近期论文：
1. Bing-Bing Wu, Jie Xu, Qian Gao, Kang-Jie Bian, Guo-Kai Liu,* and Xi-Sheng Wang*, “A General and Efficient Solution to Monofluoroalkylation: Divergent Synthesis of Aliphatic Monofluorides with Modular Synthetic Scaffolds”, Angew. Chem. Int. Ed. 2022, e202208938.
2. Wei Xiong, Wen-Bing Qin, Ya-Shi Zhao, Kai-Zhong Fu and Guo-Kai Liu*，“Direct C(sp 3 )–H difluoromethylation via radical–radical cross-coupling by visible-light photoredox catalysis”, Org. Chem. Front., 2022, 9, 2141–2148.
3. Wen-Bing Qin, Wei Xiong, Ya-Shi Zhao, Kai-Zhong Fu, Lei Su, and Guo-Kai Liu*，“Difluoromethyl Radical Triggered Tandem Reaction of N‑Allyl Amides to Difluoromethylated β‑Amino Alcohols by Photoredox Catalysis”, Org. Lett. 2021, 23（21）, 8482−8487.
4. Wen-Bing Qin; Wei Xiong; Xin Li; Jia-Yi Chen; Li-Ting Lin; Henry N. C. Wong, and Guo-Kai Liu*, “Visible-light-driven difluoromethylation of isocyanides with S‑(difluoromethyl)sulfonium salt: Access to a wide variety of difluoromethylated phenanthridines and isoquinolines”, J. Org. Chem. 2020, 85, 10479-10487.
5. Wen-Bing Qin;# Jian-Jian Liu;# Zhongyan Huang;# Xin Li; Wei Xiong; Jia-Yi Chen; Guo-Kai Liu*, “Bench-stable S-(monofluoromethyl)sulfonium salts : highly efficient C- and O-regioselective monofluoromethylation of 1,3-dicarbonyl compounds”, Eur. J. Org. Chem. 2020, 5862-5866.
6. Ziyang Wang； Anqi Huang；Fang Fang；Pengfei Li*；Guo-Kai Liu*；and Wenjun Li*，“Non-hydrogen bond catalyst-mediated diastereoselective conjugate additions of 5H-oxazol-4-ones to o-hydroxyphenyl-substituted p-quinone methides”，Org. Biomol. Chem. 2020, 18, 6807–6811.
7. Wen-Bing Qin; Jia-Yi Chen; Wei Xiong; Guo-Kai Liu*, “Recent Advance in Development and Application of Electrophilic Difluoromethylating reagents”, Chin. J. Org. Chem. 2020, 40, 3177–3195.
8. Wen-Bing Qin；Qinxin Lou；Wei Xiong；Guo-Kai Liu*,“Organocatalytic enantioselective conjugate addition of nitroalkanes to trifluoromethylated 3-methyleneoxindoles”，Tetrahedron Letters 2020, 61，152443.
9. Guo-Kai Liu#*; Wen-Bing Qin#; Xin Li; Li-Ting Lin; Henry N. C. Wong, “Difluoromethylation of Phenols and Thiophenols with the S‑(Difluoromethyl)sulfonium Salt: Reaction, Scope, and Mechanistic Study”, J. Org. Chem. 2019, 84, 15948-15957.
10. Guo-Kai Liu#*; Xin Li#; Wen-Bing Qin; Xiao-Shui Peng; Henry N. C. Wong; Linxing Zhang; Xinhao Zhang, “Facile difluoromethylation of aliphatic alcohols with an S-(difluoro-methyl)sulfonium salt: reaction, scope and mechanistic study”, Chem. Commun. 2019, 55, 7446-7449.
11. Sheng-Le Lu#, Xin Li#, Wen-Bing Qin, Jian-Jian Liu, Yi-Yong Huang, Henry N. C. Wong, and Guo-Kai Liu,* “Air- and Light-Stable S-(Difluoromethyl)sulfonium Salts: C-Selective Electrophilic Difluoromethylation of β-Ketoesters and Malonates”, Org. Lett. 2018, 20, 6925-6929.
12. Qinxin Lou, Yuyang Ding, Dengfeng Xu, Guo-Kai Liu,* and Junling Zhao, “Organocatalytic Enantioselective Synthesis of Dihydropyranoindole Derivatives Bearing Trifluoromethylated All-Carbon-Substituted Stereocenters”, Adv. Synth. Catal. 2017, 359, 2557 – 2563.
13. Guo-Kai Liu*, Xin Li, Wen-Bing Qin, Wei-Feng Lin, Li-Ting Lin, Jia-Yi Chen, Jian-Jian Liu， “Selective O-difluoromethylation of 1,3-diones using S-(difluoromethyl) sulfonium salt”, Chin. Chem. Lett. 2019, 30,1515-1518.
14. Xin Wang#, Guokai Liu# (contributed equally), Xiu-Hua Xu, Naoyuki Shibata, Etsuko Tokunaga, and Norio Shibata*, “S-((Phenylsulfonyl)difluoromethyl)thiophenium Salts: Carbon-Selective Electrophilic Difluoromethylation of β-Ketoesters, β-Diketones, and Dicyanoalkylidenes”, Angew. Chem. Int. Ed. 2014, 53, 1827 –1831.
15. Guokai Liu, Xin Wang, Xiu-Hua Xu, Xu Lu, Etsuko Tokunaga, Norio Shibata*, “Selective O-Difluoromethylation of 1,3-Diones by Bromodifluoromethylating Reagent”, Org. Lett. 2013, 15(5), 1044-1047.
授权和申请专利
[1]中国发明专利，刘国凯，陆声乐，李鑫，秦文兵。一种二氟甲基化试剂及其制备方法与应用，专利号：ZL201811022609.3, 授权公告号：CN108997183B。
[2]国际PCT专利，刘国凯，陆声乐，李鑫，秦文兵。 一种二氟甲基化试剂及其制备方法与应用，国际公布号：WO2020047985A1,国际申请号：CN2018113547
[3]中国发明专利，刘国凯，李鑫，秦文兵。 烷基二氟甲基醚类化合物的合成方法，专利号：ZL201910453848.2, 授权公告号：CN110028390B。
[4] 中国发明专利，刘国凯，熊威，秦文兵。一种二氟甲基反应方法及应用。202210201181.9。
