华东理工大学特聘副研究员，硕士生导师。广东药科大学学士，华东理工大学博士及博后，主要研究方向为手性配体的设计合成及不对称催化新方法的创制。目前已在Nat. Chem., Nat. Synth., Nat. Commun., J. Am. Chem. Soc., Angew. Chem. Int. Ed.等期刊发表学术论文20余篇，受邀撰写综述论文1篇和书刊章节1章。主持博士后面上项目、博士后特别资助（站中），并作为研究骨干参与国家自然科学基金重大研究计划集成项目及科技部重大项目等。入选 “上海市超级博后”激励计划以及扬帆计划人才项目。
联系方式：xianqingwu@ecust.edu.cn
发表文章:
1. Wu, X.; Xia, H.; Gao, C.; Luan, B.; Wu, L.; Zhang, C.; Yang, D.; Hou, L.; Liu, N.; Xia, T.; Li, H.; Qu, J.; Chen, Y.* Modular α-tertiary amino ester synthesis through cobalt-catalysed asymmetric aza-Barbier reaction. Nat. Chem. 2024, 16, 398.
2. Wu, X.; Li, X.; Huang, W.; Wang, Y.; Xu, H.; Cai, L.; Qu, J.*; Chen, Y.* Direct Transformation of Aryl-2-Pyridyl Esters to Secondary Benzylic Alcohols by Nickel Relay Catalysis. Org. Lett. 2019, 21, 2453.
3. Wu, X.; Tang, Z.; Zhang, C.; Wang, C.; Wu, L.; Qu, J.*; Chen, Y.* Pd-Catalyzed Regiodivergent Synthesis of Diverse Oxindoles Enabled by the Versatile Heck Reaction of Carbamoyl Chlorides. Org. Lett. 2020, 22, 3915.
4. Wu, X.; Qu, J.*; Chen, Y.* Quinim: a New Ligand Enabled Nickel-Catalyzed Enantioselective Synthesis of α-Alkylated γ-Lactam. J. Am. Chem. Soc. 2020, 142,15654.
5. Zhang, C.; Wu, X.; Qu, J.; Chen, Y.* A General Enantioselective α-Alkyl Amino Acid Derivatives Synthesis Enabled by Cobalt-Catalyzed Reductive Addition. J. Am. Chem. Soc. DOI:10.1021/jacs.4c09556.
6. Zhang, C.; Wu, X.; Wang, C.; Zhang, C.; Qu, J.*; Chen, Y.* Pd/Cu-Catalyzed Domino Cyclization/Deborylation of AlkeneTethered Carbamoyl Chloride and 1,1-Diborylmethane. Org. Lett. 2020, 22, 6376.
7. Wang, C.; Zhao, W.; Wu, X.; Qu, J.*; Chen, Y.* Palladium-Catalyzed Regioselective Domino Spirocyclization of Carbamoyl Chlorides with Alkynes and Benzynes. Adv. Synth. Catal. 2020, 362, 4996.
8. Wu, X. #; Shrestha, M. #; Chen, Y.* Asymmetric Synthesis of α-Alkylated γ-Lactam via Nickel/8-Quinim-Catalyzed Reductive Alkyl-Carbamoylation of Unactived Alkene. Synlett. 2021, 32, 955. (invited Synpacts)
9. Shrestha, M.; Wu, X.; Huang, W.; Qu, J.; Chen, Y.* Recent Advances in Transition Metal-Catalyzed Reactions of Carbamoyl Chlorides. Org. Chem. Front. 2021, 8, 4024.
10. Wu, X.; Chen, Y.* Carbamoyl Fluoride-Promoted Ni-Catalyzed Asymmetric Carbamoyl-Arylation of Unactivated Alkenes. Chin. J. Org. Chem. 2021, 41, 867.
11. Liu, N.+; Wu, X.+; Wang, C.; Qu, J.; Chen, Y.* Nickel-Catalyzed Alkoxycarbonylation of Aryl Iodides with 1 atm CO. Chem. Commun., 2022, 58, 4643.
12. Wu, X.; Luan, B.; Zhao, W.; He, F.; Wu, X.-Y.; Qu, J.; Chen, Y.* Catalytic Desymmetric Dicarbofunctionalization of Unactivated Alkenes. Angew. Chem. Int. Ed. 2022, DOI: org/10.1002/anie.202111598.
13. Hou, L.; Huang, W.; Wu, X.; Qu, J.; Chen, Y.* Nickel-Catalyzed Carbonylation of Cyclopropanol with Benzyl Bromide for Multisubstituted Cyclopentenone Synthesis.Org. Lett. 2022, 24, 2699.
14. Luan B.; Tang Z.; Wu, X.*; Chen, Y.* 8-Quinolinyl Oxaoline: Ligand Exploration in Enantioselective Ni-Catalyzed Reductive Carbamoyl-Alkylation of Alkene to Access the Chiral Oxindoles. Synlett. 2022, DOI: 10.1055/a-1863-8957
15. Wu, X.+; Turlik, A. +; Luan, B.; He, F.; Qu, J.; Houk, K.N.; Chen, Y.* Nickel-Catalyzed Enantioselective Reductive Alkyl-Carbamoylation of Internal Alkenes. Angew. Chem. Int. Ed. 2022, https://doi.org/10.1002/anie.202207536.
16. Xia, T.; Xi, Y.; Ding, H.; Zhang, Y.; Fang, K.; Wu, X.; Qu, J,; Chen, Y.*Palladium(II)-Catalyzed Enantioselective Tntermolecular Oxidative Diarylation of Inter Enamides. Chem. Commun., 2022, https://doi.org/10.1039/D2CC03202C.
17. Wang, C.; Wu, X.; Li, H.; Qu, J.; Chen, Y.* Carbonylative Cross-Coupling Reaction of Allylic Alcohols and Organoalanes with 1 atm CO Enabled by Nickel Catalysis. Angew. Chem. Int. Ed. 2022, https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.202210484.
18. Zhang C.; Wu, X.; Xia, T.; Qu, J.; Chen, Y.* Ni-catalyzed Carbamoylation of Unactivated Alkenes for Stereoselective Construction of Six-Membered Lactams. Nat. Commun. 2022, https://doi.org/10.1038/s41467-022-33425-3.
19. Liu N.; Wu, X.*; Qu, J.; Chen, Y.* Nickel-Catalyzed Aminocarbonylation of Aryl Iodides with 1 atm CO. Chem-Asian J. 2023, 18, e202201061.
20. Weng, Y.+; Zhang, Y.+; Turlik, A.+; Wu, X.+; Li, H.; Fei, F.; Yao, Y.; Wang, C.; Guo, Z.; Qu, J.; Houk, K. N.*; Chen, Y.*Nickel-Catalysed Regio- and Stereoselective Acylzincation of Unsaturated Hydrocarbons with Organozincs and CO. Nat. Synth. 2023, 2, 261.
21. Wu, X.+; Li, H.+; He, F.; Qu, J.; Chen, Y.* Nickel/Quinim Enabled Asymmetric Carbamoyl-Acylation of Unactivated Alkenes. Chin. J. Chem. 2023, 41, 1673.
22.Wu, L.; Wu, X.*; Qu, J.; Chen, Y.* Exploration of Quinim Ligand in Ni-catalyzed Enantioselective Reductive Carbamoyl-Alkylation of Alkene. Chin. J. Org. Chem. 2023, DOI: 10.6023/cjoc202306006.
23.Wu, X.; Wang, C.; Liu, N.; Qu, J.; Chen, Y.* Nickel-Catalyzed Acylzincation of Allenes with Organozincs and CO. Nat. Commun. 2023, 14, 6960.
24.Wu, X.; Xia, H.; Gao, C.; Luan, B.; Wu, L.; Zhang, C.; Yang, D.; Hou, L.; Liu, N.; Xia, T.; Li, H.; Qu, J.; Chen, Y.* Modular α-tertiary amino ester synthesis through cobalt-catalysed asymmetric aza-Barbier reaction. Nat. Chem. 2024, 16, 398.
25.Wang, C.+; Liu, N.+;Wu, X.*; Qu, J.; Chen, Y.* Nickel-Catalyzed Regiodivergent Acylzincation of Styrenes with Organozincs and CO. Chin. J. Chem. 2024, 42, 599.
26. Wu, L.+; Xia, H.+; Bai, J.; Xi, Y.; Wu, X.; Gao, L.; Qu, J.; Chen, Y.* Diversified ring expansion of saturated cyclic amines enabled by azlactone insertion. Nat. Chem. 2024, 16, 1951.
27. Zhang, Y.; Cao, Q.; Xi, Y.; Wu, X.; Qu, J.; Chen, Y.* Nickel-Catalyzed Carbonylative Negishi Cross-Coupling of Unactivated Secondary Alkyl Electrophiles with 1 atm CO gas. J. Am. Chem. Soc. 2024, 146, 7971.
28. Xia, T.; Yu, Z.; Wu, X.; Qu, J.; Chen, Y.* Catalytic Reductive Addition of Imine for Chiral Amine Synthesis: Recent Advances and Future Perspectives. ChemCatChem. 2024, 0, e202401407.
29. Xia, T.; Wu, W.; Wu, X.*; Qu, J.; Chen, Y.* Cobalt-Catalyzed Enantioselective Reductive α-Chloro-Carbonyl Addition of Ketimine to Construct the β-Tertiary Amino Acid Analogues. Angew. Chem. Int. Ed. 2024, 63, e202318991.
30. Xia, T.; Wu, Y.; Hu, J.; Wu, X.*; Qu, J.; Chen, Y.* Cobalt-Catalyzed Asymmetric Aza-Nozaki-Hiyama-Kishi (NHK) Reaction of α-Imino Esters with Alkenyl Halides. Angew. Chem. Int. Ed. 2024, 63, e202316012.
31. Xia, H.; Jiang, X.; Lin, D.; Zhang, S.; Yu, Z.; Wu, X.; Chen, Y.* Catalytic Asymmetric Barbier Reaction of Ketones with Unactivated Alkyl Electrophiles. J. Am. Chem. Soc. 2024, 146, 28468.
32. Zhang, C.; Wu, X.; Qu, J.; Chen, Y.* A General Enantioselective α-Alkyl Amino Acid Derivatives Synthesis Enabled by Cobalt-Catalyzed Reductive Addition. J. Am. Chem. Soc. 2024, 146, 25918.
33. Wang, Q.; Bai, J.; Wu, X.*; Qu, J.; Chen, Y.* Iron-Catalyzed Radical Addition Reaction of Dehydroglycine with Aliphatic Carboxylic Acids. Org. Lett. 2025, 27, 10212.
34. Bai, J.; Wang, Q.; Zhao, W.; Shen, Y.; Xin, Y.; Wu, X.; Qu, J.; Chen, Y.* Iron-Catalyzed Asymmetric Cross-Electrophile Alkylation of Imines. ACS Catal. 2025, 15, 15112.
35. Liu, N.+; Xia, H.+; Shi, Y.+; Xu, K.; Yu, Z.; Wu, X.; Huang, G.*; Qu, J.; Chen, Y.* 8‑Quinox Cobalt Catalyst Enables the Reductive Alkylative Addition of Sulfinylamines with Unactivated Alkyl Halides. J. Am. Chem. Soc. 2025, 147, 26786.
36. Zhao, W.; Shen, Y.; Wu, X.; Xia, T.; Hu, J.; Qu, J.; Chen, Y.* Cobalt-Catalyzed Asymmetric Reductive Coupling of Isocyanates with Tertiary Alkyl Halides for Sterically Bulky Chiral Amide Synthesis. J. Am. Chem. Soc. 2025, 147, 27155.
37. Wu, X.+; Xia, T.+; Bai, J.+; Shi, Y.+; Fang, C.; Hu, J.; Wu, W.; Zhang, C.; Wang, Q.; Huang, G.*; Qu, J.; Chen, Y.* Enantioconvergent Radical Addition of Racemic Alkyl Halides to Access Vicinal Stereocentres. Nat. Chem. 2025, 10.1038/s41557-025-01967-w.
38. Wu, X.; Shi, Y.; Zhang, C.; Xu, K.; Xia, T.; Huang, G.*; Qu, J.; Chen, Y.* Nat. Synth. 2025, Accepted in Pricinple.
39. Xia, T.+; Wang, Z.+; Zhang, X.; Hu, J.; Zhang, S.; Zhang, Y.; Gu, H.; Wu, X.; Zhu, W.-H.; Qu, J.; Chen, Y.* Enantioselective Redox-Neutral Radical Addition of α-Imino Esters with Sulfonyl Hydrazides. J. Am. Chem. Soc. 2025, https://doi.org/10.1021/jacs.5c16138.