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成果及论文

学术论文

Adv. Healthcare Mater.

2024, 2402

Adv. Healthcare Mater.

2024, 2402

Motor-Cargo Structured Nanotractors for Augmented NIR


Phototherapy via Gas-Boosted Tumor Penetration and
Respiration-Impaired Mitochondrial ction

2025年

16. Saurav Paramanya, Jin-Hyung Lee, Hailong Che, Jintae Lee, "Bromophenanthrenequinones as antimicrobial and antibiofilm agents againstStaphylococcus aureus", Biomed. Pharmacother.2025, 189, 118270.

15. Shaofeng Feng#, Yuzhe Ma#, Zhezhe Li, Suzhen Wang,  Lili Zhao, Jintae Lee and Hailong Che*, "Constructing Polycarbonate-Based Oxidation-Responsive Polymersome Nanoreactors with Tunable Biocatalysis", Macromolecules, 2025 5811, 5772-5781.

14. Baohua Zhang#, Shuyang Shen#, Suzhen Wang, Zhezhe Li, Yuzhe Ma, Siyu Song* and Hailong Che*, "Construction of Nitric Oxide-Releasing Poly(trimethylene carbonate)-Based Polymersomes Equipped with Cell-Penetrating Guanidine",  Chem. Mater., 2025, 37, 3434-3442. 

13. Siyu Song, Hao Han, Jianhong Wang, Yubin Pu, Jingxin Shao, Jing Xie* Hailong Che*, Jan C. M. van Hest * and Shoupeng Cao*, "Polymersome-based Nanomotors: Preparation, Motion Control, and Biomedical Applications", Chem. Sci.2025, 16, 7106-7129.

12. Jing Wang, Hejingying Niu, Huadong Chen, Shanshan Yuan, Shanshan Zheng, Tonghan Zhao, Yihan Wu, Jinliang Liu, Hailong Che, Yong Zhang  and Xiaohui Zhu, "Achieving Precision Phototherapy from Start to Finish: Integrating Endosomal Escape, Respiration Inhibition, and ROS Release in a Single Upconversion Nanoparticle", Small Methods, 2025, 2401742.

Small Methods

2025, 2401742

Jing Wang, Hejingying Niu, Huadong Chen, Shanshan Yuan, Shanshan Zheng,


Tonghan Zhao, Yihan Wu, Jinliang Liu, Hailong Che, Yong Zhang,* and Xiaohui Zhu*

Jing Wang, Hejingying Niu, Huadong Chen, Shanshan Yuan, Shanshan Zheng,


Tongha Zhao, Yihan Wu, Jinliang Liu, Hailong Che, Yong Zhang,* and Xiaohui Zhu*

11. Lili Zhao#, Suzhen Wang#, Zhezhe Li, Jian Gu* and Hailong Che*, "Constructing pH-responsive poly(trimethylene carbonate) (PTMC)-based polymersomes functionalized with cell-penetrating  guanidines", Polym. Chem.2025, 16, 1875-1883.

10.  Kai Jin, Yi Huang, Hailong Che and Yihan Wu, "Engineered Bacteria for Disease Diagnosis and Treatment Using Synthetic Biology", Microbial Biotechnology, 2025, 18:e70080.

09.  Suzhen Wang, Zhezhe Li, Lili Zhao, Yuerong Lin and Hailong Che*"Polycarbonate-Based Polymersome Photosensitizers with Cell-Penetrating Properties for Improved Killing of Cancer Cells", Biomacromolecules2025, 26, 1251-1259.


2024年

08. Zhezhe Li#, Yue Zhang#, Suzhen Wang, Yihan Wu and Hailong Che*, "Rational Design of Self-Reporting Polymersomes for the Controlled Release of Sulfur Dioxide ", ACS Macro Lett.2024, 13,1691-1697.

07. Jing Wang, Yi Zhang, Huadong Chen, Yihan Wu, Jinliang Liu, Hailong Che, Yong Zhang and Xiaohui Zhu, "Motor-Cargo Structured Nanotractors for Augmented NIR Phototherapy via Gas-Boosted Tumor Penetration and Respiration-Impaired Mitochondrial Dysfunction", Adv. Healthcare. Mater., 2024, 2402063.

06. Zhezhe Li, Suzhen Wang, Lili Zhao, Shaofeng Feng and Hailong Che*"Synthesis and Characterization of Guanidinylated CO-Releasing Micelles Based on Biodegradable Polycarbonate", Biomacromolecules2024, 25, 5149-5159.

05. Yanyan Zhu, Zhezhe Li, Suzhen Wang, Jian Gu, Rui L. Reis and Hailong Che*, "Synthesis and characterization of light-responsive biodegradable tubular polymersomes", Polym. Chem., 2024, 15, 1026-1033.

04. Zhezhe Li, Suzhen Wang, Lili Zhao, Jian Gu and Hailong Che*, "Nitric Oxide-Releasing Tubular Polymersomes toward Advanced Gas Therapeutic Carriers", ACS Macro Lett., 2024, 13, 87-93.


2023年

03. Yanyan Zhu#, Shoupeng Cao#, Meng Huo*, Jan C. M. van Hest* and Hailong Che*, "Recent advances in permeable polymersomes: fabrication, responsiveness, and applications", Chem. Sci., 2023,14, 7411-7437.


2022年

02. Linlin Fan, Zhong Zeng, Ruixue Zhu, Aiping Liu*, Hailong Che* and Meng Huo*, “Polymerization-induced self-assembly toward micelle-crosslinked tough and ultrastretchable hydrogels”, Chem. Mater., 2022, 34, 6408-6419.

01. Hailong Che* and Jinying Yuan, “Recent advances in electrospinning supramolecular systems”, J. Mater. Chem. B, 2022,10, 8-19.


Before SHU

17.  Jingxin Shao, Shoupeng Cao, Hailong Che, Maria Teresa De Martino, Hanglong Wu, Loai K. E. A. Abdelmohsen*, and Jan C. M. van Hest*, “Twin-engine janus supramolecular nanomotors with counterbalanced motion”, J. Am. Chem. Soc., 2022, 144, 11246−11252.

16.  Tingting Xiao, Jianzhi Zhu, Liang Jia, Hailong Che, Jie Liu, J. Deckers, Jan C.M. van Hest*, and Xiangyang Shi*, “Injectable alginate hydrogels for synergistic tumor combination therapy through repolarization of tumor-associated macrophages”, J. Control. Release, 2022, 348, 239–249

15.  Hailong Che, Lafayette N. J. de Windt, Jianzhi Zhu, Imke Pijpers, Alexander Mason, Loai Abdelmohsen*, Jan C. M. van Hest*, “Pathway dependent shape-transformation of azide-decorated polymersomes”, Chem. Commun., 2020, 56, 2127-2130.

14.  Jianzhi Zhu, Tingting Xiao, Jiulong Zhang, Hailong Che, Yuxin Shi, Xiangyang Shi*, Jan C. M. van Hest*, “Surface-charge-switchable nanoclusters for magnetic resonance imaging-guided and glutathione depletion-enhanced photodynamic therapy”, ACS Nano, 2020, 14, 11225-11237.

13.  Yigit Altay, Shoupeng Cao, Hailong Che, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest*, “Adaptive polymeric assemblies for applications in biomimicry and nanomedicine”, Biomacromolecules, 2019, 20, 4053-4064.

12.  Jianzhi Zhu, Zhicong Li, Changchang Zhang, Lizhou Lin, Shoupeng Cao, Hailong Che, Xiangyang Shi, Han Wang*, Jan C.M. van Hest*, “Single enzyme loaded nanoparticles for combinational ultrasound-guided focused ultrasound ablation and hypoxia-relieved chemotherapy”, Theranostics, 2019, 9,8048.

11.  Shoupeng Cao, Jingxin Shao, Yifeng Xia, Hailong Che, Zhiyuan Zhong, Fenghua Meng, Jan C. M. van Hest,* Loai K. E. A. Abdelmohsen,* David S. Williams*, “Molecular Programming of biodegradable nanoworms via ionically-induced morphology switch towards asymmetric therapeutic carriers”, Small, 2019, 15, 1901849.

10.  Hailong Che, Jianzhi Zhu, Shidong Song, Alexander Mason, Shoupeng Cao, Imke Pijpers, Loai Abdelmohsen*, Jan C. M. van Hest*, “ATP-mediated transient behavior of stomatocyte nanosystems”, Angew. Chem. Int. Ed., 2019, 58, 13113-13118. 

09. Hailong Che, Jan C. M. van Hest*, “Adaptive polymersome nanoreactros”, ChemNanoMat, 2019, 5, 1092-1109.

08. Hailong Che, Shoupeng Cao, Jan C. M. van Hest*, “Feedback-induced temporal control of “breathing” polymersomes to create self-adaptive nanoreactors”, J. Am. Chem. Soc., 2018, 140, 5356-5359.

07.  Meng Huo, Qiquan Ye, Hailong Che, Xiaosong Wang*, Yen Wei*, Jinying Yuan*, “Polymer assemblies with nanostructure-correlated aggregation-induced emission”, Macromolecules2017, 50, 1126-1133.

06.  Hailong Che, Jinying Yuan*, “CO2-responsive bowl-shaped polymersomes”, Macromol. Res., 2017, 25, 635-639. 

05.  Hailong Che, Bastiaan C. Buddingh,, Jan C. M. van Hest*, “Self-regulated and temporal control of a “breathing” microgel mediated by enzymatic reaction", Angew. Chem. Int. Ed., 2017, 56, 12581-12585. 

04.  Hailong Che, Jan C. M. van Hest*, “Stimuli-responsive polymersomes and nanoreactors”, J. Mater. Chem. B, 2016, 4, 4632-4647. 

03.  Meng Huo, Qiquan Ye, Hailong Che, Mengzhen Sun, Jinying Yuan*, Yen Wei*, “Synthesis and self-assembly of CO2-responsive dendronized triblock copolymers”, Polym. Chem., 2015, 6, 7427-7435. 

02.  Hailong Che, Meng Huo, Liao Peng, Tommy Fang, Na Liu, Lin Feng, Yen Wei, Jinying Yuan*, “CO2-responsive nanofibrous membranes with switchable oil/water wettability", Angew. Chem. Int. Ed., 2015, 54, 8934-8938. 

01.  Hailong Che, Meng Huo, Liao Peng, Qiquan Ye, Jun Guo, Ke Wang, Yen Wei, Jinying Yuan*, “CO2-switchable drug release from magneto-polymeric nanohybrids”, Polym. Chem., 2015, 6, 2319-2326.


专著

01.  Hailong Che, Jinying Yuan*. RSC Publishing, 2019, Smart Materials: Smart Membranes, Chapter 6, CO2-responsive Membranes, 159-184. 


专利

01.  袁金颖,车海龙,霍猛,彭了,方立城,刘娜,冯琳,危岩。“一种具有CO2刺激响应的油水分离纳米纤维膜及其制备方法与应用”。专利号:ZL 2015 1 0242944.4