刘朝雷，安徽芜湖人，2018年7月进入基因编辑与无融合生殖课题组，主要从事水稻加倍单倍体育种技术、杂交水稻无融合生殖体系优化，以及基因编辑改良水稻育种等方面研究。
发表论文及专著情况
1) Zhengyuan Hong, Linghong Zhu, Chaolei Liu, Kejian Wang, Yuchun Rao* and Hongwei Lu*. Genome-Wide Identification and Evolutionary Analysis of Functional BBM-like Genes in Plant Species, Genes, 2024, 15(12):1614.
2) Wenqiang Chen, Liping Xu, Yuchun Rao, Chaolei Liu, Zhengyuan Hong, Hongwei Lu, Chun-Ming Liu, Hong-Ju Li*, Kejian Wang*. Self-propagated clonal seed production in dicotyledonous Arabidopsis, Science Bulletin, 2024.
3) Chaolei Liu†, Song Yan†, Fangming Mao, Tingting Sun, Huan Liang, Qing Liu, Qian Qian*, Kejian Wang*. Large-scale production of rice haploids by combining superior haploid inducer with PTGMS lines, Plant Communications, 2024.
4) Huijing Yan†, Xiaozhen Jiao†, Yuye Chen, Huan Liang, Weihong Liang*, Chaolei Liu*. Knockout of OsHMA3 in an indica rice increases cadmium sensitivity andinhibits plant growth, Plant Growth Regulation, 2024.
5) Yong Huang†, Yuqing Liang†, Yingying Xie, Yuchun Rao, Jie Xiong, Chaolei Liu, Chun Wang, Xingchun Wang*, Qian Qian*and Kejian Wang*. Efficient haploid induction via egg cell expression of dandelion PARTHENOGENESIS in foxtail millet (Setaria italica), Plant Biotechnology Journal, 2024,22(7):1797-1799.
6) 陈玉叶#，焦晓真#，王健，王克剑，陈峰，朱克明*，刘朝雷*. 利用 CBE系统编辑 Wx基因调控稻米直链淀粉含量, 中国水稻科学, 2024.
7) 胡风越，王健，王春，王克剑* 刘朝雷*. 水稻 DMP1-3 基因突变体的创制及其单倍体诱导能力鉴定, 中国水稻科学, 2024.
8) Chaolei Liu†, Jian Wang†, Hongwei Lu, Yong Huang, Huijing Yan, Huan Liang, Chun Wang*, Kejian Wang*. Engineering synthetic apomixis in different hybrid rice varieties using the Fix strategy, New Crops, 2023,1:100003.
9) Jian Wang, Huijing Yan, Xiaozhen Jiao, Jun Ren, Fengyue Hu, Huan Liang, Weihong Liang and Chaolei Liu, Development of Specific Molecular and Phenotypic Marker-Based Haploid Inducers in Rice, Agronomy-Basel, 2023, 13(6): 1520.
10) Chaolei Liu, Zexue He, Yan Zhang, Fengyue Hu, Mengqi Li, Qing Liu, Yong Huang, Jian Wang, Wenli Zhang*, Chun Wang* and Kejian Wang*. Synthetic apomixis enables stable transgenerational transmission of heterotic phenotypes in hybrid rice, Plant Communications, 2023, 4(2): 100470.
11) Jie Xiong, Fengyue Hu, Jun Ren, Yong Huang, Chaolei Liu and Kejian Wang*. Synthetic apomixis: the beginning of a new era, Current Opinion in Biotechnology, 2023, 79: 102877.
12) Xin Wei, Chaolei Liu, Xi Chen, Hongwei Lu, Jian Wang, Shenlin Yang, Kejian Wang*. Synthetic apomixis with normal hybrid rice seed production, Molecular Plant, 2023,16(3): 489-492.
13) Xin Wei, Qing Liu, Tingting Sun, Xiaozhen Jiao, Chaolei Liu, Fengyue Hu, Xi Chen and Kejian Wang*. Manipulation of genetic recombination by editing the transcriptional regulatory regions, Plant Communications, 2023, 4(2): 100474.
14) Jian Wang, Yuexuan Cao, Kejian Wang and Chaolei Liu *. Development of Multiple Heading Date mtl Haploid Inducer Lines in Rice, Agriculture-Basel, 2022,12(6):806.
15) 曹跃炫，严绘景，王克剑，刘朝雷*. 苗期快速分选水稻人工无融合生殖克隆种子, 中国水稻科学, 2022, 36(6): 656-662.
16) Liu C#, Cao Y#, Hua Y#, Du G, Liu Q, Wei X, Sun T, Lin J, Wu M, Cheng Z, Wang K*. Concurrent Disruption of Genetic Interference and Increase of Genetic Recombination Frequency in Hybrid Rice Using CRISPR/Cas9. Front Plant Sci. 2021, 12:757152.
17) Ding SL#, Liu CL#, Shang LG, Yang SL, Zhang AP, Jiang HZ, Ruan BP, Fang GN, Tian B, Ye GY, Guo LB, Qian Q*, Gao ZY* Identification of QTLs for cadmium tolerance during seedling stage and validation of qCDSL1 in rice. Rice Science, 2021, 28( 1), 81-88.
18) Yu J#, Liu C#, Lin H#, Zhang B, Li X, Yuan Q, Liu T, He H, Wei Z, Ding S, Zhang C, Gao H, Guo L, Wang Q, Qian Q*, Shang L*. Loci and natural alleles for cadmium-mediated growth responses revealed by a genome wide association study and transcriptome analysis in rice. BMC Plant Biol. 2021, 21(1):374.
19) Liu C, Wang C, Wang K Generating Clonal Seeds from Hybrid Rice with CRISPR-Cas9. In: Islam M.T., Molla K.A. (eds) CRISPR-Cas Methods. Springer Protocols Handbooks, 2021, Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1657-4_14
20) Liu CL#, Gao ZY#, Shang LG#, Yang CH, Ruan BP, Zeng DL, Guo LB, Zhao FJ, Huang CF*, Qian Q* Natural variation in the promoter of OsHMA3 contributes to differential grain cadmium accumulation between Indica and Japonica rice. J Integr Plant Biol, 2020, 62(3):314-329. (JIPB杂志2020年度最佳研究论文，高被引论文)
21) Liu C#, Ding S#, Zhang A, Hong K, Jiang H, Yang S, Ruan B, Zhang B, Dong G, Guo L, Zeng D, Qian Q*, Gao Z* Development of nutritious rice with high zinc/selenium and low cadmium in grains through QTL pyramiding, J Integr Plant Biol, 2020, 62(3):349-359.
22) Zhao C#, Liu C*#, Zhang Y, Cui Y, Hu H, Jahan N, Lv Y, Qian Q, Guo L* A 3-bp deletion of WLS5 gene leads to weak growth and early leaf senescence in rice, Rice, 2019, 12(1):26.
23) Liu C, Chen G, Li Y, Peng Y, Zhang A, Hong K, Jiang H, Ruan B, Zhang B, Yang S, Gao Z*, Qian Q*. Characterization of a major QTL for manganese accumulation in rice grain. Sci Rep. 2017, 7(1):17704.
24) Chen G#, Liu C#, Gao Z, Zhang Y, Jiang H, Zhu L, Ren D, Yu L, Xu G*, Qian Q*. OsHAK1, a High-Affinity Potassium Transporter, Positively Regulates Responses to Drought Stress in Rice. Front Plant Sci. 2017, 8:1885.
25) Zhang A#, Liu C#, Chen G, Hong K, Gao Y, Tian P, Peng Y, Zhang B, Ruan B, Jiang H, Guo L, Qian Q, Gao Z*. Genetic analysis for rice seedling vigor and fine mapping of a major QTL qSSL1b for seedling shoot length. Breed Sci. 2017, 67(3):307-315.
26) Gao Y#, Liu C#, Li Y, Zhang A, Dong G, Xie L, Zhang B, Ruan B, Hong K, Xue D, Zeng D, Guo L, Qian Q, Gao Z*. QTL analysis for chalkiness of rice and fine mapping of a candidate gene for qACE9. Rice (N Y). 2016, 9(1):41.
27) Xu J#, Liu C#, Li M, Hu J, Zhu L, Zeng D, Yang Y, Peng Y, Ruan B, Guo L*, Li H*. A rice DEAD-box RNA helicase protein, OsRH17, suppresses 16S ribosomal RNA maturation in Escherichia coli. Gene. 2015, 555(2):318-28.
专利
一种利用多倍体杂种优势的植物育种方法，ZL202110696444.3，王克剑，刘朝雷，王春，刘庆，黄勇，焦晓真
申请项目情况
1）国家自然基金-面上项目：HSS8提高无融合生殖杂交水稻Fix结实率研究，32372177，2024.1.1-2027.12.31，经费50万元，主持；
2） 杂交水稻全国重点实验室开放课题：水稻无融合生殖相关基因挖掘，2022KF01，2022.8-2024.7，经费10万，主持；
3）中国农业科学院青年创新专项：提高杂交水稻无融合生殖体系结实率研究，Y2022QC20，2022.1.1-2024.12.31，经费150万，主持；
4） 国家自然科学基金青年科学基金项目：携表型遗传标记水稻单倍体诱导系的创制与应用，32001527，2021.1.1-2023.12.31，经费24万，主持；
5）国家联合基金项目：水稻无融合生殖分子机理研究，U20A2030，2021.1.1-2024.12.31，参与；
6）国家自然科学基金国际(地区)合作与交流项目：水稻硝态氮转运同化的遗传机理研究及氮高效种质的发掘创制，3201101583，2021.1.1-2025.12.31，参与。