Professor Wang Xuemei, winner of the National Outstanding Young Scholars Fund and China Young Women Scientists Award. In recent years, he has carried out research in nanomedicine and biomedical sensor imaging and precision diagnosis and treatment. He is the first in the world to discover and propose new technologies and methods of real-time dynamic targeting labeling and precision diagnosis and treatment of tumor and other major diseases based on in situ biosynthesis fluorescent and magnetic nanocluster probes of living tumor and other diseased cells/tissues. Based on this, an ultra-sensitive and ultra-fast intelligent probe and detection system has been designed and constructed to identify and detect novel coronavirus infection, cancer and other related pathological cells and their drug resistance. It has established new methods and instrument systems for accurate tracing of the lesions of novel coronavirus infection, cancer, Alzheimer's disease (AD) and other neurodegenerative diseases, arthritis, stroke and other diseases, as well as intelligent in vivo real-time dynamic cross-scale imaging and low-cost rapid diagnosis and detection, and proposed new non-invasive molecular diagnosis and treatment technologies with fully independent intellectual property rights. A new strategy of early detection, dynamic real-time monitoring, intervention and multi-mode precision diagnosis and treatment of relevant lesion sites in vivo has been realized. At the same time, in situ biosynthesis of intelligent diagnosis and treatment probes with optical, electrical, photoacoustic and magnetic properties using focal tissues, cells and exosomes such as living tumors has achieved real-time dynamic tracing, early detection and precise targeted diagnosis and treatment of multi-dimensional and multi-scale tumors and other small lesions. Related research results have been published in PNAS, Chem, Angew Chem and other international important core journals more than 200 papers, has been authorized by the United States patent, more than 40 national invention patents.