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(1) Nanomaterial-based combination cancer therapies and their underlying mechanisms, including chemotherapy, photodynamic therapy, radiotherapy, gene therapy, and immunotherapy; (2) High-performance composite nanomaterials for biomedical imaging; (3) Mechanisms and strategies of efficient synergistic antibacterial therapy based on photodynamic and photo-responsive nanomaterials; (4) Tissue regeneration models and mechanisms based on complex bioactive substances.