52.ControllableReductiveAlkylationofMonodentatePhosphine Ligandsunder IronCatalysis

Qingyun Wu, Shasha Geng, Adong Qiao, Siyu Wang, Jinping Yuan, Yun He, Zhang Feng*

https://doi.org/10.1021/jacs.5c12288

Controllable Reductive Alkylation of Monodentate Phosphine Ligands under Iron Catalysis | Journal of the American Chemical Society

51.Silyl Radical-Promoted Defluorination of Fluoroalkyl Ketones to Access Fluorinated 1,3-Dienes

Hong Huang,  Feihu Gou, Yu Pu, Jinping Yuan, Mei Bai, Jiang Zhu,* Suping Li, Zhang Feng*Qingyun WuShasha GengAdong QiaoSiyu WangJinping YuanYun HeZhang Feng*

Chin. J. Chem. 2025, 43, 2901—2908

https://onlinelibrary.wiley.com/doi/full/10.1002/cjoc.70175

50.Reductive Dicarbofunctionalization of Unactivated Internal Alkenes via Iron Catalysis

Haoran Hou, Siyu Wang, Hong Huang, Qingyun Wu, Shasha Geng, Biao Xu,* Zhang Feng*

Org. Lett. 2025, 27, 7200−7205

https://pubs.acs.org/doi/10.1021/acs.orglett.5c02134

49.Iron-Catalyzed Tunable Alkene Migratory Silylation and Transposition

Bohao Guo, Yu Pu, Ruichen Zhang, Hong Huang, Qingyun Wu, Shasha Geng*, Chang Qiao*, Zhang Feng*

Org. Lett. 2025, 27, 5181–5187

https://pubs.acs.org/doi/10.1021/acs.orglett.5c01273

48.Advances in dicarbofunctionalization of alkenes, alkynes and allenes via iron catalysis

Bohao Guo, Yu Pu, Siyu Wang, Feihu Gou, Hongli Ju, Xianrong Chen, Zhiqiang Liu and Zhang Feng*

Chem. Commun., 2025, Advance Article

https://pubs.rsc.org/en/content/articlelanding/2025/cc/d5cc02919h

47.Iron-Catalyzed Divergent Skeletal Editing of Benzofurans

Chaoqun Shi, Enhui Wang, Yuxuan Zhang,Tengyue Ma, Ruichen Zhang, Hong Huang,Yun He, Qian Peng*,and Zhang Feng*

CCS Chem. 2025.

https://www.chinesechemsoc.org/doi/10.31635/ccschem.025.202505855

46.lron-Catalyzed Reductive Deoxygenation of Nitroarenes to Access N-Heterocycles

Z Lin, R Zhang, H Huang, B Guo, P Xian, C Qiao, Z Feng*

Advanced Synthesis & Catalysis. 2025, 5, e202401531

https://advanced.onlinelibrary.wiley.com/doi/10.1002/adsc.202401531

45.Iron-Catalyzed Reductive Cross-Coupling of Heterocyclic Bromides

H Ju, S Wang, B Guo, Q Wu, C Zou, Y He, C Huang, Z Feng*

ACS Catalysis. 2025, 15, 7700–7709

https://pubs.acs.org/doi/10.1021/acscatal.5c01292

44. Advances in disilylation reactions to access cis/trans-1,2-disilylated and gem-disilylated alkenes

Shasha Geng, Yu Pu, Siyu Wang, Yanru Ji, Zhang Feng*

Chem. Commun., 2024, 60, 3484–3506

Advances in disilylation reactions to access cis/trans-1,2-disilylated and gem-disilylated alkenes - Chemical Communications (RSC Publishing)

43. Protocol for iron-catalyzed cross-electrophile coupling of aryl chlorides with unactivated alkyl chlorides

Pengjie Xian,* Hong Huang, Ruichen Zhang, Shasha Geng, and Zhang Feng*

STAR Protocols. 2024, 5, 102846

https://www.sciencedirect.com/science/article/pii/S266616672400011X?via%3Dihub

42. Iron-Catalyzed Regioselective Reductive Fluoroalkylalkenylation of Unactivated Alkenes

Siyu Wang, Bohao Guo, Tong Mu, Zhengli Liu, Yun He, Xiao-Song Xue, and Zhang Feng*

ACS Catal. 2024, 14, 1575–1583

https://doi.org/10.1021/acscatal.3c05690

41. Recent Progress in Transition-Metal-Catalyzed Reductive Cross-Coupling Reactions Using Diboron Reagents as Reductants

Shasha Geng,# Chaoqun Shi,# Bohao Guo, Haoran Hou, Zhengli Liu,* Zhang Feng*

ACS Catal. 2023, 13, 15469

https://pubs.acs.org/doi/10.1021/acscatal.3c04342

40. Substituent-Controlled Site-Selective Silylation of 2H-indazoles to Access Silylated 1H-indazoles and 2H-indazoles under Transition Metal Free Conditions

Jia Jia,# Shuai Chen,# Ting Mao, Jinlan Li, Weipiao Li, An-Jun Wang, Dezhi Yang, Zhengli Liu,* Chun-Yang He,* and Zhang Feng*

Org. Chem. Front. 2023, 10, 5389

https://pubs.rsc.org/en/Content/ArticleLanding/2023/QO/D3QO01103H

39. Catalytic cross-electrophile coupling of aryl chlorides with unactivated alkyl chlorides: The synergy of iron and Li

Yun Zhang, Ping Du, Yanru Ji, Siyu Wang, Yanqing Zhu, Zhengli Liu, Yun He, Qian Peng*, Zhang Feng*

Chem 2023, 9, 3623-3636

https://www.sciencedirect.com/science/article/pii/S2451929423004102

38. Thioethers as Dichotomous Electrophiles for Site-Selective Silylation via C-S Bond Cleavage

Shuai Chen#, Xueying Guo#, Haoran Hou, Shasha Geng, Zhengli Liu*, Yun He, XiaoSong Xue*, and Zhang Feng*

Angew. Chem. 2023, e202303470

https://onlinelibrary.wiley.com/doi/10.1002/anie.202303470              IF: 16.6 Q1

37. Iron/B2pin2 Catalytic System Enables the Generation of Alkyl Radicals from Inert Alkyl C-O Bonds for Amine Synthesis

Yanqing Zhu, Shuai Chen, Zhen Zhou, Yun He, Zhengli Liu,* Yang Liu,* and Zhang Feng*

Chin. Chem. Lett. 2023, 10.1016/j.cclet.2023.108303              IF: 9.1 Q1

https://www.sciencedirect.com/science/article/pii/S1001841723001651

36. Iron-Catalyzed Decarbonylative Borylation Enables the Diversification of (Hetero)Aryl and Alkyl Carboxylic Acids 

Qingru Wen,# Shuo Chen,# Chaoqun Shi, Shuai Chen, Yanru Ji, Jian Guo, Zhengli Liu, Yun He, and Zhang Feng*

Cell. Rep. Phys. Sci. 2022, 3, 100995

https://www.sciencedirect.com/science/article/pii/S2666386422002818

35. Iron-Catalyzed Cross-Electrophile Coupling of Inert C-O Bonds with Alkyl Bromides 

Shuo Chen,# Zijian Wang,# Shasha Geng, Hongdan Zhu, Zhengli Liu, Yun He, Qian Peng* and Zhang Feng*

CCS Chem. 2022, 10.31635/ccschem.022.202202234              IF: 11.2

https://www.chinesechemsoc.org/doi/10.31635/ccschem.022.202202234              IF: 11.2

34. A general one-pot protocol for iron-catalyzed decarbonylative borylation of aryl and alkyl carboxylic acids 

Mei Bai,* Shasha Geng, Shuo Chen, Zhengli Liu, and Zhang Feng*

STAR Protocols. 2022, 3, 101909

https://www.sciencedirect.com/science/article/pii/S2666166722007894

33.  Undescribed specialised metabolites from the endophytic fungus Emericella sp. XL029 and their antimicrobial activities 

Peng-Jie Xiana, Shu-Zhi Liu, Wen-Jing Wang, Sheng-Xiang Yang, Zhang Feng*, Xiao-Long Yang*

Phytochemistry. 2022, 202, 113303

https://www.sciencedirect.com/science/article/pii/S0031942222002199

32. Boron-promoted reductive deoxygenation coupling reaction of sulfonyl chlorides for the C(sp3)-S bond construction 

Shuo Chen,# Qingru Wen,# Yanqing Zhu, Yanru Ji, Yu Pu,* Zhengli Liu, Yun He, Zhang Feng*

Chinese Chemical Letters 2022, DOI: 10.1016/j.cclet.2022.04.022              IF: 9.1 Q1

https://www.sciencedirect.com/science/article/pii/S1001841722003643

31. Boron-Promoted Umpolung Reaction of Sulfonyl Chlorides for the Stereospecific Synthesis of Thioglycosides via Reductive Deoxygenation Coupling Reactions 

Siyu Li,§ Yujuan Wang,§ Lei Zhong,§ Siyu Wang, Zhengli Liu, Yuanwei Dai,* Yun He,* and Zhang Feng*

Org. Lett. 2022, 24, 2463-2468

https://pubs.acs.org/doi/10.1021/acs.orglett.2c00353              IF: 5.2 Q1

 

30. Advances in Silylation and Borylation of fluoroarenes and gem-Difluoroalkenes via C-F bond 

Juan Zhang, Shasha Geng and Zhang Feng*

Chem. Commun., 2021, 57, 11922-11934

https://pubs.rsc.org/en/content/articlelanding/2021/cc/d1cc04729a

 

29. C-H Bond Borylation and Silylation via Iron Catalysis. Wiley-VCH, The Handbook of C-H Functionalization (Debabrata Maiti, Editor-in-Chief).

Juan Zhang, and Zhang Feng*.

28. Iron-Catalyzed C-F Bond Silylation and Borylation of Fluoroarenes 

Minghui Sun, # Maoling Tao, # Liang Zhao, Weipiao Li, Zhengli Liu, Chun-Yang He* and Zhang Feng*

Org. Chem. Front. 2021, 8, 5322-5327

https://pubs.rsc.org/en/content/articlelanding/2021/QO/D1QO00839K

27. Iron-Catalyzed Diborylation of Unactivated Aliphatic gem-Dihalogenoalkenes: Synthesis of 1,2-Bis(boryl)alkanes

Shangsheng Zhou, Yu Pu, Zhengli Liu, Xiaoming Zhang, Jiang Zhu*, and Zhang Feng*

Org. Lett. 2021, 23, 5565-5570

https://pubs.acs.org/doi/10.1021/acs.orglett.1c01967              IF: 5.2 Q1

26. Capsulactone: a new 4-hydroxy-α-pyrone derivative from an endophytic fungus Penicillium capsulatum and its antimicrobial activity

Peng-Jie Xian, Heng-Ye Chen, Zhang Feng*, Wei Zhao* and Xiao-Long Yang*

J. Asian. Nat. Prod. Res. 2021, 23, 1100-1106

https://www.tandfonline.com/doi/full/10.1080/10286020.2020.1847092              IF: 1.7 Q3

25. Experimental and Computational Studies on the Iron‐Catalyzed Selective and Controllable Defluorosilylation of Unactivated Aliphatic gem‐Difluoroalkenes

Huan Zhang,# Enhui Wang,# Shasha Geng,# Zhengli Liu, Yun He, Qian Peng* and Zhang Feng*

Angew. Chem. Int. Ed. 2021, 60, 10211

https://onlinelibrary.wiley.com/doi/10.1002/anie.202100049              IF: 16.6 Q1

24. A new fusicoccane diterpene and a new polyene from the plant endophytic fungus Talaromyces pinophilus and their antimicrobial activities   

Wen-Ting Zhao#, Xiong Shi#, Peng-Jie Xian, Zhang Feng*, Jian Yang* and Xiao-Long Yang*

Nat. Prod. Res., 2021, 35, 124.

https://www.tandfonline.com/doi/full/10.1080/14786419.2019.1616727?needAccess=true#aHR0cHM6Ly93d3cudGFuZGZvbmxpbmUuY29tL2RvaS9wZGYvMTAuMTA4MC8xNDc4NjQxOS4yMDE5LjE2MTY3Mjc/bmVlZEFjY2Vzcz10cnVlQEBAMA==

23. Iron-Catalyzed Cross-Coupling Reactions for the Construction of Carbon-Heteroatom Bonds

Juan Zhang, Siyu Wang, Yun Zhang, and Zhang Feng*

Asian J. Org. Chem., 2020, 9, 1519

(Invited review)

https://onlinelibrary.wiley.com/doi/full/10.1002/ajoc.202000334              IF: 2.7 Q2

22. Development and Mechanistic Studies of Iron-Catalyzed Construction of Csp2–B Bonds via C–O Bond Activation  

Shasha Geng, Juan Zhang, Shuo Chen, Zhengli Liu, Xiaoqin Zeng, Yun He, Zhang Feng*

Org. Lett., 2020, 22, 5582

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.0c01937              IF: 5.2 Q1

21. Iron-Catalyzed Borylation of Aryl Ethers via Cleavage of C−O Bonds   

Xiaoqin Zeng, Yuxuan Zhang, Zhengli Liu, Shasha Geng, Yun He, Zhang Feng*

Org. Lett., 2020, 22, 2950

(This article was among the most downloaded by readers of Organic Letters in April 2020.)

(This article was highlighted by Organic Process Research & Development 2020, 24, 874  )https://pubs.acs.org/doi/full/10.1021/acs.oprd.0c00197              IF: 3.4 Q1

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.0c00679              IF: 5.2 Q1

20. Iron-Catalyzed Borylation and Silylation of Unactivated Tertiary, Secondary and Primary Alkyl Chlorides

Siyu Wang#, Minghui Sun#, Huan Zhang, Juan Zhang, Yun He, and Zhang Feng*

CCS Chem. 2021, 3, 2164

https://www.chinesechemsoc.org/doi/10.31635/ccschem.020.202000447              IF: 11.2

19. Iron-Catalyzed Silylation of (Hetero)aryl Chlorides with Et3SiBpin   

Jia Jia,∥ Xiaoqin Zeng,∥ Zhengli Liu, Liang Zhao, Chun-Yang He,* Xiao-Fei Li,* and Zhang Feng*

Org. Lett., 2020, 22, 2816

(This article was highlighted by Organic Chemistry Portal)

https://www.organic-chemistry.org/abstracts/lit7/304.shtm

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.0c00809              IF: 5.2 Q1

18. C−O Bond Silylation Catalyzed by Iron: A General Method for the Construction of Csp2−Si Bonds 

Juan Zhang, Yun Zhang, Shasha Geng, Shuo Chen, Zhengli Liu, Xiaoqin Zeng, Yun He, and Zhang Feng*

Org. Lett., 2020, 22, 2669

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.0c00633              IF: 5.2 Q1

17. Thiyl Radical Promoted Iron-Catalyzed-Selective Oxidation of Benzylic Sp3 C-H Bonds with Molecular Oxygen 

Shasha Geng,# Baojian Xiong,# Yun Zhang,# Juan Zhang, Yun He,* and Zhang Feng*

Chem. Commun., 2019, 55, 12699

https://pubs.rsc.org/en/content/articlelanding/2019/CC/C9CC06584A#!divAbstract

 

16. Thiyl radical promoted chemo- and regioselective oxidation of C=C bonds using molecular oxygen via iron catalysis 

Baojian Xiong, Xiaoqin Zeng, Shasha Geng, Shuo Chen, Yun He* and Zhang Feng*

Green Chem., 2018, 20, 4521

https://pubs.rsc.org/en/content/articlelanding/2018/gc/c8gc02369g#!divAbstract

15. Transition-Metal (Cu, Pd, Ni)-Catalyzed Difluoroalkylation via Cross-Coupling with Difluoroalkyl Halides 

Zhang Feng, Yu-Lan Xiao and Xingang Zhang*

Acc. Chem. Res. 2018, 51, 2264.

https://pubs.acs.org/doi/10.1021/acs.accounts.8b00230              IF: 18.3 Q1

  

Pre-CQU Publications

 

******************************************************************

 

14.Chlorodifluoromethane Triggered Formation of Difluoromethylated (Hetero) Arenes Catalyzed by Palladium 

Zhang Feng†, Qiao-Qiao Min†, Xia-ping Fu†, and Xingang Zhang*

(†These authors contributed equally to this work)

(This paper was highlighted by Chemical & Engineering News, 2017, 95, 7 )https://pubs.acs.org/doi/10.1021/cen-09513-scicon004              

(This paper was highlighted by Molecule of the Week, 2017-06-19 )https://www.acs.org/molecule-of-the-week/archive/c/chlorodifluoromethane.html

(This paper was highlighted by Synthfacts, 2017, 9, 918 )https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0036-1591610?update=true

Nature Chemistry, 2017, 9, 918.

https://www.nature.com/articles/nchem.2746

 

13. Facile Access to Difluoromethylated Arenes by Pd-Catalyzed Reaction of Arylboronic Acids with Bromodifluoroacetate. 

Zhang Feng, Qiao-Qiao Min, and Xingang Zhang*

Org. Lett. 2016, 18, 44.

https://pubs.acs.org/doi/10.1021/acs.orglett.5b03206              IF: 5.2 Q1

 

12. Nickel-Catalyzed Reductive Cross-Coupling of (Hetero)Aryl Iodides with Fluorinated Secondary Alkyl Bromides. 

Xuefei Li, Zhang Feng, Zhong-Xing Jiang*,and Xingang Zhang*

Org. Lett. 2016, 17, 5570.

https://pubs.acs.org/doi/10.1021/acs.orglett.5b02716              IF: 5.2 Q1

 

11. Carbonylation of Difluoroalkyl Bromides Catalyzed by Palladium. 

Hai-Yang Zhao,Zhang Feng, Zhiji Luo,and Dr. Xingang Zhang*

Angew. Chem. Int. Ed. 2016, 128, 10577.

https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201605380              IF: 16.6 Q1

 

10. Palladium-catalyzed phosphonyldifluoromethylation of alkenes with bromodifluoromethylphosphonate. 

Zhang Feng, Yu-Lan Xiao, and Xingang Zhang*

Org.Chem. Front. 2016, 3, 466.

https://pubs.rsc.org/en/Content/ArticleLanding/2016/QO/C6QO00005C#!divAbstract

9. A General Synthesis of Fluoroalkylated Alkenes by Palladium-Catalyzed Heck-Type Reaction of Fluoroalkyl Bromides. 

Zhang Feng, Qiao-Qiao Min, Hai-Yang Zhao, Ji-Wei Gu, and Xingang Zhang*

Angew. Chem. Int. Ed. 2015, 54, 1270.

https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201409617              IF: 16.6 Q1

8. Palladium-Catalyzed Heck-Type Difluoroalkylation of Alkenes with Functionalized Difluoromethyl Bromides. 

Zhang Feng, Qiao-Qiao Min, and Xingang Zhang*

(Invited paper, Feature article)

Synthesis. 2015, 47, 2912.

https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0035-1560457              IF: 2.6 Q2

 

7. Palladium -Catalyzed Difluoroalkylation of Aryl Boronic Acids: A New Method for the Synthesis of Aryldifluoromethylated Phosphonates and Carboxylic Acid Derivatives. 

Zhang Feng, Qiao-Qiao Min, Yu-Lan Xiao, Bo Zhang, Xingang Zhang*

(This work was highlighted byC&EN, 2014, 92, 25 “Cross-Coupling Fluorinations Ramp Up”.)

Angew. Chem. Int. Ed. 2014, 53, 1669.

https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201309535              IF: 16.6 Q1

6. Copper Catalyzed Cross-Coupling Of Bromozinc-difluorophosphonate withIodo/Bromo-Aryl Triazenes. 

Zhang Feng, Yu-lan Xiao, Xingang Zhang*

(Top-20 most-cited Organic Chemistry Frontiers articles in 2014. Org. Chem. Front. 2015, 2, 9.)

Org.Chem. Front. 2014, 1, 113.

https://pubs.rsc.org/en/Content/ArticleLanding/2014/QO/C3QO00044C#!divAbstract

5. Heteroaryldifluoromethylation of Organoborons Catalyzed by Palladium: Facile Access to Aryl(Heteroaryl)difluoromethanes. 

Yu-Lan Xiao, Bo Zhang,Zhang Feng, and Xingang Zhang*

Org. Lett. 2014, 16, 4822.

https://pubs.acs.org/doi/10.1021/ol502121m              IF: 5.2 Q1

4. Highly Selective gem-Difluoroallylation of Organoborons with Bromodifluoromethylated Alkenes Catalyzed by Palladium. 

Qiao-Qiao Min, Zengsheng Yin,Zhang Feng, Wen-Hao Guo and Xingang Zhang*.

J. Am. Chem. Soc. 2014, 136, 1230.

https://pubs.acs.org/doi/10.1021/ja4114825              IF: 15.0 Q1

 

3. Copper Catalyzed Cross-Coupling of Iodobenzoates with Bromozinc-difluorophosphonate. 

Zhang Feng, Fei Chen, and Xingang Zhang*

(This paper was highlighted in Synfacts, 2012, 7, 0775 )

A DFT study of this reaction was reported by Jesús Jover (Organometallics 2018, 37, 327 )https://pubs.acs.org/doi/10.1021/acs.organomet.7b00739              IF: 2.8 Q2

Org. Lett. 2012, 14, 1938.

https://pubs.acs.org/doi/10.1021/ol3006425              IF: 5.2 Q1

2. Pd-Catalyzed Dehydrogenative Cross-Coupling of Polyfluoroarenes with Heteroatom-Substituted Enones. 

Fei Chen, Zhang Feng, Chun-Yang He, Hao-Yang Wang, Yin-long Guo, and Xingang Zhang*.

Org. Lett. 2012, 14, 1176.

https://pubs.acs.org/doi/10.1021/ol300240k              IF: 5.2 Q1

1. Highly Enantioselective Alkylation Reaction of Enamides by Brønsted-Acid Catalysis. 

Qi-Xiang Guo*, Yun-Gui Peng, Jin-Wei Zhang, Liu Song, Zhang Feng and Liu-Zhu Gong*.

Org. Lett. 2009, 11, 4620.

https://pubs.acs.org/doi/full/10.1021/ol901892s              IF: 5.2 Q1