课题组面向国家及社会发展的重大需求，瞄准世界合成化学前沿领域的基础科学问题，发展新医药、新农药、新材料等高端化学品的高效绿色合成策略。在研究方法上，侧重于通过设计合成新型的手性催化剂，深入研究催化反应机理，提高催化反应的效率和选择性，通过光、电、酶赋能策略替代传统合成领域中使用的高危、高毒化学试剂，实现高附加值功能分子的高效精准合成及工业化应用研究。迄今为止，以第一作者/通讯作者共发表Nature, Science, J. Am. Chem. Soc., Angew. Chem. Int. Ed., Adv. Sci., JACS Au, CCS Chem., Chem. Sci. 等SCI论文80余篇，文章他引>3300次，h指数31。同时，授权中国专利6项，参与撰写3部外文图书。
研究方向：
1. Electrocatalysis
2. Transition-metal Catalysis
3. Biocatalysis
代表性科研论文：
1. Electrophotocatalytic Oxygenation of Multiple Adjacent C–H Bonds
Nature 2023, 614, 275-280.
2. Alternating the current direction
Science 2023, 380, 34-35. (Perspective)
3. Electrochemical Migratory Cyclization of N-Acylsulfonamides
Angew. Chem. Int. Ed. 2022, 61, e202206058.
4. Electrochemical Conversions of Sulfenamides into Sulfonimidoyl- and Sulfondiimidoyl Fluorides
JACS Au. 2025, 5, 2359-2367.
5. Benzo-Extended [n]Phenacenes: e-Flow Synthesis and Length-dependent Properties
JACS Au. 2025, 5, 4281-4287.
6. Ligand-Engineered Metal-Organic Frameworks of Three-Dimensional Infinite Trinuclear Zinc Units for Photocatalytic Monooxygenation of Sulfenamides
Adv. Sci., 2025, 12, e06037.
7. Synthesis of Chiral Sulfinamides Enabled by Polycyclic Ketone Monooxygenase Catalyzed Asymmetric Oxidation of Sulfenamides
ACS Catal. 2025, 15, 16247-16253.
8. A General Electrochemical Synthesis of Sulfonimidoyl Fluorides, Azides, and Acetates
CCS Chem. 2024, 6, 2021-2030.
9. Electrochemical Multicomponent Reaction toward C−H Tetrazolation of Alkyl Arenes and Vicinal Azidotetrazolation of Alkenes
Chem. Sci. 2022, 13, 13851-13856.
10. Electrochemical Cascade Migratory versus ortho-Cyclization of 2-Alkynylbenzenesulfonamides
Chem. Sci. 2024, 15, 2827-2832.
11. Thiophene-backbone Arcuate Graphene Nanoribbons: Shotgun Synthesis and Length-dependent Properties
Chem. Sci. 2025, 16, 7366-7373.
Funding agencies and cooperating organizations
