Representative publications:
* [Equally contributed]; # [Corresponding author]
Dong, P. #, Zhang, S., Gandin, V., Xie, L., Wang, L., Lemire, L. L., L. W., Otsuna, H., Kawase, T., Lander, A.D., Chang, H. Y. & Liu, Z. # Cohesin prevents cross-domain gene co-activation. Nat Genet 56, 1654–1664 (2024).
Xie, L.*, Dong, P. *, Qi, Y., Hsieh, T. S., English, B. P., Jung, S., Chen, X., De Marzio, M., Casellas, R., Chang, H. Y., Zhang, B., Tjian, R. & Liu, Z. BRD2 compartmentalizes the accessible genome. Nat Genet 54, 481-491 (2022).
Xie, L.*, Dong, P. *, Chen, X., Hsieh, T. S., Banala, S., De Marzio, M., English, B. P., Qi, Y., Jung, S. K., Kieffer-Kwon, K. R., Legant, W. R., Hansen, A. S., Schulmann, A., Casellas, R., Zhang, B., Betzig, E., Lavis, L. D., Chang, H. Y., Tjian, R. & Liu, Z. 3D ATAC-PALM: super-resolution imaging of the accessible genome. Nat Methods 17, 430-436 (2020)
Cai, D., Feliciano, D., Dong, P., Flores, E., Gruebele, M., Porat-Shliom, N., Sukenik, S., Liu, Z. & Lippincott-Schwartz, J. Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression. Nat Cell Biol 21, 1578-1589 (2019).
Liu, H., Dong, P., Ioannou, M. S., Li, L., Shea, J., Pasolli, H. A., Grimm, J. B., Rivlin, P. K., Lavis, L. D., Koyama, M. & Liu, Z. Visualizing long-term single-molecule dynamics in vivo by stochastic protein labeling. Proc Natl Acad Sci U S A 115, 343-348 (2018).
Dong, P., Zhang, C., Parker, B. T., You, L. & Mathey-Prevot, B. Cyclin D/CDK4/6 activity controls G1 length in mammalian cells. PLoS One 13, e0185637 (2018).
Chong, S., Dugast-Darzacq, C., Liu, Z., Dong, P., Dailey, G. M., Cattoglio, C., Heckert, A., Banala, S., Lavis, L., Darzacq, X. & Tjian, R. Imaging dynamic and selective low-complexity domain interactions that control gene transcription. Science 361 (2018).
Dong, P. # & Liu, Z#. Shaping development by stochasticity and dynamics in gene regulation. Open Biol 7 (2017).
Dong, P., Maddali, M. V., Srimani, J. K., Thelot, F., Nevins, J. R., Mathey-Prevot, B. & You, L. Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control. Nat Commun 5, 4750 (2014).