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成果及论文


第一和通讯作者论文:

1. Ran W#, Yang J#, Yu S#, Hu Q#, He Y#, Wang S. Wei C, Sun J, Zhu A, Li F, Zhang L, Li P, Hu H, Pan R, Yu Y, Yuan Y, Sun L, Wang Y, Zhang Z, Chen Z, Liu D, Yan Q, Wang D, Yu K, Wang Y, Zhuo J, Zhuang Z, Tao H, Zeng Q, Zhou K, Chen F, Tang W, Zhou Y, Bai R, Xu Y, Li N, Dai J, Zhao H, Park JE, Wang T, Ding Q*, Perlman S*, Zhao J*, Mao Y*, Wang S*, Zhao J*(2025). Interferon-stimulated gene GALNT2 restricts respiratory virus infections. Nature microbiology, 10.1038/s41564-025-02200-7.

2. Wang S#, Li W#, Wang L, Tiwari SK, Bray W, Wu L, Li N, Hui H, Clark AE, Zhang Q, Zhang L, Carlin AF, Rana TM(2025). Interferon-Inducible Guanylate-Binding Protein 5 Inhibits Replication of Multiple Viruses by Binding to the Oligosaccharyltransferase Complex and Inhibiting Glycoprotein Maturation. mBio 16:e02930-25.

3. Wang S#, Li W#, Hui H, Tiwari SK, Zhang Q, Croker BA, Rawlings S, Smith D, Carlin AF, Rana TM* (2020) Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and other coronaviruses by depleting membrane cholesterol. The EMBO J 39: e106057. (#co-first authors)

4. Wang L#, Wang S#, Wu L, Li W, Bray W, Clark AE, Gonzalez GM, Wang Y, Carlin AF, Rana TM* (2023) PCIF1-mediated deposition of 5'-cap N6, 2'-O-dimethyladenosine in ACE2 and TMPRSS2 mRNA regulates susceptibility to SARS-CoV-2 infection. Proceedings of the National Academy of Sciences 120 (5), e2210361120. (#co-first authors)

5. Wang S#, Zhang Q#, Tiwari SK#, Lichinchi G, Yau EH, Hui H, Li W, Furnari F, Rana TM* (2020) Integrin alphavbeta5 Internalizes Zika Virus during Neural Stem Cells Infection and Provides a Promising Target for Antiviral Therapy. Cell Reports 30: 969-983 e4. ( #co-first authors) (Highlighted by a Preview from Cell Stem Cell)

6. Zhang Q#Wang S#, Li W, Yau E, Hui H, Singh P, Achuthan V, Karris M, Engelman A, Rana TM* (2022). Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration. Nucleic Acids Research 50 (12), 6687-6701  (#co-first authors)

7. Zhang LJ#, Wang S#, Xia L, Lv C, Tang HW, Liang Z, Xiao G*, Pang DW* (2020) Lipid-Specific Labeling of Enveloped Viruses with Quantum Dots for Single-Virus Tracking. mBio 11(3). ( #co-first authors)

8. Wang S#, Zhang Q#, Hui H, Agrawal K, Karris MAY, Rana TM* (2020) An atlas of immune cell exhaustion in HIV-infected individuals revealed by single-cell transcriptomics. Emerging microbes & infections 9(1), 2333-2347.( #co-first authors)

9. Wang S#, Liu Y, Guo J, Wang P, Zhang L, Xiao G, Wang W* (2017) Screening of FDA-approved drugs for inhibitors of Japanese encephalitis virus infection. Journal of Virology 91(21):e01055-17. (Faculty 1000 Recommendation)

10. Wang S#, Liu H, Zu X, Liu Y, Chen L, Zhu X, Zhang L, Zhou Z, Xiao G*, Wang W* (2016) The ubiquitin-proteasome system is essential for the productive entry of Japanese encephalitis virus. Virology 498:116-127.

11. Yu S#, Hu H, Ai Q, Bai R, Ma K, Zhou M, Wang S* (2023) SARS-CoV-2 Spike-Mediated Entry and Its Regulation by Host Innate Immunity. Viruses 15(3), 6.


部分代表作成果:

呼吸道特异表达病毒受体ACE2和蛋白酶TMPRSS2的分子机制

Wang L*& Wang S* et al. PNAS, 2023


CH25H的广谱抗冠状病毒活性鉴定及其独特作用机制的研究

Wang S* & Li W * et al. EMBO J, 2020


寨卡病毒神经嗜性潜在受体的发现与应用

Wang S*, Zhang Q* & Tawari S* et al. Cell Reports, 2020

Vazquez et al. Cell Stem Cell, 2020


系统筛选HIV-1的宿主限制因子及功能验证

Zhang Q* & Wang S* et al. Nucleic Acids Research, 2022