2025年
140.Zhang, H. J.;Zhang, A. X.;Wen Y.;Ji, J, T. Yin, W. B. *, Catalytic Versatility of FnsA: Substrate-dependent Activity of KR and DH Domains in Naringenin Biosynthesis. J Agric Food Chem 2025, 73(33):20810-20817.
139. Zhang, Y. W.;Zong, J. F.;Liu, Y. F.;Zhou, K. Y.;Shi, H. B.; Yin, W. B. ,Liu L.,Chen, Y. H.*; Progress on targeted discovery of microbial natural products based on the predictions of both structure and activity. Nat Prod Rep.15;42(10):1651-1663.
138. Lin, S.;Zhang X. T.;Wang H.;Qiao Y. B.;Yu, J. W.;Peng Y.Y.;Wang C.Y.;Cao, F.; Yin, W. B. ,Chen, C. M.;Zhu, H.C.;Zhou Y.;Sun W. G.; Hu Z. X.;Ye Y.;Zhang Y.H.; Diasperonins A-F: Anti-inflammatory Aspertetronin Dimers Discovered via BBMN and Heterologous Expression Strategy. Org Lett,7(21):5435-5439.
137.Zhou S.; Li M.;Wang P.;Guo C.; Zhang J.; Luo X.; Fan Y. C.; Chen E. Q.;, Qi X.; Chen J.; Ye L.; Yuan H. Y.; Yin, W. B. ;Wang K.*;Zheng M. H.*; Pang Y*; Qiao J*; Jiang C.T.*; A symbiotic filamentous gut fungus ameliorates MASH via a secondary metabolite-CerS6-ceramide axis. Science,388(6746):eadp5540.
136. Ren Z.D.; Li Y. Y; Wei P. L.; Zhang S. Q.; Wang D; Fan J.; Yin, W. B. *, Novel Epidithiodiketopiperazine Derivatives in the Mutants of the Filamentous Fungus Trichoderma hypoxylon. J Fungi (Basel), 22;11(4):241.
135.Zhang S. Q.; Wei P. L.; Li Y. Y; Ren Z.D.; Fan J.; Yin, W. B. *, Functional diversification of epidithiodiketopiperazine methylation and oxidation towards pathogenic fungi. Mycology, 21;16(3):1418-1431.
134.Zhang A. X.; Xu X. R.; Yin, W. B. *, Genome Mining of Epicoccum dendrobii Reveals Diverse Antimicrobial Natural Products. J Agric Food Chem, 73(11):6691-6701
133. Zhang, A. X.; Zhang, S.;Xu, X. R.;Yin, W. B. *, Deletion of bZIP Transcription Factor PratfA Reveals Specialized Metabolites Potentially Regulating Stress Response in Penicillium raistrickii.J Fungi (Basel) 2024, 17;11(1):72.
2024年
132. Fan, J.; Wei, P. L.; Li, Y. Y; Zhang, S. Q.; Ren, Z. D. Li, W.;Yin, W. B. *, Developing filamentous fungal chassis for natural product production. Bioresour Technol 2024, 415:131703.
131. Xu, X. R.; Sun, Y. H.; Zhang, A. X.; Li, S. J.; Zhang, S.; Chen, S. J.; Lou, C. b.; Cai, L.; Chen, Y. H.; Luo, C. X. *; Yin, W. B. *, Quantitative Characterization of Gene Regulatory Circuits Associated With Fungal Secondary Metabolism to Discover Novel Natural Products. Adv Sci 2024, e2407195.
130. Zhang, S.; Shi, G. H.; Xu, X. R.; Guo, X.;Li, S. J.; Li, Z. Y.; Wu, Q. *; Yin, W. B. *,Global Analysis of Natural Products Biosynthetic Diversity Encoded in Fungal Genomes. J Fungi (Basel) 2024, 10(9):653.
129. Shen, X. R.; Lei, C. Z.; Zhang, A. X.; Wang, L.; Chen, D. H.; Qi, L. D.; Hu, Y. L.; Chen, G. C.;Ran, H. M.; Yin, W. B. *, Stimulating Novel and Bioactive Metabolite Production by Cocultivation of Two-Aspergillus oryzae and Epicoccum dendrobii. J Agric Food Chem 2024, 72(30):16825-16834.
128.Wang X, Zhou S, Hu X, Ye C, Nie Q, Wang K, Yan S, Lin J, Xu F, Li M, Wu Q, Sun L, Liu B, Zhang Y, Yun C, Wang X, Liu H, Yin,W. B., Zhao D, Hang J*, Zhang S*, Jiang C*, Pang Y*. Candida albicans Accelerates Atherosclerosis by Activating Intestinal Hypoxia-inducible Factor2α Signaling. Cell Host Microbe 2024 Jun 12;32(6):964-979.e7.
127.Ke W, Xie Y, Chen Y, Ding H, Ye L, Qiu H, Li H, Zhang L, Chen L, Tian X, Shen Z, Song Z, Fan X, Zong JF, Guo Z, Ma X, Xiao M, Liao G, Liu CH, Yin,W. B, Dong Z, Yang F, Jiang YY, Perlin DS, Chen Y, Fu YV*, Wang L*. Fungicide-tolerant Persister Formation during Cryptococcal Pulmonary Infection. Cell Host Microbe 2024 Feb 14;32(2):276-289.e7.
126.He R, Gu S, Xu J, Li X, Chen H, Shao Z, Wang F, Shao J, Yin W. B, Qian L, Wei Z*, Li Z. SIDERITE: Unveiling Hidden Siderophore Diversity in The Chemical Space through Digital Exploration. iMeta 2024 Apr 5;3(2):e192.
2023年
125. Fan, J.; Wei, P. L.; Yin, W. B. *, Formation of bridged disulfide in epidithiodioxopiperazines. Chembiochem: a European journal of chemical biology 2023, e202300770.
124. Song, Z.; Zhou, S.; Zhang, H.; Keller, N.P.; Oakley, B.R.; Liu, X.; Yin, W. B. *, Fungal secondary metabolism is governed by an RNA-binding protein CsdA/RsdA complex. Nat Commun 2023, 14, 7351.
123. Wang, P. *; Park, H.S.; Wang, W.; Yin, W. B. *, Editorial: Gene regulation of fungal secondary metabolism. Frontiers in microbiology 2023, 14, 1260849.
122. He, R.; Zhang, J.; Shao, Y.; Gu, S.; Song, C.; Qian, L.; Yin, W. B. *; Li, Z.*, Knowledge-guided data mining on the standardized architecture of NRPS: Subtypes, novel motifs, and sequence entanglements. PLoS Comput Biol 2023, 19 (5), e1011100.
121. Fan, J.; Ran, H.; Wei, P. L.; Li, Y.; Liu, H.; Li, S. M.; Yin, W. B. *, An ortho-Quinone Methide Mediates Disulfide Migration in the Biosynthesis of Epidithiodiketopiperazines. Angew Chem Int Ed Engl 2023, e202304252.
120. Fan, J.; Ran, H.; Wei, P. L.; Li, Y.; Liu, H.; Li, S. M.; Hu, Y.; Yin, W. B. *, Pretrichodermamide A Biosynthesis Reveals the Hidden Diversity of Epidithiodiketopiperazines. Angew Chem Int Ed Engl 2023, e202217212.
119. Liu, Z.; Li, W.; Zhang, P.; Sun, Y.*; Yin, W.-B.*, Heterologous production of bioactive xenoacremone analogs in Aspergillus nidulans. Chin J of Nat Medicines 2023, 21, 1-7.
118. Dai, H.; Han, J.; Wang, T.; Yin, W.-B.; Chen, Y.; Liu, H.*, Recent advances in gut microbiota-associated natural products: structures, bioactivities, and mechanisms. Nat Prod Rep 2023.
117. Feng, J.; Li, J.; Liu, D.; Xin, Y.; Sun, J.; Yin, W.-B.; Li, T.*, Generation and comprehensive analysis of Synechococcus elongatus–Aspergillus nidulans co-culture system for polyketide production. Biotechnol Biofuels Biopro 2023, 16 (1), 32.
2022年:
116. Zhang, H.; Li, Z.; Zhou, S.; Li, S. M.; Ran, H.; Song, Z.; Yu, T.; Yin, W. B. *, A fungal NRPS-PKS enzyme catalyses the formation of the flavonoid naringenin. Nat Commun 2022, 13 (1), 6361.
115. Wei, P. L.; Fan, J.; Yu, J.; Ma, Z.; Guo, X.; Keller, N. P.; Li, E.; Lou, C.; Yin, W. B. *, Quantitative characterization of filamentous fungal promoters on a single-cell resolution to discover cryptic natural products. Sci China Life Sci 2023, 66 (4), 848-860.
114. Yang, L.; Wu, G.; Meng, F.; Ran, H.; Yin, W.-B.; Li, W.; Liu, X., Combination strategy of genetic dereplication and manipulation of epigenetic regulators reveals a novel compound from plant endophytic fungus. Int J Mol Sci 2022, 23 (7).
113. Wang, G.; Ran, H.; Fan, J.; Keller, N.; Liu, Z.; Wu, F.; Yin, W.-B. *, Fungal-fungal cocultivation leads to widespread secondary metabolite alteration requiring the partial loss-of-function VeA1 protein. Sci adv 2022, 8, eabo6094.
112. Li, Y.; Wei, P. L.; Ran, H.; Fan, J. *; Yin, W. B. *, Characterization of a NRPS-like Protein from Pestalotiopsis fici for Aldehyde Generation. J Fungi (Basel) 2022, 8 (10).
111. Zhang, X.; Xu, D.; Hou, X.; Wei, P.; Fu, J.; Zhao, Z.; Jing, M.; Lai, D.; Yin, W. B. *; Zhou, L. *, UvSorA and UvSorB involved in sorbicillinoid biosynthesis contribute to fungal development, stress response and phytotoxicity in Ustilaginoidea virens. Int J Mol Sci 2022, 23 (19).
110. Han, J.; Baosong, C.; Zhang, R.; Zhang, J.; Huanqin, D.; Wang, T.; Sun, J.; Zhu, G.; Li, W.; Li, E.; Liu, X.; Yin, W.-B.; Liu, H.*, Exploring verrucosidin derivatives with glucose-uptake-stimulatory activity from Penicillium cellarum using MS/MS-based molecular networking. J Fungi (Basel) 2022, 8, 143.
109. Zhang, Z. X.; Li, Z. H.; Yin, W.-B.; Li, S. M.*, Biosynthesis of viridicatol in Penicillium palitans implies a cytochrome P450-mediated meta hydroxylation at a monoalkylated benzene ring. Org Lett 2022, 24 (1), 262-267.
2021年:
108. Zhang, J. Y.; Qi, L. D.; Chen, G. C.; Yin, W.-B.*, Discovery and genetic identification of amphiphilic coprogen siderophores from Trichoderm hypoxylon. Appl Microbiol Biot 2021.
107. Zhang, J.; Zhang, P.; Zeng, G.; Wu, G.; Qi, L.; Chen, G.; Fang, W.; Yin, W.-B. *, Transcriptional differences guided discovery and genetic identification of coprogen and dimerumic acid siderophores in Metarhizium robertsii. Front Microbiol 2021, 12, 783609.
106. Zhang, J.; Yin, W.-B.*, Characterisation of two unique sesquiterpenoids from Trichoderma hypoxylon. Mycology 2021, 1-7.
105. Xu, X.; Huang, R.; Yin, W.-B.*, An optimized and efficient CRISPR/Cas9 system for the endophytic fungus Pestalotiopsis fici. J Fungi (Basel) 2021, 7 (10).
104. Xu, X.; Feng, J.; Zhang, P.; Fan, J.; Yin, W.-B. *, A CRISPR/Cas9 cleavage system for capturing fungal secondary metabolite gene clusters. J Microbiol Biotechn 2021, 31 (1), 8-15.
103. Song, Z.; Zhao, R.; Zhang, H.; Wei, P.; Qi, L.; Chen, G.; Yin, W.-B. *; Li, W. *, Rapid and accurate screening of lysine-producing edible mushrooms via the homocitrate synthase gene as a universal molecular marker. ACS Omega 2021, 6 (41), 26910-26918.
102. Song, Z.; He, M.; Zhao, R.; Qi, L.; Chen, G.; Yin, W.-B. *; Li, W. *, Molecular evolution of lysine biosynthesis in Agaricomycetes. J Fungi (Basel) 2021, 8 (1).
101. Ma, K.; Zhang, Y. T.; Guo, C.; Yang, Y. L.; Han, J. J.; Yu, B.; Yin, W.-B.; Liu, H. W.*, Reconstitution of biosynthetic pathway for mushroom-derived cyathane diterpenes in yeast and generation of new "non-natural" analogues. Acta Pharm Sin B 2021, 11 (9), 2945-2956.
100. Lyu, H. N.; Zhang, J.; Zhou, S.; Liu, H. W.; Zhuang, W. Y.; Li, S. M.; Yin, W.-B.*, Heterologous expression of a single fungal HR-PKS leads to the formation of diverse 2-alkenyl-tetrahydropyrans in model fungi. Org Biomol Chem 2021, 19 (38), 8377-8383.
99. Liu, Z. G.; Li, W.; Zhang, P.; Fan, J.; Zhang, F. B.; Wang, C. X.; Li, S. M.; Sun, Y.; Chen, S. L. *; Yin, W.-B.*, Tricarbocyclic core formation of tyrosine-decahydrofluorenes implies a three-enzyme cascade with XenF-mediated sigmatropic rearrangement as a prerequisite. Acta Pharm Sin B 2021, 11 (11), 3655-3664.
98. Liu, H.; Fan, J.; Zhang, P.; Hu, Y. C.; Liu, X. Z.; Li, S. M. *; Yin, W.-B.*, New insights into the disulfide bond formation enzymes in epidithiodiketopiperazine alkaloids. Chem Sci 2021, 12 (11), 4132-4138.
97. Liang, M.; Lyu, H. N.; Ma, Z. Y.; Li, E. W.; Cai, L. *; Yin, W.-B.*, Genomics-driven discovery of a new cyclodepsipeptide from the guanophilic fungus Amphichorda guana. Org Biomol Chem 2021, 19 (9), 1960-1964.
96. Liang, M.; Li, W.; Qi, L.; Chen, G.; Cai, L.; Yin, W.-B.*, Establishment of a genetic transformation system in guanophilic fungus Amphichorda guana. J Fungi (Basel) 2021, 7 (2).
95. Li, W.; Fan, J.; Liao, G.; Yin, W.-B.; Li, S. M.*, Precursor supply increases the accumulation of 4-hydroxy-6-(4-hydroxyphenyl)-alpha-pyrone after NRPS-PKS gene expression. J Nat Prod 2021.
94. Hou, B.; Liu, S.; Huo, R.; Li, Y.; Ren, J.; Wang, W.; Wei, T.; Jiang, X.; Yin, W.-B.; Liu, H.; Liu, L.*; Li, E.*, New diterpenoids and isocoumarin derivatives from the mangrove-derived fungus Hypoxylon sp. Mar Drugs 2021, 19 (7).
93. Guo, Q. F.; Chen, J. H.; Ren, Y. W.; Yin, Z. H.; Zhang, J. J.; Yang, B. C.; Wang, X. W.; Yin, W.-B.; Zhang, W. C. *; Ding, G. *; Chen, L. *, Hydrazine-containing heterocycle cytochalasan derivatives from hydrazinolysis of extracts of a desert soil-derived fungus Chaetomium madrasense 375. Front Chem 2021, 9.
92. Bakany, B.; Yin, W.-B.; Dienes, B.; Nagy, T.; Leiter, E.; Emri, T.; Keller, N. P. *; Pocsi, I. *, Study on the bZIP-type transcription factors NapA and RsmA in the regulation of intracellular reactive species levels and sterigmatocystin production of Aspergillus nidulans. Int J Mol Sci 2021, 22 (21).
2020年:
91. Xiang, P.; Ludwig-Radtke, L.; Yin, W.-B.; Li, S. M. *, Isocoumarin formation by heterologous gene expression and modification by host enzymes. Org Biomol Chem 2020, 18 (26), 4946-4948.
90. Nies, J.; Ran, H.; Wohlgemuth, V.; Yin, W.-B.; Li, S. M.*, Biosynthesis of the prenylated salicylaldehyde flavoglaucin requires temporary reduction to salicyl alcohol for decoration before reoxidation to the final product. Org Lett 2020, 22 (6), 2256-2260.
89. Lyu, H. N.; Liu, H. W.; Keller, N. P.; Yin, W.-B.*, Harnessing diverse transcriptional regulators for natural product discovery in fungi. Nat Prod Rep 2020, 37 (1), 6-16.
88. Liu, H.; Pu, Y. H.; Ren, J. W.; Li, E. W.; Guo, L. X.; Yin, W.-B.*, Genetic dereplication driven discovery of a tricinoloniol acid biosynthetic pathway in Trichoderma hypoxylon. Org Biomol Chem 2020, 18 (28), 5344-5348.
87. Fan, J.; Liao, G.; Ludwig-Radtke, L.; Yin, W.-B.; Li, S. M.*, Formation of terrestric acid in Penicillium crustosum requires redox-assisted decarboxylation and stereoisomerization. Org Lett 2020, 22 (1), 88-92.
2019年:
86. Zhou, S.; Zhang, P.; Zhou, H.; Liu, X.; Li, S. M.; Guo, L.; Li, K.; Yin, W.-B.*, A new regulator RsdA mediating fungal secondary metabolism has a detrimental impact on asexual development in Pestalotiopsis fici. Environ Microbiol 2019, 21 (1), 416-426.
85. Zhang, P.; Zhou, S.; Wang, G.; An, Z.; Liu, X.; Li, K.; Yin, W.-B.*, Two transcription factors cooperatively regulate DHN melanin biosynthesis and development in Pestalotiopsis fici. Mol Microbiol 2019, 112 (2), 649-666.
84. Wang, J.; Zhang, Y.; Liu, H.; Shang, Y.; Zhou, L.; Wei, P.; Yin, W.-B.; Deng, Z.; Qu, X. *; Zhou, Q.*, A biocatalytic hydroxylation-enabled unified approach to C19-hydroxylated steroids. Nat Commun 2019, 10 (1), 3378.
83. Ma, K.; Zhang, P.; Tao, Q.; Keller, N. P.; Yang, Y.; Yin, W.-B.*; Liu, H. *, Characterization and biosynthesis of a rare fungal hopane-type triterpenoid glycoside involved in the antistress property of Aspergillus fumigatus. Org Lett 2019, 21 (9), 3252-3256.
82. Li, W.; Yu, J.; Li, Z.; Yin, W.-B. *, Rational design for fungal laccase production in the model host Aspergillus nidulans. Sci China Life Sci 2019, 62 (1), 84-94.
81. Li, W.; Yin, W.-B.*, Genetic mining of the "dark matter" in fungal natural products. Sci China Life Sci 2019, 62 (9), 1250-1252.
80. Li, R.; Li, Z.; Ma, K.; Wang, G.; Li, W.; Liu, H. W.; Yin, W.-B.*; Zhang, P. *; Liu, X. Z. *, Strategy for efficient cloning of biosynthetic gene clusters from fungi. Sci China Life Sci 2019, 62 (8), 1087-1095.
79. Fan, J.; Liao, G.; Kindinger, F.; Ludwig-Radtke, L.; Yin, W.-B.; Li, S. M. *, Peniphenone and penilactone formation in Penicillium crustosum via 1,4-Michael additions of ortho-quinone methide from hydroxyclavatol to gamma-butyrolactones from crustosic acid. J Am Chem Soc 2019, 141 (10), 4225-4229.
78. Chen, L.; Wu, H.; Liu, H.; Li, E.; Ren, J.; Wang, W.; Wang, S.; Yin, W.-B.*, Genetic dereplication of Trichoderma hypoxylon reveals two novel polycyclic lactones. J Asian Nat Prod Res 2019, 91, 103185.
77. Chen, L.; Wu, G. W.; Liu, D.; Zhuang, W. Y.; Yin, W.-B.*, Trichodermatides E and F from fungus Trichoderma applanatum. J Asian Nat Prod Res 2019, 21 (7), 659-665.
2018年:
76. Zeng, G.; Zhang, P.; Zhang, Q.; Zhao, H.; Li, Z.; Zhang, X.; Wang, C.; Yin, W.-B.; Fang, W.*, Duplication of a Pks gene cluster and subsequent functional diversification facilitate environmental adaptation in Metarhizium species. PLoS Genet 2018, 14 (6), e1007472.
75. Wang, Y.; Wang, L.; Wu, F.; Liu, F.; Wang, Q.; Zhang, X.; Selvaraj, J. N.; Zhao, Y.; Xing, F.; Yin, W.-B.; Liu, Y.*, A consensus ochratoxin A biosynthetic pathway: insights from the genome sequence of Aspergillus ochraceus and a comparative genomic analysis. Appl Environ Microbiol 2018, 84 (19).
74. Wang, S. S.; Cui, H.; Ye, J.; Wu, Y.; Wang, S. X.; Yin, W.-B.*, Identification and determination of rubrofusarin, rubrofusarin isomer, and their quinone forms in grains using high-resolution mass spectrometry. ACS Omega 2018, 3 (11), 15924-15932.
73. Ma, Z.; Li, W.; Zhang, P.; Lyu, H.; Hu, Y.; Yin, W.-B.*, Rational design for heterologous production of aurovertin-type compounds in Aspergillus nidulans. Appl Environ Microbiol 2018, 102 (1), 297-304.
72. Liu, Z. G.; Bao, L.; Liu, H. W.; Ren, J. W.; Wang, W. Z.; Wang, L.; Li, W.; Yin, W.-B.*, Chemical diversity from the Tibetan Plateau fungi Penicillium kongii and P. brasilianum. Mycology 2018, 9 (1), 10-19.
71. Liu, L.; Bao, L.; Wang, L.; Ma, K.; Han, J. J.; Yang, Y. L.; Liu, R. X.; Ren, J. W.; Yin, W.-B.; Wang, W. Z.; Liu, H. W.*, Asperorydines A-M: prenylated tryptophan-derived alkaloids with neurotrophic effects from Aspergillus oryzae. J Org Chem 2018, 83 (2), 812-822.
70. Yang, Y.; Zhang, Y.; Zhang, S.; Chen, Q.; Ma, K.; Bao, L.; Tao, Y.; Yin, W.-B.; Wang, G.; Liu, H., Identification and characterization of a membrane-bound sesterterpene cyclase from Streptomyces somaliensis. J Nat Prod 2018, 81 (4), 1089-1092.
69. Liu, H.; Wang, G.; Li, W.; Liu, X.; Li, E.; Yin, W.-B.*, A highly efficient genetic system for the identification of a harzianum B biosynthetic gene cluster in Trichoderma hypoxylon. Microbiology 2018, 164 (5), 769-778.
68. Lin, H.; Lyu, H.; Zhou, S.; Yu, J.; Keller, N. P.; Chen, L.; Yin, W.-B.*, Deletion of a global regulator LaeB leads to the discovery of novel polyketides in Aspergillus nidulans. Org Biomol Chem 2018, 16 (27), 4973-4976.
67. Li, W.; Ma, Z.; Chen, L.; Yin, W.-B.*, Synthesis and production of the antitumor polyketide aurovertins and structurally related compounds. Appl Environ Microbiol 2018, 102 (15), 6373-6381.
66. Li, W.; Fan, A.; Wang, L.; Zhang, P.; Liu, Z.; An, Z.; Yin, W.-B.*, Asperphenamate biosynthesis reveals a novel two-module NRPS system to synthesize amino acid esters in fungi. Chem Sci 2018, 9 (9), 2589-2594.
2017年:
65. Zheng, Y.; Wang, X.; Zhang, X.; Li, W.; Liu, G.; Wang, S.; Yan, X.; Zou, H.*; Yin, W.-B.*, COP9 signalosome subunit PfCsnE regulates secondary metabolism and conidial formation in Pestalotiopsis fici. Sci China Life Sci 2017, 60 (6), 656-664.
64. Zheng, Y.; Ma, K.; Lyu, H.; Huang, Y.; Liu, H.; Liu, L.; Che, Y.; Liu, X.; Zou, H.; Yin, W.-B.*, Genetic manipulation of the COP9 signalosome subunit PfCsnE leads to the discovery of pestaloficins in Pestalotiopsis fici. Org Lett 2017, 19 (17), 4700-4703.
63. Zhao, W.; Fan, A.; Tarcz, S.; Zhou, K.; Yin, W.-B.; Liu, X. Q.*; Li, S. M.*, Mutation on Gly115 and Tyr205 of the cyclic dipeptide C2-prenyltransferase FtmPT1 increases its catalytic activity toward hydroxynaphthalenes. Appl Microbiol Biot 2017, 101 (5), 1989-1998.
62. Zhang, P.; Wang, X.; Fan, A.; Zheng, Y.; Liu, X.; Wang, S.; Zou, H.; Oakley, B. R.; Keller, N. P.; Yin, W.-B.*, A cryptic pigment biosynthetic pathway uncovered by heterologous expression is essential for conidial development in Pestalotiopsis fici. Mol Microbiol 2017, 105 (3), 469-483.
61. Yang, Y. L.; Zhang, S.; Ma, K.; Xu, Y.; Tao, Q.; Chen, Y.; Chen, J.; Guo, S.; Ren, J.; Wang, W.; Tao, Y.; Yin, W.-B.; Liu, H.*, Discovery and characterization of a new family of diterpene cyclases in bacteria and fungi. Angew Chem Int Ed 2017, 56 (17), 4749-4752.
60. Liu, L.; Wang, L.; Bao, L.; Ren, J.; Bahadur B., B.; Liu, R.; He, L.; Han, J.; Yin, W.-B.; Liu, H. W.*, Versicoamides F-H, prenylated indole alkaloids from Aspergillus tennesseensis. Org Lett 2017, 19 (4), 942-945.
59. Han, J.; Liu, C.; Li, L.; Zhou, H.; Liu, L.; Bao, L.; Chen, Q.; Song, F.; Zhang, L.; Li, E.; Liu, L.; Pei, Y.; Jin, C.; Xue, Y.; Yin, W.-B.; Ma, Y.; Liu, H. W.*, Decalin-containing tetramic acids and 4-hydroxy-2-pyridones with antimicrobial and cytotoxic activity from the fungus Coniochaeta cephalothecoides collected in Tibetan Plateau (Medog). J Org Chem 2017, 82 (21), 11474-11486.
58. Feng, J.; Zhang, P.; Cui, Y. L.; Li, K.; Qiao, X.; Zhang, Y. T.; Li, S. M.; Cox, R. J.; Wu, B.; Ye, M.*; Yin, W.-B.*, Regio- and stereospecific O-glycosylation of phenolic compounds catalyzed by a fungal glycosyltransferase from Mucor hiemalis. Adv Synth Catal 2017, 359 (6), 995-1006.
57. Fan, A.; Mi, W.; Liu, Z.; Zeng, G.; Zhang, P.; Hu, Y.; Fang, W.; Yin, W.-B.*, Deletion of a histone acetyltransferase leads to the pleiotropic activation of natural products in Metarhizium robertsii. Org Lett 2017, 19 (7), 1686-1689.
2016年:
56. Han, X.; Qiu, M.; Wang, B.; Yin, W.-B.; Nie, X.; Qin, Q.; Ren, S.; Yang, K.; Zhang, F.; Zhuang, Z.; Wang, S.*, Functional analysis of the nitrogen metabolite repression regulator gene nmrA in Aspergillus flavus. Front Microbiol 2016, 7, 1794.
55. Sun, J.; Pei, Y.; Li, E.; Li, W.; Hyde, K. D.; Yin, W.-B.*; Liu, X.*, A new species of Trichoderma hypoxylon harbours abundant secondary metabolites. Sci Rep 2016, 6, 37369.
54. Tao, Q.; Ma, K.; Yang, Y.; Wang, K.; Chen, B.; Huang, Y.; Han, J.; Bao, L.; Liu, X. B.; Yang, Z.; Yin, W.-B.; Liu, H.*, Bioactive sesquiterpenes from the edible mushroom Flammulina velutipes and their biosynthetic pathway confirmed by genome analysis and chemical evidence. J Org Chem 2016, 81 (20), 9867-9877.
53. Wang, G.; Liu, Z.; Lin, R.; Li, E.; Mao, Z.; Ling, J.; Yang, Y.; Yin, W.-B.*; Xie, B.*, Biosynthesis of antibiotic leucinostatins in bio-control fungus Purpureocillium lilacinum and their inhibition on Phytophthora revealed by genome mining. PLoS Pathog 2016, 12 (7), e1005685.
52. Wang, K.; Bao, L.; Ma, K.; Qi, W.; Song, F.; Yao, Y.; Yin, W.-B.; Zhang, L.; Huang, Y.; Han, J.; Liu, H.*, Bioactive spirobisnaphthalenes and lactones from a cup fungus Plectania sp. collected in the Tibet Plateau region. Eur J Org Chem 2016, 2016 (25), 4338-4346.
51. Wu, G.; Zhou, H.; Zhang, P.; Wang, X.; Li, W.; Zhang, W.; Liu, X.; Liu, H. W.; Keller, N. P.; An, Z.; Yin, W.-B.*, Polyketide production of pestaloficiols and macrodiolide ficiolides revealed by manipulations of epigenetic regulators in an endophytic fungus. Org Lett 2016, 18 (8), 1832-1835.
2015年:
50. Wang, X.; Zhang, X.; Liu, L.; Xiang, M.; Wang, W.; Sun, X.; Che, Y.; Guo, L.; Liu, G.; Guo, L.; Wang, C.; Yin, W.-B.; Stadler, M.; Zhang, X.*; Liu, X.*, Genomic and transcriptomic analysis of the endophytic fungus Pestalotiopsis fici reveals its lifestyle and high potential for synthesis of natural products. BMC Genomics 2015, 16, 28.
49. Wang, X.; Wu, F.; Liu, L.; Liu, X.; Che, Y.; Keller, N. P.; Guo, L.*; Yin, W.-B.*, The bZIP transcription factor PfZipA regulates secondary metabolism and oxidative stress response in the plant endophytic fungus Pestalotiopsis fici. Fungal Genet Biol 2015, 81, 221-228.
48. Wang, L.; Feng, Y.; Tian, J.; Xiang, M.; Sun, J.; Ding, J.; Yin, W.-B.; Stadler, M.; Che, Y.; Liu, X.*, Farming of a defensive fungal mutualist by an attelabid weevil. ISME J 2015, 9 (8), 1793-1801.
47. Wang, K.; Bao, L.; Xiong, W.; Ma, K.; Han, J.; Wang, W.; Yin, W.-B.; Liu, H.*, Lanostane triterpenes from the tibetan medicinal mushroom Ganoderma leucocontextum and their inhibitory effects on HMG-CoA reductase and alpha-glucosidase. J Nat Prod 2015, 78 (8), 1977-1989.
46. Wang, C.*; Lu, L.*; Yin, W.-B.*; Zhang, K. Q.*, From taxonomy and industry to genetics: fungal biology in China. Fungal Genet Biol 2015, 81, 110-112.
45. Qi, Q. Y.; Ren, J. W.; Sun, L. W.; He, L. W.; Bao, L.; Yue, W.; Sun, Q. M.; Yao, Y. J.; Yin, W.-B.; Liu, H. W.*, Stucturally diverse sesquiterpenes produced by a Chinese Tibet fungus Stereum hirsutum and their cytotoxic and immunosuppressant activities. Org Lett 2015, 17 (12), 3098-3101.
44. Mao, X. M.; Zhan, Z. J.; Grayson, M. N.; Tang, M. C.; Xu, W.; Li, Y. Q.; Yin, W.-B.; Lin, H. C.; Chooi, Y. H.; Houk, K. N.; Tang, Y.*, Efficient biosynthesis of fungal polyketides containing the dioxabicyclo-octane ring system. J Am Chem Soc 2015, 137 (37), 11904-11907.
43. Mao, X. M.; Xu, W.; Li, D.; Yin, W.-B.; Chooi, Y. H.; Li, Y. Q.; Tang, Y.*; Hu, Y.*, Epigenetic genome mining of an endophytic fungus leads to the pleiotropic biosynthesis of natural products. Angew Chem Int Ed 2015, 54 (26), 7592-7596.
42. Han, J. J.; Bao, L.; Tao, Q. Q.; Yao, Y. J.; Liu, X. Z.; Yin, W.-B.; Liu, H. W.*, Gloeophyllins A-J, cytotoxic ergosteroids with various skeletons from a Chinese Tibet fungus Gloeophyllum abietinum. Org Lett 2015, 17 (10), 2538-2541.
2010-2014年:
41. Wiemann, P.; Lechner, B. E.; Baccile, J. A.; Velk, T. A.; Yin, W.-B.; Bok, J. W.; Pakala, S.; Losada, L.; Nierman, W. C.; Schroeder, F. C.; Haas, H.; Keller, N. P.*, Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus. Front Microbiol 2014, 5, 530.
40. Hu, Y.; Dietrich, D.; Xu, W.; Patel, A.; Thuss, J. A.; Wang, J.; Yin, W.-B.; Qiao, K.; Houk, K. N.; Vederas, J. C.*; Tang, Y.*, A carbonate-forming Baeyer-Villiger monooxygenase. Nat Chem Biol 2014, 10 (7), 552-554.
39. Yin, W.-B.; Reinke, A. W.; Szilagyi, M.; Emri, T.; Chiang, Y. M.; Keating, A. E.; Pocsi, I.; Wang, C. C.; Keller, N. P.*, bZIP transcription factors affecting secondary metabolism, sexual development and stress responses in Aspergillus nidulans. Microbiology 2013, 159 (Pt 1), 77-88.
38. Yin, W.-B.; Chooi, Y. H.; Smith, A. R.; Cacho, R. A.; Hu, Y.; White, T. C.; Tang, Y.*, Discovery of cryptic polyketide metabolites from dermatophytes using heterologous expression in Aspergillus nidulans. ACS Synth Biol 2013, 2 (11), 629-634.
37. Yin, W.-B.; Baccile, J. A.; Bok, J. W.; Chen, Y.; Schroeder, F. C.;Keller, N. P.*, A nonribosomal peptide synthetase-derived iron(III) complex from the pathogenic fungus Aspergillus fumigatus. J Am Chem Soc 2013, 135 (6), 2064-2067.
36. Amaike, S.; Affeldt, K. J.; Yin, W.-B.; Franke, S.; Choithani, A.; Keller, N. P.*, The bZIP protein MeaB mediates virulence attributes in Aspergillus flavus. PLoS One 2013, 8 (9), e74030.
35. Yin, W.-B.; Amaike, S.; Wohlbach, D. J.; Gasch, A. P.; Chiang, Y. M.; Wang, C. C.; Bok, J. W.; Rohlfs, M.; Keller, N. P.*, An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR. Mol Microbiol 2012, 83 (5), 1024-1034.
34. Yin, W.-B.; Keller, N. P.*, Transcriptional regulatory elements in fungal secondary metabolism. J Microbiol 2011, 49 (3), 329-339.
33. Yin, W.-B.; Yu, X.; Xie, X. L.; Li, S. M.*, Preparation of pyrrolo[2,3-b]indoles carrying a beta-configured reverse C3-dimethylallyl moiety by using a recombinant prenyltransferase CdpC3PT. Org Biomol Chem 2010, 8 (10), 2430-2438.
32. Yin, W.-B.; Xie, X. L.; Matuschek, M.; Li, S. M.*, Reconstruction of pyrrolo[2,3-b]indoles carrying an alpha-configured reverse C3-dimethylallyl moiety by using recombinant enzymes. Org Biomol Chem 2010, 8 (5), 1133-1141.
2006-2010年:
31. Yin, W.-B.; Cheng, J.; Li, S. M.*, Stereospecific synthesis of aszonalenins by using two recombinant prenyltransferases. Org Biomol Chem 2009, 7 (10), 2202-2207.
30. Liu, X.; Wang, L.; Steffan, N.; Yin, W.-B.; Li, S. M.*, Ergot alkaloid biosynthesis in Aspergillus fumigatus: FgaAT catalyses the acetylation of fumigaclavine B. Chembiochem 2009, 10 (14), 2325-8.
29. Yin, W.-B.; Grundmann, A.; Cheng, J.; Li, S. M.*, Acetylaszonalenin biosynthesis in Neosartorya fischeri. Identification of the biosynthetic gene cluster by genomic mining and functional proof of the genes by biochemical investigation. J Biol Chem 2009, 284 (1), 100-109.
28. Steffan, N.; Grundmann, A.; Yin, W.-B.; Kremer, A.; Li, S. M.*, Indole prenyltransferases from fungi: a new enzyme group with high potential for the production of prenylated indole derivatives. Curr Med Chem 2009, 16 (2), 218-231.
27. Ruan, H. L.; Yin, W.-B.; Wu, J. Z.; Li, S. M.*, Reinvestigation of a cyclic dipeptide N-prenyltransferase reveals rearrangement of N-1 prenylated indole derivatives. Chembiochem 2008, 9 (7), 1044-7.
26. Yin, W.-B.; Ruan, H. L.; Westrich, L.; Grundmann, A.; Li, S. M.*, CdpNPT, an N-prenyltransferase from Aspergillus fumigatus: overproduction, purification and biochemical characterisation. Chembiochem 2007, 8 (10), 1154-61.
中文文章:
30. 季佳童,张宏娇,尹文兵*.植物糖基转移酶的功能表征及类黄酮糖苷的微生物生产[J].微生物学报,2025,65(08):3671-3685.
29. 李思嘉,张安心,徐新然,尹文兵*.绿僵菌素的异源生物合成[J].中国抗生素杂志,2025,50(09):1116-1123.
28. 雷雨欣,宋自力,王东*,尹文兵*.钙调蛋白激酶转录抑制剂calmidazolium chloride抗烟曲霉及广谱活性研究[J].菌物学报,2025,44(08):119-131.
27. 吴佳雯,张盛权,尹文兵*.植物内生真菌生产紫杉醇:挑战与机遇[J].菌物研究,2025,23(02):79-92+76
26. 张宗源,岳丹丹,周留柱,王雪妍,陈登辉,潘梦诗,徐宏光,李冠杰,尹文兵*.产细菌素乳 酸菌 Lpe59 的选育及其细菌素基因簇的挖掘[J/OL].生物学杂志 2024,12-13.
25. 张姝,陈登辉,陈国参,徐新然*,尹文兵*.非模式真菌雷斯青霉遗传操作系统的建立[J]. 菌物学报 2024,43(06):92-101.
24. 冉火苗,尹文兵*. 基于微生物互作的新天然产物发掘研究进展. 药学进展 2023, 47, 260-272.
23. 杨会敏,李伟,汪世华*,尹文兵*. 耐低温玉米秸秆高效腐解真菌菌株的筛选及评价. 菌物研究 2023, 1-12.
22. 宋自力,李慧钰,王俊茹,米生权,李伟,尹文兵*, 大型真菌中谷氨酸生产菌的快速筛选. 微生物学通报 2022, 49 (10), 13.
21. 黄润业,亓兰达,陈国参,尹文兵*, 免疫抑制剂霉酚酸的研究及产业化进展. 微生物学报 2021, 61 (6), 1-16.
20. 谢丽媛,尹文兵,李伟*,高伟*, 白僵菌天然产物及其药理活性和生物合成研究进展. 天然产物研究与开发 2021, 33 (01), 150-164.
19. 郭庆丰,陈林*,尹震花,张娟娟,王彦波,尹文兵, 大黄鱼共生菌 Bacillus coagulans LL1103 的代谢产物研究. 微生物学报 2020, 60 (2), 387-396.
18. 蒲语涵,刘欢,陈国参,郭莉霞*,尹文兵*, 炭团木霉中非核糖体多肽基因 NRPS1 的功能研究. 微生物学报 2020, 60 (9), 1–12.
17. 亓兰达,魏鹏霖,张晗星,陈国参,张英涛,尹文兵*, 后基因组时代害虫生防真菌次级代谢产物的 研究进展. 中国科学: 生命科学 2020, 50 (6), 589-598.
16. 宋自力,廖头根,张伟,陈国参,李伟*,汪世华*,尹文兵*, 白腐真菌血红密孔菌漆酶复合酶预处理烟梗丝的响应面法优化. 菌物学报 2020, 39 (5), 923-936.
15. 徐新然,吕海宁,周爽,尹文兵*, 真菌次级代谢转录调控研究进展. 菌物研究 2019, 17 (3), 125-137.
14. 吴洪波,陈林,吕海宁,刘欢,汪世华*,尹文兵*, 炭团木霉 Trichoderma hypoxylon 中一个新倍半萜. 菌物学报 2019, 38 (4), 533-538.
13. 魏鹏霖,张鹏,李伟*,汪世华*,尹文兵, 黄曲霉分生孢子色素合成基因 pks1 的鉴定及其对生长发育和侵 染性的影响. 微生物学报 2019, 59 (5), 965-977.
12. 宋自力,张伟,廖头根,汪世华,李伟*,尹文兵*, 血红密孔菌高产漆酶菌株的筛选及其对烟梗的生物降解. 菌物学报 2019, 38 (3), 381-392.
11. 郑艳静,王秀娜,章小灵,李伟,刘钢,汪世华,阎秀峰,邹慧熙*,尹文兵*, COP9信号小体亚基CsnE对无花果拟盘多毛孢生长发育和次级代谢的影响. 中国科学: 生命科学 2017, 47 (7), 750-758.
10. 甄静,李冠杰,李伟,杜志敏,王继雯,尹文兵*,陈国参*, 毛栓孔菌XYG422菌株产漆酶发酵条件优化及对玉米秸秆生物 降解的研究. 菌物学报 2017, 36 (6), 718-729.
9. 马紫卉,李伟,尹文兵*, 真菌天然产物异源生产研究进展. 微生物学报 2016, 56 (3), 429-440.
8. 李伟,吴广畏,杨玉萍,尹文兵*, 后基因组时代的真菌天然产物发现. 菌物学报 2015, 34 (5), 914-926.
7. 王璐,尹文兵,李书明,刘晓晴*, 异戊烯基化吲哚类生物碱的化学酶合成. 中国生物化学与分子生物学报 2009, 25 (6), 580-584.
6. 尹文兵,李伟,周燕,李颖石,印莉萍,黄勤妮*, 大花红景天的组织培养和快速繁殖. 植物生理学通讯 2005, 41 (4), 493.
5. 尹文兵,李伟,杜桂森,黄勤妮*, 西藏红景天组织培养研究. 西北植物学报 2004, 24 (8), 1506-1510.
4. 尹文兵, 李丽娟., 黄勤妮, 李艳红, 胡萝卜愈伤组织的诱导及细胞悬浮培养研究. 山西师范大学学报(自然科学版) 2004, 18 (2), 71-76.
3. 尹文兵,黄勤妮,印莉萍*, 模式植物蛋白质组研究进展. 生物信息学 2003, 2 (2), 47-50.
2. 毕润成*,尹文兵,王艳妮, 山西南部脱皮榆种群生态位的研究. 西北植物学报 2003, 7, 210-215.
1. 尹文兵, 晋东南师专校园植物初步调查. 晋东南师范专科学校学报 2000, 3, 40-42.