced by chiral phosphoric acid catalysis with a Lewis acid for the synthesis of N–N axially chiral atropisomers. Org. Biomol. Chem. 2024, 22, 1654–1661.

4.       Deng, Y.; Yang, Z.; Li, Y.; Li, X. Y.*; Xu, B.* Copper nitrate-enabled ring expansion reaction of cyclopropanes: a direct approach to 3-cyano-isoxazoline N-oxides. Org. Chem. Front. 2024, 11, 1404–1411.

3.       Zhang, K.; Huang, Q.; Yang, C.; Li, X. Y.* Theoretical Insights into the Regiodivergence in Ni-Catalyzed [2+2+2] Cycloaddition of Unsymmetric Diynes and CO2. Inorganics 2024, 12, 39.

2.       Huang, Q.; Li, Y.; Yang, C.; Wu, W.; Hai, J.; Li, X. Y.*  Atroposelective synthesis of N–N axially chiral pyrrolyl(aza)-quinolinone by de novo ring formation. Org. Chem. Front. 2024, 11, 726–734.

2023

1.       Yang, C.; Li, Y.; Huang, Q.; Li, X. Y.* Lewis Acid Catalyzed [4+1] Cycloaddition of o-Quinone Methides and Isocyanides: Mild and Efficient Synthesis of 3-Aryl-2-amino benzofurans. Synlett 2023, 34, 1230–1234.


Before SHU

1.       Li, X. Y.; Großkopf, J.; Jandl, C.; Bach, T. Enantioselective Visible Light-mediated Aza-Paternò-Büchi Reactions of Quinoxalinones. Angew. Chem. Int. Ed. 2021, 60, 2684–2688.

    2.       Li, X. Y.; Kutta, R. J.; Jandl, C.; Bauer, A.; Nuernberger, P.; Bach, T. Photochemically Induced Ring Opening of Spirocyclopropyl Oxindoles: Evidence for a Triplet 1,3-Diradical Intermediate and Deracemization by a Chiral Sensitizer. Angew. Chem. Int. Ed. 2020, 59, 21640–21647. (Hot Paper)

    3.       Pan, J.;† Li, X. Y.;† Lin, F.; Liu, J.; Jiao, N. Chemoselective Nitrosylation of Anilines and Alkynes via Fragmentary or Complete NO Incorporation. Chem. 2018, 4, 1427–1442. (†共同一作, 负责理论计算)

    4.       Liang, Y.-F.;† Li, X. Y.;† Wang, X. Y.; Zou, M. C.; Tang, C. H.; Liang, Y. J.; Song, S.; Jiao, N. Conversion of Simple Cyclohexanones into Catechols. J. Am. Chem. Soc. 2016, 138, 12271−12277. (†共同一作, 负责理论计算)

    5.       Li, X. Y.; Li, X. W.; Jiao, N. Rh-Catalyzed Construction of Quinolin-2(1H)-ones via C−H Bond Activation of Simple Anilines with CO and Alkynes. J. Am. Chem. Soc. 2015, 137, 9246−9249.

    6.       Sun, X.;† Li, X. Y.;† Song, S.; Zhu, Y. C.; Liang, Y. F.; Jiao, N. Mn-Catalyzed Highly Efficient Aerobic Oxidative Hydroxyazidation of Olefins: A Direct Approach to β-Azido Alcohols. J. Am. Chem. Soc. 2015, 137, 6059−6066. (†共同一作, 负责理论计算)

    7.       Chen, F.;† Huang, X. Q.;† Li, X. Y.;† Shen, T.; Zou, M. C.; Jiao, N. Dehydrogenative N-Incorporation: A Direct Approach to Quinoxaline N-Oxides under Mild Conditions. Angew. Chem. Int. Ed. 2014, 53, 10495–10499. (†共同一作, 负责理论计算)

    8.       Wen, X. J.;† Li, X. Y.;† Luo, X.; Wang, W. J.; Song, S.; Jiao, N. Intramolecular Csp -H/C-C Bond Amination of Alkyl Azides for the Selective Synthesis of Cyclic Imines and Tertiary Amines. Chem. Sci. 2020, 11, 4482−4487. (†共同一作, 负责理论计算)

    9.       Li, X. Y.; Pan, J.; Wu, H.; Jiao, N. Rh-catalyzed Aerobic Oxidative Cyclization of Anilines, Alkynes, and CO. Chem. Sci. 2017, 8, 6266−6273.

    10.     Li, X. Y.; Pan, J.; Song, S.; Jiao, N. Pd-catalyzed Dehydrogenative Annulation Approach for the Efficient Synthesis of Phenanthridinones. Chem. Sci. 2016, 7, 5384−5389 (ISACS19: Challenges in Organic Chemistry).

    11.     Li, X. Y.; Jandl, C.; Bach, T. Visible-Light-Mediated Enantioselective Photoreactions of 3‑Alkylquinolones with 4‑O‑Tethered Alkenes and Allenes. Org. Lett. 2020, 22, 3618−3622.

    12.     Li, X. Y.; Jandl, C.; Bach, T. Synthesis of Azocane- and Oxocane-annulated Furans by a [2+2] Photo­cycloaddition-Ring Opening Cascade. Synthesis 2021, 53, 723−730.

    13.     Li, X. Y.; Jiao, N. Reoxidation of Transition-metal Catalysts with O2. Chin. J. Chem. 2017, 35, 1349–1365.

    14.     Li, X. Y.;† Jin, X.;† Xu, J. X. Annuloselectivity in Reactions of Diacyl Dichlorides and Imines: Combined Experimental and Theoretical Studies. J. Org. Chem. 2015, 80, 6976−6985. (†共同一作)

    15.     Hou, S.;† Li, X. Y.;† Xu, J. X. N[1,3]-sigmatropic Shift in the Benzidine Rearrangement: Experimental and Theoretical Investigation. Org. Biomol. Chem. 2014, 12, 4952−4963. (†共同一作)

    16.     Li, X. Y.; Xu, J. X. DFT and Experimental Exploration of Intramolecular [2+2+2] Cycloaddition of Oxanorbornadienedicarboxylates and Analogues. J. Org. Chem. 2013, 78, 3039−3047.

    17.     Li, X. Y.; Xu, J. X. Annuloselectivity in Cycloadditions of Ketenes with Imines: A DFT Study. J. Org. Chem. 2013, 78, 347−355.

    18.     Li, X. Y.; Yang, Z. Y.; Xu, J. X. Comprehensive Theoretical Investigation on the Regioselectivity in the Nucleophilic Ring Opening of Epoxides. Curr. Org. Synth. 2013, 10, 169–177.

    19.     Li, X. Y.; Xu, J. X. Theoretical insights into the [4+2]/retro [4+2] cycloaddition approach to the synthesis of biaryls and polycyclic aromatics. Sci. China Chem. 2013, 56, 633–640.

    20.     Li, X. Y.; Xu, J. X. Theoretical Insights into the Metal-free and Formal [2+2+2] Cycloaddition Strategy via Intramolecular Cascade Propargylic ene/Diels–Alder Reactions with Tautomerization. Org. Biomol. Chem. 2011, 9, 5997–6003.

    21.     Qi, H. Z.;† Li, X. Y.;† Xu, J. X. Stereoselective Control in the Staudinger Reactions Involving Monosubstituted Ketenes with Electron Acceptor Substituents: Experimental Investigation and Theoretical Rationalization. Org. Biomol. Chem. 2011, 9, 2702–2714. (†共同一作)

    22.     Li, X. Y.; Xu, J. X. Theoretical Calculational Investigation on the Regioselectivity of the Ring Opening of Thiiranes with Ammonia and Amines.Tetrahedron 2011, 67, 1681–1688.

    23.     Li, X. Y.; Xu, J. X. Abundant Intramolecular Ring Rearrangements of 1-(N-Benzyloxycarbonylamino)-arylmethylphosphonate Phenyl monoesters Under Electrospray Ionization Conditions. Phosphorus, Sulfur, and Silicon, 2011, 186, 503–510.

    24.     Li, X. Y.; Chen, N.; Xu, J. X. An Improved and Mild Wenker Synthesis of Aziridines. Synthesis 2010, 20, 3423–3428.

    25.     Wang, W.; Li, X. Y.; Yang, X.; Ai, L.; Gong, Z.; Jiao, N.; Song S. Oxoammonium salts are catalysing efficient and selective halogenation of olefins, alkynes and aromatics. Nat. Commun. 2021, 12, 3873

    26.     Song S.; Li, X. Y.; Wei, J.; Wang, W.; Zhang, Y.; Ai, L.; Zhu, Y.; Shi, X.; Zhang, X.; Jiao, N. DMSO-catalysed late-stage chlorination of (hetero)arenes. Nat. Catal. 2020, 3, 107–115.

    27.     Huang, X.; Li, X. Y.; Xie, X.; Harms, K.; Riedel, R.; Meggers, E. Catalytic asymmetric synthesis of a nitrogen heterocycle through stereocontrolled direct photoreaction from electronically excited state. Nat. Commun. 2017, 8, 2245.

    28.     Huang, X. Q.; Li, X. Y.; Zou, M. C.; Song, S.; Tang, C. H.; Yuan, Y. Z.; Jiao, N. From Ketones to Esters by a Cu-Catalyzed Highly Selective C(CO)-C(alkyl) Bond Cleavage: Aerobic Oxidation and Oxygenation with Air. J. Am. Chem. Soc. 2014, 136, 14858–14865.

    29.     Li, X. W.; Lin, F.; Huang, K.; Wei, J.; Li, X. Y.; Wang, X.; Geng, X.; Jiao, N. Selective α-Oxyamination and Hydroxylation of Aliphatic Amides. Angew. Chem. Int. Ed. 2017, 56, 12307-12311.

    30.     Liu, J. Z.;† Wen, X. J.;† Qin, C.;† Li, X. Y.; Luo, X.; Sun, A.; Zhu, B.; Song, S.; Jiao, N. Oxygenation of Simple Olefins via Selective Allylic C-C Bond Cleavage: A Direct Approach to Cinnamyl Aldehydes, Angew. Chem. Int. Ed. 2017, 56. 11940-11944.

    31.     Huang, X. Q.; Li, X. Y.; Jiao, N. Copper-catalyzed Direct Transformation of Simple Alkynes to Alkenyl Nitriles via Aerobic Oxidative N incorporation. Chem. Sci. 2015, 6, 6355–6360.

    32.     Liang, Y. F.; Li, X. Y.; Wang, X. Y.; Yan, Y. P.; Feng, P.; Jiao, N. Aerobic Oxidation of PdII to PdIV by Active Radical Reactants: Direct C−H Nitration and Acylation of Arenes via Oxygenation Process with Molecular Oxygen. ACS Catal. 2015, 5, 1956−1963.

    33.     Wu, H.; Li, X. Y.; Yan, Z.; Ma, N.; Song, S.; Zhang, G.; Jiao. N. Cu(I)-Catalyzed [2+2+1] Cycloaddition of Amines, Alkynes and Ketenes: An Umpolung and Regioselective Approach to Full-Substituted β-Pyrrolinones. Org. Lett. 2021, 23, 762−766.

    34.     Pan, J.; Li, X. Y.; Qiu, X.; Luo, X.; Jiao, N. Copper-Catalyzed Oxygenation Approach to Oxazoles from Amines, Alkynes, and Molecular Oxygen. Org. Lett. 2018, 20, 2762–2765.

    35.     Zhu, Y. C.; Li, X. Y.; Wang, X.; Huang, X.; Shen, T.; Zhang, Y.; Sun, X.; Song, S.; Jiao, N. Silver-Catalyzed Decarboxylative Azidation of Aliphatic Carboxylic Acids. Org. Lett. 2015, 17, 4702−4705.

    36.     Feng, Peng.; Sun, X.; Su, Y.; Li, X. Y.; Zhang, L.−H.; Shi, X. D.; Jiao, N. Ceric Ammonium Nitrate (CAN) Catalyzed Modification of Ketones via Two C–C Bond Cleavages with the Retention of the Oxo-Group. Org. Lett. 2014, 16, 3388–3391.