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成果及论文

(Selected publications in three years):

1. Zhang Z, Xiang L, Wang Y, Jiang Y, Cheng Y, Xiao GG, Ju D, Chen Y. Effect of Diosgenin on the Circulating MicroRNA Profile of Ovariectomized Rats. Front Pharmacol. 2020 Mar 6;11:207. doi: 10.3389/fphar.2020.00207. eCollection 2020. PMID: 32210807.

2. Yang MW, Tao LY, Jiang YS, Yang JY, Huo YM, Liu DJ, Li J, Fu XL, He R, Lin C, Liu W, Zhang JF, Hua R, Li Q, Jiang SH, Hu LP, Tian GA, Zhang XX, Niu N, Lu P, Shi J, Xiao GG, Wang LW, Xue J, Zhang ZG, Sun YW. Perineural invasion reprograms the immune microenvironment through cholinergic signaling in pancreatic ductal adenocarcinoma. Cancer Res. 2020 Feb 25. pii: canres.2689.2019. doi: 10.1158/0008-5472.CAN-19-2689. [Epub ahead of print]PMID: 32098780.

3. Xiao GG, Targeting Serotonin System in Pancreatic Cancer, Pancreas. 2020 Jan;49(1):e1. doi: 10.1097/MPA.0000000000001417.

4. Xufeng Tao, Qing Chen, Ning Li, Hong Xiang, Yue Pan, Yueyang Qu, Dong Shang, Vay Liang W Go, Jing Xue, Yongwei Sun, Zhigang Zhang, Junchao Guo, Gary Guishan Xiao* Serotonin-RhoA/ROCK axis promotes acinar-to-ductal metaplasia and early lesions of pancreatic ductal adenocarcinoma. Biomed Pharmacother. 2020 May;125:109999. doi: 10.1016/j.biopha.2020.109999. Epub 2020 Feb 25.

5. Jianzhou Liu†, Xiaoyu Miao†, Bowen Xiao, Jing Huang, Xufeng Tao, Jiong Zhang,Hua Zhao,Yue Pan, Hongwei Wang, Ge Gao, Gary Guishan Xiao* Obg-like ATPase 1 enhances chem-resistance of breast cancer via activation of TGF-β/Smad axis cascades. Front Pharmacol., 2020 (in press).

6. Xiao GG, Zhang Z, Lu B, Wang H, Fan TW, Boros LG, Gao P, Pan Y, Go VLW. Proceedings of the 3rd International Conference for Cancer Metabolism and Therapy, October 12-14, 2018, Shanghai, China. Pancreas. 2020 Feb;49(2):149-157. doi: 10.1097/MPA.0000000000001482.PMID: 32049950.

7. Jun-Chao Guo#*, Peng Zhang#, Li Zhou#, Lei You#, Xufeng Tao#, Qiao-Fei Liu, Zhi-Gang Zhang, Bei Sun, Zhi-Yong Liang, Da Yuan, Aidi Tan, Jian Sun, Quan Liao, Meng-Hua Dai, Tai-Ping Zhang*, Gary Guishan Xiao*, Shao Li*, Yu-Pei Zhao* Development and Validation  of a Network-Based Signature for the Outcome of Pancreatic Ductal Adenocarcinoma Ebiomedicine 2020 (in press).

8. Wang H, Liu C, Zhao Y, Zhang W, Xu K, Li D, Zhou Y, Li H, Xiao G*, Lu B, Gao G. Inhibition of LONP1 protects against erastin-induced ferroptosis in Pancreatic ductal adenocarcinoma PANC1 cells. Biochem Biophys Res Commun. 2019 Dec 7.

9. Xian L, Xu F, Liu J, Xu N, Li H, Ge H, Shao K, Fan J, Xiao G*, Peng X*. MicroRNA Detection with Turnover Amplification via Hybridization-mediated Staudinger Reduction for Pancreatic Cancer Diagnosis. J Am Chem Soc. 2019 Nov 27. doi: 10.1021/jacs.9b11272. [Epub ahead of print] PMID: 31774664.

10. Hu LP*, Zhang XX*, Jiang SH*, Tao LY, Li Q, Zhu LL, Yang MW, Huo YM, Jiang YS, Tian GA, Cao XY, Zhang YL, Qin Yang, Xiao-Mei Yang, Ya-Hui Wang, Jun Li, Gary Guishan Xiao†,Yongwei Sun†, Zhi-Gang Zhang† Targeting Purinergic Receptor P2Y2 prevents the growth of pancreatic ductal adenocarcinoma by inhibiting cancer cell glycolysis Clin Cancer Res. 2019 Feb 15;25(4):1318-1330.

11. Pan Y, Zhang Y, Chen Q, Tao X, Liu J, Xiao GG. CTAB Enhances Chemo-Sensitivity Through Activation of AMPK Signaling Cascades in Breast Cancer. Front Pharmacol. 2019 Jul 26;10:843.

12. Niu N, Lu P, Yang Y, He R, Zhang L, Shi J, Wu J, Yang M, Zhang ZG, Wang LW, Gao WQ, Habtezion A, Xiao GG, Sun Y, Li L, Xue J. Loss of Setd2 promotes Kras-induced acinar-to-ductal metaplasia and epithelia-mesenchymal transition during pancreatic carcinogenesis. Gut. 2019 Jul 11. pii: gutjnl-2019-318362.

13. Liu C, Wang H, Li H, Chen X, Wu X, Lu B, Zhang W, Zhou Y, Xiao GG*, Gao G*. Inhibition of LONP1 Suppresses Pancreatic Cancer Progression Via c-Jun N-Terminal Kinase Pathway-Meditated Epithelial-Mesenchymal Transition. Pancreas. 2019 May/Jun;48(5):629-635.

14. Min Cao, Lijuan Zheng, Jianzhou Liu, Thomas Dobleman, Shen Hu, Vay Liang W. Go, WN Paul Lee, Gao Ge, Gary Guishan Xiao*. MicroRNAs as effective surrogate biomarkers for early diagnosis of oral cancer. Clin Oral Invest.. 2018 Mar;22(2):571-581

15. Pan Y, Cao M, Liu J, Yang Q, Miao X, Go VLW, Lee PWN, Xiao GG*. Metabolic Regulation in Mitochondria and Drug Resistance. Adv Exp Med Biol. 2017;1038:149-171. doi: 10.1007/978-981-10-6674-0_11.PMID: 29178075

16. Zhang Z, Chen Y, Xiang L, Wang Z, Xiao GG*, Hu J. Effect of Curcumin on the Diversity of Gut Microbiota in Ovariectomized Rats. Nutrients. 2017 Oct 19;9(10). pii: E1146. doi: 10.3390/nu9101146. PMID: 29048369

17. Zhang ZG, Chen YJ, Xiang LH, Pan JH, Wang Z, Xiao GG*, Ju DH. Protective effect of Rhizoma Dioscoreae extract against alveolar bone loss in ovariectomized rats via regulation of IL-6/STAT3 signaling. Int J Mol Med. 2017 Sep 8. doi: 10.3892/ijmm.2017.3130.

18. Xiao GG*, Wang H, Wang L, Zhang W, Gao G, Zhang X, Lee WP, Lu Z, Chen J, Gao P, Lu B, Tang KF, Shi L, Go VLW. Proceedings of the 1st International Conference for Cancer Metabolism and Therapy, October 14-17, 2016, Dalian, China. Pancreas. 2017 Aug;46(7):953-963.

19. Cui L, Elzakra N, Xu S, Xiao GG, Yang Y, Hu S. Investigation of three potential autoantibodies in Sjogren's syndrome and associated MALT lymphoma. Oncotarget. 2017 May 2;8(18):30039-30049.