1. Tu B*, Song K*, Zhou ZY*, Lin LC, Liu ZY, Sun H, Zhou Y, Sha JM, Shi Y, Yang JJ#, Zhang Y#, Zhao JY#, Tao H#. SLC31A1 loss depletes mitochondrial copper and promotes cardiac fibrosis. Eur Heart J. 2025 Mar 6:ehaf130. doi: 10.1093/eurheartj/ehaf130IF: 37.6 Q1 . Epub ahead of print. PMID: 40048660. (IF: 37.6)
2. Wang J, … Wang F#, Gui YH#, Tao H#, Zhao JY#. NOTCH1 mitochondria localization during heart development promotes mitochondrial metabolism and the endothelial-to-mesenchymal transition in mice. Nature Communications 2024; 15(1):9945. doi: 10.1038/s41467-024-54407-7. (IF: 17.69) 作为Featured article入选From molecules and cells to organisms精选集
3. Cai K, … Gui YH#, Shi Y#, Zhao JY#. Maternal folic acid over-supplementation impairs cardiac function in mice offspring by inhibiting SOD1 expression. Cardiovascular Research 2024;120(16):2092-2103. doi: 10.1093/cvr/cvae203. (IF: 13.08) 封面论文、Editor’s Choice
4. Ding JF, … Yang JJ#, Zhao JY#, Tao H#. Epitranscriptomic regulation of cardiac fibrosis via YTHDF1-dependent PIEZO2 mRNA m6A modification Cardiovascular Research 2024; Nov 5:cvae239. (IF: 13.08) Cardiovas Res同期Invited editorial专文评述
5. Zhou ZY, … Tao H#, Zhao JY#. Branched-chain amino acids deficiency promotes diabetic cardiomyopathy by activating autophagy of cardiac fibroblasts. Theranostics 2024;14(19):7333-7348. (IF: 12.4)
6. Zhou ZY, … Pan ZQ#, Cao J#, Lin FQ#, Zhao JY#. Branched-Chain Amino Acids Deficiency Promotes Diabetic Neuropathic Pain Through Upregulating LAT1 and Inhibiting Kv1.2 Channel. Advanced Science 2024;e2402086. (IF: 17.52)
7. Shi JW, … Zhao JY#, Li MQ#. TNFSF14+ natural killer cells prevent spontaneous abortion by restricting leucine-mediated decidual stromal cell senescence. The EMBO Journal 2024;doi: 10.1038/s44318-024-00220-3. (IF: 9.4)
8. Liu ZY, … Yang JJ#, Zhao JY#, Tao H#. N6-Methyladenosine-mediated phase separation suppresses NOTCH1 expression and promotes mitochondrial fission in diabetic cardiac fibrosis. Cardiovascular Diabetology 2024;23(1):347. doi: 10.1186/s12933-024-02444-3. (IF: 8.5)
9. Chen J, … Zhao JY#, Zhu T#, Sun L#, Fan G#. Lactylated Apolipoprotein C-II Induces Immunotherapy Resistance by Promoting Extracellular Lipolysis. Advanced Science 2024;e2406333. (IF: 17.52)
10. Xiang H, … Xu C#, Zhou Y#, Gu J#, Zhao JY#, Hou Y#, Ding C#. Proteogenomic insights into the biology and treatment of pan-melanoma. Cell Discovery 2024;10(1):78. doi: 10.1038/s41421-024-00688-7. (IF: 38.08)
11. Yin YN, …. Zhao R#, Sun K#, Ding C#, Zhao JY#. Proteome profiling of early gestational plasma reveals novel biomarkers of congenital heart disease. EMBO Molecular Medicine. 2023; e17745. (IF: 14.26) EMBO Mol Med同期News & Views专文评述
12. Zhao R*, … Zhou XY#, Cao J#, Sun K#, Zhao JY#. Gestational palmitic acid suppresses embryonic GATA-binding protein 4 signaling and causes congenital heart disease. Cell Reports Medicine 2023; 4(3):100953. (IF: 16.99)
13. Zhao R*, … Tao H#, Zhao SM#, Zhao JY#. Nuclear ATR lysine-tyrosylation protects against heart failure by activating DNA damage response. Cell Reports 2023; 42(4):112400. (IF: 9.99)
14. Tang L*, … Zhao JY#, Jin L#. Dysregulated Gln-Glu-α-ketoglutarate axis impairs maternal decidualization and increases the risk of recurrent spontaneous miscarriage. Cell Reports Medicine 2023; doi:10.1016/j.xcrm.2023.101026. (IF: 16.99)
15. Hu S*, … Zhao JY#, Xu W#, Zhao SM#. Amino acids downregulate SIRT4 to detoxify ammonia through the urea cycle. Nature Metabolism 2023;5(4):626-641. (IF: 19.74)
16. Wang Y*, … Zhang X#, Zhao JY#, Hou Y#, Ding C#. Proteogenomics of diffuse gliomas reveal molecular subtypes associated with specific therapeutic targets and immune-evasion mechanisms. Nature Communications 2023;14(1):505. (IF: 17.69)
17. Li L*, … Zhao JY#, Hou Y#, Ding C#. Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes. Nature Communications 2023;14(1):1751. (IF: 17.69)
18. Li L*, … Zhou P#, Zhao JY#, Hou Y#, Ding C#. Integrative proteogenomic characterization of early esophageal cancer. Nature Communications 2023;14(1):1666. (IF: 17.69)
19. Deng M*, … Xu C#, Shi G#, Ji Y#, Zhao JY#, Zhou J#, Fan J#, Hou Y#, Ding C#. Proteogenomic Characterization of Cholangiocarcinoma. Hepatology 2023.;77(2):411-429. (IF: 17.3)
20. Zhang X*, … Gui YH#, Zhao JY#. Gestational Leucylation Suppresses Embryonic T-Box Transcription Factor 5 Signal and Causes Congenital Heart Disease. Advanced Science. 2022; 9(15):e2201034. (IF: 17.52)
21. Cai K*, … Gui YH#, Zhao JY#. Nicotinamide Mononucleotide Alleviates Cardiomyopathy Phenotypes Caused by Short-Chain Enoyl-CoA Hydratase 1 Deficiency. JACC-Basic to Translational Science 2022;7(4):348-362. (IF: 9.53)
22. Zhou WJ*, … Zhao JY#, Jin LP#, Li MQ#. Fructose-1,6-bisphosphate prevents pregnancy loss by inducing decidual COX-2+ macrophage differentiation. Science Advances 2022;8(8):eabj2488. (IF: 14.96)
23. Li C*, … Zhao JY#, Wang H#. Master MicroRNA-222 Regulates Cardiac MicroRNA Maturation and Triggers Tetralogy of Fallot. Signal Transduction and Targeted Therapy 2022;7:165. (IF: 38.1)
24. Hu SH*, … Zhao JY#, Xu W#, Zhao SM#. Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake. Cell Reports 2022;38(11):110509. (IF: 9.99)
25. Li Y*, … Liu T#, Shen K#, Zhao JY#, Hou Y#, Ding C#. Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals new therapeutic strategies. Nature Communications 2022; 29;13(1):5723. (IF: 17.69)
26. Qu Y*, … Zhang H#, Zhao JY#, Ye D#, Ding C#. A Proteogenomic Analysis of Clear Cell Renal Cell Carcinoma in a Chinese Population. Nature Communications 2022;13(1):2052. (IF: 17.69)
27. Qu Y*, … Zhao JY#, Zhang H#, Ye D#, Ding C#. Proteogenomic characterization of MiT family translocation renal cell carcinoma. Nature Communications 2022;13(1):7494. (IF: 17.69)
28. Shen Y, … Zhao JY#, Cheng L#. Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α. Cell Death & Disease 2022;13(7):643. (IF: 9.69)
29. Zhang Y*, … Jin L#, Zhao JY#, Zhou X#. Acox2 is a regulator of lysine crotonylation that mediates hepatic metabolic homeostasis in mice. Cell Death & Disease 2022;13(3):279. (IF: 9.69)
30. Zhou Y*, … Zhang Y#, Zhao JY#, Tao H#. METTL3 boosts glycolysis and cardiac fibroblast proliferation by increasing AR methylation. International Journal of Biological Macromolecules 2022;223(A):899-915. (IF: 8.03)
31. Sun H*, … Zhao JY#, Zhang Y#, Tao H#. MTHFR epigenetic derepression protects against diabetes cardiac fibrosis. Free Radical Biology and Medicine 2022;193(1):330-341. (IF: 8.1)
32. Zhang X, … Zhao JY#. Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation. Cell Reports 2021;37(2):109821. (IF: 9.99)
33. Wang XH*, … Jin LP#, Zhao JY#. Low embryonic villous succinate accumulation increases recurrent spontaneous abortion risk. Nature Communications 2021;12(1):3428. (IF: 17.69)
34. Xu S, … Zhao JY#. Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis. Signal Transduction and Targeted Therapy 2021;6(1):54. (IF: 38.1)
35. Zhang Y*, … Zhao JY#, Zhou XY#. Two sides of NNMT in alcoholic and nonalcoholic fatty liver development. Journal of Hepatology 2021;74(5):1250-1253. (IF: 30.08)
36. Xu W*, … Zhao JY#, Zhang H#, Ye D#. Adenylate cyclase-activating polypeptide 1 gene methylation predicts prognosis and the immune microenvironment of bladder cancer. Clinical and Translational Medicine 2021;11:e597. (IF: 8.55)
37. Qu YY*, … Ye DW#, Zhao SM#, Zhao JY#. Inactivation of the AMPK-GATA3-ECHS1 Pathway Induces Fatty Acid Synthesis That Promotes Clear Cell Renal Cell Carcinoma Growth. Cancer Research 2020; 80(2):319-333. (IF: 13.31)
38. Mei X*, … Wang H#, Zhao JY#, Zhao S#, Xu W#. Inhibiting MARSs reduces hyperhomocysteinemia-associated neural tube and congenital heart defects. EMBO Molecular Medicine 2020; 12(3):e9469. (IF: 14.26)
39. Li Y*, … Zhao SM#, Zhao JY#. APC/CCDH1 synchronizes ribose-5-phosphate levels and DNA synthesis to cell cycle progression. Nature Communications 2019; 10(1):2502. (IF: 17.69)
40. Wang D*, … Zhao SM#, Zhao JY#. Colonic lysine homocysteinylation induced by high-fat diet suppresses DNA damage repair. Cell Reports 2018; 25:398-412. (IF: 9.99)
41. Wang D*, … Zhao SM#, Wang H#, Zhao JY#. Lower circulating folate induced by a Fidgetin intronic variant is associated with reduced congenital heart disease Susceptibility. Circulation 2017; 135(18):1733-1748. (IF: 39.92)
42. Xu S*, … Zhao JY#, Zhao SM#. Butyrate induces apoptosis by activating PDC and inhibiting complex I through SIRT3 inactivation. Signal Transduction and Targeted Therapy 2017; 2, e16035. (IF: 38.1)
43. Zhao JY*, Liang L*, Gu X*, …Tao YX#. DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons. Nature Communications 2017; 8:14712. (IF: 17.69)
44. Xu JT*, Zhao JY*, Zhao X*, … Tao YX#. Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesia. Journal of Clinical Investigation 2014; 124(2):592-603. (IF: 19.46)
45. Zhao JY*, Qiao B*, Duan WY*, … Huang GY#, Jin L#, Wang HY#. Genetic variants reducing MTR gene expression increase the risk of congenital heart disease in Han Chinese populations. European Heart Journal 2014; 35(11):733-42. (IF: 35.86)
46. Zhao X*, Tang Z*, Zhang H*, Atianjoh FE*, Zhao JY*, … Tao YX#. A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons. Nature Neuroscience 2013; 16(8):1024-31. (IF: 28.77)
47. Zhao JY*, Yang XY*, Shi KH*, … Wang HY#. A functional variant in the cystathionine β-synthase gene promoter significantly reduces congenital heart disease susceptibility in a Han Chinese population. Cell Research 2013, 23:242-253. (IF: 46.3)
48. Zhao JY*, Yang XY*, Gong XH*, … Qiao B#, Wang HY#. Functional variant in methionine synthase reductase intron-1 significantly increases the risk of congenital heart disease in the Han Chinese population. Circulation 2012; 125(3):482-90. (IF: 39.92)
