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成果及论文


2025年

44. Q. Liu, X. R. Chen, K. N. Wang, Y. F. Wu, X. C. Zou,* Y. Li, Aggregation-Induced Emission Luminogens (AIEgens) in In Vitro Diagnostics: Advancing Biomarker Detection in Body Fluids. Interdisciplinary Medicine 2025, 6936170. 

43. C. Z. Zheng, L. W. Zhu, J. Y. Zhang, X. Deng, Z. Y. Zhong, X. He, Q. Y. Zhang, J. K. Liu, M. Miao, J. Lam, Y. Li,* M. Chen,* B. Z. Tang,* Acceptor motor-driven electronic donor-acceptor supramolecular scaffold towards imaging-guided tumor therapy. Chem. Sci. 2025, Accept 


42. T. Sun, W. B. Wu, S. L. Li, Y. Li,* Encyclopedia of Aggregation-induced Emission. Microbe Imaging and Killing. Spring Nature , 2025(书 稿)


41. J. Y. Song, G. Y. Chen, W. P. Zhu, Y. F. Wu,* S. C. Xu, K. N. Wang, Y. Z. Kong, L. Liang, H.-Q. Peng, J. F. Dong*, Z. Zhao*, Y. Li,*

 Stereoisomeric AIE Photosensitizers for Biofilm Inhibition and Host-directed Elimination of Intracellular Multidrug Resistant Bacteria. ACS Appl. Mater. Inter. 2025 5c04600.


40. L. W. Zhu, G. J. Song, W. T. Zhang, Y. F. Wu, Y. L. Chen, J. Y. Song, D. L. Wang, G. X. Li* B. Z. Tang*, Y. Li,Aggregation Induced Emission Luminogen  Bacteria Hybrid Bionic Robot for Multimodal Phototheranostics and Immunotherapy. Nat. Commun. 2025, 16, 2578.  (Nature Press)


39.  S. Q. Huang, Z. Y. Wang, Q. Wu, B. Wu, B. B. Chen, Y. Li,* Z. J. Qiu,* Z. Zhao,* B. Z. Tang,* Top-Down Assembly of Photosensitizable Flexible Wood Dressing: Synergistic Anti-Infection and Moisture Management to Accelerate Wound Healing. Adv. Funct. Mater. 2025202423123. 

https://doi.org/10.1002/adfm.202423123


38. X. R. Chen, Q. Liu, J. J. Zhang,* L. J. Tan, J. G. Li, M.-L. Ke,* B. Z. Tang,* Y. Li,* Fully Inter-Restricted Assembly of Aggregation-Induced Emission Luminogens and Polymer Enables Ultra-Bright Nanoparticles for Sensitive Point-Of-Care Diagnosis. ACS Nano 2025, 15372.


37. Q. Liu, X. R. Chen, J. G. Li, L. J. Tan, K. N. Wang, J. M. Zhang, H. M. Dong *, Y. Li,* B. Z. Tang,* AIE Nanoparticle with Enhanced Fluorescence for Ultrasensitive Lateral Flow Immunoassays and Point-of-Care Diagnosis of Interstitial Lung Disease. Biosens. Bioelectron. 2025, 117068. 

  


36. M. Adhikari,# B. M. Bakadia,# L. Wang, Y. Li, Z. J. Shi,* G. Yang,* Electricallymodified bacterial cellulose tailored with plant based green  materials for infected wound healing applications. Biomaterials Advances 2025, 167, 214087.


2024 年

35. X. R. Chen, K. N. Wang, Q. Liu, L. J. Tan, Y. Li,* B. Z. Tang,* Highly luminescent AIE nanoparticle-equipped sensitive point-of-care  testing of neuron-specific enolase for small cell lung cancer diagnosis. Sensors Actuat. B-Chem, 2024, 137201.

https://www.sciencedirect.com/science/article/pii/S0925400524019312?via%3Dihub


34. B. M. BakadiaZ. J. Shi,Y. Li,* G. Yang,*  Nanocellulose Composities in Skin Tissue Engineering and Wound Dressings. Biomaterials Science Series, 2024. Royal Society of Chemistry (书 稿)

https://doi.org/10.1039/9781837673094-00267       


33. M. L. Zhi,# T. Sun,# D. L. Wang, Q. Y. Zeng, Y. Li, X. Su,* X. Feng,* B. Z. Tang,* Manipulation of benzoquinolizinium-based regioisomeric AIE-active photosensitizers for effective multidrug-resistant bacterial eradication. Mater. Chem. Front. 202410.1039/d4qm00908h.


32. S. Q. Huang, Z. Y. Wang, X. M. Lu, J. Y. Gong, L. P. Cheng, J. X. Wang, J. Q. Zhang, P. Alam, Z. Q. Lv, H. F. Zhang,* Y. Li,* Z. J. Qiu,* Z. Zhao,* B. Z. Tang,* Interception and in Situ Eradication of  Airbone Pathogens by Ecofriendly, Biodegradable Wooden Filters. ACS Materials Lett. 2024, 6,4379-4387.

https://pubs.acs.org/doi/10.1021/acsmaterialslett.4c01294


31. X. Y. Liu, Y. Chen, C. Hang, J. X. Cheng, D. L. Peng, Y. Li,* X. Y. Jiang,* Coupling Nanoscale Precision with Multiscale Imaging: A Multifunctional Near-infrared Dye for the Brain. ACS Nano 2024, 22233-22244.

https://pubs.acs.org/doi/10.1021/acsnano.4c06103


30. S. L. Peng,# J. Y. Song,# S. T. Wu, Q. Wang, L. Y. Shen, D. M. Li, J. Peng, Q. L. Zhang,* X. J. Yang,* H. Xu, C. Redshaw, Y. Li,* Aggregation-induced emission photosensitizer with Ag(I)-π interaction-enhanced reactive oxygen species for eliminating multi-drug resistant bacteria. ACS Appl. Mater. Inter.2024, 4c05202.

https://pubs.acs.org/doi/10.1021/acsami.4c05202


29.  L. W. Zhu, Y. M. Wang, J. Y. Song, Z. H. Sheng,* J. Qi, Y. Li,* G. X. Li,* B. Z. Tang,* Two-Photon Absorption Aggregation-Induced Emission Luminogen/Paclitaxel Nanoparticles for Cancer Theranostics. ACS Appl. Mater. Inter.20244c02442. 

 https://doi.org/10.1021/acsami.4c02442 


28. B. Z. He,# Y. Li,# M Li, M. M. Kang, X. Y. Liu, J. C. Huang,* D. Wang,* J. W. Y. Lam,* B. Z. Tang,*  Pyridinium-Yne Click Polymerization: A Facile Strategy toward Functional Poly(Vinylpyridinium Salt)s with Multidrug-Resistant Bacteria Killing Ability. Angew. Chem. Int. Edit.2024, 202405030      

 https://onlinelibrary.wiley.com/doi/10.1002/anie.202405030


27. Y. F. Wu,  J. G. Li,  L. W. Zhu, D. L. Wang, J. Y. Song, X. Y. Yu, Y. Li,* B. Z. Tang,* Photosensitive AIEgens sensitize bacteria to oxidative damage and modulate the inflammatory responses of macrophages to salvage the photodynamic therapy against MRSA. Biomaterials 2024, 309,122583.

https://doi.org/10.1016/j.biomaterials.2024.122583


26. B. M. Bakadia, R. Z. Zheng, A. A. Q. Ahmed, Z. J. Shi, B. L. Babidi, T. Sun, Y. Li,* G. Yang,* Teicoplanin-decorated Reduced Graphene Oxide Incorporated Silk Protein Hybrid Hydrogel for Accelerating Infectious Diabetic Wound Healing and Preventing Diabetic Foot Osteomyelitis. Adv. Healthc. Mater. 2024202304572.

https://doi.org/10.1002/adhm.202304572


25. M. Chen,# R. H. Dong,# J. Y. Song, J. Qi, J. J. Zhang, Z. Zhao,* W. T. Zhang, Y. Li,* B. Z. Tang,* Fast and Stable Antibacterial Coating of Photosensitive Aggregation-induced Emission Luminogens for Disinfection on Medical Devices. Adv. Healthc. Mater. 2024, 2303967.

https://onlinelibrary.wiley.com/doi/10.1002/adhm.202303967


2023 年

24.Y. F. Wu,# X. H. Chen,# L. W. Zhu, D. L. Wang, X. Li, J. Y. Song, D. Wang,* X. Y. Yu, Y. Li,* Ben Zhong Tang,*An endoplasmic reticulum-targeted type-I aggregation-induced emission luminogen for synergetic tumor ablation with glibenclamide. ACS Appl. Mater. Inter. 2023 15, 50821-50835. 


23. Q. Wang, X. Feng, H. Xu, G. Guo, Y. Li,* Q. L. Zhang, *Recent progess of antibacterial hydrogel materials for biomedical applications. J. Mater. Chem.  C  2023,  11, 12848


22. H. R. Wang, Q. Y. Li, Y. Li,* B. Z. Tang,* et al. Aggregation-Induced Emission (AIE), Life and Health. ACS Nano 202317, 14347-14405. 


21. Z. P. Shen, W. Zhu, Y. J. Huang, J. J. Zhang, Y. F. Wu, Y. Z. Pan, G. Yang, D. Wang,* Y. Li,* B. Z. Tang,* Visual Multifunctional Aggregation-induced emission Based Bacterial Cellulose for Killing of Multidrug-resistant Bacteria. Adv. Healthc. Mater. 20232300045. 


20. Y. S. Lin, M. M. Yi, X. L. Guan, S. Chen, L. Y. Yang, S. P. Li,* Y. Li,* L. M. Zhang,* “Two birds with one stone” strategy for the lung cancer therapy with bioinspired AIE aggregates. J. Nanobiotechnol. 202321, 49. 


2022 年

19. W.-J. Wu, T. K. Peng, W. P. Zhu, S. X. Ma, G. Wang, Y. Li,* B. Liu, H.-Q. Peng,* Visualization of Supramolecular Assembly by Aggregation-Induced  Emissionm. Aggregate. 2022, e297. 


18. Y. F. Wu, J. G. Li, Z. P. Shen, D. L. Wang, R. H. Dong, J. J. Zhang, Y. Z. Pan, Y. Li, * D. Wang, * B. Z. Tang, * Double‐pronged Antimicrobial Agents based on a Donor‐π‐Acceptor Type Aggregation‐Induced Emission Luminogen. Angew. Chem. Int. Edit. 2022, 202212386. 


17. J. Y. Gong, P. F. Wei, J. K. Liu, Z. Zhao, W. J. Zhao, C. Ma, J. W. Y. Lam, K. S. Wong, Y. Li,* B. Z. Tang* Polarity-triggered anti-Kasha syatem for high-contrast cell imaging and classification. Aggregate. 2022, e265. 


16. X. H. Wang, M. R. Song, Y. W. Liu, X. Feng,* D. Wang, C. Redshaw, K. Zhu, Y. Li,* B. Z. Tang,* Lipid Droplet-specific Red Aggregation-induced Emission  Luminogens: Fast Light-up of Gram-positive pathogens for Identification of Bacteria. ACS Materials Lett. 20224, 1523-1530.


15. P. H. Xiao, Z. P. Shen, D. L. Wang, Y. Z. Pan, Y. Li,* , J. Y. Gong, L. Wang, D. Wang,* B. Z. Tang*  Precise Molecular Engineering of Type I Photosensitizers with Near-Infrared Aggregation-Induced Emission for Image-Guided Photodynamic Killing of Multidrug-Resistant BacteriaAdv. Sci. 20229, 2104079. 


14. W. P. Zhu,# Y. Li,# S. X. Guo, W. J. Guo, T. K. Peng, H. Li, B. Liu, H. Q. Peng,* B. Z. Tang* Stereoisomeric Engineering of Aggregation-Induced Emission Photosensitizers towards Fungal Killing. Nat. Commun. 2022, 13, 7046.  (Nature Press)


13. J. J. Zhang,# Y. Li,# F. L. Chai,# Q. Z. Li, D. Wang, L. P. Liu,* B. Z. Tang,* X. Y. Jiang* Ultrasensitive Point of-Care Biochemical Sensor Based on Metal AIEgen Frameworks. Sci. Adv. 20228, eabo1874. (Science Press)


12. R. H. Dong,# Y. Li,# M. Chen, P. H. Xiao, Y. F. Wu, K. Zhou, Z. Zhao,* B. Z. Tang* In Situ Electrospinning of Aggregation-Induced Emission Nanofibrous Dressing for Wound Healing. Small Methods 20226, 2101247.


2018-2021 年

11. H. X. Li, W. Zhu, M. Li, Y. Li,* R. T. K. Kwok, J. W. Y. Lam, L. Wang, D. Wang,* B. Z. Tang* Side Area-Assisted 3D Evaporator with Antibiofouling Function for Ultra-Efficient Solar Steam Generation. Adv. Mater. 2021, 2102258. 


10. Q. Wu, Y. M. Li, Y. Li,* D. Wang,* B. Z. Tang* Hydrogen peroxide-responsive AIE probe for imaging-guided organelle targeting and photodynamic cancer cell ablation. Mater. Chem. Front. 2021, 5, 3489-3496. 


9. M. Li, H. Li, Q. Wu, N. Niu, J. C. Huang, L. M. Zhang, Y. Li,* D. Wang,* B. Z. Tang* Hypoxia-activated Probe for NIR Fluorescence and Photoacoustic Dual-mode Tumor Imaging. iScience 202124, 102261.   


8. X.-M. Cai,# Y. T. Lin,# Y. Li,# X. F. Chen, Z. Y. Wang, X. Q. Zhao, S. L. Huang,* Z. Zhao,* B. Z. Tang* BioAIEgens Derived from Rosin: How Does Molecular Motion Affect Their Photophysical Processes in Solid State? Nat. Commun. 202112, 1773. (Nature Press)


7. Y. Li,F. Liu,# J. J. Zhang, X. Y. Liu, P. H. Xiao, H. T. Bai, S. Chen, D. Wang, S. H. P. Sung, R. T. K. Kwok, J. Z. Shen, K. Zhu,* B. Z. Tang* Efficient Killing of  Multidrug-Resistant Internalized Bacteria by AIEgens in Vivo. Adv. Sci. 2021, 2001750.

 


6. Y. Li,#  R.B. Tang,# X.Y. Liu, J.Y. Gong, Z. J. Zhao, Z. H. Sheng, J. J. Zhang, X. Y. Li, G. L. Niu, R. T. K. Kwok, W. F. Zheng,* X.Y. Jiang,* B. Z. Tang* Bright  Aggregation-Induced Emission Nanoparticles for Two-Photon Imaging and Localized Compound Therapy of Cancers. ACS Nano 202014, 16840-16853.


5. Z. Hu,# Y. Li,# M. M. Kang, M. M. Islam, M. S. Chen, J. Zhang, Y. Xiao, X. Feng,* C. Redshaw, M. L. Zhang,* Q. Chen, S. Xie* J. W. Y. Lam, B. Z. Tang* Aggregation-Induced Emission Luminogen: A New Perspective in the Photo-Degradation of Organic Pollutants. EcoMat 2020, 2, e12024.


4. X. J. Shi, S. H. P. Sung, J. H. C. Chau, Y. Li,* Z. Y. Liu, R. T. K. Kwok,* J. K. Liu, P. H. Xiao, J. J. Zhang, B. Liu, J. W. Y. Lam, B. Z. Tang* Killing G (+) or G (−) Bacteria? The Important Role of Molecular Charge in AIE-Active Photosensitizers. Small Methods 2020, 2000046.


3. Q. Y. Li, # Y. Li,# T. L. Min,# J. Y. Gong, L. L. Du, K. Li, D. L. Phillips, J. K. Liu, J. W. Y. Lam, H. H. Y. Sung, I. D. Williams, R. T. K. Kwok, J. G. Wang,* B. Z. Tang* Time-dependent Photodynamic Therapy for Multiple Targets: A Highly Efficient AIE-active Photosensitizer for Selective Bacterial Elimination and Cancer Cell Ablation. Angew. Chem. Int. Edit. 2019, 59, 9470-9477.


2. X. Feng,# Y. Li, # X. W. He, H. X. Liu, Z. Zhao, R. T. K. Kwok, M. R. J. Elsrgood, J. W. Y. Lam, B. Z. Tang* A Substitution-dependent Light-up fluprescence probe for   selectively detecting Fe3+ ions and its cell imaging application. Adv. Funct. Mater. 2018, 201802833.


1. Y. Li,# Z. Zhao,# J. J. Zhang, R. T. K. Kwok, S. Xie, R. B. Tang, Y. X. Jia, J. C. Yang, L. Wang, J. W. Y. Lam, W. F. Zheng,* X. Y. Jiang,* B. Z. Tang* Bifunctional  Aggregation-induced Emission Luminogen for Monitoring and Killing of Multidrug-resistant Bacteria. Adv. Funct. Mater. 2018, 201804632.