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成果及论文

2022年


108. Yang, L.; Wu, G.; Meng, F.; Ran, H.; Yin, W.-B.; Li, W.; Liu, X., Combination Strategy of Genetic Dereplication and Manipulation of Epigenetic Regulators Reveals a Novel Compound from Plant Endophytic Fungus. Int J Mol Sci 2022, 23 (7).

107. Wang, G.; Ran, H.; Fan, J.; Keller, N.; Liu, Z.; Wu, F.; Yin, W.-B.*, Fungal-fungal cocultivation leads to widespread secondary metabolite alteration requiring the partial loss-of-function VeA1 protein. Sci adv 2022, 8, eabo6094.

106. Han, J.; Baosong, C.; Zhang, R.; Zhang, J.; Huanqin, D.; Wang, T.; Sun, J.; Zhu, G.; Li, W.; Li, E.; Liu, X.; Yin, W.-B.; Liu, H. *, Exploring Verrucosidin Derivatives with Glucose-Uptake-Stimulatory Activity from Penicillium cellarum Using MS/MS-Based Molecular Networking. J Fungi (Basel) 2022, 8, 143.

105. Zhang, Z. X.; Li, Z. H.; Yin, W.-B.; Li, S. M.*, Biosynthesis of viridicatol in Penicillium palitans implies a cytochrome P450-mediated meta hydroxylation at a monoalkylated benzene ring. Org Lett 2022, 24 (1), 262-267.


2021年:

 

104. Zhang, J. Y.; Qi, L. D.; Chen, G. C.; Yin, W.-B.*, Discovery and genetic identification of amphiphilic coprogen siderophores from Trichoderm hypoxylon. Appl Microbiol Biot 2021.

103. Zhang, J.; Zhang, P.; Zeng, G.; Wu, G.; Qi, L.; Chen, G.; Fang, W.; Yin, W.-B. *, Transcriptional differences guided discovery and genetic identification of coprogen and dimerumic acid siderophores in Metarhizium robertsii. Front Microbiol 2021, 12, 783609.

102. Zhang, J.; Yin, W.-B.*, Characterisation of two unique sesquiterpenoids from Trichoderma hypoxylon. Mycology 2021, 1-7.

101. Xu, X.; Huang, R.; Yin, W.-B.*, An optimized and efficient CRISPR/Cas9 system for the endophytic fungus Pestalotiopsis fici. J Fungi (Basel) 2021, 7 (10).

100. Xu, X.; Feng, J.; Zhang, P.; Fan, J.; Yin, W.-B. *, A CRISPR/Cas9 cleavage system for capturing fungal secondary metabolite gene clusters. J Microbiol Biotechn 2021, 31 (1), 8-15.

99. Song, Z.; Zhao, R.; Zhang, H.; Wei, P.; Qi, L.; Chen, G.; Yin, W.-B. *; Li, W. *, Rapid and accurate screening of lysine-producing edible mushrooms via the homocitrate synthase gene as a universal molecular marker. ACS Omega 2021, 6 (41), 26910-26918.

98. Song, Z.; He, M.; Zhao, R.; Qi, L.; Chen, G.; Yin, W.-B. *; Li, W. *, Molecular evolution of lysine biosynthesis in Agaricomycetes. J Fungi (Basel) 2021, 8 (1).

97. Ma, K.; Zhang, Y. T.; Guo, C.; Yang, Y. L.; Han, J. J.; Yu, B.; Yin, W.-B.; Liu, H. W.*, Reconstitution of biosynthetic pathway for mushroom-derived cyathane diterpenes in yeast and generation of new "non-natural" analogues. Acta Pharm Sin B 2021, 11 (9), 2945-2956.

96. Lyu, H. N.; Zhang, J.; Zhou, S.; Liu, H. W.; Zhuang, W. Y.; Li, S. M.; Yin, W.-B.*, Heterologous expression of a single fungal HR-PKS leads to the formation of diverse 2-alkenyl-tetrahydropyrans in model fungi. Org Biomol Chem 2021, 19 (38), 8377-8383.

95. Liu, Z. G.; Li, W.; Zhang, P.; Fan, J.; Zhang, F. B.; Wang, C. X.; Li, S. M.; Sun, Y.; Chen, S. L. *; Yin, W.-B.*, Tricarbocyclic core formation of tyrosine-decahydrofluorenes implies a three-enzyme cascade with XenF-mediated sigmatropic rearrangement as a prerequisite. Acta Pharm Sin B 2021, 11 (11), 3655-3664.

94. Liu, H.; Fan, J.; Zhang, P.; Hu, Y. C.; Liu, X. Z.; Li, S. M. *; Yin, W.-B.*, New insights into the disulfide bond formation enzymes in epidithiodiketopiperazine alkaloids. Chem Sci 2021, 12 (11), 4132-4138.

93. Liang, M.; Lyu, H. N.; Ma, Z. Y.; Li, E. W.; Cai, L. *; Yin, W.-B.*, Genomics-driven discovery of a new cyclodepsipeptide from the guanophilic fungus Amphichorda guana. Org Biomol Chem 2021, 19 (9), 1960-1964.

92. Liang, M.; Li, W.; Qi, L.; Chen, G.; Cai, L.; Yin, W.-B.*, Establishment of a genetic transformation system in guanophilic fungus Amphichorda guana. J Fungi (Basel) 2021, 7 (2).

91. Li, W.; Fan, J.; Liao, G.; Yin, W.-B.; Li, S. M.*, Precursor supply increases the accumulation of 4-hydroxy-6-(4-hydroxyphenyl)-alpha-pyrone after NRPS-PKS gene expression. J Nat Prod 2021.

90. Hou, B.; Liu, S.; Huo, R.; Li, Y.; Ren, J.; Wang, W.; Wei, T.; Jiang, X.; Yin, W.-B.; Liu, H.; Liu, L.*; Li, E.*, New diterpenoids and isocoumarin derivatives from the mangrove-derived fungus Hypoxylon sp. Mar Drugs 2021, 19 (7).

89. Guo, Q. F.; Chen, J. H.; Ren, Y. W.; Yin, Z. H.; Zhang, J. J.; Yang, B. C.; Wang, X. W.; Yin, W.-B.;  Zhang, W. C. *; Ding, G. *; Chen, L. *, Hydrazine-containing heterocycle cytochalasan derivatives from hydrazinolysis of extracts of a desert soil-derived fungus Chaetomium madrasense 375. Front Chem 2021, 9.

88. Bakany, B.; Yin, W.-B.; Dienes, B.; Nagy, T.; Leiter, E.; Emri, T.; Keller, N. P. *; Pocsi, I. *, Study on the bZIP-type transcription factors NapA and RsmA in the regulation of intracellular reactive species levels and sterigmatocystin production of Aspergillus nidulans. Int J Mol Sci 2021, 22 (21).

 

2020年:

 

87. Xiang, P.; Ludwig-Radtke, L.; Yin, W.-B.; Li, S. M. *, Isocoumarin formation by heterologous gene expression and modification by host enzymes. Org Biomol Chem 2020, 18 (26), 4946-4948.

86. Nies, J.; Ran, H.; Wohlgemuth, V.; Yin, W.-B.; Li, S. M.*, Biosynthesis of the prenylated salicylaldehyde flavoglaucin requires temporary reduction to salicyl alcohol for decoration before reoxidation to the final product. Org Lett 2020, 22 (6), 2256-2260.

85. Lyu, H. N.; Liu, H. W.; Keller, N. P.; Yin, W.-B.*, Harnessing diverse transcriptional regulators for natural product discovery in fungi. Nat Prod Rep 2020, 37 (1), 6-16.

84. Liu, H.; Pu, Y. H.; Ren, J. W.; Li, E. W.; Guo, L. X.; Yin, W.-B.*, Genetic dereplication driven discovery of a tricinoloniol acid biosynthetic pathway in Trichoderma hypoxylon. Org Biomol Chem 2020, 18 (28), 5344-5348.

83. Fan, J.; Liao, G.; Ludwig-Radtke, L.; Yin, W.-B.; Li, S. M.*, Formation of terrestric acid in Penicillium crustosum requires redox-assisted decarboxylation and stereoisomerization. Org Lett 2020, 22 (1), 88-92.

 

2019年:

 

82. Zhou, S.; Zhang, P.; Zhou, H.; Liu, X.; Li, S. M.; Guo, L.; Li, K.; Yin, W.-B.*, A new regulator RsdA mediating fungal secondary metabolism has a detrimental impact on asexual development in Pestalotiopsis fici. Environ Microbiol 2019, 21 (1), 416-426.

81. Zhang, P.; Zhou, S.; Wang, G.; An, Z.; Liu, X.; Li, K.; Yin, W.-B.*, Two transcription factors cooperatively regulate DHN melanin biosynthesis and development in Pestalotiopsis fici. Mol Microbiol 2019, 112 (2), 649-666.

80. Wang, J.; Zhang, Y.; Liu, H.; Shang, Y.; Zhou, L.; Wei, P.; Yin, W.-B.; Deng, Z.; Qu, X. *; Zhou, Q.*, A biocatalytic hydroxylation-enabled unified approach to C19-hydroxylated steroids. Nat Commun 2019, 10 (1), 3378.

79. Ma, K.; Zhang, P.; Tao, Q.; Keller, N. P.; Yang, Y.; Yin, W.-B.*; Liu, H. *, Characterization and biosynthesis of a rare fungal hopane-type triterpenoid glycoside involved in the antistress property of Aspergillus fumigatus. Org Lett 2019, 21 (9), 3252-3256.

78. Li, W.; Yu, J.; Li, Z.; Yin, W.-B. *, Rational design for fungal laccase production in the model host Aspergillus nidulans. Sci China Life Sci 2019, 62 (1), 84-94.

77. Li, W.; Yin, W.-B.*, Genetic mining of the "dark matter" in fungal natural products. Sci China Life Sci 2019, 62 (9), 1250-1252.

76. Li, R.; Li, Z.; Ma, K.; Wang, G.; Li, W.; Liu, H. W.; Yin, W.-B.*; Zhang, P. *; Liu, X. Z. *, Strategy for efficient cloning of biosynthetic gene clusters from fungi. Sci China Life Sci 2019, 62 (8), 1087-1095.

75. Fan, J.; Liao, G.; Kindinger, F.; Ludwig-Radtke, L.; Yin, W.-B.; Li, S. M. *, Peniphenone and penilactone formation in Penicillium crustosum via 1,4-Michael additions of ortho-quinone methide from hydroxyclavatol to gamma-butyrolactones from crustosic acid. J Am Chem Soc 2019, 141 (10), 4225-4229.

74. Chen, L.; Wu, H.; Liu, H.; Li, E.; Ren, J.; Wang, W.; Wang, S.; Yin, W.-B.*, Genetic dereplication of Trichoderma hypoxylon reveals two novel polycyclic lactones. J Asian Nat Prod Res 2019, 91, 103185.

73. Chen, L.; Wu, G. W.; Liu, D.; Zhuang, W. Y.; Yin, W.-B.*, Trichodermatides E and F from fungus Trichoderma applanatum. J Asian Nat Prod Res 2019, 21 (7), 659-665.

 

2018年:

 

72. Zeng, G.; Zhang, P.; Zhang, Q.; Zhao, H.; Li, Z.; Zhang, X.; Wang, C.; Yin, W.-B.; Fang, W.*, Duplication of a Pks gene cluster and subsequent functional diversification facilitate environmental adaptation in Metarhizium species. PLoS Genet 2018, 14 (6), e1007472.

71. Wang, Y.; Wang, L.; Wu, F.; Liu, F.; Wang, Q.; Zhang, X.; Selvaraj, J. N.; Zhao, Y.; Xing, F.; Yin, W.-B.; Liu, Y.*, A consensus ochratoxin A biosynthetic pathway: insights from the genome sequence of Aspergillus ochraceus and a comparative genomic analysis. Appl Environ Microbiol 2018, 84 (19).

70. Wang, S. S.; Cui, H.; Ye, J.; Wu, Y.; Wang, S. X.; Yin, W.-B.*, Identification and determination of rubrofusarin, rubrofusarin isomer, and their quinone forms in grains using high-resolution mass spectrometry. ACS Omega 2018, 3 (11), 15924-15932.

69. Ma, Z.; Li, W.; Zhang, P.; Lyu, H.; Hu, Y.; Yin, W.-B.*, Rational design for heterologous production of aurovertin-type compounds in Aspergillus nidulans. Appl Environ Microbiol 2018, 102 (1), 297-304.

68. Liu, Z. G.; Bao, L.; Liu, H. W.; Ren, J. W.; Wang, W. Z.; Wang, L.; Li, W.; Yin, W.-B.*, Chemical diversity from the Tibetan Plateau fungi Penicillium kongii and P. brasilianum. Mycology 2018, 9 (1), 10-19.

67. Liu, L.; Bao, L.; Wang, L.; Ma, K.; Han, J. J.; Yang, Y. L.; Liu, R. X.; Ren, J. W.; Yin, W.-B.;  Wang, W. Z.; Liu, H. W.*, Asperorydines A-M: prenylated tryptophan-derived alkaloids with neurotrophic effects from Aspergillus oryzae. J Org Chem 2018, 83 (2), 812-822.

66. Yang, Y.; Zhang, Y.; Zhang, S.; Chen, Q.; Ma, K.; Bao, L.; Tao, Y.; Yin, W.-B.; Wang, G.; Liu, H., Identification and characterization of a membrane-bound sesterterpene cyclase from Streptomyces somaliensis. J Nat Prod 2018, 81 (4), 1089-1092.

65. Liu, H.; Wang, G.; Li, W.; Liu, X.; Li, E.; Yin, W.-B.*, A highly efficient genetic system for the identification of a harzianum B biosynthetic gene cluster in Trichoderma hypoxylon. Microbiology 2018, 164 (5), 769-778.

64. Lin, H.; Lyu, H.; Zhou, S.; Yu, J.; Keller, N. P.; Chen, L.; Yin, W.-B.*, Deletion of a global regulator LaeB leads to the discovery of novel polyketides in Aspergillus nidulans. Org Biomol Chem 2018, 16 (27), 4973-4976.

63. Li, W.; Ma, Z.; Chen, L.; Yin, W.-B.*, Synthesis and production of the antitumor polyketide aurovertins and structurally related compounds. Appl Environ Microbiol 2018, 102 (15), 6373-6381.

62. Li, W.; Fan, A.; Wang, L.; Zhang, P.; Liu, Z.; An, Z.; Yin, W.-B.*, Asperphenamate biosynthesis reveals a novel two-module NRPS system to synthesize amino acid esters in fungi. Chem Sci 2018, 9 (9), 2589-2594.

 

2017年:

 

61. Zheng, Y.; Wang, X.; Zhang, X.; Li, W.; Liu, G.; Wang, S.; Yan, X.; Zou, H.*; Yin, W.-B.*, COP9 signalosome subunit PfCsnE regulates secondary metabolism and conidial formation in Pestalotiopsis fici. Sci China Life Sci 2017, 60 (6), 656-664.

60. Zheng, Y.; Ma, K.; Lyu, H.; Huang, Y.; Liu, H.; Liu, L.; Che, Y.; Liu, X.; Zou, H.; Yin, W.-B.*, Genetic manipulation of the COP9 signalosome subunit PfCsnE leads to the discovery of pestaloficins in Pestalotiopsis fici. Org Lett 2017, 19 (17), 4700-4703.

59. Zhao, W.; Fan, A.; Tarcz, S.; Zhou, K.; Yin, W.-B.; Liu, X. Q.*; Li, S. M.*, Mutation on Gly115 and Tyr205 of the cyclic dipeptide C2-prenyltransferase FtmPT1 increases its catalytic activity toward hydroxynaphthalenes. Appl Microbiol Biot 2017, 101 (5), 1989-1998.

58. Zhang, P.; Wang, X.; Fan, A.; Zheng, Y.; Liu, X.; Wang, S.; Zou, H.; Oakley, B. R.; Keller, N. P.; Yin, W.-B.*, A cryptic pigment biosynthetic pathway uncovered by heterologous expression is essential for conidial development in Pestalotiopsis fici. Mol Microbiol 2017, 105 (3), 469-483.

57. Yang, Y. L.; Zhang, S.; Ma, K.; Xu, Y.; Tao, Q.; Chen, Y.; Chen, J.; Guo, S.; Ren, J.; Wang, W.;  Tao, Y.; Yin, W.-B.; Liu, H.*, Discovery and characterization of a new family of diterpene cyclases in bacteria and fungi. Angew Chem Int Ed 2017, 56 (17), 4749-4752.

56. Liu, L.; Wang, L.; Bao, L.; Ren, J.; Bahadur B., B.; Liu, R.; He, L.; Han, J.; Yin, W.-B.; Liu, H. W.*, Versicoamides F-H, prenylated indole alkaloids from Aspergillus tennesseensis. Org Lett 2017, 19 (4), 942-945.

55. Han, J.; Liu, C.; Li, L.; Zhou, H.; Liu, L.; Bao, L.; Chen, Q.; Song, F.; Zhang, L.; Li, E.; Liu, L.;  Pei, Y.; Jin, C.; Xue, Y.; Yin, W.-B.; Ma, Y.; Liu, H. W.*, Decalin-containing tetramic acids and 4-hydroxy-2-pyridones with antimicrobial and cytotoxic activity from the fungus Coniochaeta cephalothecoides collected in Tibetan Plateau (Medog). J Org Chem 2017, 82 (21), 11474-11486.

54. Feng, J.; Zhang, P.; Cui, Y. L.; Li, K.; Qiao, X.; Zhang, Y. T.; Li, S. M.; Cox, R. J.; Wu, B.; Ye, M.*; Yin, W.-B.*, Regio- and stereospecific O-glycosylation of phenolic compounds catalyzed by a fungal glycosyltransferase from Mucor hiemalis. Adv Synth Catal 2017, 359 (6), 995-1006.

53. Fan, A.; Mi, W.; Liu, Z.; Zeng, G.; Zhang, P.; Hu, Y.; Fang, W.; Yin, W.-B.*, Deletion of a histone acetyltransferase leads to the pleiotropic activation of natural products in Metarhizium robertsii. Org Lett 2017, 19 (7), 1686-1689.

 

2016年:

 

52. Han, X.; Qiu, M.; Wang, B.; Yin, W.-B.; Nie, X.; Qin, Q.; Ren, S.; Yang, K.; Zhang, F.; Zhuang, Z.; Wang, S.*, Functional analysis of the nitrogen metabolite repression regulator gene nmrA in Aspergillus flavus. Front Microbiol 2016, 7, 1794.

51. Sun, J.; Pei, Y.; Li, E.; Li, W.; Hyde, K. D.; Yin, W.-B.*; Liu, X.*, A new species of Trichoderma hypoxylon harbours abundant secondary metabolites. Sci Rep 2016, 6, 37369.

50. Tao, Q.; Ma, K.; Yang, Y.; Wang, K.; Chen, B.; Huang, Y.; Han, J.; Bao, L.; Liu, X. B.; Yang, Z.;  Yin, W.-B.; Liu, H.*, Bioactive sesquiterpenes from the edible mushroom Flammulina velutipes and their biosynthetic pathway confirmed by genome analysis and chemical evidence. J Org Chem 2016, 81 (20), 9867-9877.

49. Wang, G.; Liu, Z.; Lin, R.; Li, E.; Mao, Z.; Ling, J.; Yang, Y.; Yin, W.-B.*; Xie, B.*, Biosynthesis of antibiotic leucinostatins in bio-control fungus Purpureocillium lilacinum and their inhibition on Phytophthora revealed by genome mining. PLoS Pathog 2016, 12 (7), e1005685.

48. Wang, K.; Bao, L.; Ma, K.; Qi, W.; Song, F.; Yao, Y.; Yin, W.-B.; Zhang, L.; Huang, Y.; Han, J.; Liu, H.*, Bioactive spirobisnaphthalenes and lactones from a cup fungus Plectania sp. collected in the Tibet Plateau region. Eur J Org Chem 2016, 2016 (25), 4338-4346.

47. Wu, G.; Zhou, H.; Zhang, P.; Wang, X.; Li, W.; Zhang, W.; Liu, X.; Liu, H. W.; Keller, N. P.; An, Z.; Yin, W.-B.*, Polyketide production of pestaloficiols and macrodiolide ficiolides revealed by manipulations of epigenetic regulators in an endophytic fungus. Org Lett 2016, 18 (8), 1832-1835.

 

2015年:

 

46. Wang, X.; Zhang, X.; Liu, L.; Xiang, M.; Wang, W.; Sun, X.; Che, Y.; Guo, L.; Liu, G.; Guo, L.;  Wang, C.; Yin, W.-B.; Stadler, M.; Zhang, X.*; Liu, X.*, Genomic and transcriptomic analysis of the endophytic fungus Pestalotiopsis fici reveals its lifestyle and high potential for synthesis of natural products. BMC Genomics 2015, 16, 28.

45. Wang, X.; Wu, F.; Liu, L.; Liu, X.; Che, Y.; Keller, N. P.; Guo, L.*; Yin, W.-B.*, The bZIP transcription factor PfZipA regulates secondary metabolism and oxidative stress response in the plant endophytic fungus Pestalotiopsis fici. Fungal Genet Biol 2015, 81, 221-228.

44. Wang, L.; Feng, Y.; Tian, J.; Xiang, M.; Sun, J.; Ding, J.; Yin, W.-B.; Stadler, M.; Che, Y.; Liu, X.*, Farming of a defensive fungal mutualist by an attelabid weevil. ISME J 2015, 9 (8), 1793-1801.

43. Wang, K.; Bao, L.; Xiong, W.; Ma, K.; Han, J.; Wang, W.; Yin, W.-B.; Liu, H.*, Lanostane triterpenes from the tibetan medicinal mushroom Ganoderma leucocontextum and their inhibitory effects on HMG-CoA reductase and alpha-glucosidase. J Nat Prod 2015, 78 (8), 1977-1989.

42. Wang, C.*; Lu, L.*; Yin, W.-B.*; Zhang, K. Q.*, From taxonomy and industry to genetics: fungal biology in China. Fungal Genet Biol 2015, 81, 110-112.

41. Qi, Q. Y.; Ren, J. W.; Sun, L. W.; He, L. W.; Bao, L.; Yue, W.; Sun, Q. M.; Yao, Y. J.; Yin, W.-B.; Liu, H. W.*, Stucturally diverse sesquiterpenes produced by a Chinese Tibet fungus Stereum hirsutum and their cytotoxic and immunosuppressant activities. Org Lett 2015, 17 (12), 3098-3101.

40. Mao, X. M.; Zhan, Z. J.; Grayson, M. N.; Tang, M. C.; Xu, W.; Li, Y. Q.; Yin, W.-B.; Lin, H. C.;  Chooi, Y. H.; Houk, K. N.; Tang, Y.*, Efficient biosynthesis of fungal polyketides containing the dioxabicyclo-octane ring system. J Am Chem Soc 2015, 137 (37), 11904-11907.

39. Mao, X. M.; Xu, W.; Li, D.; Yin, W.-B.; Chooi, Y. H.; Li, Y. Q.; Tang, Y.*; Hu, Y.*, Epigenetic genome mining of an endophytic fungus leads to the pleiotropic biosynthesis of natural products. Angew Chem Int Ed 2015, 54 (26), 7592-7596.

38. Han, J. J.; Bao, L.; Tao, Q. Q.; Yao, Y. J.; Liu, X. Z.; Yin, W.-B.; Liu, H. W.*, Gloeophyllins A-J, cytotoxic ergosteroids with various skeletons from a Chinese Tibet fungus Gloeophyllum abietinum. Org Lett 2015, 17 (10), 2538-2541.

 

2010-2014年:

 

37. Wiemann, P.; Lechner, B. E.; Baccile, J. A.; Velk, T. A.; Yin, W.-B.; Bok, J. W.; Pakala, S.;  Losada, L.; Nierman, W. C.; Schroeder, F. C.; Haas, H.; Keller, N. P.*, Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus. Front Microbiol 2014, 5, 530.

36. Hu, Y.; Dietrich, D.; Xu, W.; Patel, A.; Thuss, J. A.; Wang, J.; Yin, W.-B.; Qiao, K.; Houk, K. N.;  Vederas, J. C.*; Tang, Y.*, A carbonate-forming Baeyer-Villiger monooxygenase. Nat Chem Biol 2014, 10 (7), 552-554.

35. Yin, W.-B.; Reinke, A. W.; Szilagyi, M.; Emri, T.; Chiang, Y. M.; Keating, A. E.; Pocsi, I.; Wang, C. C.; Keller, N. P.*, bZIP transcription factors affecting secondary metabolism, sexual development and stress responses in Aspergillus nidulans. Microbiology 2013, 159 (Pt 1), 77-88.

34. Yin, W.-B.; Chooi, Y. H.; Smith, A. R.; Cacho, R. A.; Hu, Y.; White, T. C.; Tang, Y.*, Discovery of cryptic polyketide metabolites from dermatophytes using heterologous expression in Aspergillus nidulans. ACS Synth Biol 2013, 2 (11), 629-634.

33. Yin, W.-B.; Baccile, J. A.; Bok, J. W.; Chen, Y.; Schroeder, F. C.;Keller, N. P.*, A nonribosomal peptide synthetase-derived iron(III) complex from the pathogenic fungus Aspergillus fumigatus. J Am Chem Soc 2013, 135 (6), 2064-2067.

32. Amaike, S.; Affeldt, K. J.; Yin, W.-B.; Franke, S.; Choithani, A.; Keller, N. P.*, The bZIP protein MeaB mediates virulence attributes in Aspergillus flavus. PLoS One 2013, 8 (9), e74030.

31. Yin, W.-B.; Amaike, S.; Wohlbach, D. J.; Gasch, A. P.; Chiang, Y. M.; Wang, C. C.; Bok, J. W.;  Rohlfs, M.; Keller, N. P.*, An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR. Mol Microbiol 2012, 83 (5), 1024-1034.

30. Yin, W.-B.; Keller, N. P.*, Transcriptional regulatory elements in fungal secondary metabolism. J Microbiol 2011, 49 (3), 329-339.

29. Yin, W.-B.; Yu, X.; Xie, X. L.; Li, S. M.*, Preparation of pyrrolo[2,3-b]indoles carrying a beta-configured reverse C3-dimethylallyl moiety by using a recombinant prenyltransferase CdpC3PT. Org Biomol Chem 2010, 8 (10), 2430-2438.

28. Yin, W.-B.; Xie, X. L.; Matuschek, M.; Li, S. M.*, Reconstruction of pyrrolo[2,3-b]indoles carrying an alpha-configured reverse C3-dimethylallyl moiety by using recombinant enzymes. Org Biomol Chem 2010, 8 (5), 1133-1141.

 

2006-2010年

 

27. Yin, W.-B.; Cheng, J.; Li, S. M.*, Stereospecific synthesis of aszonalenins by using two recombinant prenyltransferases. Org Biomol Chem 2009, 7 (10), 2202-2207.

26. Liu, X.; Wang, L.; Steffan, N.; Yin, W.-B.; Li, S. M.*, Ergot alkaloid biosynthesis in Aspergillus fumigatus: FgaAT catalyses the acetylation of fumigaclavine B. Chembiochem 2009, 10 (14), 2325-8.

25. Yin, W.-B.; Grundmann, A.; Cheng, J.; Li, S. M.*, Acetylaszonalenin biosynthesis in Neosartorya fischeri. Identification of the biosynthetic gene cluster by genomic mining and functional proof of the genes by biochemical investigation. J Biol Chem 2009, 284 (1), 100-109.

24. Steffan, N.; Grundmann, A.; Yin, W.-B.; Kremer, A.; Li, S. M.*, Indole prenyltransferases from fungi: a new enzyme group with high potential for the production of prenylated indole derivatives. Curr Med Chem 2009, 16 (2), 218-231.

23. Ruan, H. L.; Yin, W.-B.; Wu, J. Z.; Li, S. M.*, Reinvestigation of a cyclic dipeptide N-prenyltransferase reveals rearrangement of N-1 prenylated indole derivatives. Chembiochem 2008, 9 (7), 1044-7.

22. Yin, W.-B.; Ruan, H. L.; Westrich, L.; Grundmann, A.; Li, S. M.*, CdpNPT, an N-prenyltransferase from Aspergillus fumigatus: overproduction, purification and biochemical characterisation. Chembiochem 2007, 8 (10), 1154-61.

 

中文文章:

 

21. 黄润业,亓兰达,陈国参,尹文兵*, 免疫抑制剂霉酚酸的研究及产业化进展. 微生物学报 2021, 61 (6), 1-16.

20. 谢丽媛,尹文兵,李伟*,高伟*, 白僵菌天然产物及其药理活性和生物合成研究进展. 天然产物研究与开发 2021, 33 (01), 150-164.

19. 郭庆丰,陈林*,尹震花,张娟娟,王彦波尹文兵, 大黄鱼共生菌 Bacillus coagulans LL1103 的代谢产物研究. 微生物学报 2020, 60 (2), 387-396.

18. 蒲语涵,刘欢,陈国参,郭莉霞*尹文兵*, 炭团木霉中非核糖体多肽基因 NRPS1 的功能研究. 微生物学报 2020, 60 (9), 1–12.

17. 亓兰达,魏鹏霖,张晗星,陈国参,张英涛,尹文兵*, 后基因组时代害虫生防真菌次级代谢产物的 研究进展. 中国科学: 生命科学 2020, 50 (6), 589-598.

16. 宋自力,廖头根,张伟,陈国参,李伟*,汪世华*尹文兵*, 白腐真菌血红密孔菌漆酶复合酶预处理烟梗丝的响应面法优化. 菌物学报 2020, 39 (5), 923-936.

15. 徐新然,吕海宁,周爽,尹文兵*, 真菌次级代谢转录调控研究进展. 菌物研究 2019, 17 (3), 125-137.

14. 吴洪波,陈林,吕海宁,刘欢,汪世华*尹文兵*, 炭团木霉 Trichoderma hypoxylon 中一个新倍半萜. 菌物学报 2019, 38 (4), 533-538.

13. 魏鹏霖,张鹏,李伟*,汪世华*尹文兵, 黄曲霉分生孢子色素合成基因 pks1 的鉴定及其对生长发育和侵 染性的影响. 微生物学报 2019, 59 (5), 965-977.

12. 宋自力,张伟,廖头根,汪世华,李伟*尹文兵*, 血红密孔菌高产漆酶菌株的筛选及其对烟梗的生物降解. 菌物学报 2019, 38 (3), 381-392.

11. 郑艳静,王秀娜,章小灵,李伟,刘钢,汪世华,阎秀峰,邹慧熙*尹文兵*, COP9信号小体亚基CsnE对无花果拟盘多毛孢生长发育和次级代谢的影响. 中国科学: 生命科学 2017, 47 (7), 750-758.

10. 甄静,李冠杰,李伟,杜志敏,王继雯,尹文兵*,陈国参*, 毛栓孔菌XYG422菌株产漆酶发酵条件优化及对玉米秸秆生物 降解的研究. 菌物学报 2017, 36 (6), 718-729.

9. 马紫卉,李伟,尹文兵*, 真菌天然产物异源生产研究进展. 微生物学报 2016, 56 (3), 429-440.

8. 李伟,吴广畏,杨玉萍,尹文兵*, 后基因组时代的真菌天然产物发现. 菌物学报 2015, 34 (5), 914-926.

7. 王璐,尹文兵,李书明,刘晓晴*, 异戊烯基化吲哚类生物碱的化学酶合成. 中国生物化学与分子生物学报 2009, 25 (6), 580-584.

6. 尹文兵,李伟,周燕,李颖石,印莉萍,黄勤妮*, 大花红景天的组织培养和快速繁殖. 植物生理学通讯 2005, 41 (4), 493.

5. 尹文兵,李伟,杜桂森,黄勤妮*, 西藏红景天组织培养研究. 西北植物学报 2004, 24 (8), 1506-1510.

4. 尹文兵, 李丽娟, 黄勤妮, 李艳红, 胡萝卜愈伤组织的诱导及细胞悬浮培养研究. 山西师范大学学报(自然科学版) 2004, 18 (2), 71-76.

3. 尹文兵,黄勤妮,印莉萍*, 模式植物蛋白质组研究进展. 生物信息学 2003, 2 (2), 47-50.

2. 毕润成*,尹文兵,王艳妮, 山西南部脱皮榆种群生态位的研究. 西北植物学报 2003, 7, 210-215.

1. 尹文兵, 晋东南师专校园植物初步调查. 晋东南师范专科学校学报 2000, 3, 40-42.